PMC Links for GEO Profiles (Select 92603934) - PMC

Links from GEO Profiles

Items: 1 to 20 of 76

<< First< Prev

Page of 4

Select item 111785351.

A mitochondrial surveillance mechanism activated by SRSF2 mutations in hematologic malignancies

Xiaolei Liu, Sudhish A. Devadiga, Robert F. Stanley, Ryan M. Morrow, Kevin A. Janssen, Mathieu Quesnel-Vallières, Oz Pomp, Adam A. Moverley, Chenchen Li, Nicolas Skuli, Martin Carroll, Jian Huang, Douglas C. Wallace, Kristen W. Lynch, Omar Abdel-Wahab, Peter S. Klein

J Clin Invest. 2024 Jun 17; 134(12): e175619. Published online 2024 May 7. doi: 10.1172/JCI175619

PMCID:: PMC11178535

Abstract Article PDF–3.7M

Select item 108440882.

SRSF2 mutation cooperates with ASXL1 truncated alteration to accelerate leukemogenesis

Pinpin Sui, Guo Ge, Shi Chen, Jiaojiao Bai, Ivan P. Rubalcava, Hui Yang, Ying Guo, Peng Zhang, Ying Li, Edward A. Medina, Mingjiang Xu, Omar Abdel-Wahab, Robert Bradley, Feng-Chun Yang

Leukemia. 2024; 38(2): 408–411. Published online 2023 Nov 28. doi: 10.1038/s41375-023-02094-6

PMCID:: PMC10844088

Article PDF–2.5M

Select item 106820233.

SRSF2 mutation reduces polycythemia and impairs hematopoietic progenitor functions in JAK2V617F-driven myeloproliferative neoplasm

Yue Yang, Salar Abbas, Mohammad A. Sayem, Avik Dutta, Golam Mohi

Blood Cancer J. 2023 Dec; 13(1): 171. Published online 2023 Nov 27. doi: 10.1038/s41408-023-00947-y

PMCID:: PMC10682023

Abstract Article PDF–2.7M

Select item 105913774.

SRSF2 is required for mRNA splicing during spermatogenesis

Wen-Long Lei, Zongchang Du, Tie-Gang Meng, Ruibao Su, Yuan-Yuan Li, Wenbo Liu, Si-Min Sun, Meng-Yu Liu, Yi Hou, Chun-Hui Zhang, Yaoting Gui, Heide Schatten, Zhiming Han, Chenli Liu, Fei Sun, Zhen-Bo Wang, Wei-Ping Qian, Qing-Yuan Sun

BMC Biol. 2023; 21: 231. Published online 2023 Oct 23. doi: 10.1186/s12915-023-01736-6

PMCID:: PMC10591377

Abstract Article PDF–9.5M

Select item 102660225.

Ablation of ZC3H11A causes early embryonic lethality and dysregulation of metabolic processes

Shady Younis, Alice Jouneau, Mårten Larsson, Jean-Francois Oudin, Pierre Adenot, Jihad Omar, Vincent Brochard, Leif Andersson

Proc Natl Acad Sci U S A. 2023 Jun 6; 120(23): e2216799120. Published online 2023 May 30. doi: 10.1073/pnas.2216799120

PMCID:: PMC10266022

Abstract Article PDF–3.2M

Select item 100976686.

Inflammatory signals from fatty bone marrow support DNMT3A driven clonal hematopoiesis

N. Zioni, A. Akhiad Bercovich, N. Chapal-Ilani, Tal Bacharach, N. Rappoport, A. Solomon, R. Avraham, E. Kopitman, Z. Porat, M. Sacma, G. Hartmut, M. Scheller, C. Muller-Tidow, D. Lipka, E. Shlush, M. Minden, N. Kaushansky, Liran I. Shlush

Nat Commun. 2023; 14: 2070. Published online 2023 Apr 12. doi: 10.1038/s41467-023-36906-1

PMCID:: PMC10097668

Abstract Article PDF–7.3M

Select item 97724877.

RUNX1 deficiency cooperates with SRSF2 mutation to induce multilineage hematopoietic defects characteristic of MDS

Yi-Jou Huang, Jia-Yu Chen, Ming Yan, Amanda G. Davis, Sayuri Miyauchi, Liang Chen, Yajing Hao, Sigrid Katz, Rafael Bejar, Omar Abdel-Wahab, Xiang-Dong Fu, Dong-Er Zhang

Blood Adv. 2022 Dec 13; 6(23): 6078–6092. Published online 2022 Oct 10. doi: 10.1182/bloodadvances.2022007804

PMCID:: PMC9772487

Abstract Article PDF–2.1M

Select item 90062758.

Genome-wide screening identifies cell-cycle control as a synthetic lethal pathway with SRSF2^P95H mutation

Jane Jialu Xu, Alistair M. Chalk, Iva Nikolic, Kaylene J. Simpson, Monique F. Smeets, Carl R. Walkley

Blood Adv. 2022 Apr 12; 6(7): 2092–2106. Published online 2022 Mar 30. doi: 10.1182/bloodadvances.2021004571

PMCID:: PMC9006275

Abstract Article PDF–2.3M

Select item 87411929.

Single-cell architecture and functional requirement of alternative splicing during hematopoietic stem cell formation

Fang Wang, Puwen Tan, Pengcheng Zhang, Yue Ren, Jie Zhou, Yunqiao Li, Siyuan Hou, Shuaili Li, Linlin Zhang, Yanni Ma, Chaojie Wang, Wanbo Tang, Xiaoshuang Wang, Yue Huo, Yongfei Hu, Tianyu Cui, Chao Niu, Dong Wang, Bing Liu, Yu Lan, Jia Yu

Sci Adv. 2022 Jan; 8(1): eabg5369. Published online 2022 Jan 7. doi: 10.1126/sciadv.abg5369

PMCID:: PMC8741192

Abstract Article PDF–4.0M

Select item 817706510.

Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition

Daichi Inoue, Jacob T. Polaski, Justin Taylor, Pau Castel, Sisi Chen, Susumu Kobayashi, Simon J. Hogg, Yasutaka Hayashi, Jose Mario Bello Pineda, Ettaib El Marabti, Caroline Erickson, Katherine Knorr, Miki Fukumoto, Hiromi Yamazaki, Atsushi Tanaka, Chie Fukui, Sydney X. Lu, Benjamin H. Durham, Bo Liu, Eric Wang, Sanjoy Mehta, Daniel Zakheim, Ralph Garippa, Alex Penson, Guo-Liang Chew, Frank McCormick, Robert K. Bradley, Omar Abdel-Wahab

Nat Genet. Author manuscript; available in PMC 2021 Oct 12.

Published in final edited form as: Nat Genet. 2021 May; 53(5): 707–718. Published online 2021 Apr 12. doi: 10.1038/s41588-021-00828-9

PMCID:: PMC8177065

Abstract Article PDF–2.6M

Select item 793877011.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 724432112.

Srsf10 and the minor spliceosome control tissue-specific and dynamic SR protein expression

Stefan Meinke, Gesine Goldammer, A Ioana Weber, Victor Tarabykin, Alexander Neumann, Marco Preussner, Florian Heyd

eLife. 2020; 9: e56075. Published online 2020 Apr 27. doi: 10.7554/eLife.56075

PMCID:: PMC7244321

Abstract Article PDF–694K

Select item 720075213.

Loss of SRSF2 triggers hepatic progenitor cell activation and tumor development in mice

Chang Zhang, Lei Shen, Wei Yuan, Yuguo Liu, Ruochen Guo, Yangjun Luo, Zheng Zhan, Zhiqin Xie, Guohao Wu, Wenwu Wu, Ying Feng

Commun Biol. 2020; 3: 210. Published online 2020 May 5. doi: 10.1038/s42003-020-0893-5

PMCID:: PMC7200752

Abstract Article PDF–3.6M

Select item 685856014.

Coordinated Alterations in RNA Splicing and Epigenetic Regulation Drive Leukemogenesis

Akihide Yoshimi, Kuan-Ting Lin, Daniel H. Wiseman, Mohammad Alinoor Rahman, Alessandro Pastore, Bo Wang, Stanley Chun-Wei Lee, Jean-Baptiste Micol, Xiao Jing Zhang, Stephane de Botton, Virginie Penard-Lacronique, Eytan M. Stein, Hana Cho, Rachel E. Miles, Daichi Inoue, Todd R. Albrecht, Tim C.P. Somervaille, Kiran Batta, Fabio Amaral, Fabrizio Simeoni, Deepti P. Wilks, Catherine Cargo, Andrew M. Intlekofer, Ross L. Levine, Heidi Dvinge, Robert K. Bradley, Eric J. Wagner, Adrian R. Krainer, Omar Abdel-Wahab

Nature. Author manuscript; available in PMC 2020 Apr 2.

Published in final edited form as: Nature. 2019 Oct; 574(7777): 273–277. Published online 2019 Oct 2. doi: 10.1038/s41586-019-1618-0

PMCID:: PMC6858560

Article PDF–8.6M

Select item 660230015.

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules

Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer

J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252

PMCID:: PMC6602300

Abstract Article

Select item 637347216.

Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations

Stanley Chun-Wei Lee, Khrystyna North, Eunhee Kim, Eunjung Jang, Esther Obeng, Sydney X. Lu, Bo Liu, Daichi Inoue, Akihide Yoshimi, Michelle Ki, Mirae Yeo, Xiao Jing Zhang, Min Kyung Kim, Hana Cho, Young Rock Chung, Justin Taylor, Benjamin H. Durham, Young Joon Kim, Alessandro Pastore, Sebastien Monette, James Palacino, Michael Seiler, Silvia Buonamici, Peter G. Smith, Benjamin L. Ebert, Robert K. Bradley, Omar Abdel-Wahab

Cancer Cell. Author manuscript; available in PMC 2019 Aug 13.

Published in final edited form as: Cancer Cell. 2018 Aug 13; 34(2): 225–241.e8. doi: 10.1016/j.ccell.2018.07.003

PMCID:: PMC6373472

Abstract Article PDF–1.6M

Select item 629804017.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 624418318.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 606970519.

RNA binding proteins co-localize with small tau inclusions in tauopathy

Brandon F. Maziuk, Daniel J. Apicco, Anna Lourdes Cruz, Lulu Jiang, Peter E. A. Ash, Edroaldo Lummertz da Rocha, Cheng Zhang, Wai Haung Yu, John Leszyk, Jose F. Abisambra, Hu Li, Benjamin Wolozin

Acta Neuropathol Commun. 2018; 6: 71. Published online 2018 Aug 1. doi: 10.1186/s40478-018-0574-5

PMCID:: PMC6069705

Abstract Article PDF–5.5M

Select item 595707220.

The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations

Liang Chen, Jia-Yu Chen, Yi-Jou Huang, Ying Gu, Jinsong Qiu, Hao Qian, Changwei Shao, Xuan Zhang, Jing Hu, Hairi Li, Shunmin He, Yu Zhou, Omar Abdel-Wahab, Dong-Er Zhang, Xiang-Dong Fu

Mol Cell. Author manuscript; available in PMC 2018 May 17.

Published in final edited form as: Mol Cell. 2018 Feb 1; 69(3): 412–425.e6. Published online 2018 Jan 27. doi: 10.1016/j.molcel.2017.12.029

PMCID:: PMC5957072

Abstract Article PDF–1.2M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from GEO Profiles

Items: 1 to 20 of 76

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity