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Select item 111499351.

SAFB regulates hippocampal stem cell fate by targeting Drosha to destabilize Nfib mRNA

Pascal Forcella, Niklas Ifflander, Chiara Rolando, Elli-Anna Balta, Aikaterini Lampada, Claudio Giachino, Tanzila Mukhtar, Thomas Bock, Verdon Taylor

eLife. 2024; 13: e74940. Published online 2024 May 9. doi: 10.7554/eLife.74940

PMCID:: PMC11149935

Abstract Article PDF–19M

Select item 93485762.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 92709723.

Uncoupling transcription and translation through miRNA-dependent poly(A) length control in haploid male germ cells

Mei Guo, Chunhai Luo, Zhuqing Wang, Sheng Chen, Dayton Morris, Fengying Ruan, Zhichao Chen, Linfeng Yang, Xiongyi Wei, Chuanwen Wu, Bei Luo, Zhou Lv, Jin Huang, Dong Zhang, Cong Yu, Qiang Gao, Hongqi Wang, Ying Zhang, Fei Sun, Wei Yan, Chong Tang

Development. 2022 Jun 15; 149(12): dev199573. Published online 2022 Jun 16. doi: 10.1242/dev.199573

PMCID:: PMC9270972

Abstract Article

Select item 83132394.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 82974445.

Global miRNA dosage control of embryonic germ layer specification

Yingzi Cui, Xuehui Lv, Li Ding, Lan Ke, Dechang Yang, Mehdi Pirouz, Ye Qi, Jennie Ong, Ge Gao, Peng Du, Richard I. Gregory

Nature. Author manuscript; available in PMC 2021 Nov 5.

Published in final edited form as: Nature. 2021 May; 593(7860): 602–606. Published online 2021 May 5. doi: 10.1038/s41586-021-03524-0

PMCID:: PMC8297444

Abstract Article PDF–5.2M

Select item 80121036.

Control of ribosomal protein synthesis by the Microprocessor complex

Xuan Jiang, Amit Prabhakar, Stephanie M. Van der Voorn, Prajakta Ghatpande, Barbara Celona, Srivats Venkataramanan, Lorenzo Calviello, Chuwen Lin, Wanpeng Wang, Brian L. Black, Stephen N. Floor, Giorgio Lagna, Akiko Hata

Sci Signal. Author manuscript; available in PMC 2021 Aug 23.

Published in final edited form as: Sci Signal. 2021 Feb 23; 14(671): eabd2639. Published online 2021 Feb 23. doi: 10.1126/scisignal.abd2639

PMCID:: PMC8012103

Abstract Article PDF–3.1M

Select item 79387707.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 68536378.

The mammalian LINC complex component SUN1 regulates muscle regeneration by modulating drosha activity

Tsui Han Loo, Xiaoqian Ye, Ruth Jinfen Chai, Mitsuteru Ito, Gisèle Bonne, Anne C Ferguson-Smith, Colin L Stewart

eLife. 2019; 8: e49485. Published online 2019 Nov 5. doi: 10.7554/eLife.49485

PMCID:: PMC6853637

Abstract Article PDF–7.3M

Select item 65856379.

The miRNA biogenesis pathway prevents inappropriate expression of injury response genes in developing and adult Schwann cells

Deniz Gökbuget, Jorge A. Pereira, Lennart Opitz, Dominik Christe, Tobias Kessler, Antonin Marchais, Ueli Suter

Glia. 2018 Dec; 66(12): 2632–2644. Published online 2018 Oct 8. doi: 10.1002/glia.23516

PMCID:: PMC6585637

Abstract Article PDF–7.5M

Select item 606388810.

Milk exosomes are bioavailable and distinct microRNA cargos have unique tissue distribution patterns

Sonia Manca, Bijaya Upadhyaya, Ezra Mutai, Amy T. Desaulniers, Rebecca A. Cederberg, Brett R. White, Janos Zempleni

Sci Rep. 2018; 8: 11321. Published online 2018 Jul 27. doi: 10.1038/s41598-018-29780-1

PMCID:: PMC6063888

Abstract Article PDF–6.7M

Select item 599219611.

Loss of Drosha underlies dopaminergic neuron toxicity in models of Parkinson’s disease

Ronglin Wang, Fangfang Lu, Gang Zhu, Dayun Feng, Tiejian Nie, Kai Tao, Shaosong Yang, Jie Lei, Lu Huang, Zixu Mao, Qian Yang

Cell Death Dis. 2018 Jun; 9(6): 693. Published online 2018 Jun 7. doi: 10.1038/s41419-018-0716-5

PMCID:: PMC5992196

Abstract Article PDF–2.6M

Select item 596257512.

Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy

Inês do Carmo G. Gonçalves, Johanna Brecht, Maximilian P. Thelen, Wiebke A. Rehorst, Miriam Peters, Hyun Ju Lee, Susanne Motameny, Laura Torres-Benito, Darius Ebrahimi-Fakhari, Natalia L. Kononenko, Janine Altmüller, David Vilchez, Mustafa Sahin, Brunhilde Wirth, Min Jeong Kye

Sci Rep. 2018; 8: 7907. Published online 2018 May 21. doi: 10.1038/s41598-018-26347-y

Correction in:: Sci Rep. 2018; 8: 10294.

Correction in:: Sci Rep. 2020; 10: 8206.

PMCID:: PMC5962575

Abstract Article PDF–6.0M

Select item 581126113.

Inactivating mutations in Drosha mediate vascular abnormalities similar to hereditary hemorrhagic telangiectasia

Xuan Jiang, Whitney L. Wooderchak-Donahue, Jamie McDonald, Prajakta Ghatpande, Mai Baalbaki, Melissa Sandoval, Daniel Hart, Hilary Clay, Shaun Coughlin, Giorgio Lagna, Pinar Bayrak-Toydemir, Akiko Hata

Sci Signal. Author manuscript; available in PMC 2018 Feb 13.

Published in final edited form as: Sci Signal. 2018 Jan 16; 11(513): eaan6831. Published online 2018 Jan 16. doi: 10.1126/scisignal.aan6831

PMCID:: PMC5811261

Abstract Article PDF–1.7M

Select item 576615714.

A novel requirement for DROSHA in maintenance of mammalian CG methylation

Athanasia Stathopoulou, Jyoti B. Chhetri, John C. Ambrose, Pierre-Olivier Estève, Lexiang Ji, Hediye Erdjument-Bromage, Guoqiang Zhang, Thomas A. Neubert, Sriharsa Pradhan, Javier Herrero, Robert J. Schmitz, Steen K.T. Ooi

Nucleic Acids Res. 2017 Sep 19; 45(16): 9398–9412. Published online 2017 Aug 3. doi: 10.1093/nar/gkx695

Correction in:: Nucleic Acids Res. 2017 Sep 19; 45(16): 9810.

PMCID:: PMC5766157

Abstract Article PDF–4.1M

Select item 567908015.

miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation

Maryaline Coffre, David Benhamou, David Rieß, Lili Blumenberg, Valentina Snetkova, Marcus J. Hines, Tirtha Chakraborty, Sofia Bajwa, Kari Jensen, Mark M.W. Chong, Lelise Getu, Gregg J. Silverman, Robert Blelloch, Dan R. Littman, Dinis Calado, Doron Melamed, Jane A. Skok, Klaus Rajewsky, Sergei B. Koralov

Cell Rep. Author manuscript; available in PMC 2017 Nov 9.

Published in final edited form as: Cell Rep. 2016 Nov 22; 17(9): 2271–2285. doi: 10.1016/j.celrep.2016.11.006

PMCID:: PMC5679080

Abstract Article PDF–1.2M

Select item 556106016.

Genome-wide identification and expression profiling of long non-coding RNAs in auditory and vestibular systems

Kathy Ushakov, Tal Koffler-Brill, Aviv Rom, Kobi Perl, Igor Ulitsky, Karen B. Avraham

Sci Rep. 2017; 7: 8637. Published online 2017 Aug 17. doi: 10.1038/s41598-017-08320-3

PMCID:: PMC5561060

Abstract Article PDF–4.9M

Select item 552700717.

Let-7 microRNA-dependent control of leukotriene signaling regulates the transition of hematopoietic niche in mice

Xuan Jiang, John S. Hawkins, Jerry Lee, Carlos O. Lizama, Frank L. Bos, Joan P. Zape, Prajakta Ghatpande, Yongbo Peng, Justin Louie, Giorgio Lagna, Ann C. Zovein, Akiko Hata

Nat Commun. 2017; 8: 128. Published online 2017 Jul 25. doi: 10.1038/s41467-017-00137-y

PMCID:: PMC5527007

Abstract Article PDF–3.8M

Select item 547313818.

DROSHA targets its own transcript to modulate alternative splicing

Dooyoung Lee, Jin-Wu Nam, Chanseok Shin

RNA. 2017 Jul; 23(7): 1035–1047. doi: 10.1261/rna.059808.116

PMCID:: PMC5473138

Abstract Article PDF–526K

Select item 482541219.

Dicer1-mediated miRNA processing shapes the mRNA profile and function of murine platelets

Jesse W. Rowley, Stéphane Chappaz, Aurélie Corduan, Mark M. W. Chong, Robert Campbell, Amanda Khoury, Bhanu Kanth Manne, Jeremy G. T. Wurtzel, James V. Michael, Lawrence E. Goldfinger, Michele M. Mumaw, Marvin T. Nieman, Benjamin T. Kile, Patrick Provost, Andrew S. Weyrich

Blood. 2016 Apr 7; 127(14): 1743–1751. Prepublished online 2016 Jan 14. doi: 10.1182/blood-2015-07-661371

PMCID:: PMC4825412

Abstract Article

Select item 476032220.

Sperm-borne miRNAs and endo-siRNAs are important for fertilization and preimplantation embryonic development

Shuiqiao Yuan, Andrew Schuster, Chong Tang, Tian Yu, Nicole Ortogero, Jianqiang Bao, Huili Zheng, Wei Yan

Development. 2016 Feb 15; 143(4): 635–647. doi: 10.1242/dev.131755

PMCID:: PMC4760322

Abstract Article

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