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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108865952.

The BK Channel Limits the Pro-Inflammatory Activity of Macrophages

Yihe Chen, Nikita Markov, Lea Gigon, Aref Hosseini, Shida Yousefi, Darko Stojkov, Hans-Uwe Simon

Cells. 2024 Feb; 13(4): 322. Published online 2024 Feb 9. doi: 10.3390/cells13040322

PMCID:: PMC10886595

Abstract Article PDF–2.6M

Select item 104015443.

Slo1 deficiency impaired skeletal muscle regeneration and slow‐twitch fibre formation

Chao Xia, Yonghui Wang, Tianyuan Jiang, Yan Hu, Yang Chen, Xinrun Ma, Xuemei Zhang, Yanhong Gao

J Cachexia Sarcopenia Muscle. 2023 Aug; 14(4): 1737–1752. Published online 2023 May 22. doi: 10.1002/jcsm.13253

PMCID:: PMC10401544

Abstract Article PDF–7.7M

Select item 103802664.

Hyperacusis in the Adult Fmr1-KO Mouse Model of Fragile X Syndrome: The Therapeutic Relevance of Cochlear Alterations and BKCa Channels

Celeste Ferraguto, Yohan Bouleau, Thibault Peineau, Didier Dulon, Susanna Pietropaolo

Int J Mol Sci. 2023 Jul; 24(14): 11863. Published online 2023 Jul 24. doi: 10.3390/ijms241411863

PMCID:: PMC10380266

Abstract Article PDF–3.2M

Select item 98033605.

Tbx2 is a master regulator of inner versus outer hair cell differentiation

Jaime García-Añoveros, John C. Clancy, Chuan Zhi Foo, Ignacio García-Gómez, Yingjie Zhou, Kazuaki Homma, Mary Ann Cheatham, Anne Duggan

Nature. Author manuscript; available in PMC 2022 Dec 30.

Published in final edited form as: Nature. 2022 May; 605(7909): 298–303. Published online 2022 May 4. doi: 10.1038/s41586-022-04668-3

PMCID:: PMC9803360

Abstract Article PDF–4.3M

Select item 92758236.

BK channel properties correlate with neurobehavioral severity in three KCNMA1-linked channelopathy mouse models

Su Mi Park, Cooper E Roache, Philip H Iffland, II, Hans J Moldenhauer, Katia K Matychak, Amber E Plante, Abby G Lieberman, Peter B Crino, Andrea Meredith

eLife. 2022; 11: e77953. Published online 2022 Jul 12. doi: 10.7554/eLife.77953

PMCID:: PMC9275823

Abstract Article PDF–3.9M

Select item 89442727.

Neuronal mechanism of a BK channelopathy in absence epilepsy and dyskinesia

Ping Dong, Yang Zhang, Arsen S. Hunanyan, Mohamad A. Mikati, Jianmin Cui, Huanghe Yang

Proc Natl Acad Sci U S A. 2022 Mar 22; 119(12): e2200140119. Published online 2022 Mar 14. doi: 10.1073/pnas.2200140119

PMCID:: PMC8944272

Abstract Article PDF–3.9M

Select item 87937848.

Molecular Mechanisms of Epileptic Encephalopathy Caused by KCNMA1 Loss-of-Function Mutations

Yu Yao, Dongxiao Qu, Xiaoping Jing, Yuxiang Jia, Qi Zhong, Limin Zhuo, Xingxing Chen, Guoyi Li, Lele Tang, Yudan Zhu, Xuemei Zhang, Yonghua Ji, Zhiping Li, Jie Tao

Front Pharmacol. 2021; 12: 775328. Published online 2022 Jan 13. doi: 10.3389/fphar.2021.775328

PMCID:: PMC8793784

Abstract Article PDF–4.3M

Select item 84919049.

Electromagnetic energy (670 nm) stimulates vasodilation through activation of the large conductance potassium channel (BK_Ca)

Debebe Gebremendhin, Brian Lindemer, Dorothee Weihrauch, David R. Harder, Nicole L. Lohr

PLoS One. 2021; 16(10): e0257896. Published online 2021 Oct 5. doi: 10.1371/journal.pone.0257896

PMCID:: PMC8491904

Abstract Article PDF–1.4M

Select item 842414410.

BK Channel Deficiency in Osteoblasts Reduces Bone Formation via the Wnt/^β-Catenin Pathway

Lan Jiang, Qianhong Yang, Jianjun Gao, Jiahong Yang, Jiaqi He, Hong Xin, Xuemei Zhang

Mol Cells. 2021 Aug 31; 44(8): 557–568. Published online 2021 Aug 13. doi: 10.14348/molcells.2021.0004

PMCID:: PMC8424144

Abstract Article PDF–41M

Select item 782636711.

Goblet cell LRRC26 regulates BK channel activation and protects against colitis in mice

Vivian Gonzalez-Perez, Pedro L. Martinez-Espinosa, Monica Sala-Rabanal, Nikhil Bharadwaj, Xiao-Ming Xia, Albert C. Chen, David Alvarado, Jenny K. Gustafsson, Hongzhen Hu, Matthew A. Ciorba, Christopher J. Lingle

Proc Natl Acad Sci U S A. 2021 Jan 19; 118(3): e2019149118. Published online 2021 Jan 11. doi: 10.1073/pnas.2019149118

PMCID:: PMC7826367

Abstract Article PDF–2.2M

Select item 775625212.

Upregulated LRRC55 promotes BK channel activation and aggravates cell injury in podocytes

Shuai Hu, Runhong Han, Long Chen, Weisong Qin, Xiaodong Xu, Jingsong Shi, Xiaodong Zhu, Mingchao Zhang, Caihong Zeng, Zheng Tang, Hao Bao, Zhihong Liu

J Exp Med. 2021 Feb 1; 218(2): e20192373. Published online 2020 Dec 21. doi: 10.1084/jem.20192373

PMCID:: PMC7756252

Abstract Article PDF–6.2M

Select item 720542613.

Intercalated cell BKα subunit is required for flow-induced K⁺ secretion

Rolando Carrisoza-Gaytan, Evan C. Ray, Daniel Flores, Allison L. Marciszyn, Peng Wu, Leah Liu, Arohan R. Subramanya, WenHui Wang, Shaohu Sheng, Lubika J. Nkashama, Jingxin Chen, Edwin K. Jackson, Stephanie M. Mutchler, Szilvia Heja, Donald E. Kohan, Lisa M. Satlin, Thomas R. Kleyman

JCI Insight. 2020 Apr 23; 5(8): e130553. Published online 2020 Apr 23. doi: 10.1172/jci.insight.130553

PMCID:: PMC7205426

Abstract Article PDF–8.2M

Select item 697842314.

A lysosomal K⁺ channel regulates large particle phagocytosis by facilitating lysosome Ca²⁺ release

Xue Sun, Mengnan Xu, Qi Cao, Peng Huang, Xiaojuan Zhu, Xian-Ping Dong

Sci Rep. 2020; 10: 1038. Published online 2020 Jan 23. doi: 10.1038/s41598-020-57874-2

PMCID:: PMC6978423

Abstract Article PDF–3.7M

Select item 677268815.

A Novel Nervous System β Subunit that Downregulates Human Large Conductance Calcium-Dependent Potassium Channels

Thomas M. Weiger, Mats H. Holmqvist, Irwin B. Levitan, Frederick T. Clark, Scott Sprague, Wann-Jeng Huang, Pei Ge, Chichung Wang, Deborah Lawson, Mark E. Jurman, M. Alexandra Glucksmann, Inmaculada Silos-Santiago, Peter S. DiStefano, Rory Curtis

J Neurosci. 2000 May 15; 20(10): 3563–3570. doi: 10.1523/JNEUROSCI.20-10-03563.2000