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Select item 114382691.

Knockdown of microglial iron import gene, Slc11a2, worsens cognitive function and alters microglial transcriptional landscape in a sex-specific manner in the APP/PS1 model of Alzheimer’s disease

Katrina Volk Robertson, Alec S. Rodriguez, Jean-Philippe Cartailler, Shristi Shrestha, Michael W. Schleh, Kyle R. Schroeder, Arianna M. Valenti, Alec T. Kramer, Fiona E. Harrison, Alyssa H. Hasty

J Neuroinflammation. 2024; 21: 238. Published online 2024 Sep 27. doi: 10.1186/s12974-024-03238-w

PMCID:: PMC11438269

Abstract Article PDF–2.9M

Select item 112748612.

Ischemic Neuroprotection by Insulin with Down-Regulation of Divalent Metal Transporter 1 (DMT1) Expression and Ferrous Iron-Dependent Cell Death

Francesca Fenaroli, Alessandra Valerio, Rosaria Ingrassia

Biomolecules. 2024 Jul; 14(7): 856. Published online 2024 Jul 15. doi: 10.3390/biom14070856

PMCID:: PMC11274861

Abstract Article PDF–588K

Select item 110246843.

DMT1 ubiquitination by Nedd4 protects against ferroptosis after intracerebral hemorrhage

Bingchen Lv, Ping Fu, Miao Wang, Likun Cui, Lei Bao, Xingzhi Wang, Lu Yu, Chao Zhou, Mengxin Zhu, Fei Wang, Ye Pang, Suhua Qi, Zuohui Zhang, Guiyun Cui

CNS Neurosci Ther. 2024 Apr; 30(4): e14685. Published online 2024 Apr 18. doi: 10.1111/cns.14685

PMCID:: PMC11024684

Abstract Article PDF–20M

Select item 105846564.

H-ferritin expression in astrocytes is necessary for proper oligodendrocyte development and myelination

VT Cheli, DA Santiago González, Q Wan, G Denaroso, R Wan, SL Rosenblum, PM Paez

Glia. Author manuscript; available in PMC 2023 Oct 19.

Published in final edited form as: Glia. 2021 Dec; 69(12): 2981–2998. Published online 2021 Aug 30. doi: 10.1002/glia.24083

PMCID:: PMC10584656

Abstract Article PDF–9.1M

Select item 92235315.

DMT1 Protects Macrophages from Salmonella Infection by Controlling Cellular Iron Turnover and Lipocalin 2 Expression

Manuel Grander, Alexander Hoffmann, Markus Seifert, Egon Demetz, Philipp Grubwieser, Christa Pfeifhofer-Obermair, David Haschka, Günter Weiss

Int J Mol Sci. 2022 Jun; 23(12): 6789. Published online 2022 Jun 17. doi: 10.3390/ijms23126789

PMCID:: PMC9223531

Abstract Article PDF–2.8M

Select item 88571856.

Iron from nanostructured ferric phosphate: absorption and biodistribution in mice and bioavailability in iron deficient anemic women

Jeannine Baumgartner, Hans Christian Winkler, Lizelle Zandberg, Siriporn Tuntipopipat, Phatchari Mankong, Cor Bester, Florentine Hilty, Jan Rijn Zeevaart, Sueppong Gowachirapant, Michael B. Zimmermann

Sci Rep. 2022; 12: 2792. Published online 2022 Feb 18. doi: 10.1038/s41598-022-06701-x

PMCID:: PMC8857185

Abstract Article PDF–2.4M

Select item 83483737.

Divalent Metal Transporter 1 Knock-Down Modulates IL-1β Mediated Pancreatic Beta-Cell Pro-Apoptotic Signaling Pathways through the Autophagic Machinery

Taewook Kang, Honggang Huang, Thomas Mandrup-Poulsen, Martin R. Larsen

Int J Mol Sci. 2021 Aug; 22(15): 8013. Published online 2021 Jul 27. doi: 10.3390/ijms22158013

PMCID:: PMC8348373

Abstract Article PDF–5.7M

Select item 81570408.

Oral Administration of Ginger-Derived Lipid Nanoparticles and Dmt1 siRNA Potentiates the Effect of Dietary Iron Restriction and Mitigates Pre-Existing Iron Overload in Hamp KO Mice

Xiaoyu Wang, Mingzhen Zhang, Regina R. Woloshun, Yang Yu, Jennifer K. Lee, Shireen R. L. Flores, Didier Merlin, James F. Collins

Nutrients. 2021 May; 13(5): 1686. Published online 2021 May 15. doi: 10.3390/nu13051686

PMCID:: PMC8157040

Abstract Article PDF–2.3M

Select item 75156879.

Fetal liver hepcidin secures iron stores in utero

Lara Kämmerer, Goran Mohammad, Magda Wolna, Peter A. Robbins, Samira Lakhal-Littleton

Blood. 2020 Sep 24; 136(13): 1549–1557. Prepublished online 2020 Jun 15. doi: 10.1182/blood.2019003907

PMCID:: PMC7515687

Abstract Article

Select item 697895310.

Iron Metabolism in the Peripheral Nervous System: The Role of DMT1, Ferritin, and Transferrin Receptor in Schwann Cell Maturation and Myelination

Diara A. Santiago González, Veronica T. Cheli, Rensheng Wan, Pablo M. Paez

J Neurosci. 2019 Dec 11; 39(50): 9940–9953. doi: 10.1523/JNEUROSCI.1409-19.2019

PMCID:: PMC6978953

Abstract Article PDF–9.0M

Select item 640457911.

Hyperglycemia promotes microvillus membrane expression of DMT1 in intestinal epithelial cells in a PKCα-dependent manner

Luqing Zhao, Thomas Bartnikas, Xiangpeng Chu, Janet Klein, Chris Yun, Shanthi Srinivasan, Peijian He

FASEB J. 2019 Mar; 33(3): 3549–3561. Published online 2018 Nov 13. doi: 10.1096/fj.201801855R

PMCID:: PMC6404579

Abstract Article

Select item 630794412.

Hepatic hepcidin/intestinal HIF-2α axis maintains iron absorption during iron deficiency and overload

Andrew J. Schwartz, Nupur K. Das, Sadeesh K. Ramakrishnan, Chesta Jain, Mladen T. Jurkovic, Jun Wu, Elizabeta Nemeth, Samira Lakhal-Littleton, Justin A. Colacino, Yatrik M. Shah

J Clin Invest. 2019 Jan 2; 129(1): 336–348. Published online 2018 Dec 10. doi: 10.1172/JCI122359

PMCID:: PMC6307944

Abstract Article PDF–11M

Select item 619940713.

The Divalent Metal Transporter 1 (DMT1) Is Required for Iron Uptake and Normal Development of Oligodendrocyte Progenitor Cells

Veronica T. Cheli, Diara A. Santiago González, Leandro N. Marziali, Norma N. Zamora, María E. Guitart, Vilma Spreuer, Juana M. Pasquini, Pablo M. Paez

J Neurosci. 2018 Oct 24; 38(43): 9142–9159. doi: 10.1523/JNEUROSCI.1447-18.2018

PMCID:: PMC6199407

Abstract Article PDF–13M

Select item 599176814.

Nuclear m⁶A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development

Seth D. Kasowitz, Jun Ma, Stephen J. Anderson, N. Adrian Leu, Yang Xu, Brian D. Gregory, Richard M. Schultz, P. Jeremy Wang

PLoS Genet. 2018 May; 14(5): e1007412. Published online 2018 May 25. doi: 10.1371/journal.pgen.1007412

PMCID:: PMC5991768

Abstract Article PDF–19M

Select item 549543715.

Interleukin-6 regulates iron-related proteins through c-Jun N-terminal kinase activation in BV2 microglial cell lines

Shida Zhou, Xinxing Du, Junxia Xie, Jun Wang

PLoS One. 2017; 12(7): e0180464. Published online 2017 Jul 3. doi: 10.1371/journal.pone.0180464

PMCID:: PMC5495437

Abstract Article PDF–3.8M

Select item 502348616.

Iron Uptake via DMT1 Integrates Cell Cycle with JAK-STAT3 Signaling to Promote Colorectal Tumorigenesis

Xiang Xue, Sadeesh K. Ramakrishnan, Kevin Weisz, Daniel Triner, Liwei Xie, Durga Attili, Asha Pant, Balázs Győrffy, Mingkun Zhan, Christin Carter-Su, Karin M. Hardiman, Thomas D. Wang, Michael K. Dame, James Varani, Dean Brenner, Eric R. Fearon, Yatrik M. Shah

Cell Metab. Author manuscript; available in PMC 2017 Sep 13.

Published in final edited form as: Cell Metab. 2016 Sep 13; 24(3): 447–461. Published online 2016 Aug 18. doi: 10.1016/j.cmet.2016.07.015

PMCID:: PMC5023486

Abstract Article PDF–3.1M

Select item 500779317.

The Zinc Finger of Prolyl Hydroxylase Domain Protein 2 Is Essential for Efficient Hydroxylation of Hypoxia-Inducible Factor α

Patrick R. Arsenault, Daisheng Song, Yu Jin Chung, Tejvir S. Khurana, Frank S. Lee

Mol Cell Biol. 2016 Sep 15; 36(18): 2328–2343. Prepublished online 2016 Jun 20. Published online 2016 Aug 26. doi: 10.1128/MCB.00090-16

PMCID:: PMC5007793

Abstract Article PDF–1.7M

Select item 491483418.

Regulation of the divalent metal ion transporter via membrane budding

KimberlyD Mackenzie, Natalie J Foot, Sushma Anand, Hazel E Dalton, Natasha Chaudhary, Brett M Collins, Suresh Mathivanan, Sharad Kumar

Cell Discov. 2016; 2: 16011. Published online 2016 Jun 21. doi: 10.1038/celldisc.2016.11

PMCID:: PMC4914834

Abstract Article PDF–3.1M

Select item 482214719.

Ndfip2 is a potential regulator of the iron transporter DMT1 in the liver

Natalie J. Foot, Kelly M. Gembus, Kimberly Mackenzie, Sharad Kumar

Sci Rep. 2016; 6: 24045. Published online 2016 Apr 6. doi: 10.1038/srep24045

PMCID:: PMC4822147

Abstract Article PDF–1.5M

Select item 460993320.

Intestinal DMT1 is critical for iron absorption in the mouse but is not required for the absorption of copper or manganese

Ali Shawki, Sarah R. Anthony, Yasuhiro Nose, Melinda A. Engevik, Eric J. Niespodzany, Tomasa Barrientos, Helena Öhrvik, Roger T. Worrell, Dennis J. Thiele, Bryan Mackenzie

Am J Physiol Gastrointest Liver Physiol. 2015 Oct 15; 309(8): G635–G647. Published online 2015 Aug 20. doi: 10.1152/ajpgi.00160.2015

PMCID:: PMC4609933

Abstract Article

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