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Select item 112177831.

Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner

Davy Vanhoutte, Tobias G. Schips, Rachel A. Minerath, Jiuzhou Huo, Naga Swathi Sree Kavuri, Vikram Prasad, Suh-Chin Lin, Michael J. Bround, Michelle A. Sargent, Christopher M. Adams, Jeffery D. Molkentin

Cell Rep. Author manuscript; available in PMC 2024 Jul 2.

Published in final edited form as: Cell Rep. 2024 May 28; 43(5): 114149. Published online 2024 Apr 26. doi: 10.1016/j.celrep.2024.114149

PMCID:: PMC11217783

Abstract Article PDF–3.2M

Select item 104568522.

ANT-dependent MPTP underlies necrotic myofiber death in muscular dystrophy

Michael J. Bround, Julian R. Havens, Allen J. York, Michelle A. Sargent, Jason Karch, Jeffery D. Molkentin

Sci Adv. 2023 Aug; 9(34): eadi2767. Published online 2023 Aug 25. doi: 10.1126/sciadv.adi2767

PMCID:: PMC10456852

Abstract Article PDF–1.2M

Select item 91357213.

Depletion of skeletal muscle satellite cells attenuates pathology in muscular dystrophy

Justin G. Boyer, Jiuzhou Huo, Sarah Han, Julian R. Havens, Vikram Prasad, Brian L. Lin, David A. Kass, Taejeong Song, Sakthivel Sadayappan, Ramzi J. Khairallah, Christopher W. Ward, Jeffery D. Molkentin

Nat Commun. 2022; 13: 2940. Published online 2022 May 26. doi: 10.1038/s41467-022-30619-7

PMCID:: PMC9135721

Abstract Article PDF–1.4M

Select item 79387704.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 68623225.

Lack of Delta-Sarcoglycan (Sgcd) Results in Retinal Degeneration

Andric C. Perez-Ortiz, Martha J. Peralta-Ildefonso, Esmeralda Lira-Romero, Ernesto Moya-Albor, Jorge Brieva, Israel Ramirez-Sanchez, Carmen Clapp, Alexandra Luna-Angulo, Alvaro Rendon, Elva Adan-Castro, Gabriela Ramírez-Hernández, Nundehui Díaz-Lezama, Ramón M. Coral-Vázquez, Francisco J. Estrada-Mena

Int J Mol Sci. 2019 Nov; 20(21): 5480. Published online 2019 Nov 4. doi: 10.3390/ijms20215480

PMCID:: PMC6862322

Abstract Article PDF–4.0M

Select item 67017496.

Cross-sectional study into age-related pathology of mouse models for limb girdle muscular dystrophy types 2D and 2F

Ingrid E. C. Verhaart, Kayleigh Putker, Davy van de Vijver, Christa L. Tanganyika-de Winter, Svetlana Pasteuning-Vuhman, Jaap J. Plomp, Annemieke M. Aartsma-Rus, Maaike van Putten

PLoS One. 2019; 14(8): e0220665. Published online 2019 Aug 20. doi: 10.1371/journal.pone.0220665

PMCID:: PMC6701749

Abstract Article PDF–3.2M

Select item 66938337.

Cell-specific ablation of Hsp47 defines the collagen-producing cells in the injured heart

Hadi Khalil, Onur Kanisicak, Ronald J. Vagnozzi, Anne Katrine Johansen, Bryan D. Maliken, Vikram Prasad, Justin G. Boyer, Matthew J. Brody, Tobias Schips, Katja K. Kilian, Robert N. Correll, Kunito Kawasaki, Kazuhiro Nagata, Jeffery D. Molkentin

JCI Insight. 2019 Aug 8; 4(15): e128722. Published online 2019 Aug 8. doi: 10.1172/jci.insight.128722

PMCID:: PMC6693833

Abstract Article PDF–8.4M

Select item 65426068.

ERK1/2 signaling induces skeletal muscle slow fiber-type switching and reduces muscular dystrophy disease severity

Justin G. Boyer, Vikram Prasad, Taejeong Song, Donghoon Lee, Xing Fu, Kelly M. Grimes, Michelle A. Sargent, Sakthivel Sadayappan, Jeffery D. Molkentin

JCI Insight. 2019 May 16; 4(10): e127356. Published online 2019 May 16. doi: 10.1172/jci.insight.127356

PMCID:: PMC6542606

Abstract Article PDF–4.9M

Select item 63439019.

Time-course analysis of cardiac and serum galectin-3 in viral myocarditis after an encephalomyocarditis virus inoculation

Kei Noguchi, Hiroyuki Tomita, Tomohiro Kanayama, Ayumi Niwa, Yuichiro Hatano, Masato Hoshi, Shigeyuki Sugie, Hideshi Okada, Masayuki Niwa, Akira Hara

PLoS One. 2019; 14(1): e0210971. Published online 2019 Jan 23. doi: 10.1371/journal.pone.0210971

PMCID:: PMC6343901

Abstract Article PDF–2.4M

Select item 633864110.

Genetic manipulation of CCN2/CTGF unveils cell-specific ECM-remodeling effects in injured skeletal muscle

Jennifer M. Petrosino, Andrew Leask, Federica Accornero

FASEB J. 2019 Feb; 33(2): 2047–2057. Published online 2018 Sep 14. doi: 10.1096/fj.201800622RR

PMCID:: PMC6338641

Abstract Article

Select item 555225811.

Natural disease history of mouse models for limb girdle muscular dystrophy types 2D and 2F

S. Pasteuning-Vuhman, K. Putker, C. L. Tanganyika-de Winter, J. W. Boertje-van der Meulen, L. van Vliet, M. Overzier, J. J. Plomp, A. Aartsma-Rus, M. van Putten

PLoS One. 2017; 12(8): e0182704. Published online 2017 Aug 10. doi: 10.1371/journal.pone.0182704

PMCID:: PMC5552258

Abstract Article PDF–8.4M

Select item 546168412.

Nanospan, an alternatively spliced isoform of sarcospan, localizes to the sarcoplasmic reticulum in skeletal muscle and is absent in limb girdle muscular dystrophy 2F

Angela K. Peter, Gaynor Miller, Joana Capote, Marino DiFranco, Alhondra Solares-Pérez, Emily L. Wang, Jim Heighway, Ramón M. Coral-Vázquez, Julio Vergara, Rachelle H. Crosbie-Watson

Skelet Muscle. 2017; 7: 11. Published online 2017 Jun 6. doi: 10.1186/s13395-017-0127-9

PMCID:: PMC5461684

Abstract Article PDF–6.0M

Select item 513818913.

Myocardial Contractile Dysfunction Is Present without Histopathology in a Mouse Model of Limb-Girdle Muscular Dystrophy-2F and Is Prevented after Claudin-5 Virotherapy

Nima Milani-Nejad, Eric J. Schultz, Jessica L. Slabaugh, Paul M. L. Janssen, Jill A. Rafael-Fortney

Front Physiol. 2016; 7: 539. Published online 2016 Dec 6. doi: 10.3389/fphys.2016.00539

PMCID:: PMC5138189

Abstract Article PDF–2.1M

Select item 506358814.

Thrombospondin expression in myofibers stabilizes muscle membranes

Davy Vanhoutte, Tobias G Schips, Jennifer Q Kwong, Jennifer Davis, Andoria Tjondrokoesoemo, Matthew J Brody, Michelle A Sargent, Onur Kanisicak, Hong Yi, Quan Q Gao, Joseph E Rabinowitz, Talila Volk, Elizabeth M McNally, Jeffery D Molkentin

eLife. 2016; 5: e17589. Published online 2016 Sep 26. doi: 10.7554/eLife.17589

PMCID:: PMC5063588

Abstract Article PDF–5.8M

Select item 485943715.

Altered calcium pump and secondary deficiency of γ-sarcoglycan and microspan in sarcoplasmic reticulum membranes isolated from δ-sarcoglycan knockout mice

Alhondra Solares-Pérez, Rocío Álvarez, Rachelle H. Crosbie, Jesús Vega-Moreno, Joel Medina-Monares, Francisco J. Estrada, Alicia Ortega, Ramón Coral-Vazquez

Cell Calcium. Author manuscript; available in PMC 2016 May 6.

Published in final edited form as: Cell Calcium. 2010 Jul; 48(1): 28–36. Published online 2010 Jul 16. doi: 10.1016/j.ceca.2010.06.003

PMCID:: PMC4859437

Abstract Article PDF–2.8M

Select item 485276816.

HSPB7 interacts with dimerized FLNC and its absence results in progressive myopathy in skeletal muscles

Liang-Yi Juo, Wern-Chir Liao, Yen-Ling Shih, Bih-Ying Yang, An-Bang Liu, Yu-Ting Yan

J Cell Sci. 2016 Apr 15; 129(8): 1661–1670. doi: 10.1242/jcs.179887

PMCID:: PMC4852768

Abstract Article

Select item 476419917.

Genetic overexpression of Serpina3n attenuates muscular dystrophy in mice

Andoria Tjondrokoesoemo, Tobias Schips, Onur Kanisicak, Michelle A. Sargent, Jeffery D. Molkentin

Hum Mol Genet. 2016 Mar 15; 25(6): 1192–1202. Published online 2016 Jan 6. doi: 10.1093/hmg/ddw005

PMCID:: PMC4764199

Abstract Article PDF–1.1M

Select item 438386118.

Gamma-sarcoglycan is required for the response of archvillin to mechanical stimulation in skeletal muscle

Janelle M. Spinazzola, Tara C. Smith, Min Liu, Elizabeth J. Luna, Elisabeth R. Barton

Hum Mol Genet. 2015 May 1; 24(9): 2470–2481. Published online 2015 Jan 20. doi: 10.1093/hmg/ddv008

PMCID:: PMC4383861

Abstract Article PDF–785K

Select item 431955919.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 427106220.

Myofiber-specific inhibition of TGFβ signaling protects skeletal muscle from injury and dystrophic disease in mice

Federica Accornero, Onur Kanisicak, Andoria Tjondrokoesoemo, Aria C. Attia, Elizabeth M. McNally, Jeffery D. Molkentin

Hum Mol Genet. 2014 Dec 20; 23(25): 6903–6915. Published online 2014 Aug 8. doi: 10.1093/hmg/ddu413

PMCID:: PMC4271062

Abstract Article PDF–1.4M

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