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Select item 111094831.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 109714362.

Lupus susceptibility gene Pbx1 controls the development, stability, and function of regulatory T cells via Rtkn2 expression

Seung-Chul Choi, Yuk Pheel Park, Tracoyia Roach, Damian Jimenez, Amanda Fisher, Mojgan Zadeh, Longhuan Ma, Eric S. Sobel, Yong Ge, Mansour Mohamadzadeh, Laurence Morel

Sci Adv. 2024 Mar 29; 10(13): eadi4310. Published online 2024 Mar 27. doi: 10.1126/sciadv.adi4310

PMCID:: PMC10971436

Abstract Article PDF–6.5M

Select item 109332673.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 107991044.

Small nucleolar RNA Snora73 promotes psoriasis progression by sponging miR-3074-5p and regulating PBX1 expression

Lihua Zhang, Hui Guo, Xiaoguang Zhang, Ling Wang, Feng Wei, Yike Zhao, Bo Wang, Yibo Meng, Yanling Li

Funct Integr Genomics. 2024; 24(1): 15. Published online 2024 Jan 19. doi: 10.1007/s10142-024-01300-7

Correction in:: Funct Integr Genomics. 2024; 24(1): 21.

PMCID:: PMC10799104

Abstract Article PDF–1.9M

Select item 107633345.

Extracellular vesicle-derived TP53BP1, CD34, and PBX1 from human peripheral blood serve as potential biomarkers for the assessment and prediction of vascular aging

Yichao Wen, Haiyang Chen, Yu Wang, Yiqing Sun, Fangfang Dou, Xiling Du, Te Liu, Chuan Chen

Hereditas. 2024; 161: 3. Published online 2024 Jan 3. doi: 10.1186/s41065-023-00306-8

PMCID:: PMC10763334

Abstract Article PDF–7.1M

Select item 104998956.

Molecular characterization of TCF3::PBX1 chromosomal breakpoints in acute lymphoblastic leukemia and their use for measurable residual disease assessment

Thomas Burmeister, Daniela Gröger, Nicola Gökbuget, Bernd Spriewald, Michael Starck, Ahmet Elmaagacli, Dieter Hoelzer, Ulrich Keller, Stefan Schwartz

Sci Rep. 2023; 13: 15167. Published online 2023 Sep 13. doi: 10.1038/s41598-023-42294-9

PMCID:: PMC10499895

Abstract Article PDF–1.3M

Select item 102660817.

TRIM26 promotes non-small cell lung cancer survival by inducing PBX1 degradation

Yuening Sun, Peng Lin, Xiumin Zhou, Ying Ren, Yuanming He, Jingpei Liang, Zhigang Zhu, Xiaofeng Xu, Xinliang Mao

Int J Biol Sci. 2023; 19(9): 2803–2816. Published online 2023 May 29. doi: 10.7150/ijbs.81726

PMCID:: PMC10266081

Abstract Article PDF–6.7M

Select item 96722668.

PBX1 attenuates H₂O₂-induced oxidant stress in human trabecular meshwork cells via promoting NANOG-mediated PI3K/AKT signaling pathway

Liang Wang, Ying Tian, Yan Cao, Qiang Ma, Shuai Zhao

Cell Stress Chaperones. 2022 Nov; 27(6): 673–684. Published online 2022 Oct 18. doi: 10.1007/s12192-022-01304-x

PMCID:: PMC9672266

Abstract Article PDF–2.4M

Select item 96573079.

Targeting SPHK1/PBX1 Axis Induced Cell Cycle Arrest in Non-Small Cell Lung Cancer

Zhoujun Lin, Yin Li, Xiao Han, Zhenkun Fu, Zhenhuan Tian, Chenggang Li

Int J Mol Sci. 2022 Nov; 23(21): 12741. Published online 2022 Oct 22. doi: 10.3390/ijms232112741

PMCID:: PMC9657307

Abstract Article PDF–12M

Select item 945849210.

Genetic features of B‐cell lymphoblastic lymphoma with TCF3‐PBX1

Ryota Shirai, Tomoo Osumi, Aiko Sato‐Otsubo, Kazuhiko Nakabayashi, Takeshi Mori, Masanori Yoshida, Kaoru Yoshida, Mika Kohri, Takashi Ishihara, Shiho Yasue, Toshihiko Imamura, Mikiya Endo, Satoshi Miyamoto, Kentaro Ohki, Masashi Sanada, Nobutaka Kiyokawa, Seishi Ogawa, Takako Yoshioka, Kenichiro Hata, Masatoshi Takagi, Motohiro Kato

Cancer Rep (Hoboken) 2022 Sep; 5(9): e1559. Published online 2021 Sep 23. doi: 10.1002/cnr2.1559

PMCID:: PMC9458492

Abstract Article PDF–1.9M

Select item 934857611.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 911973612.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 892305713.

Transcription Factor Protein Interactomes Reveal Genetic Determinants in Heart Disease

Barbara Gonzalez-Teran, Maureen Pittman, Franco Felix, Reuben Thomas, Desmond Richmond-Buccola, Ruth Hüttenhain, Krishna Choudhary, Elisabetta Moroni, Mauro W. Costa, Yu Huang, Arun Padmanabhan, Michael Alexanian, Clara Youngna Lee, Bonnie E. J. Maven, Kaitlen Samse-Knapp, Sarah U. Morton, Michael McGregor, Casey A. Gifford, J. G. Seidman, Christine E. Seidman, Bruce D. Gelb, Giorgio Colombo, Bruce R. Conklin, Brian L. Black, Benoit G. Bruneau, Nevan J. Krogan, Katherine S. Pollard, Deepak Srivastava

Cell. Author manuscript; available in PMC 2023 Mar 3.

Published in final edited form as: Cell. 2022 Mar 3; 185(5): 794–814.e30. Published online 2022 Feb 18. doi: 10.1016/j.cell.2022.01.021

PMCID:: PMC8923057

Abstract Article PDF–2.5M

Select item 882889514.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 848764715.

Genome-Wide Association Study of Susceptibility Loci for TCF3-PBX1 Acute Lymphoblastic Leukemia in Children

Shawn H. R Lee, Maoxiang Qian, Wentao Yang, Jonathan D Diedrich, Elizabeth Raetz, Wenjian Yang, Qian Dong, Meenakshi Devidas, Deqing Pei, Allen Yeoh, Cheng Cheng, Ching-Hon Pui, William E Evans, Charles G Mullighan, Stephen P Hunger, Daniel Savic, Mary V Relling, Mignon L Loh, Jun J Yang

J Natl Cancer Inst. 2021 Jul; 113(7): 933–937. Published online 2020 Sep 14. doi: 10.1093/jnci/djaa133

PMCID:: PMC8487647

Abstract Article PDF–1016K

Select item 819863116.

A Computer-Based Methodology to Design Non-Standard Peptides Potentially Able to Prevent HOX-PBX1-Associated Cancer Diseases

Maria Rita Gulotta, Giada De Simone, Justin John, Ugo Perricone, Andrea Brancale

Int J Mol Sci. 2021 Jun; 22(11): 5670. Published online 2021 May 26. doi: 10.3390/ijms22115670

PMCID:: PMC8198631

Abstract Article PDF–7.5M

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 800904818.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 786137919.

Establishment of the TALE-code reveals aberrantly activated homeobox gene PBX1 in Hodgkin lymphoma

Stefan Nagel, Claudia Pommerenke, Corinna Meyer, Roderick A. F. MacLeod, Hans G. Drexler

PLoS One. 2021; 16(2): e0246603. Published online 2021 Feb 4. doi: 10.1371/journal.pone.0246603

PMCID:: PMC7861379

Abstract Article PDF–3.1M

Select item 754509720.

Mapping the native interaction surfaces of PREP1 with PBX1 by cross-linking mass-spectrometry and mutagenesis

Chiara Bruckmann, Simone Tamburri, Valentina De Lorenzi, Nunzianna Doti, Alessandra Monti, Lisa Mathiasen, Angela Cattaneo, Menotti Ruvo, Angela Bachi, Francesco Blasi

Sci Rep. 2020; 10: 16809. Published online 2020 Oct 8. doi: 10.1038/s41598-020-74032-w

PMCID:: PMC7545097

Abstract Article PDF–4.5M

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