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Items: 1 to 20 of 209

1.
β-Arrestin scaffolds and signaling elements essential for the obestatin/GPR39 system that determine the myogenic program in human myoblast cells
Icía Santos-Zas, Uxía Gurriarán-Rodríguez, Tania Cid-Díaz, Gabriela Figueroa, Jessica González-Sánchez, Mónica Bouzo-Lorenzo, Carlos S. Mosteiro, José Señarís, Felipe F. Casanueva, Xesús Casabiell, Rosalía Gallego, Yolanda Pazos, Vincent Mouly, Jesús P. Camiña
Cell Mol Life Sci. 2016 Feb; 73(3): 617–635. Published online 2015 Jul 27. doi: 10.1007/s00018-015-1994-z
PMCID:
PMC11108386
AbstractArticlePDF–7.1M
2.
A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2–Bispecific Antibody for Combination Cancer Therapy
Amr El Zawily, Frederick S. Vizeacoumar, Renuka Dahiya, Sara L. Banerjee, Kalpana K. Bhanumathy, Hussain Elhasasna, Glinton Hanover, Jessica C. Sharpe, Malkon G. Sanchez, Paul Greidanus, R. Greg Stacey, Kyung-Mee Moon, Ilya Alexandrov, Juha P. Himanen, Dimitar B. Nikolov, Humphrey Fonge, Aaron P. White, Leonard J. Foster, Bingcheng Wang, Behzad M. Toosi, Nicolas Bisson, Tajib A. Mirzabekov, Franco J. Vizeacoumar, Andrew Freywald
Clin Cancer Res. 2023 Jul 14; 29(14): 2686–2701. Published online 2023 Mar 28. doi: 10.1158/1078-0432.CCR-22-2535
PMCID:
PMC10345963
AbstractArticlePDF–13M
3.
β‐arrestin 2 negatively regulates lung cancer progression by inhibiting the TRAF6 signaling axis for NF-κB activation and autophagy induced by TLR3 and TLR4
Ji Young Kim, Ji Hye Shin, Mi-Jeong Kim, Yeeun Kang, Ji Su Lee, Juhee Son, Soo-Kyung Jeong, Daesik Kim, Duk-Hwan Kim, Eunyoung Chun, Ki-Young Lee
Cell Death Dis. 2023 Jul; 14(7): 422. Published online 2023 Jul 13. doi: 10.1038/s41419-023-05945-3
PMCID:
PMC10344878
AbstractArticlePDF–9.3M
4.
Ubiquitination of GRK2 Is Required for the β-Arrestin-Biased Signaling Pathway of Dopamine D2 Receptors to Activate ERK Kinases
Haiping Liu, Haixiang Ma, Xingyue Zeng, Chengyan Wu, Srijan Acharya, Sarabjeet Kour Sudan, Xiaohan Zhang
Int J Mol Sci. 2023 Jun; 24(12): 10031. Published online 2023 Jun 12. doi: 10.3390/ijms241210031
PMCID:
PMC10298151
AbstractArticlePDF–3.5M
5.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
6.
Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs
Filip Mihalič, Leandro Simonetti, Girolamo Giudice, Marie Rubin Sander, Richard Lindqvist, Marie Berit Akpiroro Peters, Caroline Benz, Eszter Kassa, Dilip Badgujar, Raviteja Inturi, Muhammad Ali, Izabella Krystkowiak, Ahmed Sayadi, Eva Andersson, Hanna Aronsson, Ola Söderberg, Doreen Dobritzsch, Evangelia Petsalaki, Anna K. Överby, Per Jemth, Norman E. Davey, Ylva Ivarsson
Nat Commun. 2023; 14: 2409. Published online 2023 Apr 26. doi: 10.1038/s41467-023-38015-5
PMCID:
PMC10132805
AbstractArticlePDF–4.2M
7.
Dysregulated Smooth Muscle Cell BMPR2 – ARRB2 Axis Causes Pulmonary Hypertension
Lingli Wang, Jan Renier Moonen, Aiqin Cao, Sarasa Isobe, Caiyun G Li, Nancy F Tojais, Shalina Taylor, David P Marciano, Pin-I Chen, Mingxia Gu, Dan Li, Rebecca L Harper, Nesrine El-Bizri, YuMee Kim, Kryn Stankunas, Marlene Rabinovitch
Circ Res. Author manuscript; available in PMC 2024 Mar 3.
Published in final edited form as: Circ Res. 2023 Mar 3; 132(5): 545–564. Published online 2023 Feb 6. doi: 10.1161/CIRCRESAHA.121.320541
PMCID:
PMC10008520
AbstractArticlePDF–4.4M
8.
The Comprehensive Analysis of Hub Gene ARRB2 in Prostate Cancer
Bing Zhou, Hong Song, Wuqin Xu, Yanbin Zhang, Yinhua Liu, Wei Qi
Dis Markers. 2022; 2022: 8518378. Published online 2022 Oct 15. doi: 10.1155/2022/8518378
PMCID:
PMC9588343
AbstractArticlePDF–3.7M
9.
SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein
Marius Walter, Irene P. Chen, Albert Vallejo-Gracia, Ik-Jung Kim, Olga Bielska, Victor L. Lam, Jennifer M. Hayashi, Andrew Cruz, Samah Shah, Frank W. Soveg, John D. Gross, Nevan J. Krogan, Keith R. Jerome, Birgit Schilling, Melanie Ott, Eric Verdin
PLoS Pathog. 2022 Sep; 18(9): e1010811. Published online 2022 Sep 12. doi: 10.1371/journal.ppat.1010811
PMCID:
PMC9499238
AbstractArticlePDF–3.7M
10.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
11.
Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome
Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson
Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584
PMCID:
PMC8769072
AbstractArticlePDF–2.9M
12.
Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation
Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley
Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h
PMCID:
PMC8763317
AbstractArticle
13.
Biphasic activation of β-arrestin 1 upon interaction with a GPCR revealed by methyl-TROSY NMR
Yutaro Shiraishi, Yutaka Kofuku, Takumi Ueda, Shubhi Pandey, Hemlata Dwivedi-Agnihotri, Arun K. Shukla, Ichio Shimada
Nat Commun. 2021; 12: 7158. Published online 2021 Dec 9. doi: 10.1038/s41467-021-27482-3
PMCID:
PMC8660791
AbstractArticlePDF–1.7M
14.
β-arrestin 2 stimulates degradation of HIF-1α and modulates tumor progression of glioblastoma
Woom-Yee Bae, Jae-Sun Choi, Seungyoon Nam, Joo-Won Jeong
Cell Death Differ. 2021 Nov; 28(11): 3092–3104. Published online 2021 May 18. doi: 10.1038/s41418-021-00802-2
PMCID:
PMC8563934
AbstractArticlePDF–2.2M
15.
The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation
Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari
PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412
PMCID:
PMC8513853
AbstractArticlePDF–4.1M
16.
Scaffolding mechanism of arrestin-2 in the cRaf/MEK1/ERK signaling cascade
Changxiu Qu, Ji Young Park, Min Woo Yun, Qing-tao He, Fan Yang, Kiae Kim, Donghee Ham, Rui-rui Li, T. M. Iverson, Vsevolod V. Gurevich, Jin-Peng Sun, Ka Young Chung
Proc Natl Acad Sci U S A. 2021 Sep 14; 118(37): e2026491118. Published online 2021 Sep 10. doi: 10.1073/pnas.2026491118
PMCID:
PMC8449410
AbstractArticlePDF–1.6M
17.
Biased Coupling to β-Arrestin of Two Common Variants of the CB2 Cannabinoid Receptor
Gábor Turu, Eszter Soltész-Katona, András Dávid Tóth, Cintia Juhász, Miklós Cserző, Ádám Misák, András Balla, Marc G. Caron, László Hunyady
Front Endocrinol (Lausanne) 2021; 12: 714561. Published online 2021 Aug 16. doi: 10.3389/fendo.2021.714561
PMCID:
PMC8415483
AbstractArticlePDF–6.7M
18.
β-arrestin2 (ARRB2) Polymorphism Associated with the Adverse Consequences of Chronic Heroin Use
Klevis K. Karavidha, Margit Burmeister, Mark K. Greenwald
Am J Addict. Author manuscript; available in PMC 2022 Jul 1.
Published in final edited form as: Am J Addict. 2021 Jul; 30(4): 351–357. Published online 2021 Mar 30. doi: 10.1111/ajad.13150
PMCID:
PMC8243774
AbstractArticlePDF–548K
19.
ACE2 interaction with cytoplasmic PDZ protein enhances SARS-CoV-2 invasion
Qiangmin Zhang, Julia Gefter, W. Bruce Sneddon, Tatyana Mamonova, Peter A. Friedman
iScience. 2021 Jul 23; 24(7): 102770. Published online 2021 Jun 24. doi: 10.1016/j.isci.2021.102770
PMCID:
PMC8223119
AbstractArticlePDF–3.0M
20.
Structural insights into the human D1 and D2 dopamine receptor signaling complexes
Youwen Zhuang, Peiyu Xu, Chunyou Mao, Lei Wang, Brian Krumm, X. Edward Zhou, Sijie Huang, Heng Liu, Xi Cheng, Xi-Ping Huang, Dan-Dan Shen, Tinghai Xu, Yong-Feng Liu, Yue Wang, Jia Guo, Yi Jiang, Hualiang Jiang, Karsten Melcher, Bryan L. Roth, Yan Zhang, Cheng Zhang, H. Eric Xu
Cell. Author manuscript; available in PMC 2021 Jun 21.
Published in final edited form as: Cell. 2021 Feb 18; 184(4): 931–942.e18. Published online 2021 Feb 10. doi: 10.1016/j.cell.2021.01.027
PMCID:
PMC8215686
AbstractArticlePDF–3.1M

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