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Select item 112100801.

PANX1-mediated ATP release confers FAM3A’s suppression effects on hepatic gluconeogenesis and lipogenesis

Cheng-Qing Hu, Tao Hou, Rui Xiang, Xin Li, Jing Li, Tian-Tian Wang, Wen-Jun Liu, Song Hou, Di Wang, Qing-He Zhao, Xiao-Xing Yu, Ming Xu, Xing-Kai Liu, Yu-Jing Chi, Ji-Chun Yang

Mil Med Res. 2024; 11: 41. Published online 2024 Jun 27. doi: 10.1186/s40779-024-00543-6

PMCID:: PMC11210080

Abstract Article PDF–25M

Select item 110571802.

Neuronal Panx1 drives peripheral sensitization in experimental plantar inflammatory pain

Qu Xing, Antonio Cibelli, Greta Luyuan Yang, Preeti Dohare, Qing-Hua Li, Eliana Scemes, Fang-Xia Guan, David C. Spray

Mil Med Res. 2024; 11: 27. Published online 2024 Apr 29. doi: 10.1186/s40779-024-00525-8

PMCID:: PMC11057180

Abstract Article PDF–8.4M

Select item 110468313.

Pannexin 1 dysregulation in Duchenne muscular dystrophy and its exacerbation of dystrophic features in mdx mice

Emily Freeman, Stéphanie Langlois, Marcos F. Leyba, Tarek Ammar, Zacharie Léger, Hugh J. McMillan, Jean-Marc Renaud, Bernard J. Jasmin, Kyle N. Cowan

Skelet Muscle. 2024; 14: 8. Published online 2024 Apr 26. doi: 10.1186/s13395-024-00340-8

PMCID:: PMC11046831

Abstract Article PDF–8.0M

Select item 110462454.

NMDAR-mediated activation of pannexin1 channels contributes to the detonator properties of hippocampal mossy fiber synapses

Cinthia Rangel-Sandoval, Marisol Soula, Wei-Ping Li, Pablo E. Castillo, David L. Hunt

iScience. 2024 May 17; 27(5): 109681. Published online 2024 Apr 6. doi: 10.1016/j.isci.2024.109681

PMCID:: PMC11046245

Abstract Article PDF–5.8M

Select item 109942295.

Global pannexin 1 deletion increases tumor‐infiltrating lymphocytes in the BRAF/Pten mouse melanoma model

Rafael E. Sanchez‐Pupo, Garth A. Finch, Danielle E. Johnston, Heather Craig, Rober Abdo, Kevin Barr, Steven Kerfoot, Lina Dagnino, Silvia Penuela

Mol Oncol. 2024 Apr; 18(4): 969–987. Published online 2024 Feb 7. doi: 10.1002/1878-0261.13596

PMCID:: PMC10994229

Abstract Article PDF–2.7M

Select item 109848146.

Inhibition of pannexin‐1 does not restore electrolyte balance in precystic Pkd1 knockout mice

Wouter H. van Megen, Teun J. van Houtert, Caro Bos, Dorien J. M. Peters, Jeroen H. F. de Baaij, Joost G. J. Hoenderop

Physiol Rep. 2024 Apr; 12(7): e15956. Published online 2024 Apr 1. doi: 10.14814/phy2.15956

PMCID:: PMC10984814

Abstract Article PDF–1.9M

Select item 109176607.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108242758.

Pannexin-1 opening in neuronal edema causes initial cell death but also leads to protection via increased microglia contacts

Nicholas L. Weilinger, Kai Yang, Hyun B. Choi, Christopher J. Groten, Stefan Wendt, Madhuvika Murugan, Leigh E. Wicki-Stordeur, Louis-Philippe Bernier, Prashanth S. Velayudhan, Jiaying Zheng, Jeffrey M. LeDue, Ravi L. Rungta, John R. Tyson, Terrance P. Snutch, Long-Jun Wu, Brian A. MacVicar

Cell Rep. Author manuscript; available in PMC 2024 Jan 29.

Published in final edited form as: Cell Rep. 2023 Oct 31; 42(10): 113128. Published online 2023 Sep 23. doi: 10.1016/j.celrep.2023.113128

PMCID:: PMC10824275

Abstract Article PDF–3.1M

Select item 107237369.

Differential activation of mouse and human Panx1 channel variants

Antonio Cibelli, Preeti Dohare, David C. Spray, Eliana Scemes

PLoS One. 2023; 18(12): e0295710. Published online 2023 Dec 15. doi: 10.1371/journal.pone.0295710

PMCID:: PMC10723736

Abstract Article PDF–2.5M

Select item 1067000010.

The Inflammasome-Dependent Dysfunction and Death of Retinal Ganglion Cells after Repetitive Intraocular Pressure Spikes

Markus Spurlock, Weijun An, Galina Reshetnikova, Rong Wen, Hua Wang, Michelle Braha, Gabriela Solis, Stefan Kurtenbach, Orlando J. Galindez, Juan Pablo de Rivero Vaccari, Tsung-Han Chou, Vittorio Porciatti, Valery I. Shestopalov

Cells. 2023 Nov; 12(22): 2626. Published online 2023 Nov 15. doi: 10.3390/cells12222626

PMCID:: PMC10670000

Abstract Article PDF–6.1M

Select item 1064730111.

Contralateral Astrocyte Response to Acute Optic Nerve Damage Is Mitigated by PANX1 Channel Activity

Jasmine A. Wurl, Caitlin E. Mac Nair, Joel A. Dietz, Valery I. Shestopalov, Robert W. Nickells

Int J Mol Sci. 2023 Nov; 24(21): 15641. Published online 2023 Oct 27. doi: 10.3390/ijms242115641

PMCID:: PMC10647301

Abstract Article PDF–2.6M

Select item 1059763012.

Mitochondrial pannexin1 controls cardiac sensitivity to ischaemia/reperfusion injury

Olga M Rusiecka, Filippo Molica, Morten S Nielsen, Axel Tollance, Sandrine Morel, Maud Frieden, Marc Chanson, Kerstin Boengler, Brenda R Kwak

Cardiovasc Res. 2023 Sep; 119(13): 2342–2354. Published online 2023 Aug 9. doi: 10.1093/cvr/cvad120

PMCID:: PMC10597630

Abstract Article PDF–990K

Select item 1056362613.

Overlap in synaptic neurological condition susceptibility pathways and the neural pannexin 1 interactome revealed by bioinformatics analyses

Simona D Frederiksen, Leigh E Wicki-Stordeur, Leigh Anne Swayne

Channels (Austin) 2023; 17(1): 2253102. Published online 2023 Oct 8. doi: 10.1080/19336950.2023.2253102

PMCID:: PMC10563626

Abstract Article PDF–1.7M

Select item 1046555114.

Pannexin 1 targets mitophagy to mediate renal ischemia/reperfusion injury

Lianjiu Su, Jiahao Zhang, Jing Wang, Xiaozhan Wang, Edward Cao, Chen Yang, Qihao Sun, Ramadoss Sivakumar, Zhiyong Peng

Commun Biol. 2023; 6: 889. Published online 2023 Aug 29. doi: 10.1038/s42003-023-05226-x

PMCID:: PMC10465551

Abstract Article PDF–6.2M

Select item 1032636915.

Astrocyte and Neuronal Panx1 Support Long-Term Reference Memory in Mice

Price Obot, Galadu Subah, Antonia Schonwald, Jian Pan, Libor Velíšek, Jana Velíšková, Patric K. Stanton, Eliana Scemes

ASN Neuro. 2023 Jan-Dec; 15: 17590914231184712. Published online 2023 Jun 26. doi: 10.1177/17590914231184712

PMCID:: PMC10326369

Abstract Article PDF–1.5M

Select item 1029821316.

The Pannexin 1 Channel and the P2X7 Receptor Are in Complex Interplay to Regulate the Release of Soluble Ectonucleotidases in the Murine Bladder Lamina Propria

Mafalda S. L. Aresta Branco, Alejandro Gutierrez Cruz, Lauren E. Peri, Violeta N. Mutafova-Yambolieva

Int J Mol Sci. 2023 Jun; 24(12): 9964. Published online 2023 Jun 9. doi: 10.3390/ijms24129964

PMCID:: PMC10298213

Abstract Article PDF–4.7M

Select item 1029622217.

Pannexin-1 Modulates Inhibitory Transmission and Hippocampal Synaptic Plasticity

Francisca García-Rojas, Carolina Flores-Muñoz, Odra Santander, Pamela Solis, Agustín D. Martínez, Álvaro O. Ardiles, Marco Fuenzalida

Biomolecules. 2023 Jun; 13(6): 887. Published online 2023 May 25. doi: 10.3390/biom13060887

PMCID:: PMC10296222

Abstract Article PDF–1.6M

Select item 1026824018.

ZBTB20 is essential for cochlear maturation and hearing in mice

Zhifang Xie, Xian-Hua Ma, Qiu-Fang Bai, Jie Tang, Jian-He Sun, Fei Jiang, Wei Guo, Chen-Ma Wang, Rui Yang, Yin-Chuan Wen, Fang-Yuan Wang, Yu-Xia Chen, Hai Zhang, David Z. He, Matthew W. Kelley, Shiming Yang, Weiping J. Zhang

Proc Natl Acad Sci U S A. 2023 Jun 13; 120(24): e2220867120. Published online 2023 Jun 6. doi: 10.1073/pnas.2220867120

PMCID:: PMC10268240

Abstract Article PDF–7.7M

Select item 1001514119.

The platelet pannexin 1-IL-1β axis orchestrates pancreatic ductal adenocarcinoma invasion and metastasis

Hao Li, Wang Jiang, Shi-Rong Zhang, Peng-Cheng Li, Tian-Jiao Li, Wei Jin, Hua-Xiang Xu, Xian-Jun Yu, Liang Liu

Oncogene. 2023; 42(18): 1453–1465. Published online 2023 Mar 15. doi: 10.1038/s41388-023-02647-0

PMCID:: PMC10015141

Abstract Article PDF–6.5M

Select item 985195520.

Amount of Pannexin 1 in smooth muscle cells regulates sympathetic nerve induced vasoconstriction

Luke S. Dunaway, Marie Billaud, Edgar Macal, Miranda E. Good, Christopher B. Medina, Ulrike Lorenz, Kodi Ravichandran, Michael Koval, Brant E Isakson

Hypertension. Author manuscript; available in PMC 2024 Feb 1.

Published in final edited form as: Hypertension. 2023 Feb; 80(2): 416–425. Published online 2022 Nov 30. doi: 10.1161/HYPERTENSIONAHA.122.20280

PMCID:: PMC9851955

Abstract Article PDF–1.6M

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