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Select item 112109131.

PRMT-7/PRMT7 activates HLH-30/TFEB to guard plasma membrane integrity compromised by bacterial pore-forming toxins

Hui-Chen Hsieh, I-Hsiang Huang, Shao-Wen Chang, Po-Lin Chen, Yu-Cheng Su, Shuying Wang, Wei-Jiun Tsai, Ping-Hung Chen, Raffi V. Aroian, Chang-Shi Chen

Autophagy. 2024; 20(6): 1335–1358. Published online 2024 Jan 23. doi: 10.1080/15548627.2024.2306655

PMCID:: PMC11210913

Abstract Article PDF–7.6M

Select item 110227502.

Autophagy protein ATG-16.2 and its WD40 domain mediate the beneficial effects of inhibiting early-acting autophagy genes in C. elegans neurons

Yongzhi Yang, Meghan Lee Arnold, Caitlin M. Lange, Ling-Hsuan Sun, Michael Broussalian, Saam Doroodian, Hiroshi Ebata, Elizabeth H. Choy, Karie Poon, Tatiana M. Moreno, Anupama Singh, Monica Driscoll, Caroline Kumsta, Malene Hansen

Nat Aging. Author manuscript; available in PMC 2024 Apr 17.

Published in final edited form as: Nat Aging. 2024 Feb; 4(2): 198–212. Published online 2024 Jan 4. doi: 10.1038/s43587-023-00548-1

PMCID:: PMC11022750

Abstract Article PDF–4.4M

Select item 110043423.

Phloretic acid requires the insulin/IGF-1 pathway and autophagy to enhance stress resistance and extend the lifespan of Caenorhabditis elegans

Bo Li, Li Dong, Wei Meng, Shi-Ying Xiong, Gui-Sheng Wu, Wen-Zhe Ma, Huai-Rong Luo

Front Pharmacol. 2024; 15: 1384227. Published online 2024 Mar 27. doi: 10.3389/fphar.2024.1384227

PMCID:: PMC11004342

Abstract Article PDF–3.0M

Select item 109147814.

Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B

Misaki Okahata, Natsumi Sawada, Kenji Nakao, Akane Ohta, Atsushi Kuhara

Sci Rep. 2024; 14: 5401. Published online 2024 Mar 5. doi: 10.1038/s41598-024-55794-z

PMCID:: PMC10914781

Abstract Article PDF–2.1M

Select item 108762125.

Organelle proteomic profiling reveals lysosomal heterogeneity in association with longevity

Yong Yu, Shihong M Gao, Youchen Guan, Pei-Wen Hu, Qinghao Zhang, Jiaming Liu, Bentian Jing, Qian Zhao, David M Sabatini, Monther Abu-Remaileh, Sung Yun Jung, Meng C Wang

eLife. 2024; 13: e85214. Published online 2024 Jan 19. doi: 10.7554/eLife.85214

PMCID:: PMC10876212

Abstract Article PDF–5.9M

Select item 105519026.

Lipid droplets modulate proteostasis, SQST-1/SQSTM1 dynamics, and lifespan in C. elegans

Anita V. Kumar, Joslyn Mills, Wesley M. Parker, Joshua A. Leitão, Diego I. Rodriguez, Sandrine E. Daigle, Celeste Ng, Rishi Patel, Joseph L. Aguilera, Joseph R. Johnson, Shi Quan Wong, Louis R. Lapierre

iScience. 2023 Oct 20; 26(10): 107960. Published online 2023 Sep 16. doi: 10.1016/j.isci.2023.107960

PMCID:: PMC10551902

Abstract Article PDF–4.6M

Select item 103450907.

Reprogramming of the transcriptome after heat stress mediates heat hormesis in Caenorhabditis elegans

Fan Xu, Ruoyao Li, Erika D. von Gromoff, Friedel Drepper, Bettina Knapp, Bettina Warscheid, Ralf Baumeister, Wenjing Qi

Nat Commun. 2023; 14: 4176. Published online 2023 Jul 13. doi: 10.1038/s41467-023-39882-8

PMCID:: PMC10345090

Abstract Article PDF–8.1M

Select item 101149218.

Lysosomal chloride transporter CLH-6 protects lysosome membrane integrity via cathepsin activation

Qianqian Zhang, Yuan Li, Youli Jian, Meijiao Li, Xiaochen Wang

J Cell Biol. 2023 Jun 5; 222(6): e202210063. Published online 2023 Apr 14. doi: 10.1083/jcb.202210063

PMCID:: PMC10114921

Abstract Article PDF–9.7M

Select item 98351509.

Detecting Autophagy in Caenorhabditis elegans Embryos Using Markers of P Granule Degradation

Nicholas J. Palmisano, Alicia Meléndez

Cold Spring Harb Protoc. Author manuscript; available in PMC 2023 Jan 12.

Published in final edited form as: Cold Spring Harb Protoc. 2016 Jan 4; 2016(1): pdb.prot086504. Published online 2016 Jan 4. doi: 10.1101/pdb.prot086504

PMCID:: PMC9835150

Abstract Article PDF–338K

Select item 980994810.

SAMS-1 coordinates HLH-30/TFEB and PHA-4/FOXA activities through histone methylation to mediate dietary restriction-induced autophagy and longevity

Chiao-Yin Lim, Huan-Ting Lin, Caroline Kumsta, Tzu-Chiao Lu, Feng-Yung Wang, Yun-Hsuan Kang, Malene Hansen, Tsui-Ting Ching, Ao-Lin Hsu

Autophagy. 2023; 19(1): 224–240. Published online 2022 May 3. doi: 10.1080/15548627.2022.2068267

PMCID:: PMC9809948

Abstract Article PDF–4.7M

Select item 964278011.

Cobalt chloride has beneficial effects across species through a hormetic mechanism

Alfonso Schiavi, Alessandra Runci, Teresa Maiorino, Francesco Davide Naso, Marta Barenys, Ellen Fritsche, Flavie Strappazzon, Natascia Ventura

Front Cell Dev Biol. 2022; 10: 986835. Published online 2022 Oct 25. doi: 10.3389/fcell.2022.986835

PMCID:: PMC9642780

Abstract Article PDF–1.7M

Select item 962984912.

Bidirectional regulation of structural damage on autophagy in the C. elegans epidermis

Rong Fu, Xiaowan Jiang, Yuyan Yang, Chunxia Wang, Yun Zhang, Yi Zhu, Huimin Zhang

Autophagy. 2022; 18(11): 2731–2745. Published online 2022 Mar 20. doi: 10.1080/15548627.2022.2047345

PMCID:: PMC9629849

Abstract Article PDF–3.0M

Select item 906508413.

Functional identification of microRNA-centered complexes in C. elegans

Shilpa Hebbar, Ganesh Panzade, Ajay A. Vashisht, James A. Wohlschlegel, Isana Veksler-Lublinsky, Anna Y. Zinovyeva

Sci Rep. 2022; 12: 7133. Published online 2022 May 3. doi: 10.1038/s41598-022-10771-2

PMCID:: PMC9065084

Abstract Article PDF–2.2M

Select item 866564514.

Variants in ATP6V0A1 cause progressive myoclonus epilepsy and developmental and epileptic encephalopathy

Laura C Bott, Mitra Forouhan, Maria Lieto, Ambre J Sala, Ruth Ellerington, Janel O Johnson, Alfina A Speciale, Chiara Criscuolo, Alessandro Filla, David Chitayat, Ebba Alkhunaizi, Patrick Shannon, Andrea H Nemeth, Italian Undiagnosed Diseases Network , Francesco Angelucci, Wooi Fang Lim, Pasquale Striano, Federico Zara, Ingo Helbig, Mikko Muona, Carolina Courage, Anna-Elina Lehesjoki, Samuel F Berkovic, ATPase Consortium , Kenneth H Fischbeck, Francesco Brancati, Richard I Morimoto, Matthew J A Wood, Carlo Rinaldi

Brain Commun. 2021; 3(4): fcab245. Published online 2021 Oct 18. doi: 10.1093/braincomms/fcab245

PMCID:: PMC8665645

Abstract Article PDF–1.2M

Select item 833118315.

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan, Thomas F Duchaine, Matthias Selbach, Fabio Piano, Kristin C Gunsalus

eLife. 2021; 10: e60833. Published online 2021 Jul 5. doi: 10.7554/eLife.60833

PMCID:: PMC8331183

Abstract Article PDF–8.5M

Select item 800402116.

Molecular Basis of Neuronal Autophagy in Ageing: Insights from Caenorhabditis elegans

Georgios Konstantinidis, Nektarios Tavernarakis

Cells. 2021 Mar; 10(3): 694. Published online 2021 Mar 21. doi: 10.3390/cells10030694

PMCID:: PMC8004021

Abstract Article PDF–1.0M

Select item 781612217.

NAD⁺ boosting reduces age-associated amyloidosis and restores mitochondrial homeostasis in muscle

Mario Romani, Vincenzo Sorrentino, Chang-Myung Oh, Hao Li, Tanes Imamura de Lima, Hongbo Zhang, Minho Shong, Johan Auwerx

Cell Rep. 2021 Jan 19; 34(3): 108660. Published online 2021 Jan 19. doi: 10.1016/j.celrep.2020.108660

PMCID:: PMC7816122

Abstract Article

Select item 768289018.

Natural variation in the sequestosome-related gene, sqst-5, underlies zinc homeostasis in Caenorhabditis elegans

Kathryn S. Evans, Stefan Zdraljevic, Lewis Stevens, Kimberly Collins, Robyn E. Tanny, Erik C. Andersen

PLoS Genet. 2020 Nov; 16(11): e1008986. Published online 2020 Nov 11. doi: 10.1371/journal.pgen.1008986

PMCID:: PMC7682890

Abstract Article PDF–2.5M

Select item 713819819.

The tissue- and developmental stage-specific involvement of autophagy genes in aggrephagy

Hui Zheng, Chongzhen Yuan, Hui Zhang, Yingyu Chen, Hong Zhang

Autophagy. 2020; 16(4): 589–599. Published online 2019 Jun 26. doi: 10.1080/15548627.2019.1632121

PMCID:: PMC7138198

Abstract Article PDF–3.1M

Select item 711689420.

The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress

Terytty Yang Li, Maroun Bou Sleiman, Hao Li, Arwen W. Gao, Adrienne Mottis, Alexis Maximilien Bachmann, Gaby El Alam, Xiaoxu Li, Ludger J. E. Goeminne, Kristina Schoonjans, Johan Auwerx

Nat Aging. Author manuscript; available in PMC 2021 Mar 13.

Published in final edited form as: Nat Aging. 2021 Feb; 1(2): 165–178. Published online 2021 Feb 8. doi: 10.1038/s43587-020-00025-z

PMCID:: PMC7116894

Abstract Article PDF–6.3M

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