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Select item 114149811.

Histone variant H2A.Z is needed for efficient transcription-coupled NER and genome integrity in UV challenged yeast cells

Hélène Gaillard, Toni Ciudad, Andrés Aguilera, Ralf E. Wellinger

PLoS Genet. 2024 Sep; 20(9): e1011300. Published online 2024 Sep 10. doi: 10.1371/journal.pgen.1011300

PMCID:: PMC11414981

Abstract Article PDF–2.9M

Select item 107001382.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 102333683.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 102130504.

Bre1/RNF20 promotes Rad51-mediated strand exchange and antagonizes the Srs2/FBH1 helicases

Guangxue Liu, Jimin Li, Boxue He, Jiaqi Yan, Jingyu Zhao, Xuejie Wang, Xiaocong Zhao, Jingyan Xu, Yeyao Wu, Simin Zhang, Xiaoli Gan, Chun Zhou, Xiangpan Li, Xinghua Zhang, Xuefeng Chen

Nat Commun. 2023; 14: 3024. Published online 2023 May 25. doi: 10.1038/s41467-023-38617-z

PMCID:: PMC10213050

Abstract Article PDF–1.3M

Select item 99845325.

Genetic requirements for repair of lesions caused by single genomic ribonucleotides in S phase

Natalie Schindler, Matthias Tonn, Vanessa Kellner, Jia Jun Fung, Arianna Lockhart, Olga Vydzhak, Thomas Juretschke, Stefanie Möckel, Petra Beli, Anton Khmelinskii, Brian Luke

Nat Commun. 2023; 14: 1227. Published online 2023 Mar 3. doi: 10.1038/s41467-023-36866-6

PMCID:: PMC9984532

Abstract Article PDF–3.0M

Select item 99374896.

Rad51 filaments assembled in the absence of the complex formed by the Rad51 paralogs Rad55 and Rad57 are outcompeted by translesion DNA polymerases on UV-induced ssDNA gaps

Laurent Maloisel, Emilie Ma, Jamie Phipps, Alice Deshayes, Stefano Mattarocci, Stéphane Marcand, Karine Dubrana, Eric Coïc

PLoS Genet. 2023 Feb; 19(2): e1010639. Published online 2023 Feb 7. doi: 10.1371/journal.pgen.1010639

PMCID:: PMC9937489

Abstract Article PDF–2.6M

Select item 96309867.

A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans

Phoebe Y T Lu, Alyssa C Kirlin, Maria J Aristizabal, Hilary T Brewis, Nancy Lévesque, Dheva T Setiaputra, Nikita Avvakumov, Joris J Benschop, Marian Groot Koerkamp, Frank C P Holstege, Nevan J Krogan, Calvin K Yip, Jacques Côté, Michael S Kobor

Genetics. 2022 Nov; 222(3): iyac136. Published online 2022 Sep 6. doi: 10.1093/genetics/iyac136

PMCID:: PMC9630986

Abstract Article PDF–2.2M

Select item 92098118.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 87489889.

Mechanism for inverted-repeat recombination induced by a replication fork barrier

Léa Marie, Lorraine S. Symington

Nat Commun. 2022; 13: 32. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27443-w

PMCID:: PMC8748988

Abstract Article PDF–24M

Select item 847222210.

The Role of the Rad55–Rad57 Complex in DNA Repair

Upasana Roy, Eric C. Greene

Genes (Basel) 2021 Sep; 12(9): 1390. Published online 2021 Sep 8. doi: 10.3390/genes12091390

PMCID:: PMC8472222

Abstract Article PDF–849K

Select item 826240511.

The Rad51 paralog complex Rad55-Rad57 acts as a molecular chaperone during homologous recombination

Upasana Roy, Youngho Kwon, Lea Marie, Lorraine Symington, Patrick Sung, Michael Lisby, Eric C. Greene

Mol Cell. Author manuscript; available in PMC 2022 Mar 4.

Published in final edited form as: Mol Cell. 2021 Mar 4; 81(5): 1043–1057.e8. Published online 2021 Jan 8. doi: 10.1016/j.molcel.2020.12.019

PMCID:: PMC8262405

Abstract Article PDF–3.0M

Select item 804059812.

Modeling DNA trapping of anticancer therapeutic targets using missense mutations identifies dominant synthetic lethal interactions

Akil Hamza, Leanne Amitzi, Lina Ma, Maureen R. M. Driessen, Nigel J. O'Neil, Philip Hieter

Proc Natl Acad Sci U S A. 2021 Apr 6; 118(14): e2100240118. Published online 2021 Mar 29. doi: 10.1073/pnas.2100240118

PMCID:: PMC8040598

Abstract Article PDF–1.5M

Select item 771875113.

Comprehensive Synthetic Genetic Array Analysis of Alleles That Interact with Mutation of the Saccharomyces cerevisiae RecQ Helicases Hrq1 and Sgs1

Elsbeth Sanders, Phoebe A. Nguyen, Cody M. Rogers, Matthew L. Bochman

G3 (Bethesda) 2020 Dec; 10(12): 4359–4368. Published online 2020 Oct 28. doi: 10.1534/g3.120.401709

PMCID:: PMC7718751

Abstract Article PDF–1.2M

Select item 692775014.

Distinct roles for S. cerevisiae H2A copies in recombination and repeat stability, with a role for H2A.1 threonine 126

Nealia CM House, Erica J Polleys, Ishtiaque Quasem, Marjorie De la Rosa Mejia, Cailin E Joyce, Oliver Takacsi-Nagy, Jocelyn E Krebs, Stephen M Fuchs, Catherine H Freudenreich

eLife. 2019; 8: e53362. Published online 2019 Dec 5. doi: 10.7554/eLife.53362

PMCID:: PMC6927750

Abstract Article PDF–3.2M

Select item 675347115.

Rad5 dysregulation drives hyperactive recombination at replication forks resulting in cisplatin sensitivity and genome instability

Eric E Bryant, Ivana Šunjevarić, Luke Berchowitz, Rodney Rothstein, Robert J D Reid

Nucleic Acids Res. 2019 Sep 26; 47(17): 9144–9159. Published online 2019 Jul 27. doi: 10.1093/nar/gkz631

PMCID:: PMC6753471

Abstract Article PDF–6.0M

Select item 656384116.

Quantitative assessment of changes in cell growth, size and morphology during telomere-initiated cellular senescence in Saccharomyces cerevisiae

Neda Z. Ghanem, Shubha R. L. Malla, Naoko Araki, L. Kevin Lewis

Exp Cell Res. Author manuscript; available in PMC 2020 Aug 1.

Published in final edited form as: Exp Cell Res. 2019 Aug 1; 381(1): 18–28. Published online 2019 May 7. doi: 10.1016/j.yexcr.2019.05.005

PMCID:: PMC6563841

Abstract Article PDF–1.3M

Select item 621571317.

Systematic Analysis of Complex Genetic Interactions

Elena Kuzmin, Benjamin VanderSluis, Wen Wang, Guihong Tan, Raamesh Deshpande, Yiqun Chen, Matej Usaj, Attila Balint, Mojca Mattiazzi Usaj, Jolanda van Leeuwen, Elizabeth N. Koch, Carles Pons, Andrius J. Dagilis, Michael Pryszlak, Jason Zi Yang Wang, Julia Hanchard, Margot Riggi, Kaicong Xu, Hamed Heydari, Bryan-Joseph San Luis, Ermira Shuteriqi, Hongwei Zhu, Nydia Van Dyk, Sara Sharifpoor, Michael Costanzo, Robbie Loewith, Amy Caudy, Daniel Bolnick, Grant W. Brown, Brenda J. Andrews, Charles Boone, Chad L. Myers

Science. Author manuscript; available in PMC 2018 Nov 4.

Published in final edited form as: Science. 2018 Apr 20; 360(6386): eaao1729. doi: 10.1126/science.aao1729

PMCID:: PMC6215713

Abstract Article PDF–1.9M

Select item 597451218.

Mapping DNA damage‐dependent genetic interactions in yeast via party mating and barcode fusion genetics

J Javier Díaz‐Mejía, Albi Celaj, Joseph C Mellor, Atina Coté, Attila Balint, Brandon Ho, Pritpal Bansal, Fatemeh Shaeri, Marinella Gebbia, Jochen Weile, Marta Verby, Anna Karkhanina, YiFan Zhang, Cassandra Wong, Justin Rich, D'Arcy Prendergast, Gaurav Gupta, Sedide Öztürk, Daniel Durocher, Grant W Brown, Frederick P Roth

Mol Syst Biol. 2018 May; 14(5): e7985. Published online 2018 May 28. doi: 10.15252/msb.20177985

PMCID:: PMC5974512

Abstract Article PDF–2.2M

Select item 594015319.

Tight Regulation of Srs2 Helicase Activity Is Crucial for Proper Functioning of DNA Repair Mechanisms

Alex Bronstein, Shay Bramson, Keren Shemesh, Batia Liefshitz, Martin Kupiec

G3 (Bethesda) 2018 May; 8(5): 1615–1626. Published online 2018 Mar 12. doi: 10.1534/g3.118.200181

PMCID:: PMC5940153

Abstract Article PDF–1.3M

Select item 592252820.

Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs

Harley O’Connor Mount, Nicole M. Revie, Robert T. Todd, Kaitlin Anstett, Cathy Collins, Michael Costanzo, Charles Boone, Nicole Robbins, Anna Selmecki, Leah E. Cowen

PLoS Genet. 2018 Apr; 14(4): e1007319. Published online 2018 Apr 27. doi: 10.1371/journal.pgen.1007319

PMCID:: PMC5922528

Abstract Article PDF–7.1M

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