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Select item 107178761.

Differential gene expression of muscle-specific ubiquitin ligase MAFbx/Atrogin-1 and MuRF1 in response to immobilization-induced atrophy of slow-twitch and fast-twitch muscles

Takeshi Okamoto, Suguru Torii, Shuichi Machida

J Physiol Sci. 2011 Nov; 61(6): 537. Published online 2011 Sep 8. doi: 10.1007/s12576-011-0175-6

PMCID:: PMC10717876

Abstract Article PDF–1.7M

Select item 101830332.

Blocking muscle wasting via deletion of the muscle-specific E3 ligase MuRF1 impedes pancreatic tumor growth

Daria Neyroud, Orlando Laitano, Aneesha Dasgupta, Christopher Lopez, Rebecca E. Schmitt, Jessica Z. Schneider, David W. Hammers, H. Lee Sweeney, Glenn A. Walter, Jason Doles, Sarah M. Judge, Andrew R. Judge

Commun Biol. 2023; 6: 519. Published online 2023 May 13. doi: 10.1038/s42003-023-04902-2

PMCID:: PMC10183033

Abstract Article PDF–5.3M

Select item 93318203.

Removal of MuRF1 Increases Muscle Mass in Nemaline Myopathy Models, but Does Not Provide Functional Benefits

Johan Lindqvist, Justin Kolb, Josine de Winter, Paola Tonino, Zaynab Hourani, Siegfried Labeit, Coen Ottenheijm, Henk Granzier

Int J Mol Sci. 2022 Aug; 23(15): 8113. Published online 2022 Jul 23. doi: 10.3390/ijms23158113

PMCID:: PMC9331820

Abstract Article PDF–3.1M

Select item 92074134.

The Effects of Maternal Intake of EPA and DHA Enriched Diet During Pregnancy and Lactation on Offspring’s Muscle Development and Energy Homeostasis

Saeed Ghnaimawi, Shilei Zhang, Jamie I. Baum, Yan Huang

Front Physiol. 2022; 13: 881624. Published online 2022 Jun 6. doi: 10.3389/fphys.2022.881624

PMCID:: PMC9207413

Abstract Article PDF–6.0M

Select item 91784005.

Targeting MuRF1 by small molecules in a HFpEF rat model improves myocardial diastolic function and skeletal muscle contractility

Volker Adams, Antje Schauer, Antje Augstein, Virginia Kirchhoff, Runa Draskowski, Anett Jannasch, Keita Goto, Gemma Lyall, Anita Männel, Peggy Barthel, Norman Mangner, Ephraim B. Winzer, Axel Linke, Siegfried Labeit

J Cachexia Sarcopenia Muscle. 2022 Jun; 13(3): 1565–1581. Published online 2022 Mar 17. doi: 10.1002/jcsm.12968

PMCID:: PMC9178400

Abstract Article PDF–3.5M

Select item 82180976.

Identification of the MuRF1 Skeletal Muscle Ubiquitylome Through Quantitative Proteomics

Leslie M Baehr, David C Hughes, Sarah A Lynch, Delphi Van Haver, Teresa Mendes Maia, Andrea G Marshall, Lilliana Radoshevich, Francis Impens, David S Waddell, Sue C Bodine

Function (Oxf) 2021; 2(4): zqab029. Published online 2021 May 19. doi: 10.1093/function/zqab029

PMCID:: PMC8218097

Abstract Article PDF–6.4M

Select item 79267067.

Regulation of Glucose Metabolism by MuRF1 and Treatment of Myopathy in Diabetic Mice with Small Molecules Targeting MuRF1

Siegfried Labeit, Stephanie Hirner, Julijus Bogomolovas, André Cruz, Moldir Myrzabekova, Anselmo Moriscot, Thomas Scott Bowen, Volker Adams

Int J Mol Sci. 2021 Feb; 22(4): 2225. Published online 2021 Feb 23. doi: 10.3390/ijms22042225

PMCID:: PMC7926706

Abstract Article PDF–14M

Select item 71847018.

Expression of MuRF1 or MuRF2 is essential for the induction of skeletal muscle atrophy and dysfunction in a murine pulmonary hypertension model

Thanh Nguyen, T. Scott Bowen, Antje Augstein, Antje Schauer, Alexander Gasch, Axel Linke, Siegfried Labeit, Volker Adams

Skelet Muscle. 2020; 10: 12. Published online 2020 Apr 27. doi: 10.1186/s13395-020-00229-2

PMCID:: PMC7184701

Abstract Article PDF–1.1M

Select item 71575859.

Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development

Megha Agarwal, Akashi Sharma, Pankaj Kumar, Amit Kumar, Anushree Bharadwaj, Masum Saini, Gabrielle Kardon, Sam J. Mathew

Development. 2020 Apr 1; 147(7): dev184507. Published online 2020 Apr 6. doi: 10.1242/dev.184507

PMCID:: PMC7157585

Abstract Article

Select item 659904610.

Skeletal muscle in MuRF1 null mice is not spared in low-gravity conditions, indicating atrophy proceeds by unique mechanisms in space

Samuel M. Cadena, Yunyu Zhang, Jian Fang, Sophie Brachat, Pia Kuss, Elisa Giorgetti, Louis S. Stodieck, Michaela Kneissel, David J. Glass

Sci Rep. 2019; 9: 9397. Published online 2019 Jun 28. doi: 10.1038/s41598-019-45821-9

PMCID:: PMC6599046

Abstract Article PDF–2.2M

Select item 628769511.

Autophagy controls neonatal myogenesis by regulating the GH-IGF1 system through a NFE2L2- and DDIT3-mediated mechanism

Silvia Zecchini, Matteo Giovarelli, Cristiana Perrotta, Federica Morisi, Thierry Touvier, Ilaria Di Renzo, Claudia Moscheni, Maria Teresa Bassi, Davide Cervia, Marco Sandri, Emilio Clementi, Clara De Palma

Autophagy. 2019; 15(1): 58–77. Published online 2018 Sep 10. doi: 10.1080/15548627.2018.1507439

PMCID:: PMC6287695

Abstract Article PDF–4.3M

Select item 615097312.

Muscle-specific regulation of right ventricular transcriptional responses to chronic hypoxia-induced hypertrophy by the muscle ring finger-1 (MuRF1) ubiquitin ligase in mice

Robert H. Oakley, Matthew J. Campen, Michael L. Paffett, Xin Chen, Zhongjing Wang, Traci L. Parry, Carolyn Hillhouse, John A. Cidlowski, Monte S. Willis

BMC Med Genet. 2018; 19: 175. Published online 2018 Sep 21. doi: 10.1186/s12881-018-0670-1

PMCID:: PMC6150973

Abstract Article PDF–4.2M

Select item 607556313.

Lamina-associated polypeptide 1 is dispensable for embryonic myogenesis but required for postnatal skeletal muscle growth

Ji-Yeon Shin, Iván Méndez-López, Mingi Hong, Yuexia Wang, Kurenai Tanji, Wei Wu, Leana Shugol, Robert S. Krauss, William T. Dauer, Howard J. Worman

Hum Mol Genet. 2017 Jan 1; 26(1): 65–78. Published online 2016 Oct 25. doi: 10.1093/hmg/ddw368

PMCID:: PMC6075563

Abstract Article PDF–1.1M

Select item 569114214.

Excessive glucocorticoid-induced muscle MuRF1 overexpression is independent of Akt/FoXO1 pathway

Xiao Juan Wang, Jing Jing Xiao, Lei Liu, Hong Chao Jiao, Hai Lin

Biosci Rep. 2017 Dec 22; 37(6): BSR20171056. Prepublished online 2017 Oct 17. Published online 2017 Nov 17. doi: 10.1042/BSR20171056

PMCID:: PMC5691142

Abstract Article PDF–956K

Select item 562280015.

Oligonol, a Low-Molecular Weight Polyphenol Derived from Lychee, Alleviates Muscle Loss in Diabetes by Suppressing Atrogin-1 and MuRF1

Hung-Wen Liu, Yen-Ju Chen, Yun-Ching Chang, Sue-Joan Chang

Nutrients. 2017 Sep; 9(9): 1040. Published online 2017 Sep 20. doi: 10.3390/nu9091040

PMCID:: PMC5622800

Abstract Article PDF–2.9M

Select item 558375716.

Mice overexpressing growth hormone exhibit increased skeletal muscle myostatin and MuRF1 with attenuation of muscle mass

Leslie A. Consitt, Alicson Saneda, Gunjan Saxena, Edward O. List, John J. Kopchick

Skelet Muscle. 2017; 7: 17. Published online 2017 Sep 4. doi: 10.1186/s13395-017-0133-y

PMCID:: PMC5583757

Abstract Article PDF–1.6M

Select item 545366917.

MuRF1 mono-ubiquitinates TRα to inhibit T3-induced cardiac hypertrophy in vivo

Kristine M Wadosky, Jessica M Berthiaume, Wei Tang, Makhosi Zungu, Michael A Portman, A Martin Gerdes, Monte S Willis

J Mol Endocrinol. Author manuscript; available in PMC 2017 Jun 1.

Published in final edited form as: J Mol Endocrinol. 2016 Apr; 56(3): 273–290. Published online 2016 Feb 9. doi: 10.1530/JME-15-0283

PMCID:: PMC5453669

Abstract Article PDF–2.4M

Select item 541492818.

Myostatin Augments Muscle-Specific Ring Finger Protein-1 Expression Through an NF-kB Independent Mechanism in SMAD3 Null Muscle

Sandhya Sriram, Subha Subramanian, Prasanna Kumar Juvvuna, Xiaojia Ge, Sudarsanareddy Lokireddy, Craig Desmond McFarlane, Walter Wahli, Ravi Kambadur, Mridula Sharma

Mol Endocrinol. 2014 Mar; 28(3): 317–330. Published online 2014 Jan 17. doi: 10.1210/me.2013-1179

Correction in:: Mol Endocrinol. 2016 Feb; 30(2): 272–273.

PMCID:: PMC5414928

Abstract Article

Select item 529570619.

Nur77 deletion impairs muscle growth during developmental myogenesis and muscle regeneration in mice

Omar Cortez-Toledo, Caitlin Schnair, Peer Sangngern, Daniel Metzger, Lily C. Chao

PLoS One. 2017; 12(2): e0171268. Published online 2017 Feb 7. doi: 10.1371/journal.pone.0171268

PMCID:: PMC5295706

Abstract Article PDF–1.6M

Select item 511159120.

11β‐Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation

Rowan S Hardy, Craig L Doig, Zahrah Hussain, Mary O'Leary, Stuart A Morgan, Mark J Pearson, Amy Naylor, Simon W Jones, Andrew Filer, Paul M Stewart, Christopher D Buckley, Gareth G Lavery, Mark S Cooper, Karim Raza

J Pathol. 2016 Dec; 240(4): 472–483. Published online 2016 Oct 18. doi: 10.1002/path.4806