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Items: 1 to 20 of 328

1.
Follistatin controls the number of murine teeth by limiting TGF-β signaling
Shicheng Zhu, Suman Huo, Zhongzheng Wang, Caiyan Huang, Chuanxu Li, Hanjing Song, Xueqin Yang, Rui He, Cheng Ding, Mengsheng Qiu, Xiao-Jing Zhu
iScience. 2024 Sep 20; 27(9): 110785. Published online 2024 Aug 22. doi: 10.1016/j.isci.2024.110785
PMCID:
PMC11403059
AbstractArticlePDF–5.0M
2.
Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner
Davy Vanhoutte, Tobias G. Schips, Rachel A. Minerath, Jiuzhou Huo, Naga Swathi Sree Kavuri, Vikram Prasad, Suh-Chin Lin, Michael J. Bround, Michelle A. Sargent, Christopher M. Adams, Jeffery D. Molkentin
Cell Rep. Author manuscript; available in PMC 2024 Jul 2.
Published in final edited form as: Cell Rep. 2024 May 28; 43(5): 114149. Published online 2024 Apr 26. doi: 10.1016/j.celrep.2024.114149
PMCID:
PMC11217783
AbstractArticlePDF–3.2M
3.
The chromatin regulator Ankrd11 controls cardiac neural crest cell-mediated outflow tract remodeling and heart function
Yana Kibalnyk, Elia Afanasiev, Ronan M. N. Noble, Adrianne E. S. Watson, Irina Poverennaya, Nicole L. Dittmann, Maria Alexiou, Kara Goodkey, Amanda A. Greenwell, John R. Ussher, Igor Adameyko, James Massey, Daniel Graf, Stephane L. Bourque, Jo Anne Stratton, Anastassia Voronova
Nat Commun. 2024; 15: 4632. Published online 2024 Jul 1. doi: 10.1038/s41467-024-48955-1
PMCID:
PMC11217281
AbstractArticlePDF–6.8M
4.
APOE4 impairs the microglial response in Alzheimer’s disease by inducing TGFβ-mediated checkpoints
Zhuoran Yin, Neta Rosenzweig, Kilian L. Kleemann, Xiaoming Zhang, Wesley Brandão, Milica A. Margeta, Caitlin Schroeder, Kisha N. Sivanathan, Sebastian Silveira, Christian Gauthier, Dania Mallah, Kristen M. Pitts, Ana Durao, Shawn Herron, Hannah Shorey, Yiran Cheng, Jen-Li Barry, Rajesh K. Krishnan, Sam Wakelin, Jared Rhee, Anthony Yung, Michael Aronchik, Chao Wang, Nimansha Jain, Xin Bao, Emma Gerrits, Nieske Brouwer, Amy Deik, Daniel G. Tenen, Tsuneya Ikezu, Nicolas G. Santander, Gabriel L. McKinsey, Caroline Baufeld, Dean Sheppard, Susanne Krasemann, Roni Nowarski, Bart J.L. Eggen, Clary Clish, Rudolph E. Tanzi, Charlotte Madore, Thomas D. Arnold, David M. Holtzman, Oleg Butovsky
Nat Immunol. Author manuscript; available in PMC 2024 Nov 1.
Published in final edited form as: Nat Immunol. 2023 Nov; 24(11): 1839–1853. Published online 2023 Sep 25. doi: 10.1038/s41590-023-01627-6
PMCID:
PMC10863749
AbstractArticlePDF–8.5M
5.
The transcription factors Foxf1 and Foxf2 integrate the SHH, HGF and TGFβ signaling pathways to drive tongue organogenesis
Jingyue Xu, Han Liu, Yu Lan, Rulang Jiang
Development. 2022 Nov 1; 149(21): dev200667. Published online 2022 Oct 28. doi: 10.1242/dev.200667
PMCID:
PMC10655918
AbstractArticle
6.
Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure
Ouzna Dali, Shereen D’Cruz, Louis Legoff, Mariam Diba Lahmidi, Celine Heitz, Pierre-Etienne Merret, Pierre-Yves Kernanec, Farzad Pakdel, Fatima Smagulova
Life Sci Alliance. 2024 Feb; 7(2): e202302237. Published online 2023 Nov 16. doi: 10.26508/lsa.202302237
PMCID:
PMC10654101
AbstractArticlePDF–3.1M
7.
The projection-specific signals that establish functionally segregated dopaminergic synapses
Akiko Terauchi, Patricia Yee, Erin M. Johnson-Venkatesh, Mariel P. Seiglie, Lisa Kim, Julia C. Pitino, Eli Kritzer, Qiyu Zhang, Jie Zhou, Yulong Li, David D. Ginty, Wei-Chung A. Lee, Hisashi Umemori
Cell. Author manuscript; available in PMC 2024 Aug 31.
Published in final edited form as: Cell. 2023 Aug 31; 186(18): 3845–3861.e24. Published online 2023 Aug 16. doi: 10.1016/j.cell.2023.07.023
PMCID:
PMC10540635
AbstractArticlePDF–5.1M
8.
Topologically associating domain boundaries are required for normal genome function
Sudha Rajderkar, Iros Barozzi, Yiwen Zhu, Rong Hu, Yanxiao Zhang, Bin Li, Ana Alcaina Caro, Yoko Fukuda-Yuzawa, Guy Kelman, Adyam Akeza, Matthew J. Blow, Quan Pham, Anne N. Harrington, Janeth Godoy, Eman M. Meky, Kianna von Maydell, Riana D. Hunter, Jennifer A. Akiyama, Catherine S. Novak, Ingrid Plajzer-Frick, Veena Afzal, Stella Tran, Javier Lopez-Rios, Michael E. Talkowski, K. C. Kent Lloyd, Bing Ren, Diane E. Dickel, Axel Visel, Len A. Pennacchio
Commun Biol. 2023; 6: 435. Published online 2023 Apr 20. doi: 10.1038/s42003-023-04819-w
PMCID:
PMC10119121
AbstractArticlePDF–3.2M
9.
Specialized endothelial tip cells guide neuroretina vascularization and blood-retina-barrier formation
Georgia Zarkada, Joel P. Howard, Xue Xiao, Hyojin Park, Mathilde Bizou, Severine Leclerc, Steffen E. Künzel, Blanche Boisseau, Jinyu Li, Gael Cagnone, Jean Sebastien Joyal, Gregor Andelfinger, Anne Eichmann, Alexandre Dubrac
Dev Cell. Author manuscript; available in PMC 2023 Feb 24.
Published in final edited form as: Dev Cell. 2021 Aug 9; 56(15): 2237–2251.e6. Published online 2021 Jul 16. doi: 10.1016/j.devcel.2021.06.021
PMCID:
PMC9951594
AbstractArticlePDF–3.9M
10.
ZEB2 controls kidney stromal progenitor differentiation and inhibits abnormal myofibroblast expansion and kidney fibrosis
Sudhir Kumar, Xueping Fan, Hila Milo Rasouly, Richa Sharma, David J. Salant, Weining Lu
JCI Insight. 2023 Jan 10; 8(1): e158418. Published online 2023 Jan 10. doi: 10.1172/jci.insight.158418
PMCID:
PMC9870089
AbstractArticlePDF–8.1M
11.
TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development
Jifan Feng, Xia Han, Yuan Yuan, Courtney Kyeong Cho, Eva Janečková, Tingwei Guo, Siddhika Pareek, Md Shaifur Rahman, Banghong Zheng, Jing Bi, Junjun Jing, Mingyi Zhang, Jian Xu, Thach-Vu Ho, Yang Chai
eLife. 2022; 11: e80405. Published online 2022 Dec 21. doi: 10.7554/eLife.80405
PMCID:
PMC9771365
AbstractArticlePDF–17M
12.
Mitochondrial dysfunction induces ALK5-SMAD2-mediated hypovascularization and arteriovenous malformations in mouse retinas
Haifeng Zhang, Busu Li, Qunhua Huang, Francesc López-Giráldez, Yoshiaki Tanaka, Qun Lin, Sameet Mehta, Guilin Wang, Morven Graham, Xinran Liu, In-Hyun Park, Anne Eichmann, Wang Min, Jenny Huanjiao Zhou
Nat Commun. 2022; 13: 7637. Published online 2022 Dec 10. doi: 10.1038/s41467-022-35262-w
PMCID:
PMC9741628
AbstractArticlePDF–16M
13.
Maternal immune activation leads to defective brain–blood vessels and intracerebral hemorrhages in male offspring
Marco Rasile, Eliana Lauranzano, Elisa Faggiani, Margherita M Ravanelli, Federico S Colombo, Filippo Mirabella, Irene Corradini, Maria L Malosio, Antonella Borreca, Elisa Focchi, Davide Pozzi, Toni Giorgino, Isabella Barajon, Michela Matteoli
EMBO J. 2022 Dec; 41(23): e111192. Published online 2022 Oct 31. doi: 10.15252/embj.2022111192
Correction in:
EMBO J. 2023 May; 42(10): e113890.
PMCID:
PMC9713716
AbstractArticlePDF–3.2M
14.
Creb5 coordinates synovial joint formation with the genesis of articular cartilage
Cheng-Hai Zhang, Yao Gao, Han-Hwa Hung, Zhu Zhuo, Alan J. Grodzinsky, Andrew B. Lassar
Nat Commun. 2022; 13: 7295. Published online 2022 Nov 26. doi: 10.1038/s41467-022-35010-0
PMCID:
PMC9701237
AbstractArticlePDF–10M
15.
Endothelial loss of ETS1 impairs coronary vascular development and leads to ventricular non-compaction
Lu Wang, Lizhu Lin, Hui Qi, Ju Chen, Paul Grossfeld
Circ Res. Author manuscript; available in PMC 2023 Aug 19.
Published in final edited form as: Circ Res. 2022 Aug 19; 131(5): 371–387. Published online 2022 Jul 27. doi: 10.1161/CIRCRESAHA.121.319955
PMCID:
PMC9624262
AbstractArticlePDF–4.5M
16.
O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development
Sanjiv Neupane, Steven J. Berardinelli, Daniel C. Cameron, Richard C. Grady, David E. Komatsu, Christopher J. Percival, Megumi Takeuchi, Atsuko Ito, Ta-Wei Liu, Alison V. Nairn, Kelley W. Moremen, Robert S. Haltiwanger, Bernadette C. Holdener
Matrix Biol. Author manuscript; available in PMC 2022 Oct 27.
Published in final edited form as: Matrix Biol. 2022 Mar; 107: 77–96. Published online 2022 Feb 12. doi: 10.1016/j.matbio.2022.02.002
PMCID:
PMC9606722
AbstractArticlePDF–6.7M
17.
Lack of extracellular matrix switches TGF-β induced apoptosis of endometrial cells to epithelial to mesenchymal transition
Anna Ruiz-Mitjana, Raúl Navaridas, Maria Vidal-Sabanés, Aida Perramon-Güell, Andree Yeramian, Isidre Felip, Núria Eritja, Joaquim Egea, Mario Encinas, Xavier Matias-Guiu, Xavier Dolcet
Sci Rep. 2022; 12: 14821. Published online 2022 Sep 1. doi: 10.1038/s41598-022-18976-1
PMCID:
PMC9437059
AbstractArticlePDF–7.1M
18.
SMAD4, activated by the TCR-triggered MEK/ERK signaling pathway, critically regulates CD8+ T cell cytotoxic function
Xinwei Liu, Jing Hao, Peng Wei, Xiaohong Zhao, Qiuyan Lan, Lu Ni, Yongzhen Chen, Xue Bai, Ling Ni, Chen Dong
Sci Adv. 2022 Jul; 8(30): eabo4577. Published online 2022 Jul 27. doi: 10.1126/sciadv.abo4577
PMCID:
PMC9328680
AbstractArticlePDF–3.4M
19.
Bcar1/p130Cas is essential for ventricular development and neural crest cell remodelling of the cardiac outflow tract
Marwa Mahmoud, Ian Evans, Laura Wisniewski, Yuen Tam, Claire Walsh, Simon Walker-Samuel, Paul Frankel, Peter Scambler, Ian Zachary
Cardiovasc Res. 2022 May; 118(8): 1993–2005. Published online 2021 Jul 16. doi: 10.1093/cvr/cvab242
PMCID:
PMC9239580
AbstractArticlePDF–1.9M
20.
Snrpb is required in murine neural crest cells for proper splicing and craniofacial morphogenesis
Sabrina Shameen Alam, Shruti Kumar, Marie-Claude Beauchamp, Eric Bareke, Alexia Boucher, Nadine Nzirorera, Yanchen Dong, Reinnier Padilla, Si Jing Zhang, Jacek Majewski, Loydie A. Jerome-Majewska
Dis Model Mech. 2022 Jun 1; 15(6): dmm049544. Published online 2022 Jun 23. doi: 10.1242/dmm.049544
PMCID:
PMC9235875
AbstractArticle

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