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Select item 111136111.

E3 ubiquitin ligase RNF13 involves spatial learning and assembly of the SNARE complex

Qiang Zhang, Yanfeng Li, Lei Zhang, Nan Yang, Jiao Meng, Pingping Zuo, Yong Zhang, Jie Chen, Li Wang, Xiang Gao, Dahai Zhu

Cell Mol Life Sci. 2013 Jan; 70(1): 153–165. Published online 2012 Aug 14. doi: 10.1007/s00018-012-1103-5

PMCID:: PMC11113611

Abstract Article PDF–888K

Select item 111094832.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 105093113.

KIAA0317 regulates SOCS1 stability to ameliorate colonic inflammation

Karina C. Lockwood, Travis B. Lear, Shristi Rajbhandari, Alison C. McKelvey, Sarah R. Dunn, Áine N. Boudreau, Yuan Liu, Bill B. Chen

FEBS J. Author manuscript; available in PMC 2023 Sep 28.

Published in final edited form as: FEBS J. 2023 Aug; 290(15): 3802–3811. Published online 2023 Apr 7. doi: 10.1111/febs.16780

PMCID:: PMC10509311

Abstract Article PDF–1.6M

Select item 104762814.

The CUL4B‐based E3 ubiquitin ligase regulates mitosis and brain development by recruiting phospho‐specific DCAFs

Anna Stier, Samuel Gilberto, Weaam I Mohamed, Lars N Royall, Jonne Helenius, Ivan Mikicic, Tatjana Sajic, Petra Beli, Daniel J Müller, Sebastian Jessberger, Matthias Peter

EMBO J. 2023 Sep; 42(17): e112847. Published online 2023 Jun 27. doi: 10.15252/embj.2022112847

PMCID:: PMC10476281

Abstract Article PDF–2.6M

Select item 104700785.

Hyperubiquitylation of DNA helicase RECQL4 by E3 ligase MITOL prevents mitochondrial entry and potentiates mitophagy

Mansoor Hussain, Aftab Mohammed, Shabnam Saifi, Swati Priya, Sagar Sengupta

J Biol Chem. 2023 Sep; 299(9): 105087. Published online 2023 Jul 24. doi: 10.1016/j.jbc.2023.105087

PMCID:: PMC10470078

Abstract Article PDF–5.1M

Select item 104258426.

Cryo‐EM structure of the chain‐elongating E3 ubiquitin ligase UBR5

Zuzana Hodáková, Irina Grishkovskaya, Hanna L Brunner, Derek L Bolhuis, Katarina Belačić, Alexander Schleiffer, Harald Kotisch, Nicholas G Brown, David Haselbach

EMBO J. 2023 Aug; 42(16): e113348. Published online 2023 Jul 6. doi: 10.15252/embj.2022113348

PMCID:: PMC10425842

Abstract Article PDF–3.0M

Select item 103180117.

SIRT1 ubiquitination is regulated by opposing activities of APC/C-Cdh1 and AROS during stress-induced premature senescence

Sang Hyup Lee, Ji-Hye Yang, Ui-Hyun Park, Hanbyeul Choi, Yoo Sung Kim, Bo-Eun Yoon, Hye-Jeong Han, Hyun-Taek Kim, Soo-Jong Um, Eun-Joo Kim

Exp Mol Med. 2023 Jun; 55(6): 1232–1246. Published online 2023 Jun 1. doi: 10.1038/s12276-023-01012-1

PMCID:: PMC10318011

Abstract Article PDF–4.5M

Select item 102852698.

Inflammasome activation and metabolic remodelling in p16‐positive aging cells aggravates high‐fat diet‐induced lung fibrosis by inhibiting NEDD4L‐mediated K48‐polyubiquitin‐dependent degradation of SGK1

Xin Gu, Haoyu Meng, Chengyi Peng, Shiyu Lin, Baihong Li, Lin Zhao, Xue Yang, Guangyan Wang, Wenyuan Cai, Jiawen Zhou, Shuiyuan Liu, Peng Wu, Yingqiang Du, Jianliang Jin, Xiaoyan Wang

Clin Transl Med. 2023 Jun; 13(6): e1308. Published online 2023 Jun 21. doi: 10.1002/ctm2.1308

PMCID:: PMC10285269

Abstract Article PDF–20M

Select item 102628119.

TRIM7/RNF90 promotes autophagy via regulation of ATG7 ubiquitination during L. monocytogenes infection

Jie Wang, Xiao Qin, Yulu Huang, Qunmei Zhang, Jinyong Pei, Yi Wang, Idan Goren, Shujun Ma, Zhishan Song, Yanzi Liu, Hongxia Xing, Hui Wang, Bo Yang

Autophagy. 2023; 19(6): 1844–1862. Published online 2023 Jan 1. doi: 10.1080/15548627.2022.2162706

PMCID:: PMC10262811

Abstract Article PDF–7.7M

Select item 1023410710.

The E2 ubiquitin-conjugating enzymes UBE2D1 and UBE2D2 regulate VEGFR2 dynamics and endothelial function

William R. Critchley, Gina A. Smith, Ian C. Zachary, Michael A. Harrison, Sreenivasan Ponnambalam

J Cell Sci. 2023 May 15; 136(10): jcs260657. Published online 2023 May 25. doi: 10.1242/jcs.260657

PMCID:: PMC10234107

Abstract Article

Select item 1020916911.

A ZFYVE21-Rubicon-RNF34 signaling complex promotes endosome-associated inflammasome activity in endothelial cells

Xue Li, Quan Jiang, Guiyu Song, Mahsa Nouri Barkestani, Qianxun Wang, Shaoxun Wang, Matthew Fan, Caodi Fang, Bo Jiang, Justin Johnson, Arnar Geirsson, George Tellides, Jordan S. Pober, Dan Jane-wit

Nat Commun. 2023; 14: 3002. Published online 2023 May 24. doi: 10.1038/s41467-023-38684-2

Correction in:: Nat Commun. 2023; 14: 3336.

Correction in:: Nat Commun. 2023; 14: 8404.

PMCID:: PMC10209169

Abstract Article PDF–4.2M

Select item 1020429312.

S100A6 inhibits MDM2 to suppress breast cancer growth and enhance sensitivity to chemotherapy

Mengxin Qi, Xianglan Yi, Baohui Yue, Mingxiang Huang, Sheng Zhou, Jing Xiong

Breast Cancer Res. 2023; 25: 55. Published online 2023 May 22. doi: 10.1186/s13058-023-01657-w

PMCID:: PMC10204293

Abstract Article PDF–10M

Select item 1019396013.

TRAF4-mediated nonproteolytic ubiquitination of androgen receptor promotes castration-resistant prostate cancer

Ramesh Singh, Huan Meng, Tao Shen, Lance Edward V. Lumahan, Steven Nguyen, Hong Shen, Subhamoy Dasgupta, Li Qin, Dileep Karri, Bokai Zhu, Feng Yang, Cristian Coarfa, Bert W. O’Malley, Ping Yi

Proc Natl Acad Sci U S A. 2023 May 16; 120(20): e2218229120. Published online 2023 May 8. doi: 10.1073/pnas.2218229120

PMCID:: PMC10193960

Abstract Article PDF–4.1M

Select item 1008090814.

The UAS thioredoxin-like domain of UBXN7 regulates E3 ubiquitin ligase activity of RNF111/Arkadia

Sadek Amhaz, Batiste Boëda, Mouna Chouchène, Sabrina Colasse, Florent Dingli, Damarys Loew, Julien Henri, Céline Prunier, Laurence Levy

BMC Biol. 2023; 21: 73. Published online 2023 Apr 7. doi: 10.1186/s12915-023-01576-4

PMCID:: PMC10080908

Abstract Article PDF–3.2M

Select item 1007043815.

E3 ligase RNF99 negatively regulates TLR-mediated inflammatory immune response via K48-linked ubiquitination of TAB2

Jie Zhang, Lei Cao, Amy Gao, Ruiqing Ren, Liwen Yu, Qian Li, Yapeng Liu, Wenqian Qi, Yonghao Hou, Wenhai Sui, Guohai Su, Yun Zhang, Cheng Zhang, Meng Zhang

Cell Death Differ. 2023 Apr; 30(4): 966–978. Published online 2023 Jan 21. doi: 10.1038/s41418-023-01115-2

PMCID:: PMC10070438

Abstract Article PDF–11M

Select item 1003393716.

Assessment of community efforts to advance network-based prediction of protein–protein interactions

Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu

Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7

PMCID:: PMC10033937

Abstract Article PDF–1.5M

Select item 995044617.

SPOP mutations promote tumor immune escape in endometrial cancer via the IRF1–PD-L1 axis

Kun Gao, Qing Shi, Ye Gu, Wanqi Yang, Yuanlong He, Zeheng Lv, Yan Ding, Wenxin Cao, Chenji Wang, Xiaoping Wan

Cell Death Differ. 2023 Feb; 30(2): 475–487. Published online 2022 Dec 8. doi: 10.1038/s41418-022-01097-7

PMCID:: PMC9950446

Abstract Article PDF–4.9M

Select item 988839318.

PD-L1 translocation to the plasma membrane enables tumor immune evasion through MIB2 ubiquitination

Xinfang Yu, Wei Li, Haidan Liu, Xu Wang, Cristian Coarfa, Chao Cheng, Xinlian Yu, Zhaoyang Zeng, Ya Cao, Ken H. Young, Yong Li

J Clin Invest. 2023 Feb 1; 133(3): e160456. Published online 2023 Feb 1. doi: 10.1172/JCI160456

PMCID:: PMC9888393

Abstract Article PDF–5.0M

Select item 988326119.

Phosphorylation of OTUB1 at Tyr 26 stabilizes the mTORC1 component, Raptor

Seung Un Seo, Seon Min Woo, Min Wook Kim, Eun-Woo Lee, Kyoung-jin Min, Taeg Kyu Kwon

Cell Death Differ. 2023 Jan; 30(1): 82–93. Published online 2022 Aug 4. doi: 10.1038/s41418-022-01047-3

PMCID:: PMC9883261

Abstract Article PDF–4.6M

Select item 986049620.

Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid–liquid phase separation–based method

Ryota Hayashida, Reika Kikuchi, Kenichiro Imai, Waka Kojima, Tatsuya Yamada, Miho Iijima, Hiromi Sesaki, Keiji Tanaka, Noriyuki Matsuda, Koji Yamano

J Biol Chem. 2023 Feb; 299(2): 102822. Published online 2022 Dec 21. doi: 10.1016/j.jbc.2022.102822

PMCID:: PMC9860496

Abstract Article PDF–6.6M

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