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Select item 108724771.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107001382.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 105166423.

ISW1a modulates cohesin distribution in centromeric and pericentromeric regions

Ireneusz Litwin, Małgorzata Nowicka, Katarzyna Markowska, Ewa Maciaszczyk-Dziubińska, Paulina Tomaszewska, Robert Wysocki, Karol Kramarz

Nucleic Acids Res. 2023 Sep 22; 51(17): 9101–9121. Published online 2023 Jul 24. doi: 10.1093/nar/gkad612

PMCID:: PMC10516642

Abstract Article PDF–2.8M

Select item 96380284.

Yeast Smy2 and its human homologs GIGYF1 and -2 regulate Cdc48/VCP function during transcription stress

Michelle Harreman Lehner, Jane Walker, Kotryna Temcinaite, Anna Herlihy, Michael Taschner, Adam C. Berger, Anita H. Corbett, A. Barbara Dirac Svejstrup, Jesper Q. Svejstrup

Cell Rep. 2022 Oct 25; 41(4): 111536. Published online 2022 Oct 25. doi: 10.1016/j.celrep.2022.111536

PMCID:: PMC9638028

Abstract Article

Select item 96307925.

Mutations of Rad6 E2 ubiquitin-conjugating enzymes at alanine-126 in helix-3 affect ubiquitination activity and decrease enzyme stability

Prakash K. Shukla, Dhiraj Sinha, Andrew M. Leng, Jesse E. Bissell, Shravya Thatipamula, Rajarshi Ganguly, Kaitlin S. Radmall, Jack J. Skalicky, Dennis C. Shrieve, Mahesh B. Chandrasekharan

J Biol Chem. 2022 Nov; 298(11): 102524. Published online 2022 Sep 23. doi: 10.1016/j.jbc.2022.102524

PMCID:: PMC9630792

Abstract Article PDF–4.0M

Select item 92098116.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 87982257.

Structural insights into Ubr1 mediated N-degron polyubiquitination

Man Pan, Qingyun Zheng, Tian Wang, Lujun Liang, Junxiong Mao, Chong Zuo, Ruichao Ding, Huasong Ai, Yuan Xie, Dong Si, Yuanyuan Yu, Lei Liu, Minglei Zhao

Nature. Author manuscript; available in PMC 2022 Jan 28.

Published in final edited form as: Nature. 2021 Dec; 600(7888): 334–338. Published online 2021 Nov 17. doi: 10.1038/s41586-021-04097-8

PMCID:: PMC8798225

Abstract Article PDF–4.3M

Select item 84212048.

Investigation of RNA metabolism through large-scale genetic interaction profiling in yeast

Laurence Decourty, Christophe Malabat, Emmanuel Frachon, Alain Jacquier, Cosmin Saveanu

Nucleic Acids Res. 2021 Sep 7; 49(15): 8535–8555. Published online 2021 Aug 6. doi: 10.1093/nar/gkab680

PMCID:: PMC8421204

Abstract Article PDF–2.9M

Select item 81894359.

Timer-based proteomic profiling of the ubiquitin-proteasome system reveals a substrate receptor of the GID ubiquitin ligase

Ka-Yiu Edwin Kong, Bernd Fischer, Matthias Meurer, Ilia Kats, Zhaoyan Li, Frank Rühle, Joseph D. Barry, Daniel Kirrmaier, Veronika Chevyreva, Bryan-Joseph San Luis, Michael Costanzo, Wolfgang Huber, Brenda J. Andrews, Charles Boone, Michael Knop, Anton Khmelinskii

Mol Cell. 2021 Jun 3; 81(11): 2460–2476.e11. doi: 10.1016/j.molcel.2021.04.018

PMCID:: PMC8189435

Abstract Article

Select item 804571410.

Protein quality control degron-containing substrates are differentially targeted in the cytoplasm and nucleus by ubiquitin ligases

Christopher M Hickey, Carolyn Breckel, Mengwen Zhang, William C Theune, Mark Hochstrasser

Genetics. 2021 Jan; 217(1): 1–19. Published online 2020 Dec 22. doi: 10.1093/genetics/iyaa031

PMCID:: PMC8045714

Abstract Article PDF–2.3M

Select item 799398911.

A nuclear-based quality control pathway for non-imported mitochondrial proteins

Viplendra PS Shakya, William A Barbeau, Tianyao Xiao, Christina S Knutson, Max H Schuler, Adam L Hughes

eLife. 2021; 10: e61230. Published online 2021 Mar 18. doi: 10.7554/eLife.61230

PMCID:: PMC7993989

Abstract Article PDF–2.9M

Select item 794844812.

14-3-3 Protein Bmh1 triggers short-range compaction of mitotic chromosomes by recruiting sirtuin deacetylase Hst2

Neha Jain, Petra Janning, Heinz Neumann

J Biol Chem. 2021 Jan-Jun; 296: 100078. Published online 2020 Nov 23. doi: 10.1074/jbc.AC120.014758

PMCID:: PMC7948448

Abstract Article PDF–1.3M

Select item 792718613.

Direct involvement of Hsp70 ATP hydrolysis in Ubr1-dependent quality control

Amanjot Singh, Nidhi Vashistha, Jarrod Heck, Xin Tang, Peter Wipf, Jeffrey L. Brodsky, Randolph Y. Hampton

Mol Biol Cell. 2020 Nov 15; 31(24): 2669–2686. doi: 10.1091/mbc.E20-08-0541

PMCID:: PMC7927186

Abstract Article PDF–2.2M

Select item 786113214.

Loss of protein quality control gene UBR1 sensitizes Saccharomyces cerevisiae to the aminoglycoside hygromycin B

Avery M. Runnebohm, Melissa D. Evans, Adam E. Richardson, Samantha M. Turk, James B. Olesen, Philip J. Smaldino, Eric M. Rubenstein

Fine Focus. Author manuscript; available in PMC 2021 Feb 4.

Published in final edited form as: Fine Focus. 2020 Oct 26; 6(1): 76–83. doi: 10.33043/FF.6.1.76-83

PMCID:: PMC7861132

Abstract Article PDF–102K

Select item 775888015.

Purified Smc5/6 Complex Exhibits DNA Substrate Recognition and Compaction

Pilar Gutierrez-Escribano, Silvia Hormeño, Julene Madariaga-Marcos, Roger Solé-Soler, Francis J. O’Reilly, Kyle Morris, Clara Aicart-Ramos, Ricardo Aramayo, Alex Montoya, Holger Kramer, Juri Rappsilber, Jordi Torres-Rosell, Fernando Moreno-Herrero, Luis Aragon

Mol Cell. 2020 Dec 17; 80(6): 1039–1054.e6. doi: 10.1016/j.molcel.2020.11.012

PMCID:: PMC7758880

Abstract Article

Select item 772147516.

A Selective Autophagy Pathway for Phase-Separated Endocytic Protein Deposits

Florian Wilfling, Chia-Wei Lee, Philipp S. Erdmann, Yumei Zheng, Dawafuti Sherpa, Stefan Jentsch, Boris Pfander, Brenda A. Schulman, Wolfgang Baumeister

Mol Cell. 2020 Dec 3; 80(5): 764–778.e7. doi: 10.1016/j.molcel.2020.10.030