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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 87788902.

Intrinsic Expression of Coagulation Factors and Protease Activated Receptor 1 (PAR1) in Photoreceptors and Inner Retinal Layers

Zehavit Goldberg, Ifat Sher, Lamis Qassim, Joab Chapman, Ygal Rotenstreich, Efrat Shavit-Stein

Int J Mol Sci. 2022 Jan; 23(2): 984. Published online 2022 Jan 17. doi: 10.3390/ijms23020984

PMCID:: PMC8778890

Abstract Article PDF–1.7M

Select item 79387703.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 68305144.

Myeloid cell-synthesized coagulation Factor X dampens anti-tumor immunity

Claudine Graf, Petra Wilgenbus, Sven Pagel, Jennifer Pott, Federico Marini, Sabine Reyda, Maki Kitano, Stephan Macher-Göppinger, Hartmut Weiler, Wolfram Ruf

Sci Immunol. Author manuscript; available in PMC 2020 Mar 20.

Published in final edited form as: Sci Immunol. 2019 Sep 20; 4(39): eaaw8405. doi: 10.1126/sciimmunol.aaw8405

PMCID:: PMC6830514

Abstract Article PDF–3.4M

Select item 67709105.

Osteopontin is An Important Regulative Component of the Fetal Bone Marrow Hematopoietic Stem Cell Niche

Huimin Cao, Benjamin Cao, Chad K. Heazlewood, Melanie Domingues, Xuan Sun, Emmanuel Debele, Narelle E. McGregor, Natalie A. Sims, Shen Y. Heazlewood, Susan K. Nilsson

Cells. 2019 Sep; 8(9): 985. Published online 2019 Aug 27. doi: 10.3390/cells8090985

PMCID:: PMC6770910

Abstract Article PDF–3.0M

Select item 64178556.

Glial cells maintain synapses by inhibiting an activity-dependent retrograde protease signal

Thomas W. Gould, Bertha Dominguez, Fred de Winter, Gene W. Yeo, Patrick Liu, Balaji Sundararaman, Thomas Stark, Anthony Vu, Jay L. Degen, Weichun Lin, Kuo-Fen Lee

PLoS Genet. 2019 Mar; 15(3): e1007948. Published online 2019 Mar 14. doi: 10.1371/journal.pgen.1007948

PMCID:: PMC6417855

Abstract Article PDF–4.1M

Select item 60341347.

Hepato‐entrained B220⁺CD11c⁺NK1.1⁺ cells regulate pre‐metastatic niche formation in the lung

Sachie Hiratsuka, Takeshi Tomita, Taishi Mishima, Yuta Matsunaga, Tsutomu Omori, Sachie Ishibashi, Satoshi Yamaguchi, Tsuyoshi Hosogane, Hiroshi Watarai, Miyuki Omori‐Miyake, Tomoko Yamamoto, Noriyuki Shibata, Akira Watanabe, Hiroyuki Aburatani, Michio Tomura, Katherine A High, Yoshiro Maru

EMBO Mol Med. 2018 Jul; 10(7): e8643. Published online 2018 Jun 21. doi: 10.15252/emmm.201708643

PMCID:: PMC6034134

Abstract Article PDF–3.4M

Select item 58211888.

VKOR paralog VKORC1L1 supports vitamin K–dependent protein carboxylation in vivo

Julie Lacombe, Mark A. Rishavy, Kathleen L. Berkner, Mathieu Ferron

JCI Insight. 2018 Jan 11; 3(1): e96501. Published online 2018 Jan 11. doi: 10.1172/jci.insight.96501

PMCID:: PMC5821188

Abstract Article PDF–2.7M

Select item 53812269.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 529582110.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 400793811.

Activated factor X signaling via protease-activated receptor 2 suppresses pro-inflammatory cytokine production from lipopolysaccharide-stimulated myeloid cells

Eimear M. Gleeson, James S. O’Donnell, Emily Hams, Fionnuala Ní Áinle, Bridget-Ann Kenny, Padraic G. Fallon, Roger J.S. Preston

Haematologica. 2014 Jan; 99(1): 185–193. doi: 10.3324/haematol.2013.086918

PMCID:: PMC4007938

Abstract Article PDF–472K

Select item 396495512.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 359184913.

A CpG Mutational Hotspot in a ONECUT Binding Site Accounts for the Prevalent Variant of Hemophilia B Leyden

Alister P.W. Funnell, Michael D. Wilson, Benoit Ballester, Ka Sin Mak, Jon Burdach, Natisha Magan, Richard C.M. Pearson, Frederic P. Lemaigre, Kathryn M. Stowell, Duncan T. Odom, Paul Flicek, Merlin Crossley

Am J Hum Genet. 2013 Mar 7; 92(3): 460–467. doi: 10.1016/j.ajhg.2013.02.003

PMCID:: PMC3591849

Abstract Article PDF–737K

Select item 345801914.

Coagulation Factor X Interaction with Macrophages through Its N-Glycans Protects It from a Rapid Clearance

Mohamad Kurdi, Ghislaine Cherel, Peter J. Lenting, Cécile V. Denis, Olivier D. Christophe

PLoS One. 2012; 7(9): e45111. Published online 2012 Sep 25. doi: 10.1371/journal.pone.0045111

PMCID:: PMC3458019

Abstract Article PDF–885K

Select item 336397715.

Factor X binding to endothelial cell protein C receptor: comparison with factor VIIa and activated protein C

Prosenjit Sen, Ramesh Nayak, Curtis A. Clark, Ramakrishnan Gopalakrishnan, Charles T. Esmon, Usha R. Pendurthi, L. Vijaya Mohan Rao

Blood. 2011 Sep 1; 118(9): 2635–2636. doi: 10.1182/blood-2011-05-354571

PMCID:: PMC3363977

Article

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 313702817.

Differential Effects of Murine and Human Factor X on Adenovirus Transduction via Cell-surface Heparan Sulfate

Anne K. Zaiss, Roger Lawrence, David Elashoff, Jeffrey D. Esko, Harvey R. Herschman

J Biol Chem. 2011 Jul 15; 286(28): 24535–24543. Published online 2011 May 19. doi: 10.1074/jbc.M111.241562

PMCID:: PMC3137028

Abstract Article PDF–986K

Select item 304626018.

Identification of Anchor Genes during Kidney Development Defines Ontological Relationships, Molecular Subcompartments and Regulatory Pathways

Rathi D. Thiagarajan, Kylie M. Georgas, Bree A. Rumballe, Emmanuelle Lesieur, Han Sheng Chiu, Darrin Taylor, Dave T. P. Tang, Sean M. Grimmond, Melissa H. Little

PLoS One. 2011; 6(2): e17286. Published online 2011 Feb 28. doi: 10.1371/journal.pone.0017286

PMCID:: PMC3046260

Abstract Article PDF–982K

Select item 288531519.

Analysis of the asymmetrically expressed Ablim1 locus reveals existence of a lateral plate Nodal-independent left sided signal and an early, left-right independent role for nodal flow

Jonathan Stevens, Alexander Ermakov, Jose Braganca, Helen Hilton, Peter Underhill, Shoumo Bhattacharya, Nigel A Brown, Dominic P Norris

BMC Dev Biol. 2010; 10: 54. Published online 2010 May 20. doi: 10.1186/1471-213X-10-54

PMCID:: PMC2885315

Abstract Article PDF–2.3M

Select item 273592220.

Increased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury

Chris J. Scotton, Malvina A. Krupiczojc, Melanie Königshoff, Paul F. Mercer, Y.C. Gary Lee, Naftali Kaminski, John Morser, Joseph M. Post, Toby M. Maher, Andrew G. Nicholson, James D. Moffatt, Geoffrey J. Laurent, Claudia K. Derian, Oliver Eickelberg, Rachel C. Chambers

J Clin Invest. 2009 Sep 1; 119(9): 2550–2563. Published online 2009 Aug 3. doi: 10.1172/JCI33288

PMCID:: PMC2735922

Abstract Article PDF–3.4M

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