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Select item 105768131.

KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors

Bo Zhang, Chen Zhao, Wenchen Shen, Wei Li, Yue Zheng, Xiangfei Kong, Junbao Wang, Xudong Wu, Tao Zeng, Ying Liu, Yan Zhou

Nat Commun. 2023; 14: 6489. Published online 2023 Oct 14. doi: 10.1038/s41467-023-42322-2

PMCID:: PMC10576813

Abstract Article PDF–13M

Select item 104035522.

PRC1 suppresses a female gene regulatory network to ensure testicular differentiation

So Maezawa, Masashi Yukawa, Kazuteru Hasegawa, Ryo Sugiyama, Mizuho Iizuka, Mengwen Hu, Akihiko Sakashita, Miguel Vidal, Haruhiko Koseki, Artem Barski, Tony DeFalco, Satoshi H. Namekawa

Cell Death Dis. 2023 Aug; 14(8): 501. Published online 2023 Aug 4. doi: 10.1038/s41419-023-05996-6

PMCID:: PMC10403552

Abstract Article PDF–3.8M

Select item 103303623.

Polycomb group protein CBX7 represses cardiomyocyte proliferation via modulation of the TARDBP/RBM38 axis

Kyu-Won Cho, Mark Andrade, Seongho Bae, Sangsung Kim, Jin Eyun Kim, Er Yearn Jang, Sangho Lee, Ahsan Husain, Roy L. Sutliff, John W. Calvert, Changwon Park, Young-sup Yoon

Circulation. Author manuscript; available in PMC 2024 Jun 13.

Published in final edited form as: Circulation. 2023 Jun 13; 147(24): 1823–1842. Published online 2023 May 9. doi: 10.1161/CIRCULATIONAHA.122.061131

PMCID:: PMC10330362

Abstract Article PDF–1.6M

Select item 101914414.

USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities

Chao Liu, Lingang Sun, Yijun Tan, Qi Wang, Tao Luo, Chenlu Li, Nan Yao, Yuting Xie, Xiao Yi, Yi Zhu, Tiannan Guo, Junfeng Ji

Sci Adv. 2023 May; 9(20): eade3888. Published online 2023 May 17. doi: 10.1126/sciadv.ade3888

PMCID:: PMC10191441

Abstract Article PDF–2.4M

Select item 97054305.

PCGF1-PRC1 links chromatin repression with DNA replication during hematopoietic cell lineage commitment

Junichiro Takano, Shinsuke Ito, Yixing Dong, Jafar Sharif, Yaeko Nakajima-Takagi, Taichi Umeyama, Yong-Woon Han, Kyoichi Isono, Takashi Kondo, Yusuke Iizuka, Tomohiro Miyai, Yoko Koseki, Mika Ikegaya, Mizuki Sakihara, Manabu Nakayama, Osamu Ohara, Yoshinori Hasegawa, Kosuke Hashimoto, Erik Arner, Robert J. Klose, Atsushi Iwama, Haruhiko Koseki, Tomokatsu Ikawa

Nat Commun. 2022; 13: 7159. Published online 2022 Nov 28. doi: 10.1038/s41467-022-34856-8

PMCID:: PMC9705430

Abstract Article PDF–4.0M

Select item 91780066.

USP16-mediated histone H2A lysine-119 deubiquitination during oocyte maturation is a prerequisite for zygotic genome activation

Yan Rong, Ye-Zhang Zhu, Jia-li Yu, Yun-Wen Wu, Shu-Yan Ji, Yong Zhou, Yu Jiang, Jin Jin, Heng-Yu Fan, Li Shen, Qian-Qian Sha

Nucleic Acids Res. 2022 Jun 10; 50(10): 5599–5616. Published online 2022 May 30. doi: 10.1093/nar/gkac468

PMCID:: PMC9178006

Abstract Article PDF–6.6M

Select item 89891487.

Bmi‐1‐RING1B prevents GATA4‐dependent senescence‐associated pathological cardiac hypertrophy by promoting autophagic degradation of GATA4

Haiyun Chen, Jiawen Zhou, Hongjie Chen, Jialong Liang, Chunfeng Xie, Xin Gu, Rong Wang, Zhiyuan Mao, Yongjie Zhang, Qing Li, Guoping Zuo, Dengshun Miao, Jianliang Jin

Clin Transl Med. 2022 Apr; 12(4): e574. Published online 2022 Apr 7. doi: 10.1002/ctm2.574

Correction in:: Clin Transl Med. 2024 Jul; 14(7): e1748.

PMCID:: PMC8989148

Abstract Article PDF–8.7M

Select item 88095078.

RNF2 ablation reprograms the tumor-immune microenvironment and stimulates durable NK and CD4⁺ T-cell-dependent antitumor immunity

Zhuo Zhang, Lin Luo, Chuan Xing, Yu Chen, Peng Xu, Mao Li, Ling Zeng, Chao Li, Sadashib Ghosh, Deborah Della Manna, Tim Townes, William J. Britt, Narendra Wajapeyee, Barry P. Sleckman, Zechen Chong, Jianmei Wu Leavenworth, Eddy S Yang

Nat Cancer. Author manuscript; available in PMC 2022 Apr 22.

Published in final edited form as: Nat Cancer. 2021 Oct; 2(10): 1018–1038. Published online 2021 Oct 22. doi: 10.1038/s43018-021-00263-z

PMCID:: PMC8809507

Abstract Article PDF–7.2M

Select item 87657559.

PRC1 sustains the integrity of neural fate in the absence of PRC2 function

Ayana Sawai, Sarah Pfennig, Milica Bulajić, Alexander Miller, Alireza Khodadadi-Jamayran, Esteban O Mazzoni, Jeremy S Dasen

eLife. 2022; 11: e72769. Published online 2022 Jan 7. doi: 10.7554/eLife.72769

PMCID:: PMC8765755

Abstract Article PDF–7.5M

Select item 860478410.

NRF1 Association with AUTS2-Polycomb Mediates Specific Gene Activation in the Brain

Sanxiong Liu, Kimberly A. Aldinger, Chi Vicky Cheng, Takae Kiyama, Mitali Dave, Hanna K. McNamara, Wukui Zhao, James M. Stafford, Nicolas Descostes, Pedro Lee, Stefano G. Caraffi, Ivan Ivanovski, Edoardo Errichiello, Christiane Zweier, Orsetta Zuffardi, Michael Schneider, Antigone S. Papavasiliou, M. Scott Perry, Jennifer Humberson, Megan T. Cho, Astrid Weber, Andrew Swale, Tudor C. Badea, Chai-An Mao, Livia Garavelli, William B. Dobyns, Danny Reinberg

Mol Cell. Author manuscript; available in PMC 2022 Nov 18.

Published in final edited form as: Mol Cell. 2021 Nov 18; 81(22): 4663–4676.e8. Published online 2021 Oct 11. doi: 10.1016/j.molcel.2021.09.020

Correction in:: Mol Cell. 2021 Nov 18; 81(22): 4757.

PMCID:: PMC8604784

Abstract Article PDF–2.8M

Select item 852144011.

UV-induced reduction in Polycomb repression promotes epidermal pigmentation

Meng-Yen Li, Pooja Flora, Hong Pu, Carmit Bar, Jose Silva, Idan Cohen, Phillip M. Galbo, Jr., Hequn Liu, Xufen Yu, Jian Jin, Haruhiko Koseki, John A. D’Orazio, Deyou Zheng, Elena Ezhkova

Dev Cell. Author manuscript; available in PMC 2022 Sep 27.

Published in final edited form as: Dev Cell. 2021 Sep 27; 56(18): 2547–2561.e8. Published online 2021 Sep 1. doi: 10.1016/j.devcel.2021.08.006

PMCID:: PMC8521440

Abstract Article PDF–3.7M

Select item 831323912.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 791941213.

Polycomb complexes redundantly maintain epidermal stem cell identity during development

Idan Cohen, Carmit Bar, Hequn Liu, Victor J. Valdes, Dejian Zhao, Phillip M. Galbo, Jr., Jose M. Silva, Haruhiko Koseki, Deyou Zheng, Elena Ezhkova

Genes Dev. 2021 Mar 1; 35(5-6): 354–366. doi: 10.1101/gad.345363.120

PMCID:: PMC7919412

Abstract Article PDF–9.0M

Select item 765835214.

The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon

Hikaru Eto, Yusuke Kishi, Nayuta Yakushiji-Kaminatsui, Hiroki Sugishita, Shun Utsunomiya, Haruhiko Koseki, Yukiko Gotoh

Nat Commun. 2020; 11: 5709. Published online 2020 Nov 11. doi: 10.1038/s41467-020-19556-5

PMCID:: PMC7658352

Abstract Article PDF–4.7M

Select item 761689415.

Polycomb repressive complexes 1 and 2 are each essential for maintenance of X inactivation in extra-embryonic lineages

Osamu Masuil, Catherine Corbel, Koji Nagao, Takaho A. Endo, Fuyuko Kezuka, Patricia Diabangouaya, Manabu Nakayama, Mami Kumon, Yoko Koseki, Chikashi Obuse, Haruhiko Koseki, Edith Heard

Nat Cell Biol. Author manuscript; available in PMC 2024 Dec 5.

Published in final edited form as: Nat Cell Biol. 2023 Jan 1; 25(1): 134–144. Published online 2023 Jan 12. doi: 10.1038/s41556-022-01047-y

PMCID:: PMC7616894

Abstract Article PDF–4.9M

Select item 735502016.

Cell stemness is maintained upon concurrent expression of RB and the mitochondrial ribosomal protein S18-2

Muhammad Mushtaq, Larysa Kovalevska, Suhas Darekar, Alexandra Abramsson, Henrik Zetterberg, Vladimir Kashuba, George Klein, Marie Arsenian-Henriksson, Elena Kashuba

Proc Natl Acad Sci U S A. 2020 Jul 7; 117(27): 15673–15683. Published online 2020 Jun 22. doi: 10.1073/pnas.1922535117