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Select item 114030621.

Conditional deletion of CEACAM1 in hepatic stellate cells causes their activation

Harrison T. Muturi, Hilda E. Ghadieh, Suman Asalla, Sumona G. Lester, Getachew D. Belew, Sobia Zaidi, Raziyeh Abdolahipour, Abhishek P. Shrestha, Agnes O. Portuphy, Hannah L. Stankus, Raghd Abu Helal, Stefaan Verhulst, Sergio Duarte, Ali Zarrinpar, Leo A. van Grunsven, Scott L. Friedman, Robert F. Schwabe, Terry D. Hinds, Jr., Sivarajan Kumarasamy, Sonia M. Najjar

Mol Metab. 2024 Oct; 88: 102010. Published online 2024 Aug 19. doi: 10.1016/j.molmet.2024.102010

PMCID:: PMC11403062

Abstract Article PDF–3.7M

Select item 112476762.

In vivo validation of late‐onset Alzheimer's disease genetic risk factors

Michael Sasner, Christoph Preuss, Ravi S. Pandey, Asli Uyar, Dylan Garceau, Kevin P. Kotredes, Harriet Williams, Adrian L. Oblak, Peter Bor‐Chian Lin, Bridget Perkins, Disha Soni, Cindy Ingraham, Audrey Lee‐Gosselin, Bruce T. Lamb, Gareth R. Howell, Gregory W. Carter

Alzheimers Dement. 2024 Jul; 20(7): 4970–4984. Published online 2024 Apr 30. doi: 10.1002/alz.13840

PMCID:: PMC11247676

Abstract Article PDF–3.3M

Select item 111642453.

Alternative splicing of CEACAM1 by Hypoxia-Inducible Factor–1α enhances tolerance to hepatic ischemia in mice and humans

Kenneth J. Dery, Hidenobu Kojima, Shoichi Kageyama, Kentaro Kadono, Hirofumi Hirao, Brian Cheng, Yuan Zhai, Douglas G. Farmer, Fady M. Kaldas, Xiaoyi Yuan, Holger K. Eltzschiasg, Jerzy W. Kupiec-Weglinski

Sci Transl Med. Author manuscript; available in PMC 2024 Jun 10.

Published in final edited form as: Sci Transl Med. 2023 Aug 2; 15(707): eadf2059. Published online 2023 Aug 2. doi: 10.1126/scitranslmed.adf2059

PMCID:: PMC11164245

Abstract Article PDF–2.9M

Select item 111530184.

Loss of CEACAM1 in hepatocytes causes hepatic fibrosis

Sobia Zaidi, Suman Asalla, Harrison T. Muturi, Lucia Russo, Raziyeh Abdolahipour, Getachew Debas Belew, Maria Benitez Iglesias, Mary Feraudo, Lensay Leon, Enoch Kuo, Xiuli Liu, Sivarajan Kumarasamy, Hilda E. Ghadieh, Cara Gatto-Weis, Ali Zarrinpar, Sergio Duarte, Sonia M. Najjar

Eur J Clin Invest. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: Eur J Clin Invest. 2024 Jul; 54(7): e14177. Published online 2024 Feb 21. doi: 10.1111/eci.14177

PMCID:: PMC11153018

Abstract Article PDF–1.9M

Select item 103301965.

Loss of CEACAM1 in endothelial cells causes hepatic fibrosis

Harrison T. Muturi, Hilda E. Ghadieh, Raziyeh Abdolahipour, Hannah L. Stankus, Getachew Debas Belew, James K. Liu, Marziyeh Salehi Jahromi, Abraham D. Lee, Bernhard B. Singer, Isabella Angeli-Pahim, Tejasav S. Sehrawat, Harmeet Malhi, Stefaan Verhulst, Leo A. van Grunsven, Ali Zarrinpar, Sergio Duarte, Sonia M. Najjar

Metabolism. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: Metabolism. 2023 Jul; 144: 155562. Published online 2023 Apr 21. doi: 10.1016/j.metabol.2023.155562

PMCID:: PMC10330196

Abstract Article PDF–3.0M

Select item 101914416.

USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities

Chao Liu, Lingang Sun, Yijun Tan, Qi Wang, Tao Luo, Chenlu Li, Nan Yao, Yuting Xie, Xiao Yi, Yi Zhu, Tiannan Guo, Junfeng Ji

Sci Adv. 2023 May; 9(20): eade3888. Published online 2023 May 17. doi: 10.1126/sciadv.ade3888

PMCID:: PMC10191441

Abstract Article PDF–2.4M

Select item 98883877.

Neutrophil CEACAM1 determines susceptibility to NETosis by regulating the S1PR2/S1PR3 axis in liver transplantation

Hirofumi Hirao, Hidenobu Kojima, Kenneth J. Dery, Kojiro Nakamura, Kentaro Kadono, Yuan Zhai, Douglas G. Farmer, Fady M. Kaldas, Jerzy W. Kupiec-Weglinski

J Clin Invest. 2023 Feb 1; 133(3): e162940. Published online 2023 Feb 1. doi: 10.1172/JCI162940

PMCID:: PMC9888387

Abstract Article PDF–18M

Select item 96353078.

CEACAM1 specifically suppresses B cell receptor signaling-mediated activation

Naoya Tsugawa, Daiki Yamada, Taro Watabe, Michio Onizawa, Shuang Wang, Yasuhiro Nemoto, Shigeru Oshima, Takeshi Tsubata, Takahiro Adachi, Yohei Kawano, Mamoru Watanabe, Richard S. Blumberg, Ryuichi Okamoto, Takashi Nagaishi

Biochem Biophys Res Commun. Author manuscript; available in PMC 2022 Nov 4.

Published in final edited form as: Biochem Biophys Res Commun. 2021 Jan 8; 535: 99–105. Published online 2020 Dec 21. doi: 10.1016/j.bbrc.2020.11.126

Correction in:: Biochem Biophys Res Commun. 2021 Aug 6; 565: 97.

PMCID:: PMC9635307

Abstract Article PDF–1.1M

Select item 90271029.

Aortic Fibrosis in Insulin-Sensitive Mice with Endothelial Cell-Specific Deletion of Ceacam1 Gene

Raghd Abu Helal, Harrison T. Muturi, Abraham D. Lee, Wei Li, Hilda E. Ghadieh, Sonia M. Najjar

Int J Mol Sci. 2022 Apr; 23(8): 4335. Published online 2022 Apr 14. doi: 10.3390/ijms23084335

PMCID:: PMC9027102

Abstract Article PDF–3.0M

Select item 857715610.

Human CEACAM1-LF regulates lipid storage in HepG2 cells via fatty acid transporter CD36

Jennifer Chean, Charng-Jui Chen, Gabriel Gugiu, Patty Wong, Seung Cha, Harry Li, Tung Nguyen, Supriyo Bhatticharya, John E. Shively

J Biol Chem. 2021 Nov; 297(5): 101311. Published online 2021 Oct 16. doi: 10.1016/j.jbc.2021.101311

PMCID:: PMC8577156

Abstract Article PDF–6.4M

Select item 839479011.

Insulin Sensitivity Is Retained in Mice with Endothelial Loss of Carcinoembryonic Antigen Cell Adhesion Molecule 1

Harrison T. Muturi, Saja S. Khuder, Hilda E. Ghadieh, Emily L. Esakov, Hyelim Noh, Heejoon Kang, Marcia F. McInerney, Jason K. Kim, Abraham D. Lee, Sonia M. Najjar

Cells. 2021 Aug; 10(8): 2093. Published online 2021 Aug 14. doi: 10.3390/cells10082093

PMCID:: PMC8394790

Abstract Article PDF–2.9M

Select item 828697012.

Regulation of hepatic fibrosis by Carcinoembryonic Antigen-related Cell Adhesion Molecule 1

Raghd Abu Helal, Lucia Russo, Hilda E. Ghadieh, Harrison T. Muturi, Suman Asalla, Abraham D. Lee, Cara Gatto-Weis, Sonia M. Najjar

Metabolism. Author manuscript; available in PMC 2022 Aug 1.

Published in final edited form as: Metabolism. 2021 Aug; 121: 154801. Published online 2021 May 28. doi: 10.1016/j.metabol.2021.154801

PMCID:: PMC8286970

Abstract Article PDF–1.9M

Select item 828053413.

Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors

Laura M. Molina, Junjie Zhu, Qin Li, Tirthadipa Pradhan-Sundd, Yekaterina Krutsenko, Khaled Sayed, Nathaniel Jenkins, Ravi Vats, Bharat Bhushan, Sungjin Ko, Shikai Hu, Minakshi Poddar, Sucha Singh, Junyan Tao, Prithu Sundd, Aatur Singhi, Simon Watkins, Xiaochao Ma, Panayiotis V. Benos, Andrew Feranchak, George Michalopoulos, Kari Nejak-Bowen, Alan Watson, Aaron Bell, Satdarshan P. Monga

Cell Rep. Author manuscript; available in PMC 2021 Jul 15.

Published in final edited form as: Cell Rep. 2021 Jul 6; 36(1): 109310. doi: 10.1016/j.celrep.2021.109310

PMCID:: PMC8280534

Abstract Article PDF–2.1M

Select item 753495414.

Neutrophil Extracellular Trap–Associated CEACAM1 as a Putative Therapeutic Target to Prevent Metastatic Progression of Colon Carcinoma

Roni F. Rayes, Phil Vourtzoumis, Marianne Bou Rjeily, Rashmi Seth, France Bourdeau, Betty Giannias, Julie Berube, Yu-Hwa Huang, Simon Rousseau, Sophie Camilleri-Broet, Richard S. Blumberg, Nicole Beauchemin, Sara Najmeh, Jonathan Cools-Lartigue, Jonathan D. Spicer, Lorenzo E. Ferri

J Immunol. Author manuscript; available in PMC 2020 Oct 5.

Published in final edited form as: J Immunol. 2020 Apr 15; 204(8): 2285–2294. Published online 2020 Mar 13. doi: 10.4049/jimmunol.1900240

PMCID:: PMC7534954

Abstract Article PDF–1.2M

Select item 752415515.

CEACAM1 regulates CD8⁺ T cell immunity and protects from severe pathology during Citrobacter rodentium induced colitis

Julia Zöller, Jana-Fabienne Ebel, Vishal Khairnar, Verena Schmitt, Robert Klopfleisch, Jana Meiners, Virginia Seiffart, Wiebke Hansen, Jan Buer, Bernhard B. Singer, Karl S. Lang, Astrid M. Westendorf

Gut Microbes. 2020; 11(6): 1790–1805. Published online 2020 Jun 10. doi: 10.1080/19490976.2020.1775464

PMCID:: PMC7524155

Abstract Article PDF–16M

Select item 732779816.

TIM3 comes of age as an inhibitory receptor

Yochai Wolf, Ana C. Anderson, Vijay K. Kuchroo

Nat Rev Immunol. Author manuscript; available in PMC 2020 Jul 1.

Published in final edited form as: Nat Rev Immunol. 2020 Mar; 20(3): 173–185. Published online 2019 Nov 1. doi: 10.1038/s41577-019-0224-6

PMCID:: PMC7327798

Abstract Article PDF–1.1M

Select item 728300217.

Loss of Ceacam1 promotes prostate cancer progression in Pten haploinsufficient male mice

Jehnan Liu, Harrison T. Muturi, Saja S. Khuder, Raghd Abu Helal, Hilda E. Ghadieh, Sadeesh K. Ramakrishnan, Meenakshi K. Kaw, Sumona Ghosh Lester, Ahmed Al-Khudhair, Philip B. Conran, Khew-Voon Chin, Cara Gatto-Weis, Sonia M. Najjar

Metabolism. Author manuscript; available in PMC 2021 Jun 1.

Published in final edited form as: Metabolism. 2020 Jun; 107: 154215. Published online 2020 Mar 21. doi: 10.1016/j.metabol.2020.154215

PMCID:: PMC7283002

Abstract Article PDF–2.3M

Select item 719091718.

Hepatic CEACAM1 expression indicates donor liver quality and prevents early transplantation injury

Kojiro Nakamura, Shoichi Kageyama, Fady M. Kaldas, Hirofumi Hirao, Takahiro Ito, Kentaro Kadono, Kenneth J. Dery, Hidenobu Kojima, David W. Gjertson, Rebecca A. Sosa, Maciej Kujawski, Ronald W. Busuttil, Elaine F. Reed, Jerzy W. Kupiec-Weglinski

J Clin Invest. 2020 May 1; 130(5): 2689–2704. Published online 2020 Apr 20. doi: 10.1172/JCI133142

PMCID:: PMC7190917

Abstract Article PDF–17M

Select item 713161919.

Expression of the Bgp gene and characterization of mouse colon biliary glycoprotein isoforms

Kimberly McCuaig, Madelaine Rosenberg, Patrick Nédellec, Claire Turbide, Nicole Beauchemin

Gene. 1993 May 30; 127(2): 173–183. Published online 2003 Jan 15. doi: 10.1016/0378-1119(93)90716-G

PMCID:: PMC7131619

Abstract Article PDF–1.4M

Select item 712782020.

Amino acid substitutions and an insertion in the spike glycoprotein extend the host range of the murine coronavirus MHV-A59

Larissa B Thackray, Kathryn V Holmes

Virology. 2004 Jul 1; 324(2): 510–524. Published online 2004 May 18. doi: 10.1016/j.virol.2004.04.005

PMCID:: PMC7127820

Abstract Article PDF–1.7M

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