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Select item 114057551.

Contribution of A1 to macrophage survival in cooperation with MCL-1 and BCL-X_L in a murine cell model of myeloid differentiation

Juliane Vier, Georg Häcker, Susanne Kirschnek

Cell Death Dis. 2024 Sep; 15(9): 677. Published online 2024 Sep 16. doi: 10.1038/s41419-024-07064-z

PMCID:: PMC11405755

Abstract Article PDF–904K

Select item 73031762.

The pro-survival Bcl-2 family member A1 delays spontaneous and FAS ligand-induced apoptosis of activated neutrophils

Robyn L. Schenk, Lahiru Gangoda, Kate E. Lawlor, Lorraine A. O’Reilly, Andreas Strasser, Marco J. Herold

Cell Death Dis. 2020 Jun; 11(6): 474. Published online 2020 Jun 18. doi: 10.1038/s41419-020-2676-9

PMCID:: PMC7303176

Article PDF–571K

Select item 58642403.

Anti-apoptotic A1 is not essential for lymphoma development in Eµ-Myc mice but helps sustain transplanted Eµ-Myc tumour cells

Mark Mensink, Natasha S. Anstee, Mikara Robati, Robyn L. Schenk, Marco J. Herold, Suzanne Cory, Cassandra J. Vandenberg

Cell Death Differ. 2018 Apr; 25(4): 795–806. Published online 2018 Jan 16. doi: 10.1038/s41418-017-0045-8

PMCID:: PMC5864240

Abstract Article PDF–982K

Select item 54252544.

Epstein-Barr virus ensures B cell survival by uniquely modulating apoptosis at early and late times after infection

Alexander M Price, Joanne Dai, Quentin Bazot, Luv Patel, Pavel A Nikitin, Reza Djavadian, Peter S Winter, Cristina A Salinas, Ashley Perkins Barry, Kris C Wood, Eric C Johannsen, Anthony Letai, Martin J Allday, Micah A Luftig

eLife. 2017; 6: e22509. Published online 2017 Apr 20. doi: 10.7554/eLife.22509

PMCID:: PMC5425254

Abstract Article PDF–3.0M

Select item 54231125.

Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell populations both in vitro and in vivo

Emma M Carrington, Yifan Zhan, Jamie L Brady, Jian-Guo Zhang, Robyn M Sutherland, Natasha S Anstee, Robyn L Schenk, Ingela B Vikstrom, Rebecca B Delconte, David Segal, Nicholas D Huntington, Philippe Bouillet, David M Tarlinton, David CS Huang, Andreas Strasser, Suzanne Cory, Marco J Herold, Andrew M Lew

Cell Death Differ. 2017 May; 24(5): 878–888. Published online 2017 Mar 31. doi: 10.1038/cdd.2017.30

PMCID:: PMC5423112

Abstract Article PDF–862K

Select item 53957006.

MYC selects against reduced BCL2A1/A1 protein expression during B cell lymphomagenesis

M Sochalska, F Schuler, J G Weiss, M Prchal-Murphy, V Sexl, A Villunger

Oncogene. 2017 Apr; 36(15): 2066–2073. Published online 2016 Oct 3. doi: 10.1038/onc.2016.362

PMCID:: PMC5395700

Abstract Article PDF–2.1M

Select item 53834477.

Constitutive expression of the anti‐apoptotic Bcl‐2 family member A1 in murine endothelial cells leads to transplant tolerance

L. A. Smyth, L. Meader, F. Xiao, M. Woodward, H. J. M. Brady, R. Lechler, G. Lombardi

Clin Exp Immunol. 2017 May; 188(2): 219–225. Published online 2017 Mar 2. doi: 10.1111/cei.12931

PMCID:: PMC5383447

Abstract Article PDF–302K

Select item 53442138.

Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment

Robyn L Schenk, Selma Tuzlak, Emma M Carrington, Yifan Zhan, Susanne Heinzel, Charis E Teh, Daniel H Gray, Lin Tai, Andrew M Lew, Andreas Villunger, Andreas Strasser, Marco J Herold

Cell Death Differ. 2017 Mar; 24(3): 534–545. Published online 2017 Jan 13. doi: 10.1038/cdd.2016.156

PMCID:: PMC5344213

Abstract Article PDF–3.8M

Select item 53442129.

The BCL-2 pro-survival protein A1 is dispensable for T cell homeostasis on viral infection

Selma Tuzlak, Robyn L Schenk, Ajithkumar Vasanthakumar, Simon P Preston, Manuel D Haschka, Dimitra Zotos, Axel Kallies, Andreas Strasser, Andreas Villunger, Marco J Herold

Cell Death Differ. 2017 Mar; 24(3): 523–533. Published online 2017 Jan 13. doi: 10.1038/cdd.2016.155

PMCID:: PMC5344212

Abstract Article PDF–1.7M

Select item 498663510.

Conditional knockdown of BCL2A1 reveals rate-limiting roles in BCR-dependent B-cell survival

M Sochalska, E Ottina, S Tuzlak, S Herzog, M Herold, A Villunger

Cell Death Differ. 2016 Apr; 23(4): 628–639. Published online 2015 Oct 9. doi: 10.1038/cdd.2015.130

PMCID:: PMC4986635

Abstract Article PDF–4.1M

Select item 497021311.

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA

Xiaoyun Liu, Yan Jiao, Yanhong Cao, Nan Deng, Yonghui Ma, Karen A. Hasty, Andrew Kang, Hong Chen, John M. Stuart, Weikuan Gu

BMC Immunol. 2016; 17: 25. Published online 2016 Aug 2. doi: 10.1186/s12865-016-0163-y

PMCID:: PMC4970213

Abstract Article PDF–2.5M

Select item 495111112.

Selective Impairment of T_H17-Differentiation and Protection against Autoimmune Arthritis after Overexpression of BCL2A1 in T Lymphocytes

Marcos Iglesias, Juan Jesús Augustin, Pilar Alvarez, Inés Santiuste, Jorge Postigo, Jesús Merino, Ramón Merino

PLoS One. 2016; 11(7): e0159714. Published online 2016 Jul 19. doi: 10.1371/journal.pone.0159714

PMCID:: PMC4951111

Abstract Article PDF–2.7M

Select item 456236513.

Lessons from gain- and loss-of-function models of pro-survival Bcl2 family proteins: implications for targeted therapy

Maja Sochalska, Selma Tuzlak, Alexander Egle, Andreas Villunger

FEBS J. Author manuscript; available in PMC 2015 Sep 8.

Published in final edited form as: FEBS J. 2015 Mar; 282(5): 834–849. Published online 2015 Jan 23. doi: 10.1111/febs.13188

PMCID:: PMC4562365

Abstract Article PDF–899K

Select item 429812614.

Knockdown of the Antiapoptotic Bcl-2 Family Member A1/Bfl-1 Protects Mice from Anaphylaxis

Eleonora Ottina, Katarina Lyberg, Maja Sochalska, Andreas Villunger, Gunnar P. Nilsson

J Immunol. 2015 Feb 1; 194(3): 1316–1322. Published online 2014 Dec 29. doi: 10.4049/jimmunol.1400637

PMCID:: PMC4298126

Abstract Article PDF–972K

Select item 348407215.

BCL2A1a Over-Expression in Murine Hematopoietic Stem and Progenitor Cells Decreases Apoptosis and Results in Hematopoietic Transformation

Jean-Yves Métais, Thomas Winkler, Julia T. Geyer, Rodrigo T. Calado, Peter D. Aplan, Michael A. Eckhaus, Cynthia E. Dunbar

PLoS One. 2012; 7(10): e48267. Published online 2012 Oct 30. doi: 10.1371/journal.pone.0048267

PMCID:: PMC3484072

Abstract Article PDF–894K

Select item 341876916.

Targeting antiapoptotic A1/Bfl-1 by in vivo RNAi reveals multiple roles in leukocyte development in mice

Eleonora Ottina, Francesca Grespi, Denise Tischner, Claudia Soratroi, Stephan Geley, Andreas Ploner, Holger M. Reichardt, Andreas Villunger, Marco J. Herold

Blood. 2012 Jun 21; 119(25): 6032–6042. Prepublished online 2012 May 11. doi: 10.1182/blood-2011-12-399089

PMCID:: PMC3418769

Abstract Article

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253418.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 286726619.

Defective ubiquitin-mediated degradation of antiapoptotic Bfl-1 predisposes to lymphoma

Gaofeng Fan, Matthew J. Simmons, Sheng Ge, Jui Dutta-Simmons, Jérôme Kucharczak, Yacov Ron, David Weissmann, Chiann-Chyi Chen, Chandreyee Mukherjee, Eileen White, Céline Gélinas

Blood. 2010 Apr 29; 115(17): 3559–3569. Prepublished online 2010 Feb 25. doi: 10.1182/blood-2009-08-236760

PMCID:: PMC2867266

Abstract Article

Select item 226545120.

NFAT but not NF-κB is critical for transcriptional induction of the prosurvival gene A1 after IgE receptor activation in mast cells

Erik Ullerås, Mats Karlberg, Christine Möller Westerberg, Jessica Alfredsson, Steve Gerondakis, Andreas Strasser, Gunnar Nilsson

Blood. 2008 Mar 15; 111(6): 3081–3089. Prepublished online 2008 Jan 8. doi: 10.1182/blood-2006-10-053371

PMCID:: PMC2265451

Abstract Article

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