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Select item 114941791.

Interplay between acetylation and ubiquitination controls PSAT1 protein stability in lung adenocarcinoma

Yuhan Liu, Wenze Xun, Tao Zhao, Menglin Huang, Longhua Sun, Guilan Wen, Xiuhua Kang, Jianbin Wang, Tianyu Han

Commun Biol. 2024; 7: 1365. Published online 2024 Oct 21. doi: 10.1038/s42003-024-07051-2

PMCID:: PMC11494179

Abstract Article PDF–7.9M

Select item 114764012.

PSAT1 is upregulated by METTL3 to attenuate high glucose-induced retinal pigment epithelial cell apoptosis and oxidative stress

Xiaofeng Du, Yanting Wang, Fan Gao

Diagn Pathol. 2024; 19: 138. Published online 2024 Oct 15. doi: 10.1186/s13000-024-01556-4

PMCID:: PMC11476401

Abstract Article PDF–6.8M

Select item 113524153.

PSAT1 Promotes Metastasis via p-AKT/SP1/ITGA2 Axis in Estrogen Receptor-Negative Breast Cancer Cell

Xingda Zhang, Siyu Wang, Wei Li, Jianyu Wang, Yajie Gong, Quanrun Chen, Shihan Cao, Da Pang, Song Gao

Biomolecules. 2024 Aug; 14(8): 990. Published online 2024 Aug 12. doi: 10.3390/biom14080990

PMCID:: PMC11352415

Abstract Article PDF–21M

Select item 112099354.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 104523555.

Phosphoserine Aminotransferase Pathogenetic Variants in Serine Deficiency Disorders: A Functional Characterization

Francesco Marchesani, Annalisa Michielon, Elisabetta Viale, Annalisa Bianchera, Davide Cavazzini, Loredano Pollegioni, Giulia Murtas, Andrea Mozzarelli, Stefano Bettati, Alessio Peracchi, Barbara Campanini, Stefano Bruno

Biomolecules. 2023 Aug; 13(8): 1219. Published online 2023 Aug 4. doi: 10.3390/biom13081219

PMCID:: PMC10452355

Abstract Article PDF–2.0M

Select item 103176016.

Exosomal ERBB2IP contributes to tumor growth via elevating PSAT1 expression in non‐small cell lung carcinoma

Xijuan Peng, Lanfu Zhao, Linong Yao, Jingzhi Dong, Wei Wu, Tao Luo

Thorac Cancer. 2023 Jul; 14(19): 1812–1823. Published online 2023 May 16. doi: 10.1111/1759-7714.14926

PMCID:: PMC10317601

Abstract Article PDF–5.8M

Select item 102374227.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 102021838.

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage

Fengli Wang, Lingjuan Wang, Shiming Gan, Shenglei Feng, Sijin Ouyang, Xiaoli Wang, Shuiqiao Yuan

Research (Wash D C) 2023; 6: 0091. Published online 2023 Apr 12. doi: 10.34133/research.0091

PMCID:: PMC10202183

Abstract Article PDF–18M

Select item 101516159.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 1003123510.

L‐serine biosynthesis in the human central nervous system: Structure and function of phosphoserine aminotransferase

Francesco Marchesani, Erika Zangelmi, Giulia Murtas, Elisa Costanzi, Raheem Ullah, Alessio Peracchi, Stefano Bruno, Loredano Pollegioni, Andrea Mozzarelli, Paola Storici, Barbara Campanini

Protein Sci. 2023 Apr; 32(4): e4609. Published online 2023 Apr 1. doi: 10.1002/pro.4609

PMCID:: PMC10031235

Abstract Article PDF–7.6M

Select item 1000856511.

Downregulation of PSAT1 inhibits cell proliferation and migration in uterine corpus endometrial carcinoma

Min Wang, Song Yue, Zhu Yang

Sci Rep. 2023; 13: 4081. Published online 2023 Mar 11. doi: 10.1038/s41598-023-31325-0

PMCID:: PMC10008565

Abstract Article PDF–7.0M

Select item 992907112.

Targeting PSAT1 to mitigate metastasis in tumors with p53-72Pro variant

Jingwen Jiang, Hai-Ning Chen, Ping Jin, Li Zhou, Liyuan Peng, Zhao Huang, Siyuan Qin, Bowen Li, Hui Ming, Maochao Luo, Na Xie, Wei Gao, Edouard C. Nice, Qiang Yu, Canhua Huang

Signal Transduct Target Ther. 2023; 8: 65. Published online 2023 Feb 15. doi: 10.1038/s41392-022-01266-7

PMCID:: PMC9929071

Abstract Article PDF–7.3M

Select item 985197313.

A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets

Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I. Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, Savaş Tay, Glenn Randall, Peihui Wang, John T. Lis, Cédric Feschotte, Serpil C. Erzurum, Feixiong Cheng, Haiyuan Yu

Nat Biotechnol. Author manuscript; available in PMC 2023 Jan 20.

Published in final edited form as: Nat Biotechnol. 2023 Jan; 41(1): 128–139. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01474-0

PMCID:: PMC9851973

Abstract Article PDF–4.0M

Select item 948193314.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 927928515.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 927594716.

Examination of the effects of microRNA-145-5p and phosphoserine aminotransferase 1 in colon cancer

Ruliang Ding, Weiwen Hong, Liang Huang, Jinfan Shao, Wenfeng Yu, Xijuan Xu

Bioengineered. 2022; 13(5): 12794–12806. Published online 2022 May 26. doi: 10.1080/21655979.2022.2071010

PMCID:: PMC9275947

Abstract Article PDF–2.6M

Select item 921632617.

Serine Biosynthesis Is a Metabolic Vulnerability in IDH2-Driven Breast Cancer Progression

Georgina D. Barnabas, Joo Sang Lee, Tamar Shami, Michal Harel, Lir Beck, Michael Selitrennik, Livnat Jerby-Arnon, Neta Erez, Eytan Ruppin, Tamar Geiger

Cancer Res. Author manuscript; available in PMC 2022 Jun 22.

Published in final edited form as: Cancer Res. 2021 Mar 15; 81(6): 1443–1456. Published online 2021 Jan 26. doi: 10.1158/0008-5472.CAN-19-3020

PMCID:: PMC9216326

Abstract Article PDF–2.6M

Select item 917141118.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 911973619.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 910272620.

VCP interaction with HMGB1 promotes hepatocellular carcinoma progression by activating the PI3K/AKT/mTOR pathway

Zhangya Pu, Dan G. Duda, Yuanyuan Zhu, Siya Pei, Xiaofang Wang, Yan Huang, Panpan Yi, Zebing Huang, Fang Peng, Xingwang Hu, Xuegong Fan

J Transl Med. 2022; 20: 212. Published online 2022 May 13. doi: 10.1186/s12967-022-03416-5

PMCID:: PMC9102726

Abstract Article PDF–15M

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