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Select item 111832621.

Spatially distinct epithelial and mesenchymal cell subsets along progressive lineage restriction in the branching embryonic mammary gland

Claudia Carabaña, Wenjie Sun, Camila Veludo Ramos, Mathilde Huyghe, Meghan Perkins, Aurélien Maillot, Robin Journot, Fatima Hartani, Marisa M Faraldo, Bethan Lloyd-Lewis, Silvia Fre

EMBO J. 2024 Jun; 43(12): 2308–2336. Published online 2024 May 17. doi: 10.1038/s44318-024-00115-3

PMCID:: PMC11183262

Abstract Article PDF–11M

Select item 110961762.

Proteostatic reactivation of the developmental transcription factor TBX3 drives BRAF/MAPK-mediated tumorigenesis

Zhenlei Zhang, Yufan Wu, Jinrong Fu, Xiujie Yu, Yang Su, Shikai Jia, Huili Cheng, Yan Shen, Xianghui He, Kai Ren, Xiangqian Zheng, Haixia Guan, Feng Rao, Li Zhao

Nat Commun. 2024; 15: 4108. Published online 2024 May 15. doi: 10.1038/s41467-024-48173-9

Correction in:: Nat Commun. 2024; 15: 4936.

PMCID:: PMC11096176

Abstract Article PDF–5.7M

Select item 110149533.

Protein restriction during pregnancy alters Cdkn1c silencing, dopamine circuitry and offspring behaviour without changing expression of key neuronal marker genes

Chiara Prodani, Elaine E. Irvine, Alessandro Sardini, Hannah J. Gleneadie, Andrew Dimond, Mathew Van de Pette, Rosalind John, Michelle Kokkinou, Oliver Howes, Dominic J. Withers, Mark A. Ungless, Matthias Merkenschlager, Amanda G. Fisher

Sci Rep. 2024; 14: 8528. Published online 2024 Apr 12. doi: 10.1038/s41598-024-59083-7

PMCID:: PMC11014953

Abstract Article PDF–1.7M

Select item 109896904.

Epigenetic control of the imprinted growth regulator Cdkn1c in cadmium-induced placental dysfunction

Mark D. Simmers, Kathleen M. Hudson, Marine Baptissart, Michael Cowley

Epigenetics. 2023; 18(1): 2088173. Published online 2022 Jun 30. doi: 10.1080/15592294.2022.2088173

PMCID:: PMC10989690

Abstract Article PDF–5.0M

Select item 109176605.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107232236.

JAM-C Is Important for Lens Epithelial Cell Proliferation and Lens Fiber Maturation in Murine Lens Development

Qihang Sun, Jiani Li, Jingyu Ma, Yuxing Zheng, Rong Ju, Xuri Li, Xiangrong Ren, Lijuan Huang, Rongyuan Chen, Xuhua Tan, Lixia Luo

Invest Ophthalmol Vis Sci. 2023 Dec; 64(15): 15. Published online 2023 Dec 14. doi: 10.1167/iovs.64.15.15

PMCID:: PMC10723223

Abstract Article PDF–36M

Select item 105070537.

KLF4 regulates skeletal muscle development and regeneration by directly targeting P57 and Myomixer

Shufang Cai, Xiaoyu Wang, Rong Xu, Ziyun Liang, Qi Zhu, Meilin Chen, Zhuhu Lin, Chenggan Li, Tianqi Duo, Xian Tong, Enru Li, Zuyong He, Xiaohong Liu, Yaosheng Chen, Delin Mo

Cell Death Dis. 2023 Sep; 14(9): 612. Published online 2023 Sep 18. doi: 10.1038/s41419-023-06136-w

PMCID:: PMC10507053

Abstract Article PDF–11M

Select item 103131768.

Atoh1 drives the heterogeneity of the pontine nuclei neurons and promotes their differentiation

Sih-Rong Wu, Jessica C. Butts, Matthew S. Caudill, Jean-Pierre Revelli, Ryan S. Dhindsa, Mark A. Durham, Huda Y. Zoghbi

Sci Adv. 2023 Jun; 9(26): eadg1671. Published online 2023 Jun 30. doi: 10.1126/sciadv.adg1671

PMCID:: PMC10313176

Abstract Article PDF–1.9M

Select item 102855499.

Uterine-specific Ezh2 deletion enhances stromal cell senescence and impairs placentation, resulting in pregnancy loss

Vijay K. Sirohi, Theresa I. Medrano, Athilakshmi Kannan, Indrani C. Bagchi, Paul S. Cooke

iScience. 2023 Jul 21; 26(7): 107028. Published online 2023 Jun 8. doi: 10.1016/j.isci.2023.107028

PMCID:: PMC10285549

Abstract Article PDF–5.7M

Select item 993114710.

p57^Kip2 is an essential regulator of vitamin D receptor-dependent mechanisms

Katsuhiko Takahashi, Hitoshi Amano, Tomohiko Urano, Minqi Li, Meiko Oki, Kazuhiro Aoki, Norio Amizuka, Keiichi I. Nakayama, Keiko Nakayama, Nobuyuki Udagawa, Nobuaki Higashi

PLoS One. 2023; 18(2): e0276838. Published online 2023 Feb 15. doi: 10.1371/journal.pone.0276838

PMCID:: PMC9931147

Abstract Article PDF–1.4M

Select item 990320511.

IGF2 interacts with the imprinted gene Cdkn1c to promote terminal differentiation of neural stem cells

Anna Lozano-Ureña, Laura Lázaro-Carot, Esteban Jiménez-Villalba, Raquel Montalbán-Loro, Isabel Mateos-White, Pere Duart-Abadía, Irene Martínez-Gurrea, Keiichi I. Nakayama, Isabel Fariñas, Martina Kirstein, Cristina Gil-Sanz, Sacri R. Ferrón

Development. 2023 Jan 1; 150(1): dev200563. Published online 2023 Jan 12. doi: 10.1242/dev.200563

PMCID:: PMC9903205

Abstract Article

Select item 987008912.

ZEB2 controls kidney stromal progenitor differentiation and inhibits abnormal myofibroblast expansion and kidney fibrosis

Sudhir Kumar, Xueping Fan, Hila Milo Rasouly, Richa Sharma, David J. Salant, Weining Lu

JCI Insight. 2023 Jan 10; 8(1): e158418. Published online 2023 Jan 10. doi: 10.1172/jci.insight.158418

PMCID:: PMC9870089

Abstract Article PDF–8.1M

Select item 985174613.

Heterozygous variants in SIX3 and POU1F1 cause pituitary hormone deficiency in mouse and man

Hironori Bando, Michelle L Brinkmeier, Frederic Castinetti, Qing Fang, Mi-Sun Lee, Alexandru Saveanu, Frédérique Albarel, Clémentine Dupuis, Thierry Brue, Sally A Camper

Hum Mol Genet. 2023 Feb 1; 32(3): 367–385. Published online 2022 Aug 11. doi: 10.1093/hmg/ddac192

PMCID:: PMC9851746

Abstract Article PDF–3.5M

Select item 945909514.

Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects

Shaili D. Patel, Deepti Anand, Hozumi Motohashi, Fumiki Katsuoka, Masayuki Yamamoto, Salil A. Lachke

Front Cell Dev Biol. 2022; 10: 981893. Published online 2022 Aug 26. doi: 10.3389/fcell.2022.981893

PMCID:: PMC9459095

Abstract Article PDF–5.1M

Select item 939141715.

Endothelial-specific Gata3 expression is required for hematopoietic stem cell generation

Nada Zaidan, Leslie Nitsche, Evangelia Diamanti, Rebecca Hannah, Antonella Fidanza, Nicola K. Wilson, Lesley M. Forrester, Berthold Göttgens, Katrin Ottersbach

Stem Cell Reports. 2022 Aug 9; 17(8): 1788–1798. Published online 2022 Jul 28. doi: 10.1016/j.stemcr.2022.06.008

PMCID:: PMC9391417

Abstract Article PDF–2.9M

Select item 935315116.

p57Kip2 regulates embryonic blood stem cells by controlling sympathoadrenal progenitor expansion

Chrysa Kapeni, Leslie Nitsche, Alastair M. Kilpatrick, Nicola K. Wilson, Kankan Xia, Bahar Mirshekar-Syahkal, Vashe Chandrakanthan, Camille Malouf, John E. Pimanda, Berthold Göttgens, Kristina Kirschner, Simon R. Tomlinson, Katrin Ottersbach

Blood. 2022 Aug 4; 140(5): 464–477. doi: 10.1182/blood.2021014853

PMCID:: PMC9353151

Abstract Article

Select item 909777617.

p57^Kip2 imposes the reserve stem cell state of gastric chief cells

Ji-Hyun Lee, Somi Kim, Seungmin Han, Jimin Min, Brianna Caldwell, Aileen-Diane Bamford, Andreia Sofia Batista Rocha, JinYoung Park, Sieun Lee, Szu-Hsien Sam Wu, Heetak Lee, Juergen Fink, Sandra Pilat-Carotta, Jihoon Kim, Manon Josserand, Réka Szep-Bakonyi, Yohan An, Young Seok Ju, Anna Philpott, Benjamin D. Simons, Daniel E. Stange, Eunyoung Choi, Bon-Kyoung Koo, Jong Kyoung Kim

Cell Stem Cell. 2022 May 5; 29(5): 826–839.e9. doi: 10.1016/j.stem.2022.04.001

PMCID:: PMC9097776

Abstract Article

Select item 905556218.

Znhit1 Regulates p21^Cip1 to Control Mouse Lens Differentiation

Juan Lu, Jianhong An, Jiawei Wang, Xiaowen Cao, Yuqing Cao, Chengjie Huang, Shiming Jiao, Dongsheng Yan, Xinhua Lin, Xiangtian Zhou

Invest Ophthalmol Vis Sci. 2022 Apr; 63(4): 18. Published online 2022 Apr 26. doi: 10.1167/iovs.63.4.18

PMCID:: PMC9055562

Abstract Article PDF–46M

Select item 893850719.

Spatiotemporal reprogramming of differentiated cells underlies regeneration and neoplasia in the intestinal epithelium

Tsunaki Higa, Yasutaka Okita, Akinobu Matsumoto, Shogo Nakayama, Takeru Oka, Osamu Sugahara, Daisuke Koga, Shoichiro Takeishi, Hirokazu Nakatsumi, Naoki Hosen, Sylvie Robine, Makoto M. Taketo, Toshiro Sato, Keiichi I. Nakayama

Nat Commun. 2022; 13: 1500. Published online 2022 Mar 21. doi: 10.1038/s41467-022-29165-z

PMCID:: PMC8938507

Abstract Article PDF–11M

Select item 878304120.

Smad4 controls proliferation of interstitial cells in the neonatal kidney

Sarah S. McCarthy, Michele Karolak, Leif Oxburgh

Development. 2022 Jan 1; 149(1): dev199984. Published online 2022 Jan 4. doi: 10.1242/dev.199984

PMCID:: PMC8783041

Abstract Article

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