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Items: 1 to 20 of 346

1.
Preservation of vision by transpalpebral electrical stimulation in mice with inherited retinal degeneration
Kasim Gunes, Karen Chang, Anton Lennikov, Wai Lydia Tai, Julie Chen, Farris ElZaridi, Kin-Sang Cho, Tor Paaske Utheim, Chen Dong Feng
Front Cell Dev Biol. 2024; 12: 1412909. Published online 2024 Aug 14. doi: 10.3389/fcell.2024.1412909
PMCID:
PMC11349514
AbstractArticlePDF–2.3M
2.
A combination treatment based on drug repurposing demonstrates mutation-agnostic efficacy in pre-clinical retinopathy models
Henri Leinonen, Jianye Zhang, Laurence M. Occelli, Umair Seemab, Elliot H. Choi, Luis Felipe L.P. Marinho, Janice Querubin, Alexander V. Kolesnikov, Anna Galinska, Katarzyna Kordecka, Thanh Hoang, Dominik Lewandowski, Timothy T. Lee, Elliott E. Einstein, David E. Einstein, Zhiqian Dong, Philip D. Kiser, Seth Blackshaw, Vladimir J. Kefalov, Marcin Tabaka, Andrzej Foik, Simon M. Petersen-Jones, Krzysztof Palczewski
Nat Commun. 2024; 15: 5943. Published online 2024 Jul 15. doi: 10.1038/s41467-024-50033-5
PMCID:
PMC11251169
AbstractArticlePDF–17M
3.
Automated quantification of photoreceptor outer segments in developing and degenerating retinas on microscopy images across scales
Suse Seidemann, Florian Salomon, Karl B. Hoffmann, Thomas Kurth, Ivo F. Sbalzarini, Robert Haase, Marius Ader
Front Mol Neurosci. 2024; 17: 1398447. Published online 2024 May 24. doi: 10.3389/fnmol.2024.1398447
PMCID:
PMC11157083
AbstractArticlePDF–21M
4.
CRISPR editing of anti-anemia drug target rescues independent preclinical models of retinitis pigmentosa
Nicholas D. Nolan, Xuan Cui, Brian M. Robbings, Aykut Demirkol, Kriti Pandey, Wen-Hsuan Wu, Hannah F. Hu, Laura A. Jenny, Chyuan-Sheng Lin, Daniel T. Hass, Jianhai Du, James B. Hurley, Stephen H. Tsang
Cell Rep Med. 2024 Apr 16; 5(4): 101459. Published online 2024 Mar 21. doi: 10.1016/j.xcrm.2024.101459
PMCID:
PMC11031380
AbstractArticlePDF–6.3M
5.
Voluntary exercise preserves visual function and reduces inflammatory response in an adult mouse model of autosomal dominant retinitis pigmentosa
Katie L. Bales, Austin M. Karesh, Kelleigh Hogan, Alicia S. Chacko, GianMarco L. Douglas, Andrew J. Feola, John M. Nickerson, Alyssa Pybus, Levi Wood, Jeffrey H. Boatright, Machelle T. Pardue
Sci Rep. 2024; 14: 6940. Published online 2024 Mar 23. doi: 10.1038/s41598-024-57027-9
PMCID:
PMC10960803
AbstractArticlePDF–4.2M
6.
Aggregation of rhodopsin mutants in mouse models of autosomal dominant retinitis pigmentosa
Sreelakshmi Vasudevan, Subhadip Senapati, Maryanne Pendergast, Paul S.–H. Park
Nat Commun. 2024; 15: 1451. Published online 2024 Feb 16. doi: 10.1038/s41467-024-45748-4
PMCID:
PMC10873427
AbstractArticlePDF–12M
7.
Super-resolution mapping in rod photoreceptors identifies rhodopsin trafficking through the inner segment plasma membrane as an essential subcellular pathway
Kristen N. Haggerty, Shannon C. Eshelman, Lauren A. Sexton, Emmanuel Frimpong, Leah M. Rogers, Melina A. Agosto, Michael A. Robichaux
PLoS Biol. 2024 Jan; 22(1): e3002467. Published online 2024 Jan 8. doi: 10.1371/journal.pbio.3002467
PMCID:
PMC10773939
AbstractArticlePDF–8.1M
8.
Maf1 controls retinal neuron number by both RNA Pol III- and Pol II-dependent mechanisms
Yifei Li, Dongchang Xiao, Haiqiao Chen, X.F. Steven Zheng, Mengqing Xiang
iScience. 2023 Dec 15; 26(12): 108544. Published online 2023 Nov 23. doi: 10.1016/j.isci.2023.108544
PMCID:
PMC10711482
AbstractArticlePDF–9.9M
9.
mRNA trans-splicing dual AAV vectors for (epi)genome editing and gene therapy
Lisa Maria Riedmayr, Klara Sonnie Hinrichsmeyer, Stefan Bernhard Thalhammer, David Manuel Mittas, Nina Karguth, Dina Yehia Otify, Sybille Böhm, Valentin Johannes Weber, Michael David Bartoschek, Victoria Splith, Manuela Brümmer, Raphael Ferreira, Nanda Boon, Gabriele Maria Wögenstein, Christian Grimm, Jan Wijnholds, Verena Mehlfeld, Stylianos Michalakis, Stefanie Fenske, Martin Biel, Elvir Becirovic
Nat Commun. 2023; 14: 6578. Published online 2023 Oct 18. doi: 10.1038/s41467-023-42386-0
PMCID:
PMC10584818
AbstractArticlePDF–2.9M
10.
Mettl14-mediated m6A modification ensures the cell-cycle progression of late-born retinal progenitor cells
Liang Li, Yue Sun, Alexander E. Davis, Sahil H. Shah, Lobna K. Hamed, Man-Ru Wu, Cheng-Hui Lin, Jun B. Ding, Sui Wang
Cell Rep. Author manuscript; available in PMC 2023 Oct 2.
Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112596. Published online 2023 Jun 1. doi: 10.1016/j.celrep.2023.112596
PMCID:
PMC10543643
AbstractArticlePDF–3.9M
11.
Highly sensitive visual restoration and protection via ectopic expression of chimeric rhodopsin in mice
Yusaku Katada, Kazuho Yoshida, Naho Serizawa, Deokho Lee, Kenta Kobayashi, Kazuno Negishi, Hideyuki Okano, Hideki Kandori, Kazuo Tsubota, Toshihide Kurihara
iScience. 2023 Oct 20; 26(10): 107716. Published online 2023 Aug 25. doi: 10.1016/j.isci.2023.107716
PMCID:
PMC10504486
AbstractArticlePDF–5.1M
12.
Rho enhancers play unexpectedly minor roles in Rhodopsin transcription and rod cell integrity
Chi Sun, Philip A. Ruzycki, Shiming Chen
Sci Rep. 2023; 13: 12899. Published online 2023 Aug 9. doi: 10.1038/s41598-023-39979-6
PMCID:
PMC10412641
AbstractArticlePDF–3.3M
13.
Chromatin remodeler Chd7 regulates photoreceptor development and outer segment length
Laura A. Krueger, Jessica D. Bills, Zun Yi Lim, Jennifer M. Skidmore, Donna M. Martin, Ann C. Morris
Exp Eye Res. Author manuscript; available in PMC 2023 Jul 19.
Published in final edited form as: Exp Eye Res. 2023 Jan; 226: 109299. Published online 2022 Nov 4. doi: 10.1016/j.exer.2022.109299
PMCID:
PMC10354686
AbstractArticlePDF–1.3M
14.
Overexpression of Nfe2l1 increases proteasome activity and delays vision loss in a preclinical model of human blindness
Yixiao Wang, Aaron Snell, Frank M. Dyka, Elizabeth R. Colvin, Cristhian Ildefonso, John D. Ash, Ekaterina S. Lobanova
Sci Adv. 2023 Jul; 9(28): eadd5479. Published online 2023 Jul 14. doi: 10.1126/sciadv.add5479
PMCID:
PMC10348684
AbstractArticlePDF–2.1M
15.
Structural abnormalities of retinal pigment epithelial cells in a light‐inducible, rhodopsin mutant mouse
Debora Napoli, Enrica Strettoi
J Anat. 2023 Aug; 243(2): 223–234. Published online 2022 Apr 15. doi: 10.1111/joa.13667
PMCID:
PMC10335375
AbstractArticlePDF–8.6M
16.
Chromophore supply modulates cone function and survival in retinitis pigmentosa mouse models
Yunlu Xue, Xiaomei Sun, Sean K. Wang, Gayle B. Collin, Vladimir J. Kefalov, Constance L. Cepko
Proc Natl Acad Sci U S A. 2023 Jun 6; 120(23): e2217885120. Published online 2023 May 30. doi: 10.1073/pnas.2217885120
PMCID:
PMC10266038
AbstractArticlePDF–5.5M
17.
Jarid2 promotes temporal progression of retinal progenitors via repression of Foxp1
Jianmin Zhang, Jacqueline M. Roberts, Fei Chang, Joon Schwakopf, Monica L. Vetter
Cell Rep. Author manuscript; available in PMC 2023 May 25.
Published in final edited form as: Cell Rep. 2023 Mar 28; 42(3): 112237. Published online 2023 Mar 14. doi: 10.1016/j.celrep.2023.112237
Correction in:
Cell Rep. 2023 Apr 25; 42(4): 112416.
PMCID:
PMC10210259
AbstractArticlePDF–4.4M
18.
Chromatin Remodeling Enzyme Snf2h Is Essential for Retinal Cell Proliferation and Photoreceptor Maintenance
Andrea Kuzelova, Naoko Dupacova, Barbora Antosova, Sweetu Susan Sunny, Zbynek Kozmik, Jr., Jan Paces, Arthur I. Skoultchi, Tomas Stopka, Zbynek Kozmik
Cells. 2023 Apr; 12(7): 1035. Published online 2023 Mar 28. doi: 10.3390/cells12071035
PMCID:
PMC10093269
AbstractArticlePDF–21M
19.
Biphasic expression of thyroid hormone receptor TRβ1 in mammalian retina and anterior ocular tissues
Lily Ng, Hong Liu, Ye Liu, Douglas Forrest
Front Endocrinol (Lausanne) 2023; 14: 1174600. Published online 2023 Mar 23. doi: 10.3389/fendo.2023.1174600
PMCID:
PMC10076699
AbstractArticlePDF–17M
20.
Investigating the Role of Rhodopsin F45L Mutation in Mouse Rod Photoreceptor Signaling and Survival
Deepak Poria, Alexander V. Kolesnikov, Tae Jun Lee, David Salom, Krzysztof Palczewski, Vladimir J. Kefalov
eNeuro. 2023 Mar; 10(3): ENEURO.0330-22.2023. Prepublished online 2023 Feb 21. Published online 2023 Mar 2. doi: 10.1523/ENEURO.0330-22.2023
PMCID:
PMC9997694
AbstractArticlePDF–2.4M

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