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Select item 102374221.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 99868172.

METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m⁶A homeostasis

Zhan‐Cheng Zeng, Qi Pan, Yu‐Meng Sun, Heng‐Jing Huang, Xiao‐Tong Chen, Tian‐Qi Chen, Bo He, Hua Ye, Shun‐Xin Zhu, Ke‐Jia Pu, Ke Fang, Wei Huang, Yue‐Qin Chen, Wen‐Tao Wang

EMBO Rep. 2023 Mar; 24(3): e55762. Published online 2023 Jan 4. doi: 10.15252/embr.202255762

PMCID:: PMC9986817

Abstract Article PDF–3.5M

Select item 95262563.

A standardized nomenclature for mammalian histone genes

Ruth L. Seal, Paul Denny, Elspeth A. Bruford, Anna K. Gribkova, David Landsman, William F. Marzluff, Monica McAndrews, Anna R. Panchenko, Alexey K. Shaytan, Paul B. Talbert

Epigenetics Chromatin. 2022; 15: 34. Published online 2022 Oct 1. doi: 10.1186/s13072-022-00467-2

PMCID:: PMC9526256

Abstract Article PDF–1.1M

Select item 93383134.

HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4

PMCID:: PMC9338313

Abstract Article PDF–2.8M

Select item 85529075.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 83731426.

The conserved Tpk1 regulates non-homologous end joining double-strand break repair by phosphorylation of Nej1, a homolog of the human XLF

Matthew Jessulat, Shahreen Amin, Mohsen Hooshyar, Ramy Malty, Mohamed Taha Moutaoufik, Mara Zilocchi, Zoe Istace, Sadhna Phanse, Hiroyuki Aoki, Katayoun Omidi, Daniel Burnside, Bahram Samanfar, Khaled A Aly, Ashkan Golshani, Mohan Babu

Nucleic Acids Res. 2021 Aug 20; 49(14): 8145–8160. Published online 2021 Jul 9. doi: 10.1093/nar/gkab585

PMCID:: PMC8373142

Abstract Article PDF–2.0M

Select item 75237067.

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis

Katrin Tiemann, Carolina Garri, Sang Bok Lee, Paymaneh D. Malihi, Mincheol Park, Ruth M. Alvarez, Li Peng Yap, Parag Mallick, Jonathan E. Katz, Mitchell E. Gross, Kian Kani

Oncogene. Author manuscript; available in PMC 2020 Sep 29.

Published in final edited form as: Oncogene. 2019 Apr; 38(16): 3003–3018. Published online 2018 Dec 21. doi: 10.1038/s41388-018-0638-9

PMCID:: PMC7523706

Abstract Article PDF–2.3M

Select item 74814048.

PARK2 promotes mitochondrial pathway of apoptosis and antimicrotubule drugs chemosensitivity via degradation of phospho-BCL-2

Hengxing Chen, Yun Li, Yu Li, Zhen Chen, Limin Xie, Wenjia Li, Yuanxin Zhu, Hong Xue, H. Phillip Koeffler, Wenjing Wu, Kaishun Hu, Dong Yin

Theranostics. 2020; 10(22): 9984–10000. Published online 2020 Aug 8. doi: 10.7150/thno.47044

PMCID:: PMC7481404

Abstract Article PDF–4.0M

Select item 67781379.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 673589210.

Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability

David Pladevall-Morera, Stephanie Munk, Andreas Ingham, Lorenza Garribba, Eliene Albers, Ying Liu, Jesper V Olsen, Andres J Lopez-Contreras

Nucleic Acids Res. 2019 Sep 5; 47(15): 8004–8018. Published online 2019 Jun 10. doi: 10.1093/nar/gkz510

Correction in:: Nucleic Acids Res. 2019 Sep 5; 47(15): 8332.

PMCID:: PMC6735892

Abstract Article PDF–5.4M

Select item 673379111.

CCT3 acts upstream of YAP and TFCP2 as a potential target and tumour biomarker in liver cancer

Ya Liu, Xiao Zhang, Jiafei Lin, Yuxin Chen, Yongxia Qiao, Susu Guo, Yueyue Yang, Guoqing Zhu, Qiuhui Pan, Jiayi Wang, Fenyong Sun

Cell Death Dis. 2019 Sep; 10(9): 644. Published online 2019 Sep 9. doi: 10.1038/s41419-019-1894-5

Correction in:: Cell Death Dis. 2022 Jul; 13(7): 598.

PMCID:: PMC6733791

Abstract Article PDF–3.3M

Select item 672167012.

Connecting the Dots in the Neuroglobin-Protein Interaction Network of an Unstressed and Ferroptotic Cell Death Neuroblastoma Model

Zoë P. Van Acker, Geert A. Van Raemdonck, Emilie Logie, Sara I. Van Acker, Geert Baggerman, Wim Vanden Berghe, Peter Ponsaerts, Sylvia Dewilde

Cells. 2019 Aug; 8(8): 873. Published online 2019 Aug 11. doi: 10.3390/cells8080873

PMCID:: PMC6721670

Abstract Article PDF–4.1M

Select item 650395213.

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing

Tiina Viita, Salla Kyheröinen, Bina Prajapati, Jori Virtanen, Mikko J. Frilander, Markku Varjosalo, Maria K. Vartiainen

J Cell Sci. 2019 Apr 15; 132(8): jcs226852. Published online 2019 Apr 17. doi: 10.1242/jcs.226852

PMCID:: PMC6503952

Abstract Article

Select item 648477214.

S100A3 a partner protein regulating the stability/activity of RARα and PML-RARα in cellular models of breast/lung cancer and acute myeloid leukemia

Maurizio Gianni, Mineko Terao, Mami Kurosaki, Gabriela Paroni, Laura Brunelli, Roberta Pastorelli, Adriana Zanetti, Monica Lupi, Andrea Acquavita, Marco Bolis, Maddalena Fratelli, Cecile Rochette-Egly, Enrico Garattini

Oncogene. 2019; 38(14): 2482–2500. Published online 2018 Dec 7. doi: 10.1038/s41388-018-0599-z

Correction in:: Oncogene. 2023; 42(3): 254–258.

PMCID:: PMC6484772

Abstract Article PDF–7.7M

Select item 602672615.

A Screen for Epstein-Barr Virus Proteins That Inhibit the DNA Damage Response Reveals a Novel Histone Binding Protein

Ting-Hin Ho, Justine Sitz, Qingtang Shen, Ariane Leblanc-Lacroix, Eric I. Campos, Ivan Borozan, Edyta Marcon, Jack Greenblatt, Amelie Fradet-Turcotte, Dong-Yan Jin, Lori Frappier

J Virol. 2018 Jul 15; 92(14): e00262-18. Prepublished online 2018 May 9. Published online 2018 Jun 29. doi: 10.1128/JVI.00262-18

PMCID:: PMC6026726

Abstract Article PDF–2.2M

Select item 599939616.

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation

Tyler B Faust, Yang Li, Curtis W Bacon, Gwendolyn M Jang, Amit Weiss, Bhargavi Jayaraman, Billy W Newton, Nevan J Krogan, Iván D'Orso, Alan D Frankel

eLife. 2018; 7: e31879. Published online 2018 May 30. doi: 10.7554/eLife.31879

PMCID:: PMC5999396

Abstract Article PDF–3.6M

Select item 582692617.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 572549418.

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair

Huiming Lu, Raghavendra A. Shamanna, Jessica K. de Freitas, Mustafa Okur, Prabhat Khadka, Tomasz Kulikowicz, Priscella P. Holland, Jane Tian, Deborah L. Croteau, Anthony J. Davis, Vilhelm A. Bohr

Nat Commun. 2017; 8: 2039. Published online 2017 Dec 11. doi: 10.1038/s41467-017-02146-3

PMCID:: PMC5725494

Abstract Article PDF–4.0M

Select item 559224419.

Wnt-Dependent Inactivation of the Groucho/TLE Co-repressor by the HECT E3 Ubiquitin Ligase Hyd/UBR5

Joshua E. Flack, Juliusz Mieszczanek, Nikola Novcic, Mariann Bienz

Mol Cell. 2017 Jul 20; 67(2): 181–193.e5. doi: 10.1016/j.molcel.2017.06.009

PMCID:: PMC5592244

Abstract Article

Select item 465610820.

Analysis of the Histone H3.1 Interactome: A Suitable Chaperone for the Right Event

Eric I. Campos, Arne H. Smits, Young-Hoon Kang, Sébastien Landry, Thelma M. Escobar, Shruti Nayak, Beatrix M. Ueberheide, Daniel Durocher, Michiel Vermeulen, Jerard Hurwitz, Danny Reinberg

Mol Cell. Author manuscript; available in PMC 2016 Nov 19.

Published in final edited form as: Mol Cell. 2015 Nov 19; 60(4): 697–709. Published online 2015 Oct 29. doi: 10.1016/j.molcel.2015.08.005