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Items: 1 to 20 of 97

1.
Protein translation rate determines neocortical neuron fate
Ekaterina Borisova, Andrew G. Newman, Marta Couce Iglesias, Rike Dannenberg, Theres Schaub, Bo Qin, Alexandra Rusanova, Marisa Brockmann, Janina Koch, Marieatou Daniels, Paul Turko, Olaf Jahn, David R. Kaplan, Marta Rosário, Takao Iwawaki, Christian M. T. Spahn, Christian Rosenmund, David Meierhofer, Matthew L. Kraushar, Victor Tarabykin, Mateusz C. Ambrozkiewicz
Nat Commun. 2024; 15: 4879. Published online 2024 Jun 7. doi: 10.1038/s41467-024-49198-w
PMCID:
PMC11161512
AbstractArticlePDF–17M
2.
Impact of eIF2α phosphorylation on the translational landscape of mouse embryonic stem cells
Mehdi Amiri, Stephen J. Kiniry, Anthony P. Possemato, Niaz Mahmood, Tayebeh Basiri, Catherine R. Dufour, Negar Tabatabaei, Qiyun Deng, Michael A. Bellucci, Keerthana Harwalkar, Matthew P. Stokes, Vincent Giguère, Randal J. Kaufman, Yojiro Yamanaka, Pavel V. Baranov, Soroush Tahmasebi, Nahum Sonenberg
Cell Rep. Author manuscript; available in PMC 2024 Mar 25.
Published in final edited form as: Cell Rep. 2024 Jan 23; 43(1): 113615. Published online 2023 Dec 29. doi: 10.1016/j.celrep.2023.113615
PMCID:
PMC10962698
AbstractArticlePDF–2.5M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment
Jiawen Xiang, Anthony J. Pompetti, Adam P. Faranda, Yan Wang, Samuel G. Novo, David Wan-Cheng Li, Melinda K. Duncan
Cells. 2023 Nov; 12(22): 2636. Published online 2023 Nov 16. doi: 10.3390/cells12222636
PMCID:
PMC10670291
AbstractArticlePDF–9.2M
5.
Impairment of serine transport across the blood–brain barrier by deletion of Slc38a5 causes developmental delay and motor dysfunction
Inna Radzishevsky, Maali Odeh, Oded Bodner, Salman Zubedat, Lihi Shaulov, Maxim Litvak, Kayoko Esaki, Takeo Yoshikawa, Bella Agranovich, Wen-Hong Li, Alex Radzishevsky, Eyal Gottlieb, Avi Avital, Herman Wolosker
Proc Natl Acad Sci U S A. 2023 Oct 17; 120(42): e2302780120. Published online 2023 Oct 9. doi: 10.1073/pnas.2302780120
PMCID:
PMC10589673
AbstractArticlePDF–6.8M
6.
Activation of BZW1 by CEBPB in macrophages promotes eIF2α phosphorylation-mediated metabolic reprogramming and endoplasmic reticulum stress in MRL/lpr lupus-prone mice
Huimeng Qi, Zhaoguo Zheng, Qiang Liu
Cell Mol Biol Lett. 2023; 28: 79. Published online 2023 Oct 12. doi: 10.1186/s11658-023-00494-1
PMCID:
PMC10571419
AbstractArticlePDF–6.7M
7.
Oxidized phospholipids facilitate calcific aortic valve disease by elevating ATF4 through the PERK/eIF2α axis
Xiaohua Zhu, Linjie Yang, Xu Han, Chen Huang, Gongcheng Huang, Tingju Wei, Liliang Shu, Jing Xu
Aging (Albany NY) 2023 Jul 31; 15(14): 6834–6847. Published online 2023 Jul 17. doi: 10.18632/aging.204875
PMCID:
PMC10415544
AbstractArticlePDF–1.1M
8.
DELE1 is protective for mitochondrial cardiomyopathy
Helen Huynh, Siting Zhu, Sharon Lee, Yutong Bao, Jing Pang, Anh Nguyen, Yusu Gu, Chao Chen, Kunfu Ouyang, Sylvia M. Evans, Xi Fang
J Mol Cell Cardiol. Author manuscript; available in PMC 2023 Jul 30.
Published in final edited form as: J Mol Cell Cardiol. 2023 Feb; 175: 44–48. Published online 2022 Dec 17. doi: 10.1016/j.yjmcc.2022.12.003
PMCID:
PMC10387237
AbstractArticlePDF–661K
9.
HIF1 inhibitor acriflavine rescues early-onset preeclampsia phenotype in mice lacking placental prolyl hydroxylase domain protein 2
Julien Sallais, Chanho Park, Sruthi Alahari, Tyler Porter, Ruizhe Liu, Merve Kurt, Abby Farrell, Martin Post, Isabella Caniggia
JCI Insight. 2022 Dec 8; 7(23): e158908. Published online 2022 Dec 8. doi: 10.1172/jci.insight.158908
PMCID:
PMC9746916
AbstractArticlePDF–7.1M
10.
Mitochondrial stress induces an HRI-eIF2α pathway protective for cardiomyopathy
Siting Zhu, Anh Nguyen, Jing Pang, Jun Zhao, Ze’e Chen, Zhengyu Liang, Yusu Gu, Helen Huynh, Yutong Bao, Sharon Lee, Yuval Kluger, Kunfu Ouyang, Sylvia M Evans, Xi Fang
Circulation. Author manuscript; available in PMC 2023 Sep 27.
Published in final edited form as: Circulation. 2022 Sep 27; 146(13): 1028–1031. Published online 2022 Sep 26. doi: 10.1161/CIRCULATIONAHA.122.059594
PMCID:
PMC9523491
ArticlePDF–1016K
11.
Paternal obesity induces placental hypoxia and sex-specific impairments in placental vascularization and offspring metabolism
Patrycja A Jazwiec, Violet S Patterson, Tatiane A Ribeiro, Erica Yeo, Katherine M Kennedy, Paulo C F Mathias, Jim J Petrik, Deborah M Sloboda
Biol Reprod. 2022 Aug; 107(2): 574–589. Published online 2022 Apr 4. doi: 10.1093/biolre/ioac066
PMCID:
PMC9382389
AbstractArticlePDF–1.7M
12.
Activation of the transcription factor NRF2 mediates the anti-inflammatory and tissue protective properties of a subset of over-the-counter and prescription NSAIDs
Anna Eisenstein, Brandon K. Hilliard, Scott D. Pope, Cuiling Zhang, Pranali Taskar, Daniel A. Waizman, Kavita Israni-Winger, Hui Tian, Harding H. Luan, Andrew Wang
Immunity. Author manuscript; available in PMC 2023 Jun 14.
Published in final edited form as: Immunity. 2022 Jun 14; 55(6): 1082–1095.e5. Published online 2022 May 18. doi: 10.1016/j.immuni.2022.04.015
PMCID:
PMC9205175
AbstractArticlePDF–2.3M
13.
eIF2A‐knockout mice reveal decreased life span and metabolic syndrome
Richard Anderson, Anchal Agarwal, Arnab Ghosh, Bo‐Jhih Guan, Jackson Casteel, Nina Dvorina, William M. Baldwin, 3rd, Barsanjit Mazumder, Taras Y. Nazarko, William C. Merrick, David A. Buchner, Maria Hatzoglou, Roman V. Kondratov, Anton A. Komar
FASEB J. 2021 Nov; 35(11): e21990. Published online 2021 Oct 19. doi: 10.1096/fj.202101105R
Correction in:
FASEB J. 2023 Feb; 37(2): e22759.
PMCID:
PMC8848898
AbstractArticlePDF–3.0M
14.
The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins
Mickaële Hémono, Alexandre Haller, Johana Chicher, Anne-Marie Duchêne, Richard Patryk Ngondo
BMC Biol. 2022; 20: 13. Published online 2022 Jan 10. doi: 10.1186/s12915-021-01213-y
PMCID:
PMC8744257
AbstractArticlePDF–6.0M
15.
H19X‐encoded miR‐322(424)/miR‐503 regulates muscle mass by targeting translation initiation factors
Rui Liang, Xiaopeng Shen, Fan Wang, Xin Wang, Alex DesJarlais, Anam Syed, Raymond Saba, Zhi Tan, Fang Yu, Xuan Ji, Shreesti Shrestha, Yinghong Ren, Jin Yang, Yoonjung Park, Robert J. Schwartz, Benjamin Soibam, Bradley K. McConnell, M. David Stewart, Ashok Kumar, Yu Liu
J Cachexia Sarcopenia Muscle. 2021 Dec; 12(6): 2174–2186. Published online 2021 Oct 26. doi: 10.1002/jcsm.12827
PMCID:
PMC8718088
AbstractArticlePDF–9.5M
16.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
17.
Maternal Immune Activation in Mice Disrupts Proteostasis in the Fetal Brain
Brian T. Kalish, Eunha Kim, Benjamin Finander, Erin E. Duffy, Hyunju Kim, Casey K. Gilman, Yeong Shin Yim, Lilin Tong, Randal J. Kaufman, Eric C. Griffith, Gloria B. Choi, Michael E. Greenberg, Jun R. Huh
Nat Neurosci. Author manuscript; available in PMC 2021 Jun 23.
Published in final edited form as: Nat Neurosci. 2021 Feb; 24(2): 204–213. Published online 2020 Dec 23. doi: 10.1038/s41593-020-00762-9
PMCID:
PMC7854524
AbstractArticlePDF–5.7M
18.
Expression of the Neuronal tRNA n-Tr20 Regulates Synaptic Transmission and Seizure Susceptibility
Mridu Kapur, Archan Ganguly, Gabor Nagy, Scott I. Adamson, Jeffrey H. Chuang, Wayne N. Frankel, Susan L. Ackerman
Neuron. Author manuscript; available in PMC 2021 Oct 14.
Published in final edited form as: Neuron. 2020 Oct 14; 108(1): 193–208.e9. Published online 2020 Aug 26. doi: 10.1016/j.neuron.2020.07.023
PMCID:
PMC7572898
AbstractArticlePDF–2.1M
19.
Restoring BMP4 expression in vascular endothelial progenitors ameliorates maternal diabetes-induced apoptosis and neural tube defects
Songying Cao, E. Albert Reece, Wei-Bin Shen, Peixin Yang
Cell Death Dis. 2020 Oct; 11(10): 859. Published online 2020 Oct 15. doi: 10.1038/s41419-020-03078-5
PMCID:
PMC7562732
AbstractArticlePDF–1.9M
20.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M

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