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Select item 87288721.

The Tyrosine Kinase Tec Regulates Effector Th17 Differentiation, Pathogenicity, and Plasticity in T-Cell-Driven Intestinal Inflammation

Lisa Sandner, Marlis Alteneder, Ci Zhu, Anastasiya Hladik, Sandra Högler, Ramona Rica, Lars W. Van Greuningen, Omar Sharif, Shinya Sakaguchi, Sylvia Knapp, Lukas Kenner, Michael Trauner, Wilfried Ellmeier, Nicole Boucheron

Front Immunol. 2021; 12: 750466. Published online 2021 Dec 21. doi: 10.3389/fimmu.2021.750466

PMCID:: PMC8728872

Abstract Article PDF–7.3M

Select item 79387702.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 63334603.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Abstract Article PDF–2.7M

Select item 54709544.

Inhibitor of Tec kinase, LFM-A13, decreases pro-inflammatory mediators production in LPS-stimulated RAW264.7 macrophages via NF-κB pathway

Fei Wang, Wei Zhang, Chao Wang, Xu Fang, Hao Cheng, Sheng Liu, Xu-Lin Chen

Oncotarget. 2017 May 23; 8(21): 34099–34110. Published online 2017 Mar 15. doi: 10.18632/oncotarget.16212

PMCID:: PMC5470954

Abstract Article PDF–6.0M

Select item 53082185.

The Proximal Signaling Network of the BCR-ABL1 Oncogene Shows a Modular Organization

Björn Titz, Tracey Low, Evangelia Komisopoulou, Sharon S Chen, Liudmilla Rubbi, Thomas G Graeber

Oncogene. Author manuscript; available in PMC 2017 Feb 14.

Published in final edited form as: Oncogene. 2010 Nov 4; 29(44): 5895–5910. Published online 2010 Aug 9. doi: 10.1038/onc.2010.331

PMCID:: PMC5308218

Abstract Article PDF–3.8M

Select item 44754456.

The Tec kinase-regulated phosphoproteome reveals a mechanism for the regulation of inhibitory signals in murine macrophages

Giacomo Tampella, Hannah M. Kerns, Deqiang Niu, Swati Singh, Socheath Khim, Katherine A. Bosch, Meghan E. Garrett, Albanus Moguche, Erica Evans, Beth Browning, Tahmina A. Jahan, Mariana Nacht, Alejandro Wolf-Yadlin, Alessandro Plebani, Jessica A. Hamerman, David J. Rawlings, Richard G. James

J Immunol. Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: J Immunol. 2015 Jul 1; 195(1): 246–256. Published online 2015 May 29. doi: 10.4049/jimmunol.1403238

PMCID:: PMC4475445

Abstract Article PDF–1.5M

Select item 44391287.

Reciprocal Regulation of C-Maf Tyrosine Phosphorylation by Tec and Ptpn22

Chih-Chun Liu, Chen-Yen Lai, Wei-Feng Yen, Yu-Hsien Lin, Hui-Hsin Chang, Tzong-Shyuan Tai, Yu-Jung Lu, Hsiao-Wei Tsao, I-Cheng Ho, Shi-Chuen Miaw

PLoS One. 2015; 10(5): e0127617. Published online 2015 May 20. doi: 10.1371/journal.pone.0127617

PMCID:: PMC4439128

Abstract Article PDF–2.1M

Select item 44168598.

Distinct Pathways Regulate Syk Protein Activation Downstream of Immune Tyrosine Activation Motif (ITAM) and hemITAM Receptors in Platelets

Bhanu Kanth Manne, Rachit Badolia, Carol Dangelmaier, Johannes A. Eble, Wilfried Ellmeier, Mark Kahn, Satya P. Kunapuli

J Biol Chem. 2015 May 1; 290(18): 11557–11568. Published online 2015 Mar 12. doi: 10.1074/jbc.M114.629527

PMCID:: PMC4416859

Abstract Article PDF–1.9M

Select item 42566819.

The Non-receptor Tyrosine Kinase Tec Controls Assembly and Activity of the Noncanonical Caspase-8 Inflammasome

Florian Zwolanek, Michael Riedelberger, Valentina Stolz, Sabrina Jenull, Fabian Istel, Afitap Derya Köprülü, Wilfried Ellmeier, Karl Kuchler

PLoS Pathog. 2014 Dec; 10(12): e1004525. Published online 2014 Dec 4. doi: 10.1371/journal.ppat.1004525

PMCID:: PMC4256681

Abstract Article PDF–1.8M

Select item 407640510.

Peri-Implantation Hormonal Milieu: Elucidating Mechanisms of Abnormal Placentation and Fetal Growth

Monica A. Mainigi, Devvora Olalere, Irina Burd, Carmen Sapienza, Marisa Bartolomei, Christos Coutifaris

Biol Reprod. 2014 Feb; 90(2): 26. Published online 2013 Dec 18. doi: 10.1095/biolreprod.113.110411

PMCID:: PMC4076405

Abstract Article PDF–1015K

Select item 363145211.

Trypanosoma cruzi trans-sialidase initiates an ROR-?t–AHR-independent program leading to IL-17 production by activated B cells

Daniela A Bermejo, Shaun W Jackson, Melisa Gorosito-Serran, Eva V Acosta-Rodriguez, Maria C Amezcua-Vesely, Blythe D Sather, Akhilesh K. Singh, Socheath Khim, Juan Mucci, Denny Liggitt, Oscar Campetella, Mohamed Oukka, Adriana Gruppi, David J Rawlings

Nat Immunol. Author manuscript; available in PMC 2013 Nov 1.

Published in final edited form as: Nat Immunol. 2013 May; 14(5): 514–522. Published online 2013 Apr 7. doi: 10.1038/ni.2569

PMCID:: PMC3631452

Abstract Article PDF–2.8M

Select item 361643412.

Early estrogen-induced gene 1, a novel RANK signaling component, is essential for osteoclastogenesis

Han Kyoung Choi, Hye Ri Kang, Eutteum Jung, Tae Eon Kim, Jing Jing Lin, Soo Young Lee

Cell Res. 2013 Apr; 23(4): 524–536. Published online 2013 Mar 12. doi: 10.1038/cr.2013.33

PMCID:: PMC3616434

Abstract Article PDF–6.0M

Select item 357241013.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 300119315.

Essential roles for the Tec family kinases Tec and Btk in M-CSF receptor signaling pathways that regulate macrophage survival

Martin Melcher, Bernd Unger, Uwe Schmidt, Iiro A Rajantie, Kari Alitalo, Wilfried Ellmeier

J Immunol. Author manuscript; available in PMC 2010 Dec 13.

Published in final edited form as: J Immunol. 2008 Jun 15; 180(12): 8048–8056. doi: 10.4049/jimmunol.180.12.8048

PMCID:: PMC3001193

Abstract Article PDF–1.7M

Select item 294449516.

Stress signaling by Tec tyrosine kinase in the ischemic myocardium

Michael J. Zhang, Sarah Franklin, Yifeng Li, Sujing Wang, Xiaochen Ru, Scherise A. Mitchell-Jordan, Hiroyuki Mano, Enrico Stefani, Peipei Ping, Thomas M. Vondriska

Am J Physiol Heart Circ Physiol. 2010 Sep; 299(3): H713–H722. Published online 2010 Jun 11. doi: 10.1152/ajpheart.00273.2010

PMCID:: PMC2944495

Abstract Article

Select item 293586117.

Locus category based analysis of a large genome-wide association study of rheumatoid arthritis

Jan Freudenberg, Annette T. Lee, Katherine A. Siminovitch, Christopher I. Amos, David Ballard, Wentian Li, Peter K. Gregersen

Hum Mol Genet. 2010 Oct 1; 19(19): 3863–3872. Published online 2010 Jul 16. doi: 10.1093/hmg/ddq304

PMCID:: PMC2935861

Abstract Article PDF–201K

Select item 289321018.

Modeling Susceptibility versus Resistance in Allergic Airway Disease Reveals Regulation by Tec Kinase Itk

Nisebita Sahu, J. Luis Morales, Deborah Fowell, Avery August

PLoS One. 2010; 5(6): e11348. Published online 2010 Jun 28. doi: 10.1371/journal.pone.0011348

PMCID:: PMC2893210

Abstract Article PDF–2.5M

Select item 219310619.

Severe B Cell Deficiency in Mice Lacking the Tec Kinase Family Members Tec and Btk

Wilfried Ellmeier, Steffen Jung, Mary Jean Sunshine, Farah Hatam, Yang Xu, David Baltimore, Hiroyuki Mano, Dan R. Littman

J Exp Med. 2000 Dec 4; 192(11): 1611–1624. doi: 10.1084/jem.192.11.1611

PMCID:: PMC2193106

Abstract Article PDF–475K

Select item 208090720.

Myc stimulates B lymphocyte differentiation and amplifies calcium signaling

Tania Habib, Heon Park, Mark Tsang, Ignacio Moreno de Alborán, Andrea Nicks, Leslie Wilson, Paul S. Knoepfler, Sarah Andrews, David J. Rawlings, Robert N. Eisenman, Brian M. Iritani

J Cell Biol. 2007 Nov 19; 179(4): 717–731. doi: 10.1083/jcb.200704173

PMCID:: PMC2080907

Abstract Article PDF–5.4M

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