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Select item 105492261.

CDK8 and CDK19 act redundantly to control the CFTR pathway in the intestinal epithelium

Susana Prieto, Geronimo Dubra, Alain Camasses, Ana Bella Aznar, Christina Begon‐Pescia, Elisabeth Simboeck, Nelly Pirot, François Gerbe, Lucie Angevin, Philippe Jay, Liliana Krasinska, Daniel Fisher

EMBO Rep. 2023 Feb; 24(2): e54261. Published online 2022 Dec 22. doi: 10.15252/embr.202154261

PMCID:: PMC10549226

Abstract Article PDF–11M

Select item 103156222.

CDK7 controls E2F- and MYC-driven proliferative and metabolic vulnerabilities in multiple myeloma

Yao Yao, Jessica Fong Ng, Woojun Daniel Park, Mehmet Samur, Eugenio Morelli, Jessica Encinas Mayoral, Zuzana Chyra, Yan Xu, Sanika Derebail, Charles Epstein, Behnam Nabet, Marta Chesi, Nathanael S. Gray, Richard A. Young, Nicholas Kwiatkowski, Constantine Mitsiades, Kenneth C. Anderson, Charles Y. Lin, Nikhil C. Munshi, Mariateresa Fulciniti

Blood. 2023 Jun 8; 141(23): 2841–2852. Published online 2023 Mar 9. doi: 10.1182/blood.2022018885

PMCID:: PMC10315622

Abstract Article

Select item 95539513.

Neonatal ketone body elevation regulates postnatal heart development by promoting cardiomyocyte mitochondrial maturation and metabolic reprogramming

Danyang Chong, Yayun Gu, Tongyu Zhang, Yu Xu, Dandan Bu, Zhong Chen, Na Xu, Liangkui Li, Xiyu Zhu, Haiquan Wang, Yangqing Li, Feng Zheng, Dongjin Wang, Peng Li, Li Xu, Zhibin Hu, Chaojun Li

Cell Discov. 2022; 8: 106. Published online 2022 Oct 11. doi: 10.1038/s41421-022-00447-6

PMCID:: PMC9553951

Abstract Article PDF–3.8M

Select item 85641174.

Alternative Functions of Cell Cycle-Related and DNA Repair Proteins in Post-mitotic Neurons

Remi Akagawa, Yo-ichi Nabeshima, Takeshi Kawauchi

Front Cell Dev Biol. 2021; 9: 753175. Published online 2021 Oct 20. doi: 10.3389/fcell.2021.753175

PMCID:: PMC8564117

Abstract Article PDF–2.2M

Select item 73969195.

Hankyu Lee, Hyuk Wan Ko

BMB Rep. 2020 Jul 31; 53(7): 367–372. Published online 2020 Jul 31. doi: 10.5483/BMBRep.2020.53.7.295

PMCID:: PMC7396919

Abstract Article PDF–23M

Select item 72740246.

A Survey of Essential Genome Stability Genes Reveals That Replication Stress Mitigation Is Critical for Peri-Implantation Embryogenesis

Georgia R. Kafer, Anthony J. Cesare

Front Cell Dev Biol. 2020; 8: 416. Published online 2020 May 29. doi: 10.3389/fcell.2020.00416

PMCID:: PMC7274024

Abstract Article PDF–1.3M

Select item 72566317.

CDK7 Mediates the Beta-Adrenergic Signaling in Thermogenic Brown and White Adipose Tissues

Honglei Ji, Yizhe Chen, Judit Castillo-Armengol, René Dreos, Catherine Moret, Guy Niederhäuser, Brigitte Delacuisine, Isabel C. Lopez-Mejia, Pierre-Damien Denechaud, Lluis Fajas

iScience. 2020 Jun 26; 23(6): 101163. Published online 2020 May 15. doi: 10.1016/j.isci.2020.101163

PMCID:: PMC7256631

Abstract Article PDF–6.6M

Select item 62150098.

Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis

Seungtae Moon, Sun-Kyoung Im, Nackhyoung Kim, Hyesook Youn, Ui-Hyun Park, Joo-Yeon Kim, A.-Reum Kim, So-Jung An, Ji-Hoon Kim, Woong Sun, Jin-Taek Hwang, Eun-Joo Kim, Soo-Jong Um

Cell Death Dis. 2018 Nov; 9(11): 1118. Published online 2018 Nov 2. doi: 10.1038/s41419-018-1171-z

PMCID:: PMC6215009

Abstract Article PDF–2.7M

Select item 56819599.

Cdk7 Is Required for Activity-Dependent Neuronal Gene Expression, Long-Lasting Synaptic Plasticity and Long-Term Memory

Guiqin He, Xiangyu Yang, Guo Wang, Junxia Qi, Rui Mao, Zhengping Wu, Zikai Zhou

Front Mol Neurosci. 2017; 10: 365. Published online 2017 Nov 7. doi: 10.3389/fnmol.2017.00365

PMCID:: PMC5681959

Abstract Article PDF–2.6M

Select item 494476110.

CDK7 and miR-210 Co-regulate Cell-Cycle Progression of Neural Progenitors in the Developing Neocortex

Aisha I. Abdullah, Haijun Zhang, Yanzhen Nie, Wei Tang, Tao Sun

Stem Cell Reports. 2016 Jul 12; 7(1): 69–79. Published online 2016 Jul 12. doi: 10.1016/j.stemcr.2016.06.005

PMCID:: PMC4944761

Abstract Article PDF–5.3M

Select item 492482611.

Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome

Ronghui Li, Qiping Dong, Xinni Yuan, Xin Zeng, Yu Gao, Cassandra Chiao, Hongda Li, Xinyu Zhao, Sunduz Keles, Zefeng Wang, Qiang Chang

PLoS Genet. 2016 Jun; 12(6): e1006129. Published online 2016 Jun 28. doi: 10.1371/journal.pgen.1006129

PMCID:: PMC4924826

Abstract Article PDF–1.9M

Select item 424491012.

Targeting transcription regulation in cancer with a covalent CDK7 inhibitor

Nicholas Kwiatkowski, Tinghu Zhang, Peter B Rahl, Brian J Abraham, Jessica Reddy, Scott B Ficarro, Anahita Dastur, Arnaud Amzallag, Sridhar Ramaswamy, Bethany Tesar, Christopher R Jenkins, Nancy M Hannett, Douglas McMillin, Takaomi Sanda, Taebo Sim, Nam Doo Kim, Thomas Look, Constantine Mitsiades, Andrew P Weng, Jennifer R Brown, Cyril H. Benes, Jarrod A Marto, Richard A Young, Nathanael S. Gray

Nature. Author manuscript; available in PMC 2015 Jan 31.

Published in final edited form as: Nature. 2014 Jul 31; 511(7511): 616–620. Published online 2014 Jun 22. doi: 10.1038/nature13393

PMCID:: PMC4244910

Abstract Article PDF–4.3M

Select item 357241013.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 336543114.

Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion

Miguel Ganuza, Cristina Sáiz-Ladera, Marta Cañamero, Gonzalo Gómez, Ralph Schneider, María A Blasco, David Pisano, Jesús M Paramio, David Santamaría, Mariano Barbacid

EMBO J. 2012 May 30; 31(11): 2498–2510. Published online 2012 Apr 13. doi: 10.1038/emboj.2012.94

PMCID:: PMC3365431

Abstract Article PDF–2.1M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 286530816.

Functional Analysis of the Cdk7·Cyclin H·Mat1 Complex in Mouse Embryonic Stem Cells and Embryos

Shetal A. Patel, M. Celeste Simon

J Biol Chem. 2010 May 14; 285(20): 15587–15598. Published online 2010 Mar 15. doi: 10.1074/jbc.M109.081687

PMCID:: PMC2865308

Abstract Article PDF–4.1M

Select item 263069817.

SUMOylation Inhibits SF-1 Activity by Reducing CDK7-Mediated Serine 203 Phosphorylation

Wei-Hsiung Yang, Joanne H. Heaton, Holly Brevig, Sarmistha Mukherjee, Jorge A. Iñiguez-Lluhí, Gary D. Hammer

Mol Cell Biol. 2009 Feb; 29(3): 613–625. Published online 2008 Nov 17. doi: 10.1128/MCB.00295-08

PMCID:: PMC2630698

Abstract Article PDF–1.0M

Select item 261250018.

Mat1 Inhibits Peroxisome Proliferator-Activated Receptor γ-Mediated Adipocyte Differentiation

Katja Helenius, Ying Yang, Jukka Alasaari, Tomi P. Mäkelä

Mol Cell Biol. 2009 Jan; 29(2): 315–323. Published online 2008 Nov 3. doi: 10.1128/MCB.00347-08

PMCID:: PMC2612500

Abstract Article PDF–1.2M

Select item 255627019.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Abstract Article PDF–493K

Select item 216939220.

AIRE Recruits P-TEFb for Transcriptional Elongation of Target Genes in Medullary Thymic Epithelial Cells

Irena Oven, Naděžda Brdičková, Jiri Kohoutek, Tomaž Vaupotič, Mojca Narat, B. Matija Peterlin

Mol Cell Biol. 2007 Dec; 27(24): 8815–8823. Published online 2007 Oct 15. doi: 10.1128/MCB.01085-07

PMCID:: PMC2169392

Abstract Article PDF–409K

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