PMC Links for GEO Profiles (Select 91612432) - PMC

Min Kim, Hyo‐Gyoung Kang, Shin Yup Lee, Hyung Cheol Lee, Eung Bae Lee, Yi Young Choi, Won Kee Lee, Sukki Cho, Guang Jin, Hyo‐Sung Jheon, Ji Woong Son, Myung‐Hoon Lee, Deuk Kju Jung, Seung Ick Cha, Chang Ho Kim, Young Mo Kang, Sin Kam, Tae Hoon Jung, Sanghoon Jheon, Jae Yong Park

Cancer Sci. 2010 Nov; 101(11): 2436–2442. Published online 2010 Jul 31. doi: 10.1111/j.1349-7006.2010.01699.x

PMCID:: PMC11159840

Abstract Article PDF–209K

Select item 111099574.

SIRT2 promotes base excision repair by transcriptionally activating OGG1 in an ATM/ATR-dependent manner

Anke Geng, Jiahui Sun, Huanyin Tang, Yang Yu, Xiyue Wang, Jingyuan Zhang, Xiaona Wang, Xiaoxiang Sun, Xiaofang Zhou, Neng Gao, Rong Tan, Zhu Xu, Ying Jiang, Zhiyong Mao

Nucleic Acids Res. 2024 May 22; 52(9): 5107–5120. Published online 2024 Mar 30. doi: 10.1093/nar/gkae190

PMCID:: PMC11109957

Abstract Article PDF–2.3M

Select item 108698005.

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation

Christopher B. Nelson, Samuel Rogers, Kaushik Roychoudhury, Yaw Sing Tan, Caroline J. Atkinson, Alexander P. Sobinoff, Christopher G. Tomlinson, Anton Hsu, Robert Lu, Eloise Dray, Michelle Haber, Jamie I. Fletcher, Anthony J. Cesare, Rashmi S. Hegde, Hilda A. Pickett

Nat Commun. 2024; 15: 1385. Published online 2024 Feb 15. doi: 10.1038/s41467-024-45683-4

PMCID:: PMC10869800

Abstract Article PDF–9.3M

Select item 107835096.

ATR phosphorylates DHX9 at serine 321 to suppress R-loop accumulation upon genotoxic stress

Mei-Yin Liu, Keng-Ru Lin, Yuh-Ling Chien, Bing-Ze Yang, Li-Yu Tsui, Hsueh-Ping Catherine Chu, Ching-Shyi Peter Wu

Nucleic Acids Res. 2024 Jan 11; 52(1): 204–222. Published online 2023 Nov 1. doi: 10.1093/nar/gkad973

PMCID:: PMC10783509

Abstract Article PDF–2.3M

Select item 106817457.

ADAR1 links R-loop homeostasis to ATR activation in replication stress response

Biao Zhang, Yi Li, Jieyou Zhang, Yuejiao Wang, Can Liang, Ting Lu, Chunyong Zhang, Ling Liu, Yan Qin, Jiahuan He, Xiangnan Zhao, Jia Yu, Jihui Hao, Jie Yang, Mulin Jun Li, Zhi Yao, Shuai Ma, Hui Cheng, Tao Cheng, Lei Shi

Nucleic Acids Res. 2023 Nov 27; 51(21): 11668–11687. Published online 2023 Oct 13. doi: 10.1093/nar/gkad839

PMCID:: PMC10681745

Abstract Article PDF–3.8M

Select item 105973988.

DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C

Marton Tibor Kovacs, Marie Vallette, Pauline Wiertsema, Florent Dingli, Damarys Loew, Guilherme Pedreira de Freitas Nader, Matthieu Piel, Raphael Ceccaldi

Mol Cell. 2023 Oct 19; 83(20): 3659–3668.e10. doi: 10.1016/j.molcel.2023.09.023

PMCID:: PMC10597398

Abstract Article

Select item 105418849.

Mild replication stress causes premature centriole disengagement via a sub-critical Plk1 activity under the control of ATR-Chk1

Devashish Dwivedi, Daniela Harry, Patrick Meraldi

Nat Commun. 2023; 14: 6088. Published online 2023 Sep 29. doi: 10.1038/s41467-023-41753-1

PMCID:: PMC10541884

Abstract Article PDF–9.6M

Select item 1053027110.

Long Noncoding RNA ZBED5-AS1 Facilitates Tumor Progression and Metastasis in Lung Adenocarcinoma via ZNF146/ATR/Chk1 Axis

Feng Jiang, Xiaolu Huang, Liqun Ling, Shiyi Tang, Huixin Zhou, Xueding Cai, Yumin Wang

Int J Mol Sci. 2023 Sep; 24(18): 13925. Published online 2023 Sep 10. doi: 10.3390/ijms241813925

PMCID:: PMC10530271

Abstract Article PDF–7.0M

Select item 1052936211.

ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms

Wendy Leung, Antoine Simoneau, Sneha Saxena, Jessica Jackson, Parasvi S. Patel, Mangsi Limbu, Alessandro Vindigni, Lee Zou

Cell Rep. Author manuscript; available in PMC 2023 Sep 27.

Published in final edited form as: Cell Rep. 2023 Jul 25; 42(7): 112792. Published online 2023 Jul 16. doi: 10.1016/j.celrep.2023.112792

PMCID:: PMC10529362

Abstract Article PDF–2.8M

Select item 1048478212.

Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk

Naomi Wilcox, Martine Dumont, Anna González-Neira, Sara Carvalho, Charles Joly Beauparlant, Marco Crotti, Craig Luccarini, Penny Soucy, Stéphane Dubois, Rocio Nuñez-Torres, Guillermo Pita, Eugene J. Gardner, Joe Dennis, M. Rosario Alonso, Nuria Álvarez, Caroline Baynes, Annie Claude Collin-Deschesnes, Sylvie Desjardins, Heiko Becher, Sabine Behrens, Manjeet K. Bolla, Jose E. Castelao, Jenny Chang-Claude, Sten Cornelissen, Thilo Dörk, Christoph Engel, Manuela Gago-Dominguez, Pascal Guénel, Andreas Hadjisavvas, Eric Hahnen, Mikael Hartman, Belén Herráez, SGBCC Investigators, Audrey Jung, Renske Keeman, Marion Kiechle, Jingmei Li, Maria A. Loizidou, Michael Lush, Kyriaki Michailidou, Mihalis I. Panayiotidis, Xueling Sim, Soo Hwang Teo, Jonathan P. Tyrer, Lizet E. van der Kolk, Cecilia Wahlström, Qin Wang, John R. B. Perry, Javier Benitez, Marjanka K. Schmidt, Rita K. Schmutzler, Paul D. P. Pharoah, Arnaud Droit, Alison M. Dunning, Anders Kvist, Peter Devilee, Douglas F. Easton, Jacques Simard

Nat Genet. 2023; 55(9): 1435–1439. Published online 2023 Aug 17. doi: 10.1038/s41588-023-01466-z

Correction in:: Nat Genet. 2023; 55(11): 2009.

PMCID:: PMC10484782

Abstract Article PDF–3.5M

Select item 1046820413.

A local ATR-dependent checkpoint pathway is activated by a site-specific replication fork block in human cells

Sana Ahmed-Seghir, Manisha Jalan, Helen E Grimsley, Aman Sharma, Shyam Twayana, Settapong T Kosiyatrakul, Christopher Thompson, Carl L Schildkraut, Simon N Powell

eLife. 2023; 12: RP87357. Published online 2023 Aug 30. doi: 10.7554/eLife.87357

PMCID:: PMC10468204

Abstract Article PDF–5.3M

Select item 1045018614.

Alteration of replication protein A binding mode on single-stranded DNA by NSMF potentiates RPA phosphorylation by ATR kinase

Yujin Kang, Ye Gi Han, Keon Woo Khim, Woo Gyun Choi, Min Kyung Ju, Kibeom Park, Kyeong Jin Shin, Young Chan Chae, Jang Hyun Choi, Hongtae Kim, Ja Yil Lee

Nucleic Acids Res. 2023 Aug 25; 51(15): 7936–7950. Published online 2023 Jun 28. doi: 10.1093/nar/gkad543

PMCID:: PMC10450186

Abstract Article PDF–1.6M

Select item 1032592515.

Replisome dysfunction upon inducible TIMELESS degradation synergizes with ATR inhibition to trigger replication catastrophe

Jinal A Patel, Camryn Zezelic, Julie Rageul, Joanne Saldanha, Arafat Khan, Hyungjin Kim

Nucleic Acids Res. 2023 Jul 7; 51(12): 6246–6263. Published online 2023 May 5. doi: 10.1093/nar/gkad363

PMCID:: PMC10325925

Abstract Article PDF–1.9M

Select item 1028187816.

The FBXO32/ATR/ATM axis acts as a molecular switch to control the sensitivity of osteosarcoma cells to irradiation through its regulation of EXO1 expression: FBXO32/ATR/ATM/EXO1 axis induces OS cells to anti-radiotherapy

Yao Lu, Panpan Huang, Yanli Li, Wenyu Liu, Jing Li, Rui Zhao, Haihua Feng, Ce Shi, Gaolu Cao

Acta Biochim Biophys Sin (Shanghai) 2023 May; 55(5): 842–852. Published online 2023 May 24. doi: 10.3724/abbs.2023049

PMCID:: PMC10281878

Abstract Article PDF–1.9M

Select item 1015161517.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 1007290618.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 992925719.

RNF126‐Mediated MRE11 Ubiquitination Activates the DNA Damage Response and Confers Resistance of Triple‐Negative Breast Cancer to Radiotherapy

Wenjing Liu, Min Zheng, Rou Zhang, Qiuyun Jiang, Guangshi Du, Yingying Wu, Chuanyu Yang, Fubing Li, Wei Li, Luzhen Wang, Jiao Wu, Lei Shi, Wenhui Li, Kai Zhang, Zhongmei Zhou, Rong Liu, Yingzheng Gao, Xinwei Huang, Songqing Fan, Xu Zhi, Dewei Jiang, Ceshi Chen

Adv Sci (Weinh) 2023 Feb; 10(5): 2203884. Published online 2022 Dec 23. doi: 10.1002/advs.202203884

PMCID:: PMC9929257

Abstract Article PDF–6.3M

Select item 990432320.

The “extreme phenotype approach” applied to male breast cancer allows the identification of rare variants of ATR as potential breast cancer susceptibility alleles

Martin Chevarin, Diana Alcantara, Juliette Albuisson, Marie-Agnès Collonge-Rame, Céline Populaire, Zohair Selmani, Amandine Baurand, Caroline Sawka, Geoffrey Bertolone, Patrick Callier, Yannis Duffourd, Philippe Jonveaux, Yves-Jean Bignon, Isabelle Coupier, François Cornelis, Christophe Cordier, Monique Mozelle-Nivoix, Jean-Baptiste Rivière, Paul Kuentz, Christel Thauvin, Romain Boidot, François Ghiringhelli, Marc O'Driscoll, Laurence Faivre, Sophie Nambot

Oncotarget. 2023; 14: 111–125. Published online 2023 Feb 7. doi: 10.18632/oncotarget.28358

PMCID:: PMC9904323

Abstract Article PDF–1.5M

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