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Select item 107838461.

miRNA-660-3p inhibits malignancy in glioblastoma via negative regulation of APOC1-TGFβ2 signaling pathway

Zelin Yang, Liang Yang, Zhenkai Sun, Yuxi Rong, Chenglian Bai, Qiaoxiang Dong, Lin Jian

Cancer Biol Ther. 2023; 24(1): 2281459. Published online 2023 Nov 19. doi: 10.1080/15384047.2023.2281459

PMCID:: PMC10783846

Abstract Article PDF–5.2M

Select item 107061482.

The Research Progress in Transforming Growth Factor-β2

Meng-Yan Wang, Wen-Juan Liu, Le-Yi Wu, Gang Wang, Cheng-Lin Zhang, Jie Liu

Cells. 2023 Dec; 12(23): 2739. Published online 2023 Nov 30. doi: 10.3390/cells12232739

PMCID:: PMC10706148

Abstract Article PDF–3.8M

Select item 106629723.

Myocardial equation M1

-Catenin-BMP2 signaling promotes mesenchymal cell proliferation during endocardial cushion formation

Yidong Wang, Pengfei Lu, Bingruo Wu, Dario F. Riascos-Bernal, Nicholas E.S. Sibinga, Tomas Valenta, Konrad Basler, Bin Zhou

J Mol Cell Cardiol. Author manuscript; available in PMC 2023 Nov 21.

Published in final edited form as: J Mol Cell Cardiol. 2018 Oct; 123: 150–158. Published online 2018 Sep 8. doi: 10.1016/j.yjmcc.2018.09.001

PMCID:: PMC10662972

Abstract Article PDF–2.2M

Select item 106559184.

The transcription factors Foxf1 and Foxf2 integrate the SHH, HGF and TGFβ signaling pathways to drive tongue organogenesis

Jingyue Xu, Han Liu, Yu Lan, Rulang Jiang

Development. 2022 Nov 1; 149(21): dev200667. Published online 2022 Oct 28. doi: 10.1242/dev.200667

PMCID:: PMC10655918

Abstract Article

Select item 105277635.

TGFβ−2 haploinsufficiency causes early death in mice with Marfan syndrome

Nalani Sachan, Colin K.L. Phoon, Lior Zilberberg, Matthias C. Kugler, Taylor Ene, Shana B. Mintz, Sae-Il Murtada, Dar Weiss, Glenn I. Fishman, Jay D. Humphrey, Daniel B. Rifkin

Matrix Biol. Author manuscript; available in PMC 2023 Sep 27.

Published in final edited form as: Matrix Biol. 2023 Aug; 121: 41–55. Published online 2023 May 20. doi: 10.1016/j.matbio.2023.05.004

PMCID:: PMC10527763

Abstract Article PDF–1.6M

Select item 104107536.

Elevated TGFβ signaling contributes to ocular anterior segment dysgenesis in Col4a1 mutant mice

Mao Mao, Cassandre Labelle-Dumais, Sara F. Tufa, Douglas R. Keene, Douglas B. Gould

Matrix Biol. Author manuscript; available in PMC 2023 Aug 9.

Published in final edited form as: Matrix Biol. 2022 Jun; 110: 151–173. Published online 2022 May 4. doi: 10.1016/j.matbio.2022.05.001

PMCID:: PMC10410753

Abstract Article PDF–2.2M

Select item 102595147.

Dysfunction of programmed embryo senescence is linked to genetic developmental defects

Cristina de Lope, Rebeca García-Lucena, Marta Magariños, Yolanda León, Nuria Casa-Rodríguez, Nuria Contreras, Carmen Escudero-Iriarte, Isabel Varela-Nieto, Pascal Maire, Ignacio Palmero

Development. 2023 May 1; 150(9): dev200903. Published online 2023 May 3. doi: 10.1242/dev.200903

PMCID:: PMC10259514

Abstract Article

Select item 101104238.

Sp3 is essential for normal lung morphogenesis and cell cycle progression during mouse embryonic development

Alyssa M. McCoy, Omar Lakhdari, Sayane Shome, Kaitlin Caoili, Gilberto E. Hernandez, Nima Aghaeepour, Lindsay D. Butcher, Kathleen Fisch, Lawrence S. Prince

Development. 2023 Mar 1; 150(5): dev200839. Published online 2023 Mar 3. doi: 10.1242/dev.200839

PMCID:: PMC10110423

Abstract Article

Select item 98723219.

Neonatal inflammation increases hippocampal KCC2 expression through methylation-mediated TGF-β1 downregulation leading to impaired hippocampal cognitive function and synaptic plasticity in adult mice

Jing Rong, Yang Yang, Min Liang, Haiquan Zhong, Yingchun Li, Yichao Zhu, Sha Sha, Lei Chen, Rong Zhou

J Neuroinflammation. 2023; 20: 15. Published online 2023 Jan 23. doi: 10.1186/s12974-023-02697-x

PMCID:: PMC9872321

Abstract Article PDF–5.6M

Select item 977234610.

SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouse

Aya Uchida, Kenya Imaimatsu, Honoka Suzuki, Xiao Han, Hiroki Ushioda, Mami Uemura, Kasane Imura-Kishi, Ryuji Hiramatsu, Hinako M. Takase, Yoshikazu Hirate, Atsuo Ogura, Masami Kanai-Azuma, Akihiko Kudo, Yoshiakira Kanai

Nat Commun. 2022; 13: 7860. Published online 2022 Dec 21. doi: 10.1038/s41467-022-35465-1

PMCID:: PMC9772346

Abstract Article PDF–15M

Select item 973996711.

TGF-β2 Regulates Transcription of the K⁺/Cl⁻ Cotransporter 2 (KCC2) in Immature Neurons and Its Phosphorylation at T1007 in Differentiated Neurons

Anastasia Rigkou, Attila Magyar, Jan Manuel Speer, Eleni Roussa

Cells. 2022 Dec; 11(23): 3861. Published online 2022 Nov 30. doi: 10.3390/cells11233861

PMCID:: PMC9739967

Abstract Article PDF–3.4M

Select item 971371612.

Maternal immune activation leads to defective brain–blood vessels and intracerebral hemorrhages in male offspring

Marco Rasile, Eliana Lauranzano, Elisa Faggiani, Margherita M Ravanelli, Federico S Colombo, Filippo Mirabella, Irene Corradini, Maria L Malosio, Antonella Borreca, Elisa Focchi, Davide Pozzi, Toni Giorgino, Isabella Barajon, Michela Matteoli

EMBO J. 2022 Dec; 41(23): e111192. Published online 2022 Oct 31. doi: 10.15252/embj.2022111192

Correction in:: EMBO J. 2023 May; 42(10): e113890.

PMCID:: PMC9713716

Abstract Article PDF–3.2M

Select item 962426213.

Endothelial loss of ETS1 impairs coronary vascular development and leads to ventricular non-compaction

Lu Wang, Lizhu Lin, Hui Qi, Ju Chen, Paul Grossfeld

Circ Res. Author manuscript; available in PMC 2023 Aug 19.

Published in final edited form as: Circ Res. 2022 Aug 19; 131(5): 371–387. Published online 2022 Jul 27. doi: 10.1161/CIRCRESAHA.121.319955

PMCID:: PMC9624262

Abstract Article PDF–4.5M

Select item 898800814.

Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia

Ann-Helen Rosendahl, Mia Monnius, Anu Laitala, Antti Railo, Ilkka Miinalainen, Ritva Heljasvaara, Joni M. Mäki, Johanna Myllyharju

J Biol Chem. 2022 Apr; 298(4): 101787. Published online 2022 Mar 2. doi: 10.1016/j.jbc.2022.101787

PMCID:: PMC8988008

Abstract Article PDF–6.1M

Select item 891454815.

TFPI2 suppresses the interaction of TGF-β2 pathway regulators to promote endothelial–mesenchymal transition in diabetic nephropathy

Guoying Guan, Jinjiao Xie, Yamei Dai, Hui Han

J Biol Chem. 2022 Mar; 298(3): 101725. Published online 2022 Feb 11. doi: 10.1016/j.jbc.2022.101725

PMCID:: PMC8914548

Abstract Article PDF–7.7M

Select item 876711116.

TGFβ2 Induces the Soluble Isoform of CTLA-4 – Implications for CTLA-4 Based Checkpoint Inhibitor Antibodies in Malignant Melanoma

Rahul C. Khanolkar, Chu Zhang, Farah Al-Fatyan, Linda Lawson, Ivan Depasquale, Fiona M. Meredith, Frank Muller, Marianne Nicolson, Lekh Nath Dahal, Rasha Abu-Eid, Sanjay Rajpara, Robert Norman Barker, Anthony D. Ormerod, Frank James Ward

Front Immunol. 2021; 12: 763877. Published online 2022 Jan 5. doi: 10.3389/fimmu.2021.763877

PMCID:: PMC8767111

Abstract Article PDF–15M

Select item 861972717.

Astragaloside IV Attenuates Ocular Hypertension in a Mouse Model of TGFβ2 Induced Primary Open Angle Glaucoma

Ramesh B. Kasetti, Prabhavathi Maddineni, Bindu Kodati, Bhavani Nagarajan, Sam Yacoub

Int J Mol Sci. 2021 Nov; 22(22): 12508. Published online 2021 Nov 19. doi: 10.3390/ijms222212508

PMCID:: PMC8619727

Abstract Article PDF–3.0M

Select item 858141618.

hnRNPU in Sertoli cells cooperates with WT1 and is essential for testicular development by modulating transcriptional factors Sox8/9

Yujiao Wen, Xixiang Ma, Xiaoli Wang, Fengli Wang, Juan Dong, Yanqing Wu, Chunyu Lv, Kuan Liu, Yan Zhang, Zhibing Zhang, Shuiqiao Yuan

Theranostics. 2021; 11(20): 10030–10046. Published online 2021 Oct 25. doi: 10.7150/thno.66819

PMCID:: PMC8581416

Abstract Article PDF–3.5M

Select item 848249919.

Splicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium

Xiaoli Zhang, Ze Wang, Qing Xu, Yuhan Chen, Wen Liu, Tong Zhong, Hongchang Li, Chengshi Quan, Lingqiang Zhang, Chun-Ping Cui

iScience. 2021 Oct 22; 24(10): 103097. Published online 2021 Sep 10. doi: 10.1016/j.isci.2021.103097

PMCID:: PMC8482499

Abstract Article PDF–5.1M

Select item 841187720.

Oligodendrocyte precursor cell specification is regulated by bidirectional neural progenitor–endothelial cell crosstalk

Isidora Paredes, José Ricardo Vieira, Bhavin Shah, Carla F. Ramunno, Julia Dyckow, Heike Adler, Melanie Richter, Geza Schermann, Evangelia Giannakouri, Lucas Schirmer, Hellmut G. Augustin, Carmen Ruiz de Almodóvar

Nat Neurosci. Author manuscript; available in PMC 2021 Sep 2.

Published in final edited form as: Nat Neurosci. 2021 Apr; 24(4): 478–488. Published online 2021 Jan 28. doi: 10.1038/s41593-020-00788-z