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Items: 1 to 20 of 80

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
A Novel Mouse Model for SNP in Steroid Receptor Co-Activator-1 Reveals Role in Bone Density and Breast Cancer Metastasis
Rebecca J Watters, Kostas Verdelis, Peter C Lucas, Shiming Jiang, Yuqing Chen, Feiqi Lu, Benjamin M Martin, Lyuda Lukashova, Geoffrey Pecar, Alejandro Morales-Restrepo, Margaret Hankins, Li Zhu, Peter Mittwede, Ryan J Hartmaier, Peter G Alexander, George C Tseng, Kurt R Weiss, Deborah L Galson, Adrian V Lee, Brendan Lee, Steffi Oesterreich
Endocrinology. 2021 Aug; 162(8): bqab094. Published online 2021 May 7. doi: 10.1210/endocr/bqab094
PMCID:
PMC8248588
AbstractArticle
3.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
4.
Interleukin-13 receptor subunit alpha-2 is a target of progesterone receptor and steroid receptor coactivator-1 in the mouse uterus
Ryan M Marquardt, Kevin Lee, Tae Hoon Kim, Brandon Lee, Francesco J DeMayo, Jae-Wook Jeong
Biol Reprod. 2020 Oct; 103(4): 760–768. Published online 2020 Jun 19. doi: 10.1093/biolre/ioaa110
PMCID:
PMC7569349
AbstractArticlePDF–1.1M
5.
SRC-1 Null Mice Exhibit Moderate Motor Dysfunction and Delayed Development of Cerebellar Purkinje Cells
Eijun Nishihara, Hiromi Yoshida-Komiya, Chi-Shing Chan, Lan Liao, Ronald L. Davis, Bert W. O'Malley, Jianming Xu
J Neurosci. 2003 Jan 1; 23(1): 213–222. doi: 10.1523/JNEUROSCI.23-01-00213.2003
PMCID:
PMC6742154
AbstractArticlePDF–641K
6.
Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis
Yongjie Yang, Agatha A. van der Klaauw, Liangru Zhu, Tessa M. Cacciottolo, Yanlin He, Lukas K. J. Stadler, Chunmei Wang, Pingwen Xu, Kenji Saito, Antentor Hinton, Jr., Xiaofeng Yan, Julia M. Keogh, Elana Henning, Matthew C. Banton, Audrey E. Hendricks, Elena G. Bochukova, Vanisha Mistry, Katherine L. Lawler, Lan Liao, Jianming Xu, Stephen O’Rahilly, Qingchun Tong, UK10K Consortium, Inês Barroso, Bert W. O’Malley, I. Sadaf Farooqi, Yong Xu
Nat Commun. 2019; 10: 1718. Published online 2019 Apr 12. doi: 10.1038/s41467-019-08737-6
PMCID:
PMC6461669
AbstractArticlePDF–1.3M
7.
Sumoylation of RORγt regulates TH17 differentiation and thymocyte development
Zhiheng He, Jing Zhang, Zhaofeng Huang, Qian Du, Ning Li, Qiang Zhang, Yuan Chen, Zuoming Sun
Nat Commun. 2018; 9: 4870. Published online 2018 Nov 19. doi: 10.1038/s41467-018-07203-z
PMCID:
PMC6242824
AbstractArticlePDF–3.3M
8.
Cloning and Identification of Mouse Steroid Receptor Coactivator-1 (mSRC-1), as a Coactivator of Peroxisome Proliferator-Activated Receptor γ
Yijun Zhu, Chao Qi, Carl Calandra, M. Sambasiva Rao, Janardan K. Reddy
Gene Expr. 1996; 6(3): 185–195. Published online 2018 Sep 21.
PMCID:
PMC6148307
AbstractArticlePDF–1.6M
9.
SRC1 promotes Th17 differentiation by overriding Foxp3 suppression to stimulate RORγt activity in a PKC-θ–dependent manner
Subha Sen, Fei Wang, Jing Zhang, Zhiheng He, Jian Ma, Yousang Gwack, Jianming Xu, Zuoming Sun
Proc Natl Acad Sci U S A. 2018 Jan 16; 115(3): E458–E467. Published online 2017 Dec 27. doi: 10.1073/pnas.1717789115
PMCID:
PMC5776998
AbstractArticlePDF–2.1M
10.
Nuclear Shp2 directs normal embryo implantation via facilitating the ERα tyrosine phosphorylation by the Src kinase
Hao Ran, Shuangbo Kong, Shuang Zhang, Jianghong Cheng, Chan Zhou, Bo He, Qiliang Xin, John P. Lydon, Francesco J. DeMayo, Gen-Sheng Feng, Guoliang Xia, Zhongxian Lu, Chao Wang, Haibin Wang
Proc Natl Acad Sci U S A. 2017 May 2; 114(18): 4816–4821. Published online 2017 Apr 19. doi: 10.1073/pnas.1700978114
PMCID:
PMC5422785
AbstractArticlePDF–1.3M
11.
SRC-1 Regulates Blood Pressure and Aortic Stiffness in Female Mice
Antentor Othrell Hinton, Jr, Yongjie Yang, Ann P. Quick, Pingwen Xu, Chitra L. Reddy, Xiaofeng Yan, Corey L. Reynolds, Qingchun Tong, Liangru Zhu, Jianming Xu, Xander H. T. Wehrens, Yong Xu, Anilkumar K. Reddy
PLoS One. 2016; 11(12): e0168644. Published online 2016 Dec 22. doi: 10.1371/journal.pone.0168644
PMCID:
PMC5179266
AbstractArticlePDF–1.6M
12.
p62/SQSTM1 by binding to vitamin D receptor inhibits hepatic stellate cell activity, fibrosis and liver cancer
Angeles Duran, Eloy D. Hernandez, Miguel Reina-Campos, Elias A. Castilla, Shankar Subramaniam, Sindhu Raghunandan, Lewis R. Roberts, Tatiana Kisseleva, Michael Karin, Maria T. Diaz-Meco, Jorge Moscat
Cancer Cell. Author manuscript; available in PMC 2017 Oct 10.
Published in final edited form as: Cancer Cell. 2016 Oct 10; 30(4): 595–609. doi: 10.1016/j.ccell.2016.09.004
PMCID:
PMC5081228
AbstractArticlePDF–1.9M
13.
Ubiquitination of RORγt at Lysine 446 Limits Th17 Differentiation by Controlling Co-activator Recruitment
Zhiheng He, Fei Wang, Jian Ma, Subha Sen, Jing Zhang, Yousang Gwack, Yu Zhou, Zuoming Sun
J Immunol. Author manuscript; available in PMC 2017 Aug 15.
Published in final edited form as: J Immunol. 2016 Aug 15; 197(4): 1148–1158. Published online 2016 Jul 18. doi: 10.4049/jimmunol.1600548
PMCID:
PMC4976012
AbstractArticlePDF–1.9M
14.
Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition
Lu Gao, Elizabeth H. Rabbitt, Jennifer C. Condon, Nora E. Renthal, John M. Johnston, Matthew A. Mitsche, Pierre Chambon, Jianming Xu, Bert W. O’Malley, Carole R. Mendelson
J Clin Invest. 2015 Jul 1; 125(7): 2808–2824. Published online 2015 Jun 22. doi: 10.1172/JCI78544
PMCID:
PMC4563678
AbstractArticlePDF–3.5M
15.
Knockout of SRC-1 and SRC-3 in Mice Decreases Cardiomyocyte Proliferation and Causes a Noncompaction Cardiomyopathy Phenotype
Xian Chen, Li Qin, Zhaoliang Liu, Lan Liao, James F. Martin, Jianming Xu
Int J Biol Sci. 2015; 11(9): 1056–1072. Published online 2015 Jul 15. doi: 10.7150/ijbs.12408
PMCID:
PMC4515817
AbstractArticlePDF–2.5M
16.
A high resolution spatiotemporal atlas of gene expression of the developing mouse brain
Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones
Neuron. Author manuscript; available in PMC 2015 Jul 16.
Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033
PMCID:
PMC4319559
AbstractArticlePDF–3.0M
17.
Increased gene copy number of the vesicle SNARE VAMP7 disrupts human male urogenital development through altered estrogen action
Mounia Tannour-Louet, Shuo Han, Jean-Francois Louet, Bin Zhang, Karina Romero, Josephine Addai, Aysegul Sahin, Sau Wai Cheung, Dolores J Lamb
Nat Med. Author manuscript; available in PMC 2015 Jan 5.
Published in final edited form as: Nat Med. 2014 Jul; 20(7): 715–724. Published online 2014 Jun 1. doi: 10.1038/nm.3580
PMCID:
PMC4283218
AbstractArticlePDF–3.1M
18.
Hepatic SRC-1 Activity Orchestrates Transcriptional Circuitries of Amino Acid Pathways with Potential Relevance for Human Metabolic Pathogenesis
Mounia Tannour-Louet, Brian York, Ke Tang, Erin Stashi, Hichem Bouguerra, Suoling Zhou, Hui Yu, Lee-Jun C. Wong, Robert D. Stevens, Jianming Xu, Christopher B. Newgard, Bert W. O'Malley, Jean-Francois Louet
Mol Endocrinol. 2014 Oct; 28(10): 1707–1718. Published online 2014 Aug 22. doi: 10.1210/me.2014-1083
PMCID:
PMC4179626
AbstractArticle
19.
A genomic atlas of mouse hypothalamic development
Tomomi Shimogori, Daniel A Lee, Ana Miranda-Angulo, Yanqin Yang, Hong Wang, Lizhi Jiang, Aya C Yoshida, Ayane Kataoka, Hiromi Mashiko, Marina Avetisyan, Lixin Qi, Jiang Qian, Seth Blackshaw
Nat Neurosci. Author manuscript; available in PMC 2014 Jun 24.
Published in final edited form as: Nat Neurosci. 2010 Jun; 13(6): 767–775. Published online 2010 May 2. doi: 10.1038/nn.2545
PMCID:
PMC4067769
AbstractArticlePDF–1.8M
20.
Steroid Receptor Coactivator-2 Is a Dual Regulator of Cardiac Transcription Factor Function
Erin L. Reineke, Ashley Benham, Benjamin Soibam, Erin Stashi, Heinrich Taegtmeyer, Mark L. Entman, Robert J. Schwartz, Bert W. O'Malley
J Biol Chem. 2014 Jun 20; 289(25): 17721–17731. Published online 2014 May 8. doi: 10.1074/jbc.M113.539908
PMCID:
PMC4067206
AbstractArticlePDF–1.8M

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