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Links from GEO Profiles

Items: 1 to 20 of 38

1.
Deregulation of Mitochondrial Calcium Handling Due to Presenilin Loss Disrupts Redox Homeostasis and Promotes Neuronal Dysfunction
Kerry C. Ryan, Jocelyn T. Laboy, Kenneth R. Norman
Antioxidants (Basel) 2022 Sep; 11(9): 1642. Published online 2022 Aug 24. doi: 10.3390/antiox11091642
PMCID:
PMC9495597
AbstractArticlePDF–2.2M
2.
Increased mitochondrial calcium uptake and concomitant mitochondrial activity by presenilin loss promotes mTORC1 signaling to drive neurodegeneration
Kerry C. Ryan, Zahra Ashkavand, Shaarika Sarasija, Jocelyn T. Laboy, Rohan Samarakoon, Kenneth R. Norman
Aging Cell. 2021 Oct; 20(10): e13472. Published online 2021 Sep 9. doi: 10.1111/acel.13472
PMCID:
PMC8520713
AbstractArticlePDF–1.6M
3.
The GxGD Motif of Presenilin Contributes to Catalytic Function and Substrate Identification of γ-Secretase
Aya Yamasaki, Stefan Eimer, Masayasu Okochi, Agata Smialowska, Christoph Kaether, Ralf Baumeister, Christian Haass, Harald Steiner
J Neurosci. 2006 Apr 5; 26(14): 3821–3828. doi: 10.1523/JNEUROSCI.5354-05.2006
PMCID:
PMC6674133
AbstractArticlePDF–1.0M
4.
OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes
Woojin Kim, Ryan S. Underwood, Iva Greenwald, Daniel D. Shaye
Genetics. 2018 Oct; 210(2): 445–461. Published online 2018 Aug 17. doi: 10.1534/genetics.118.301307
PMCID:
PMC6216590
AbstractArticlePDF–1.4M
5.
Presenilin mutations deregulate mitochondrial Ca2+ homeostasis and metabolic activity causing neurodegeneration in Caenorhabditis elegans
Shaarika Sarasija, Jocelyn T Laboy, Zahra Ashkavand, Jennifer Bonner, Yi Tang, Kenneth R Norman
eLife. 2018; 7: e33052. Published online 2018 Jul 10. doi: 10.7554/eLife.33052
PMCID:
PMC6075864
AbstractArticlePDF–5.7M
6.
HOP-1 Presenilin Deficiency Causes a Late-Onset Notch Signaling Phenotype That Affects Adult Germline Function in Caenorhabditis elegans
Ipsita Agarwal, Cassandra Farnow, Joshua Jiang, Kyung-Sik Kim, Donna E. Leet, Ruth Z. Solomon, Valerie A. Hale, Caroline Goutte
Genetics. 2018 Feb; 208(2): 745–762. Published online 2017 Dec 13. doi: 10.1534/genetics.117.300605
PMCID:
PMC5788535
AbstractArticlePDF–1.8M
7.
Mutational re-modeling of di-aspartyl intramembrane proteases: uncoupling physiologically-relevant activities from those associated with Alzheimer’s disease
Anastasia P. Grigorenko, Youri K. Moliaka, Olga V. Plotnikova, Alexander Smirnov, Vera A. Nikishina, Andrey Y. Goltsov, Fedor Gusev, Tatiana V. Andreeva, Omar Nelson, Ilya Bezprozvanny, Evgeny I. Rogaev
Oncotarget. 2017 Oct 10; 8(47): 82006–82026. Published online 2017 May 30. doi: 10.18632/oncotarget.18299
PMCID:
PMC5669866
AbstractArticlePDF–10M
8.
Boundary cells restrict dystroglycan trafficking to control basement membrane sliding during tissue remodeling
Shelly TH McClatchey, Zheng Wang, Lara M Linden, Eric L Hastie, Lin Wang, Wanqing Shen, Alan Chen, Qiuyi Chi, David R Sherwood
eLife. 2016; 5: e17218. Published online 2016 Sep 23. doi: 10.7554/eLife.17218
PMCID:
PMC5061546
AbstractArticlePDF–5.4M
9.
Ubiquitin-mediated pathways in C. elegans.
Edward T Kipreos
WormBook. 2005 : 1–24. Published online 2005 Dec 1. doi: 10.1895/wormbook.1.36.1
PMCID:
PMC4781597
AbstractArticle
10.
Germline proliferation and its control.
Judith Kimble, Sarah L Crittenden
WormBook. 2005 : 1–14. Published online 2005 Aug 15. doi: 10.1895/wormbook.1.13.1
PMCID:
PMC4781503
AbstractArticle
11.
LIN-12/Notch signaling in C. elegans.
Iva Greenwald
WormBook. 2005 : 1–16. Published online 2005 Aug 8. doi: 10.1895/wormbook.1.10.1
PMCID:
PMC4781465
AbstractArticle
12.
Genetic suppression.
Jonathan Hodgkin
WormBook. 2005 : 1–13. Published online 2005 Dec 27. doi: 10.1895/wormbook.1.59.1
PMCID:
PMC4781008
AbstractArticle
13.
Genetic enhancers.
Robert K Herman, John Yochem
WormBook. 2005 : 1–11. Published online 2005 Sep 16. doi: 10.1895/wormbook.1.27.1
PMCID:
PMC4780930
AbstractArticle
14.
A γ-Secretase Independent Role for Presenilin in Calcium Homeostasis Impacts Mitochondrial Function and Morphology in Caenorhabditis elegans
Shaarika Sarasija, Kenneth R. Norman
Genetics. 2015 Dec; 201(4): 1453–1466. Published online 2015 Oct 21. doi: 10.1534/genetics.115.182808
PMCID:
PMC4676538
AbstractArticlePDF–5.5M
15.
Use of Caenorhabditis elegans as a model to study Alzheimer’s disease and other neurodegenerative diseases
Adanna G. Alexander, Vanessa Marfil, Chris Li
Front Genet. 2014; 5: 279. Published online 2014 Sep 5. doi: 10.3389/fgene.2014.00279
PMCID:
PMC4155875
AbstractArticlePDF–2.7M
16.
A role of the LIN-12/Notch signaling pathway in diversifying the non-striated egg-laying muscles in C. elegans
Jared J. Hale, Nirav M. Amin, Carolyn George, Zachary Via, Herong Shi, Jun Liu
Dev Biol. Author manuscript; available in PMC 2015 May 15.
Published in final edited form as: Dev Biol. 2014 May 15; 389(2): 137–148. Published online 2014 Feb 7. doi: 10.1016/j.ydbio.2014.02.001
PMCID:
PMC3981933
AbstractArticlePDF–1.3M
17.
Notch Signaling Inhibits Axon Regeneration
Rachid El Bejjani, Marc Hammarlund
Neuron. Author manuscript; available in PMC 2013 Jun 22.
Published in final edited form as: Neuron. 2012 Jan 26; 73(2): 268–278. doi: 10.1016/j.neuron.2011.11.017
PMCID:
PMC3690129
AbstractArticlePDF–1.6M
18.
LIN-12/Notch signaling instructs postsynaptic muscle arm development by regulating UNC-40/DCC and MADD-2 in Caenorhabditis elegans
Pengpeng Li, Kevin M Collins, Michael R Koelle, Kang Shen
eLife. 2013; 2: e00378. Published online 2013 Mar 19. doi: 10.7554/eLife.00378
PMCID:
PMC3601818
AbstractArticlePDF–4.9M
19.
Insights from Caenorhabditis elegans on the role of metals in neurodegenerative diseases
Ebany J. Martinez-Finley, Daiana Silva Avila, Sudipta Chakraborty, Michael Aschner
Metallomics. Author manuscript; available in PMC 2011 Sep 14.
Published in final edited form as: Metallomics. 2011 Mar; 3(3): 271–279. Published online 2011 Jan 6. doi: 10.1039/c0mt00064g
PMCID:
PMC3172965
AbstractArticlePDF–223K
20.
OrthoList: A Compendium of C. elegans Genes with Human Orthologs
Daniel D. Shaye, Iva Greenwald
PLoS One. 2011; 6(5): e20085. Published online 2011 May 25. doi: 10.1371/journal.pone.0020085
Correction in:
PLoS One. 2014; 9(1): 10.1371/annotation/f5ffb738-a176-4a43-b0e0-249cdea45fe0.
PMCID:
PMC3102077
AbstractArticlePDF–530K

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