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Select item 101577261.

Selective ablation of TRA-1-60⁺ pluripotent stem cells suppresses tumor growth of prostate cancer

Jordan M. White, Nicholas Ramos, Allen-Dexter Saliganan, Joon-Yong Chung, Meghan Bell, Jacob Lindquist, Kayla Conner, Wendy N. Wiesend, Michael Schopperle, Steve M. Patrick, Seongho Kim, Elisabeth I. Heath, Freddy E. Escorcia, Nerissa T. Viola

Theranostics. 2023; 13(7): 2057–2071. Published online 2023 Mar 27. doi: 10.7150/thno.78915

PMCID:: PMC10157726

Abstract Article PDF–7.1M

Select item 83526642.

Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein

Priyanka Chaurasia, Thi H.O. Nguyen, Louise C. Rowntree, Jennifer A. Juno, Adam K. Wheatley, Stephen J. Kent, Katherine Kedzierska, Jamie Rossjohn, Jan Petersen

J Biol Chem. 2021 Sep; 297(3): 101065. Published online 2021 Aug 10. doi: 10.1016/j.jbc.2021.101065

PMCID:: PMC8352664

Abstract Article PDF–2.3M

Select item 83071943.

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation

Sun-Ok Kim, Kyoung Sang Cho, Bo Yeon Kim, Kyung Ho Lee

Int J Mol Sci. 2021 Jul; 22(14): 7572. Published online 2021 Jul 15. doi: 10.3390/ijms22147572

PMCID:: PMC8307194

Abstract Article PDF–2.8M

Select item 79490584.

T cell receptor–dependent S-acylation of ZAP-70 controls activation of T cells

Ritika Tewari, Bieerkehazhi Shayahati, Ying Fan, Askar M. Akimzhanov

J Biol Chem. 2021 Jan-Jun; 296: 100311. Published online 2021 Jan 19. doi: 10.1016/j.jbc.2021.100311

PMCID:: PMC7949058

Abstract Article PDF–1.2M

Select item 76571795.

Genome‐wide association study of chemotherapeutic agent‐induced severe neutropenia/leucopenia for patients in Biobank Japan

Siew‐Kee Low, Suyoun Chung, Atsushi Takahashi, Hitoshi Zembutsu, Taisei Mushiroda, Michiaki Kubo, Yusuke Nakamura

Cancer Sci. 2013 Aug; 104(8): 1074–1082. Published online 2013 Jun 10. doi: 10.1111/cas.12186

PMCID:: PMC7657179

Abstract Article PDF–225K

Select item 74501196.

T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4

Charlotte H. Coles, Catriona McMurran, Angharad Lloyd, Miriam Hock, Linda Hibbert, Marine C. C. Raman, Conor Hayes, Patrick Lupardus, David K. Cole, Stephen Harper

J Biol Chem. 2020 Aug 14; 295(33): 11486–11494. Published online 2020 Jun 12. doi: 10.1074/jbc.RA120.014016

PMCID:: PMC7450119

Abstract Article PDF–1.9M

Select item 69833257.

Genome-wide CRISPR-Cas9 Screening Reveals Ubiquitous T cell Cancer Targeting via the monomorphic MHC class I related protein MR1

Michael D. Crowther, Garry Dolton, Mateusz Legut, Marine E. Caillaud, Angharad Lloyd, Meriem Attaf, Sarah A. E. Galloway, Cristina Rius, Colin P. Farrell, Barbara Szomolay, Ann Ager, Alan L. Parker, Anna Fuller, Marco Donia, James McCluskey, Jamie Rossjohn, Inge Marie Svane, John Phillips, Andrew K. Sewell

Nat Immunol. Author manuscript; available in PMC 2020 Jul 20.

Published in final edited form as: Nat Immunol. 2020 Feb; 21(2): 178–185. Published online 2020 Jan 20. doi: 10.1038/s41590-019-0578-8

PMCID:: PMC6983325

Abstract Article PDF–2.8M

Select item 69825858.

Geometrical characterization of T cell receptor binding modes reveals class-specific binding to maximize access to antigen

Nishant K. Singh, Esam T. Abualrous, Cory M. Ayres, Frank Noé, Ragul Gowthaman, Brian G. Pierce, Brian M. Baker

Proteins. Author manuscript; available in PMC 2021 Mar 1.

Published in final edited form as: Proteins. 2020 Mar; 88(3): 503–513. Published online 2019 Oct 21. doi: 10.1002/prot.25829

PMCID:: PMC6982585

Abstract Article PDF–1.6M

Select item 68569889.

Alexandra Laberko, Elvira Sultanova, Elena Gutovskaya, Irina Shipitsina, Larisa Shelikhova, Elena Kurnikova, Yakov Muzalevskii, Alexei Kazachenok, Dmitriy Pershin, Kirill Voronin, Anna Shcherbina, Michael Maschan, Alexey Maschan, Dmitry Balashov

Blood. 2019 Nov 14; 134(20): 1755–1763. Prepublished online 2019 Sep 26. doi: 10.1182/blood.2019001757

PMCID:: PMC6856988

Abstract Article

Select item 603622310.

ER-resident protein 46 (ERp46) triggers the mannose-trimming activity of ER degradation–enhancing α-mannosidase–like protein 3 (EDEM3)

Shangyu Yu, Shinji Ito, Ikuo Wada, Nobuko Hosokawa

J Biol Chem. 2018 Jul 6; 293(27): 10663–10674. Published online 2018 May 21. doi: 10.1074/jbc.RA118.003129

PMCID:: PMC6036223

Abstract Article PDF–2.4M

Select item 568318711.

Structural basis for clonal diversity of the human T-cell response to a dominant influenza virus epitope

Xinbo Yang, Guobing Chen, Nan-ping Weng, Roy A. Mariuzza

J Biol Chem. 2017 Nov 10; 292(45): 18618–18627. Published online 2017 Sep 20. doi: 10.1074/jbc.M117.810382

PMCID:: PMC5683187

Abstract Article PDF–1.7M

Select item 557068012.

TCR-CXCR4 signaling stabilizes cytokine mRNA transcripts via a PREX1-Rac1 pathway: implications for CTCL

Kimberly N. Kremer, Brittney A. Dinkel, Rosalie M. Sterner, Douglas G. Osborne, Dragan Jevremovic, Karen E. Hedin

Blood. 2017 Aug 24; 130(8): 982–994. Prepublished online 2017 Jul 10. doi: 10.1182/blood-2017-03-770982

PMCID:: PMC5570680

Abstract Article

Select item 508699713.

A conserved αβ transmembrane interface forms the core of a compact T-cell receptor–CD3 structure within the membrane

Logesvaran Krshnan, Soohyung Park, Wonpil Im, Melissa J. Call, Matthew E. Call

Proc Natl Acad Sci U S A. 2016 Oct 25; 113(43): E6649–E6658. Published online 2016 Oct 10. doi: 10.1073/pnas.1611445113

PMCID:: PMC5086997

Abstract Article PDF–2.4M

Select item 480273614.

Recent insights into the transcriptional control of the Tcra/Tcrd locus by distant enhancers during the development of T-lymphocytes

Cristina Hernández-Munain

Transcription. 2015 Jul-Aug; 6(4): 65–73. Published online 2015 Jul 31. doi: 10.1080/21541264.2015.1078429

PMCID:: PMC4802736

Abstract Article PDF–515K

Select item 472992515.

Anaplastic large cell lymphoma arises in thymocytes and requires transient TCR expression for thymic egress

Tim I. M. Malcolm, Patrick Villarese, Camilla J. Fairbairn, Laurence Lamant, Amélie Trinquand, C. Elizabeth Hook, G. A. Amos Burke, Laurence Brugières, Katherine Hughes, Dominique Payet, Olaf Merkel, Ana-Iris Schiefer, Ibraheem Ashankyty, Shahid Mian, Mariusz Wasik, Martin Turner, Lukas Kenner, Vahid Asnafi, Elizabeth Macintyre, Suzanne D. Turner

Nat Commun. 2016; 7: 10087. Published online 2016 Jan 12. doi: 10.1038/ncomms10087

PMCID:: PMC4729925

Abstract Article PDF–1.6M

Select item 461910516.

Pre T-Cell Receptor Alpha (pTα) Expression Patterns and Functional Analysis in Human T-Cell Lymphoblastic Leukemia

Philipp Ivanyi, Michael Morgan, Wenji Piao, Sya N. Ukena, Klaus Steube, Arnold Ganser, Anke Franzke

Cell Oncol. 2010; 32(1-2): 101–108. Published online 2010 Feb 4. doi: 10.3233/CLO-2009-0500

PMCID:: PMC4619105

Abstract PDF–1.0M

Select item 457964317.

PD-1 induction through TCR activation is partially regulated by endogenous TGF-β

Raja Rekik, Nadia Belhadj Hmida, Ahlem Ben Hmid, Imen Zamali, ns Kammoun, Melika Ben Ahmed

Cell Mol Immunol. 2015 Sep; 12(5): 648–649. Published online 2014 Nov 3. doi: 10.1038/cmi.2014.104

PMCID:: PMC4579643

Article PDF–289K

Select item 451596418.

A Membrane-proximal Tetracysteine Motif Contributes to Assembly of CD3δε and CD3γε Dimers with the T Cell Receptor

Chenqi Xu, Matthew E. Call, Kai W. Wucherpfennig

J Biol Chem. Author manuscript; available in PMC 2015 Jul 27.

Published in final edited form as: J Biol Chem. 2006 Dec 1; 281(48): 36977–36984. Published online 2006 Oct 5. doi: 10.1074/jbc.M607164200

PMCID:: PMC4515964

Abstract Article PDF–1.0M

Select item 426735719.

Molecular architecture of the αβ T cell receptor–CD3 complex

Michael E. Birnbaum, Richard Berry, Yu-Shan Hsiao, Zhenjun Chen, Miguel A. Shingu-Vazquez, Xiaoling Yu, Deepa Waghray, Suzanne Fischer, James McCluskey, Jamie Rossjohn, Thomas Walz, K. Christopher Garcia

Proc Natl Acad Sci U S A. 2014 Dec 9; 111(49): 17576–17581. Published online 2014 Nov 24. doi: 10.1073/pnas.1420936111

PMCID:: PMC4267357

Abstract Article PDF–1.1M

Select item 426724220.

The molecular bases of δ/αβ T cell–mediated antigen recognition

Daniel G. Pellicci, Adam P. Uldrich, Jérôme Le Nours, Fiona Ross, Eric Chabrol, Sidonia B.G. Eckle, Renate de Boer, Ricky T. Lim, Kirsty McPherson, Gurdyal Besra, Amy R. Howell, Lorenzo Moretta, James McCluskey, Mirjam H.M. Heemskerk, Stephanie Gras, Jamie Rossjohn, Dale I. Godfrey

J Exp Med. 2014 Dec 15; 211(13): 2599–2615. doi: 10.1084/jem.20141764

PMCID:: PMC4267242

Abstract Article PDF–4.6M

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