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Items: 1 to 20 of 135

1.
Astrocytic metabolic control of orexinergic activity in the lateral hypothalamus regulates sleep and wake architecture
Alice Braga, Martina Chiacchiaretta, Luc Pellerin, Dong Kong, Philip G. Haydon
Nat Commun. 2024; 15: 5979. Published online 2024 Jul 16. doi: 10.1038/s41467-024-50166-7
PMCID:
PMC11252394
AbstractArticlePDF–15M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Hypothalamic orexinergic neurons modulate pain and itch in an opposite way: pain relief and itch exacerbation
Tatsuroh Kaneko, Tomoyuki Kuwaki, Hideki Kashiwadani
J Physiol Sci. 2022; 72: 21. Published online 2022 Aug 22. doi: 10.1186/s12576-022-00846-0
PMCID:
PMC10717118
AbstractArticlePDF–1.6M
4.
Dopamine release in the nucleus accumbens promotes REM sleep and cataplexy
Brandon A. Toth, Katie S. Chang, Sarah Fechtali, Christian R. Burgess
iScience. 2023 Sep 15; 26(9): 107613. Published online 2023 Aug 11. doi: 10.1016/j.isci.2023.107613
PMCID:
PMC10470413
AbstractArticlePDF–12M
5.
Structure and Function of Neuronal Circuits Linking Ventrolateral Preoptic Nucleus and Lateral Hypothalamic Area
Kseniia Prokofeva, Yuki C. Saito, Yasutaka Niwa, Seiya Mizuno, Satoru Takahashi, Arisa Hirano, Takeshi Sakurai
J Neurosci. 2023 May 31; 43(22): 4075–4092. doi: 10.1523/JNEUROSCI.1913-22.2023
PMCID:
PMC10255079
AbstractArticlePDF–8.3M
6.
Anterior cingulate cortex orexin signaling mediates early-life stress-induced social impairment in females
Fei Luo, Jun-yang Deng, Xuan Sun, Jian Zhen, Xiao-dan Luo
Proc Natl Acad Sci U S A. 2023 May 16; 120(20): e2220353120. Published online 2023 May 8. doi: 10.1073/pnas.2220353120
PMCID:
PMC10193930
AbstractArticlePDF–10M
7.
Casein kinase 1α is required to maintain murine hypothalamic pro-opiomelanocortin expression
Chenyang Lu, Jinglin Zhang, Bingjie Wang, Qiao Gao, Kezhe Ma, Shaona Pei, Juxue Li, Sheng Cui
iScience. 2023 May 19; 26(5): 106670. Published online 2023 Apr 14. doi: 10.1016/j.isci.2023.106670
PMCID:
PMC10165255
AbstractArticlePDF–8.2M
8.
Orexin induces the production of an endocannabinoid-derived lysophosphatidic acid eliciting hypothalamic synaptic loss in obesity
Alba Clara Fernández-Rilo, Nicola Forte, Letizia Palomba, Lea Tunisi, Fabiana Piscitelli, Roberta Imperatore, Alfonso Di Costanzo, Vincenzo Di Marzo, Luigia Cristino
Mol Metab. 2023 Jun; 72: 101713. Published online 2023 Mar 26. doi: 10.1016/j.molmet.2023.101713
PMCID:
PMC10122056
AbstractArticlePDF–4.1M
9.
The development of sleep/wake disruption and cataplexy as hypocretin/orexin neurons degenerate in male vs. female Orexin/tTA; TetO-DTA Mice
Yu Sun, Ryan Tisdale, Sunmee Park, Shun-Chieh Ma, Jasmine Heu, Meghan Haire, Giancarlo Allocca, Akihiro Yamanaka, Stephen R Morairty, Thomas S Kilduff
Sleep. 2022 Dec; 45(12): zsac039. Published online 2022 Feb 19. doi: 10.1093/sleep/zsac039
PMCID:
PMC9742901
AbstractArticlePDF–2.4M
10.
Hypocretin/orexin influences chronic sleep disruption injury in the hippocampus
Henry Nick, Polina Fenik, Yan Zhu, Sigrid Veasey
Front Aging Neurosci. 2022; 14: 1025402. Published online 2022 Oct 6. doi: 10.3389/fnagi.2022.1025402
PMCID:
PMC9582517
AbstractArticlePDF–5.3M
11.
Mutual Effects of Orexin and Bone Morphogenetic Proteins on Gonadotropin Expression by Mouse Gonadotrope Cells
Yoshiaki Soejima, Nahoko Iwata, Nanako Nakayama, Shinichi Hirata, Yasuhiro Nakano, Koichiro Yamamoto, Atsuhito Suyama, Kohei Oguni, Takahiro Nada, Satoshi Fujisawa, Fumio Otsuka
Int J Mol Sci. 2022 Sep; 23(17): 9782. Published online 2022 Aug 29. doi: 10.3390/ijms23179782
PMCID:
PMC9456022
AbstractArticlePDF–3.9M
12.
Hyperexcitable arousal circuits drive sleep instability during aging
Shi-Bin Li, Valentina Martinez Damonte, Chong Chen, Gordon X. Wang, Justus M. Kebschull, Hiroshi Yamaguchi, Wen-Jie Bian, Carolin Purmann, Reenal Pattni, Alexander Eckehart Urban, Philippe Mourrain, Julie A. Kauer, Grégory Scherrer, Luis de Lecea
Science. Author manuscript; available in PMC 2022 May 14.
Published in final edited form as: Science. 2022 Feb 25; 375(6583): eabh3021. Published online 2022 Feb 25. doi: 10.1126/science.abh3021
PMCID:
PMC9107327
AbstractArticlePDF–3.0M
13.
Selective requirement for polycomb repressor complex 2 in the generation of specific hypothalamic neuronal subtypes
Behzad Yaghmaeian Salmani, Brad Balderson, Susanne Bauer, Helen Ekman, Annika Starkenberg, Thomas Perlmann, Michael Piper, Mikael Bodén, Stefan Thor
Development. 2022 Mar 1; 149(5): dev200076. Published online 2022 Mar 7. doi: 10.1242/dev.200076
PMCID:
PMC8959139
AbstractArticle
14.
Orexin A peptidergic system: comparative sleep behavior, morphology and population in brains between wild type and Alzheimer’s disease mice
Peng Zhao, Yaqian You, Zhe Wang, Yanjun Zhou, Gaoshang Chai, Gen Yan, Zhewu Jin, Qing Wang, Hongxu Sun
Brain Struct Funct. 2022; 227(3): 1051–1065. Published online 2022 Jan 23. doi: 10.1007/s00429-021-02447-w
PMCID:
PMC8930968
AbstractArticlePDF–10M
15.
Activity of putative orexin neurons during cataplexy
Shi Zhou, Akira Yamashita, Jingyang Su, Yang Zhang, Wuyang Wang, Liying Hao, Akihiro Yamanaka, Tomoyuki Kuwaki
Mol Brain. 2022; 15: 21. Published online 2022 Mar 4. doi: 10.1186/s13041-022-00907-w
PMCID:
PMC8896372
AbstractArticlePDF–3.9M
16.
Narcolepsy: A Key Role for Hypocretins (Orexins)
Jerome M. Siegel
Cell. Author manuscript; available in PMC 2022 Feb 13.
Published in final edited form as: Cell. 1999 Aug 20; 98(4): 409–412. doi: 10.1016/s0092-8674(00)81969-8
PMCID:
PMC8841059
ArticlePDF–391K
17.
Gender differences between hypocretin/orexin knockout and wild type mice: age, body weight, body composition, metabolic markers, leptin and insulin resistance
Lalini Ramanathan, Jerome M. Siegel
J Neurochem. Author manuscript; available in PMC 2022 Jan 6.
Published in final edited form as: J Neurochem. 2014 Dec; 131(5): 615–624. Published online 2014 Aug 21. doi: 10.1111/jnc.12840
PMCID:
PMC8734533
AbstractArticlePDF–1024K
18.
Brain circuit of claustrophobia-like behavior in mice identified by upstream tracing of sighing
Peng Li, Shi-Bin Li, Xuenan Wang, Chrystian D. Phillips, Lindsay A. Schwarz, Liqun Luo, Luis de Lecea, Mark A. Krasnow
Cell Rep. Author manuscript; available in PMC 2021 Nov 9.
Published in final edited form as: Cell Rep. 2020 Jun 16; 31(11): 107779. doi: 10.1016/j.celrep.2020.107779
PMCID:
PMC8576489
AbstractArticlePDF–2.1M
19.
Hypothalamic kinin B1 receptor mediates orexin system hyperactivity in neurogenic hypertension
Rohan Umesh Parekh, Acacia White, Korin E. Leffler, Vinicia C. Biancardi, Jeffrey B. Eells, Abdel A. Abdel-Rahman, Srinivas Sriramula
Sci Rep. 2021; 11: 21050. Published online 2021 Oct 26. doi: 10.1038/s41598-021-00522-0
PMCID:
PMC8548389
AbstractArticlePDF–3.6M
20.
Orexin-A and endocannabinoids are involved in obesity-associated alteration of hippocampal neurogenesis, plasticity, and episodic memory in mice
Nicola Forte, Serena Boccella, Lea Tunisi, Alba Clara Fernández-Rilo, Roberta Imperatore, Fabio Arturo Iannotti, Maria De Risi, Monica Iannotta, Fabiana Piscitelli, Raffaele Capasso, Paolo De Girolamo, Elvira De Leonibus, Sabatino Maione, Vincenzo Di Marzo, Luigia Cristino
Nat Commun. 2021; 12: 6137. Published online 2021 Oct 21. doi: 10.1038/s41467-021-26388-4
PMCID:
PMC8531398
AbstractArticlePDF–8.3M

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