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Items: 1 to 20 of 30

1.
Folic Acid Ameliorates Renal Injury in Experimental Obstructive Nephropathy: Role of Glycine N-Methyltransferase
Ko-Lin Kuo, Chin-Wei Chiang, Yi-Ming Arthur Chen, Chih-Chin Yu, Tzong-Shyuan Lee
Int J Mol Sci. 2023 Apr; 24(7): 6859. Published online 2023 Apr 6. doi: 10.3390/ijms24076859
PMCID:
PMC10095475
AbstractArticlePDF–5.1M
2.
Liver and brain differential expression of one-carbon metabolism genes during ontogenesis
Apolline Imbard, Leslie Schwendimann, Sophie Lebon, Pierre Gressens, Henk J. Blom, Jean-François Benoist
Sci Rep. 2021; 11: 21132. Published online 2021 Oct 26. doi: 10.1038/s41598-021-00311-9
PMCID:
PMC8548596
AbstractArticlePDF–1.3M
3.
Targeted and untargeted metabolomics provide insight into the consequences of glycine‐N‐methyltransferase deficiency including the novel finding of defective immune function
Brandon J. Eudy, Caitlin E. McDermott, Xiuli Liu, Robin P. da Silva
Physiol Rep. 2020 Sep; 8(18): e14576. Published online 2020 Sep 19. doi: 10.14814/phy2.14576
PMCID:
PMC7507444
AbstractArticlePDF–2.3M
4.
Loss of Glycine N-Methyltransferase Associates with Angiopoietin-Like Protein 8 Expression in High Fat-Diet-Fed Mice
Jian-Wei Huang, Chao-Ju Chen, Chia-Hung Yen, Yi-Ming Arthur Chen, Yu-Peng Liu
Int J Mol Sci. 2019 Sep; 20(17): 4223. Published online 2019 Aug 29. doi: 10.3390/ijms20174223
PMCID:
PMC6747252
AbstractArticlePDF–1.3M
5.
Glycine N-methyltransferase deletion in mice diverts carbon flux from gluconeogenesis to pathways that utilize excess methionine cycle intermediates
Curtis C. Hughey, Elijah Trefts, Deanna P. Bracy, Freyja D. James, E. Patrick Donahue, David H. Wasserman
J Biol Chem. 2018 Jul 27; 293(30): 11944–11954. Published online 2018 Jun 11. doi: 10.1074/jbc.RA118.002568
PMCID:
PMC6066300
AbstractArticlePDF–2.1M
6.
Glycine N-methyltransferase inhibits aristolochic acid nephropathy by increasing CYP3A44 and decreasing NQO1 expression in female mouse hepatocytes
Ming-Min Chang, Chang-Ni Lin, Cheng-Chieh Fang, Marcelo Chen, Peir-In Liang, Wei-Ming Li, Bi-Wen Yeh, Hung-Chi Cheng, Bu-Miin Huang, Wen-Jeng Wu, Yi-Ming Arthur Chen
Sci Rep. 2018; 8: 6960. Published online 2018 May 3. doi: 10.1038/s41598-018-22298-6
PMCID:
PMC5934382
AbstractArticlePDF–16M
7.
Utilizing glycine N-methyltransferasegene knockout mice as a model for identification of missing proteins in hepatocellular carcinoma
Ming-Hui Yang, Wan-Jou Chen, Yaw-Syan Fu, Bin Huang, Wan-Chi Tsai, Yi-Ming Arthur Chen, Po-Chiao Lin, Cheng-Hui Yuan, Yu-Chang Tyan
Oncotarget. 2018 Jan 2; 9(1): 442–452. Published online 2017 Dec 7. doi: 10.18632/oncotarget.23064
PMCID:
PMC5787479
AbstractArticlePDF–1.6M
8.
Glycine N-methyltransferase deficiency in female mice impairs insulin signaling and promotes gluconeogenesis by modulating the PI3K/Akt pathway in the liver
Yi-Jen Liao, Tzong-Shyuan Lee, Yuh-Ching Twu, Shih-Ming Hsu, Ching-Ping Yang, Chung-Kwe Wang, Yu-Chih Liang, Yi-Ming Arthur Chen
J Biomed Sci. 2016; 23: 69. Published online 2016 Oct 4. doi: 10.1186/s12929-016-0278-8
PMCID:
PMC5050923
AbstractArticlePDF–1.8M
9.
Role of Glycine N-Methyltransferase in the Regulation of T-Cell Responses in Experimental Autoimmune Encephalomyelitis
Chung-Hsien Li, Ming-Hong Lin, Shih-Han Chu, Pang-Hsien Tu, Cheng-Chieh Fang, Chia-Hung Yen, Peir-In Liang, Jason C Huang, Yu-Chia Su, Huey-Kang Sytwu, Yi-Ming Chen
Mol Med. 2014; 20(1): 684–696. Prepublished online 2014 Dec 12. Published online 2015 Mar 24. doi: 10.2119/molmed.2014.00133
PMCID:
PMC4398670
AbstractArticlePDF–2.7M
10.
TRAIL-producing NK cells contribute to liver injury and related fibrogenesis in the context of GNMT deficiency
Sara Fernández-Álvarez, Virginia Gutiérrez-de Juan, Imanol Zubiete-Franco, Lucia Barbier-Torres, Agustín Lahoz, Albert Parés, Zigmund Luka, Conrad Wagner, Shelly C. Lu, José M. Mato, María Luz Martínez-Chantar, Naiara Beraza
Lab Invest. Author manuscript; available in PMC 2015 Aug 1.
Published in final edited form as: Lab Invest. 2015 Feb; 95(2): 223–236. Published online 2014 Dec 22. doi: 10.1038/labinvest.2014.151
PMCID:
PMC4310762
AbstractArticlePDF–4.1M
11.
Glycine N-methyltransferase expression in the hippocampus and its role in neurogenesis and cognitive performance
Manuel Carrasco, Luis G. Rabaneda, Maribel Murillo-Carretero, Sylvia Ortega-Martínez, María L. Martínez-Chantar, Ashwin Woodhoo, Zigmund Luka, Conrad Wagner, Shelly C. Lu, José M. Mato, Juan A. Micó, Carmen Castro
Hippocampus. Author manuscript; available in PMC 2015 Jul 1.
Published in final edited form as: Hippocampus. 2014 Jul; 24(7): 840–852. Published online 2014 Apr 8. doi: 10.1002/hipo.22274
PMCID:
PMC4065208
AbstractArticlePDF–1.2M
12.
S-adenosylmethionine levels regulate the Schwann cell DNA methylome
Marta Varela-Rey, Marta Iruarrizaga-Lejarreta, Juan José Lozano, Ana María Aransay, Agustín F. Fernandez, José Luis Lavin, David Mósen-Ansorena, María Berdasco, Marc Turmaine, Zigmund Luka, Conrad Wagner, Shelly C. Lu, Manel Esteller, Rhona Mirsky, Kristján R. Jessen, Mario F. Fraga, María L. Martínez-Chantar, José M. Mato, Ashwin Woodhoo
Neuron. Author manuscript; available in PMC 2015 Mar 5.
Published in final edited form as: Neuron. 2014 Mar 5; 81(5): 1024–1039. doi: 10.1016/j.neuron.2014.01.037
PMCID:
PMC3960855
AbstractArticlePDF–6.4M
13.
Excess S-adenosylmethionine reroutes phosphatidylethanolamine towards phosphatidylcholine and triglyceride synthesis
Maite Martínez-Uña, Marta Varela-Rey, Ainara Cano, Larraitz Fernández-Ares, Naiara Beraza, Igor Aurrekoetxea, Ibon Martínez-Arranz, Juan L García-Rodríguez, Xabier Buqué, Daniela Mestre, Zigmund Luka, Conrad Wagner, Cristina Alonso, Richard H Finnell, Shelly C Lu, M Luz Martínez-Chantar, Patricia Aspichueta, José M Mato
Hepatology. Author manuscript; available in PMC 2014 Oct 1.
Published in final edited form as: Hepatology. 2013 Oct; 58(4): 1296–1305. Published online 2013 Aug 14. doi: 10.1002/hep.26399
PMCID:
PMC3720726
AbstractArticlePDF–3.2M
14.
Hepatoma Cells from Mice Deficient in Glycine N-Methyltransferase Have Increased RAS Signaling and Activation of Liver Kinase B1
Nuria Martínez-López, Juan L García-Rodríguez, Marta Varela-Rey, Virginia Gutiérrez, David Fernández-Ramos, Naiara Beraza, Ana M Aransay, Karin Schlangen, Juan Jose Lozano, Patricia Aspichueta, Zigmund Luka, Conrad Wagner, Matthias Evert, Diego F Calvisi, Shelly C Lu, José M Mato, María L Martínez-Chantar
Gastroenterology. Author manuscript; available in PMC 2013 Sep 1.
Published in final edited form as: Gastroenterology. 2012 Sep; 143(3): 787–798.e13. Published online 2012 Jun 8. doi: 10.1053/j.gastro.2012.05.050
PMCID:
PMC3429651
AbstractArticlePDF–1.9M
15.
INHIBITION OF NK CELLS PROTECTS THE LIVER AGAINST ACUTE INJURY IN THE ABSENCE OF GNMT
Laura Gomez-Santos, Zigmund Luka, Conrad Wagner, Sara Fernandez-Alvarez, Shelly C Lu, Jose M Mato, Maria L Martinez-Chantar, Naiara Beraza
Hepatology. Author manuscript; available in PMC 2013 Aug 1.
Published in final edited form as: Hepatology. 2012 Aug; 56(2): 747–759. Published online 2012 Jul 6. doi: 10.1002/hep.25694
PMCID:
PMC3378767
AbstractArticlePDF–4.5M
16.
Glycine N-Methyltransferase Deficiency Affects Niemann-Pick Type C2 Protein Stability and Regulates Hepatic Cholesterol Homeostasis
Yi-Jen Liao, Tzu-Lang Chen, Tzong-Shyuan Lee, Hsiang-An Wang, Chung-Kwe Wang, Li-Ying Liao, Ren-Shyan Liu, Shiu-Feng Huang, Yi-Ming Arthur Chen
Mol Med. 2012; 18(1): 412–422. Published online 2011 Dec 15. doi: 10.2119/molmed.2011.00258
PMCID:
PMC3356423
AbstractArticlePDF–11M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
Identification of genes concordantly expressed with Atoh1 during inner ear development
Heejei Yoon, Dong Jin Lee, Myoung Hee Kim, Jinwoong Bok
Anat Cell Biol. 2011 Mar; 44(1): 69–78. Published online 2011 Mar 31. doi: 10.5115/acb.2011.44.1.69
PMCID:
PMC3080010
AbstractArticlePDF–2.4M
19.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
20.
Impaired Liver Regeneration in Mice Lacking Glycine N-Methyltransferase
Marta Varela-Rey, David Fernández-Ramos, Nuria Martínez-López, Nieves Embade, Laura Gómez-Santos, Naiara Beraza, Mercedes Vázquez-Chantada, Juan Rodríguez, Zigmund Luka, Conrad Wagner, Shelly C Lu, M Luz Martínez-Chantar, José M Mato
Hepatology. Author manuscript; available in PMC 2010 Aug 1.
Published in final edited form as: Hepatology. 2009 Aug; 50(2): 443–452. doi: 10.1002/hep.23033
PMCID:
PMC2805126
AbstractArticlePDF–1.8M

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