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Select item 114010341.

Proximity labeling reveals dynamic changes in the SQSTM1 protein network

Alejandro N. Rondón-Ortiz, Lushuang Zhang, Peter E.A. Ash, Avik Basu, Sambhavi Puri, Sophie J.F. van der Spek, Zihan Wang, Luke Dorrian, Andrew Emili, Benjamin Wolozin

J Biol Chem. 2024 Sep; 300(9): 107621. Published online 2024 Aug 3. doi: 10.1016/j.jbc.2024.107621

PMCID:: PMC11401034

Abstract Article PDF–5.4M

Select item 113159292.

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex

Marisa Bedir, Emily Outwin, Rita Colnaghi, Lydia Bassett, Iga Abramowicz, Mark O’Driscoll

EMBO Rep. 2024 Aug; 25(8): 3432–3455. Published online 2024 Jun 28. doi: 10.1038/s44319-024-00184-9

PMCID:: PMC11315929

Abstract Article PDF–3.4M

Select item 112099353.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 111426894.

IGF2BP3 regulates the expression of RRM2 and promotes the progression of rheumatoid arthritis via RRM2/Akt/MMP-9 pathway

Zhaonan Ban, Zhengjiang Li, Shuxing Xing, Yongjie Ye

PLoS One. 2024; 19(5): e0303593. Published online 2024 May 31. doi: 10.1371/journal.pone.0303593

PMCID:: PMC11142689

Abstract Article PDF–2.7M

Select item 110259325.

A comprehensive analysis of ribonucleotide reductase subunit M2 for carcinogenesis in pan-cancer

Yong Wang, Rong Chen, Jing Zhang, Peng Zeng

PLoS One. 2024; 19(4): e0299949. Published online 2024 Apr 18. doi: 10.1371/journal.pone.0299949

PMCID:: PMC11025932

Abstract Article PDF–5.2M

Select item 107317026.

Targeting of RRM2 suppresses DNA damage response and activates apoptosis in atypical teratoid rhabdoid tumor

Le Hien Giang, Kuo-Sheng Wu, Wei-Chung Lee, Shing-Shung Chu, Anh Duy Do, Chun A. Changou, Huy Minh Tran, Tsung-Han Hsieh, Hsin-Hung Chen, Chia-Ling Hsieh, Shian-Ying Sung, Alice L. Yu, Yun Yen, Tai-Tong Wong, Che-Chang Chang

J Exp Clin Cancer Res. 2023; 42: 346. Published online 2023 Dec 20. doi: 10.1186/s13046-023-02911-x

PMCID:: PMC10731702

Abstract Article PDF–5.0M

Select item 103986607.

C9orf72 protein quality control by UBR5‐mediated heterotypic ubiquitin chains

Julia Jülg, Dieter Edbauer, Christian Behrends

EMBO Rep. 2023 Aug; 24(8): e55895. Published online 2023 Jun 15. doi: 10.15252/embr.202255895

PMCID:: PMC10398660

Abstract Article PDF–2.4M

Select item 102374228.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 102284089.

MiR-17- 5p/RRM2 regulated gemcitabine resistance in lung cancer A549 cells

Xuan Ma, Tian Fu, Zhi-Yin Ke, Shen-Lin Du, Xue-Chun Wang, Ning Zhou, Mu-Yi Zhong, Yong-Jun Liu, Ai-Ling Liang

Cell Cycle. 2023; 22(11): 1367–1379. Published online 2023 Apr 28. doi: 10.1080/15384101.2023.2207247

PMCID:: PMC10228408

Abstract Article PDF–1.5M

Select item 1019144610.

Ribonucleotide reductase regulatory subunit M2 drives glioblastoma TMZ resistance through modulation of dNTP production

Ella N. Perrault, Jack M. Shireman, Eunus S. Ali, Peiyu Lin, Isabelle Preddy, Cheol Park, Shreya Budhiraja, Shivani Baisiwala, Karan Dixit, C. David James, Dieter H Heiland, Issam Ben-Sahra, Sebastian Pott, Anindita Basu, Jason Miska, Atique U. Ahmed

Sci Adv. 2023 May; 9(20): eade7236. Published online 2023 May 17. doi: 10.1126/sciadv.ade7236

PMCID:: PMC10191446

Abstract Article PDF–2.4M

Select item 1015161511.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 999251912.

Ribonucleotide reductase subunit switching in hepatoblastoma drug response and relapse

Anthony Brown, Qingfei Pan, Li Fan, Emilie Indersie, Cheng Tian, Nikolai Timchenko, Liyuan Li, Baranda S. Hansen, Haiyan Tan, Meifen Lu, Junmin Peng, Shondra M. Pruett-Miller, Jiyang Yu, Stefano Cairo, Liqin Zhu

Commun Biol. 2023; 6: 249. Published online 2023 Mar 8. doi: 10.1038/s42003-023-04630-7

PMCID:: PMC9992519

Abstract Article PDF–15M

Select item 991671413.

NMR Analysis Suggests Synergy between the RRM2 and the Carboxy-Terminal Segment of Human La Protein in the Recognition and Interaction with HCV IRES

Aikaterini I. Argyriou, Georgios A. Machaliotis, Garyfallia I. Makrynitsa, Eleni G. Kaliatsi, Constantinos Stathopoulos, Georgios A. Spyroulias

Int J Mol Sci. 2023 Feb; 24(3): 2572. Published online 2023 Jan 29. doi: 10.3390/ijms24032572

PMCID:: PMC9916714

Abstract Article PDF–3.7M

Select item 987841914.

PRMT1通过促进RRM2表达抑制鼻咽癌细胞凋亡

周兰柱, 吴俊, 张明洁, 赵报, 马士崟

Nan Fang Yi Ke Da Xue Xue Bao. 2022 Dec 20; 42(12): 1783–1790. Chinese. doi: 10.12122/j.issn.1673-4254.2022.12.05

PMCID:: PMC9878419

Abstract Article PDF–2.4M

Select item 959621615.

Comprehensive bioinformatics analysis of ribonucleoside diphosphate reductase subunit M2(RRM2) gene correlates with prognosis and tumor immunotherapy in pan-cancer

Liyuan Wu, Le Yin, Linxiang Ma, Jiarui Yang, Feiya Yang, Baofa Sun, Xing Nianzeng

Aging (Albany NY) 2022 Oct 15; 14(19): 7890–7905. Published online 2022 Oct 3. doi: 10.18632/aging.204315

PMCID:: PMC9596216

Abstract Article PDF–2.6M

Select item 948193316.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 927928517.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 926085618.

FBXO38 Ubiquitin Ligase Controls Centromere Integrity via ZXDA/B Stability

Nikol Dibus, Vladimir Korinek, Lukas Cermak

Front Cell Dev Biol. 2022; 10: 929288. Published online 2022 Jun 23. doi: 10.3389/fcell.2022.929288

Correction in:: Front Cell Dev Biol. 2022; 10: 1000878.

PMCID:: PMC9260856

Abstract Article PDF–2.8M

Select item 917141119.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 889702220.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

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