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Items: 1 to 20 of 56

1.
Suppression of neuronal CDK9/p53/VDAC signaling provides bioenergetic support and improves post-stroke neuropsychiatric outcomes
Jing Xia, Tingting Zhang, Ying Sun, Zhu Huang, Dingfang Shi, Dongshen Qin, Xuejun Yang, Hao Liu, Guiying Yao, Libin Wei, Xiaoai Chang, Jun Gao, Yongjian Guo, Xiao-Yu Hou
Cell Mol Life Sci. 2024 Dec; 81(1): 384. Published online 2024 Sep 5. doi: 10.1007/s00018-024-05428-4
PMCID:
PMC11377386
AbstractArticlePDF–10M
2.
Novel complexes of cyclin-dependent kinases and a cyclin-like protein from Arabidopsis thaliana with a function unrelated to cell division
R. M. Barrôco, L. De Veylder, Z. Magyar, G. Engler, D. Inzé, V. Mironov
Cell Mol Life Sci. 2003 Feb; 60(2): 401–412. doi: 10.1007/s000180300033
PMCID:
PMC11138617
AbstractArticlePDF–912K
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
TRIB3 promotes pulmonary fibrosis through inhibiting SLUG degradation by physically interacting with MDM2
Xiaoxi Lv, Shanshan Liu, Chang Liu, Yunxuan Li, Tingting Zhang, Jie Qi, Ke Li, Fang Hua, Bing Cui, Xiaowei Zhang, Yuxin Liu, Jiaojiao Yu, Jinmei Yu, Li Li, Xia Li, Zhigang Yao, Bo Huang
Acta Pharm Sin B. 2023 Apr; 13(4): 1631–1647. Published online 2023 Jan 11. doi: 10.1016/j.apsb.2023.01.008
PMCID:
PMC10150180
AbstractArticlePDF–6.7M
5.
CDK9 binds and activates SGK3 to promote cardiac repair after injury via the GSK-3β/β-catenin pathway
Jiateng Sun, Tongtong Yang, Tianwen Wei, Liuhua Zhou, Tiankai Shan, Jiawen Chen, Lingfeng Gu, Bingrui Chen, Liu Liu, Qiqi Jiang, Chong Du, Yao Ma, Hao Wang, Feng Chen, Xuejiang Guo, Yong Ji, Liansheng Wang
Front Cardiovasc Med. 2022; 9: 970745. Published online 2022 Aug 23. doi: 10.3389/fcvm.2022.970745
PMCID:
PMC9445272
AbstractArticlePDF–1.8M
6.
The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery
Kiren Baines, Kazuaki Yoshioka, Yoh Takuwa, Jon D. Lane
Autophagy Rep. 2022; 1(1): 88–118. Published online 2022 Apr 7. doi: 10.1080/27694127.2022.2042054
PMCID:
PMC9015699
AbstractArticlePDF–3.3M
7.
CDK9 activity is critical for maintaining MDM4 overexpression in tumor cells
Monika Štětková, Kateřina Growková, Petr Fojtík, Barbora Valčíková, Veronika Palušová, Amandine Verlande, Radek Jorda, Vladimír Kryštof, Václav Hejret, Panagiotis Alexiou, Vladimír Rotrekl, Stjepan Uldrijan
Cell Death Dis. 2020 Sep; 11(9): 754. Published online 2020 Sep 15. doi: 10.1038/s41419-020-02971-3
PMCID:
PMC7494941
AbstractArticlePDF–2.2M
8.
The Role of CDKs and CDKIs in Murine Development
Grace Jean Campbell, Emma Langdale Hands, Mathew Van de Pette
Int J Mol Sci. 2020 Aug; 21(15): 5343. Published online 2020 Jul 28. doi: 10.3390/ijms21155343
PMCID:
PMC7432401
AbstractArticlePDF–613K
9.
Sirtuin 2–mediated deacetylation of cyclin-dependent kinase 9 promotes STAT1 signaling in type I interferon responses
Ewa M. Kosciuczuk, Swarna Mehrotra, Diana Saleiro, Barbara Kroczynska, Beata Majchrzak-Kita, Pawel Lisowski, Caroline Driehaus, Anna Rogalska, Acara Turner, Thomas Lienhoop, David Gius, Eleanor N. Fish, Athanassios Vassilopoulos, Leonidas C. Platanias
J Biol Chem. 2019 Jan 18; 294(3): 827–837. Published online 2018 Nov 28. doi: 10.1074/jbc.RA118.005956
PMCID:
PMC6341380
AbstractArticlePDF–1.9M
10.
ATG5 is required for B cell polarization and presentation of particulate antigens
Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros
Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327
PMCID:
PMC6333460
AbstractArticlePDF–2.7M
11.
The CDK9–cyclin T1 complex mediates saturated fatty acid–induced vascular calcification by inducing expression of the transcription factor CHOP
Yuji Shiozaki, Kayo Okamura, Shohei Kohno, Audrey L. Keenan, Kristina Williams, Xiaoyun Zhao, Wallace S. Chick, Shinobu Miyazaki-Anzai, Makoto Miyazaki
J Biol Chem. 2018 Nov 2; 293(44): 17008–17020. Published online 2018 Sep 12. doi: 10.1074/jbc.RA118.004706
PMCID:
PMC6222109
AbstractArticlePDF–1.6M
12.
Glucocorticoid-induced phosphorylation by CDK9 modulates the coactivator functions of transcriptional cofactor GRIP1 in macrophages
David A. Rollins, Joubert B. Kharlyngdoh, Maddalena Coppo, Bowranigan Tharmalingam, Sanda Mimouna, Ziyi Guo, Maria A. Sacta, Miles A. Pufall, Robert P. Fisher, Xiaoyu Hu, Yurii Chinenov, Inez Rogatsky
Nat Commun. 2017; 8: 1739. Published online 2017 Nov 23. doi: 10.1038/s41467-017-01569-2
PMCID:
PMC5700924
AbstractArticlePDF–2.4M
13.
BRD4 regulates adiponectin gene induction by recruiting the P-TEFb complex to the transcribed region of the gene
Naoko Sakurai, Yuko Inamochi, Takuya Inoue, Natsuyo Hariya, Musashi Kawamura, Masami Yamada, Anup Dey, Akira Nishiyama, Takeo Kubota, Keiko Ozato, Toshinao Goda, Kazuki Mochizuki
Sci Rep. 2017; 7: 11962. Published online 2017 Sep 20. doi: 10.1038/s41598-017-12342-2
PMCID:
PMC5607256
AbstractArticlePDF–1.8M
14.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
15.
Down-regulating cyclin-dependent kinase 9 of alloreactive CD4+ T cells prolongs allograft survival
Yang Zhan, Yeming Han, Hukui Sun, Ting Liang, Chao Zhang, Jing Song, Guihua Hou
Oncotarget. 2016 May 3; 7(18): 24983–24994. Published online 2016 Apr 18. doi: 10.18632/oncotarget.8804
PMCID:
PMC5041884
AbstractArticlePDF–8.1M
16.
The LMO2 oncogene regulates DNA replication in hematopoietic cells
Marie-Claude Sincennes, Magali Humbert, Benoît Grondin, Véronique Lisi, Diogo F. T. Veiga, André Haman, Christophe Cazaux, Nazar Mashtalir, EL Bachir Affar, Alain Verreault, Trang Hoang
Proc Natl Acad Sci U S A. 2016 Feb 2; 113(5): 1393–1398. Published online 2016 Jan 13. doi: 10.1073/pnas.1515071113
PMCID:
PMC4747768
AbstractArticlePDF–1.0M
17.
TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation
Daniil Alpern, Diana Langer, Benoit Ballester, Stephanie Le Gras, Christophe Romier, Gabrielle Mengus, Irwin Davidson
eLife. 2014; 3: e03613. Published online 2014 Sep 10. doi: 10.7554/eLife.03613
PMCID:
PMC4359380
AbstractArticlePDF–5.7M
18.
CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma
Chun-Hao Huang, Amaia Lujambio, Johannes Zuber, Darjus F. Tschaharganeh, Michael G. Doran, Michael J. Evans, Thomas Kitzing, Nan Zhu, Elisa de Stanchina, Charles L. Sawyers, Scott A. Armstrong, Jason S. Lewis, Charles J. Sherr, Scott W. Lowe
Genes Dev. 2014 Aug 15; 28(16): 1800–1814. doi: 10.1101/gad.244368.114
PMCID:
PMC4197965
AbstractArticlePDF–1.8M
19.
The Positive Transcription Elongation Factor b Is an Essential Cofactor for the Activation of Transcription by Myocyte Enhancer Factor 2
Masanori Nojima, Yehong Huang, Mudit Tyagi, Hung-Ying Kao, Koh Fujinaga
J Mol Biol. Author manuscript; available in PMC 2014 Aug 1.
Published in final edited form as: J Mol Biol. 2008 Oct 3; 382(2): 275–287. Published online 2008 Jul 16. doi: 10.1016/j.jmb.2008.07.017
PMCID:
PMC4118929
AbstractArticlePDF–1.0M
20.
SR Proteins Collaborate with 7SK and Promoter-Associated Nascent RNA to Release Paused Polymerase
Xiong Ji, Yu Zhou, Shatakshi Pandit, Jie Huang, Hairi Li, Charles Y. Lin, Rui Xiao, Christopher B. Burge, Xiang-Dong Fu
Cell. Author manuscript; available in PMC 2014 Jul 18.
Published in final edited form as: Cell. 2013 May 9; 153(4): 855–868. doi: 10.1016/j.cell.2013.04.028
PMCID:
PMC4103662
AbstractArticlePDF–1.0M

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