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Select item 99820731.

ETV2 Upregulation Marks the Specification of Early Cardiomyocytes and Endothelial Cells During Co-differentiation

Xu Cao, Maria Mircea, Gopala Krishna Yakala, Francijna E van den Hil, Marcella Brescia, Hailiang Mei, Christine L Mummery, Stefan Semrau, Valeria V Orlova

Stem Cells. 2023 Feb; 41(2): 140–152. Published online 2022 Dec 13. doi: 10.1093/stmcls/sxac086

PMCID:: PMC9982073

Abstract Article PDF–31M

Select item 93043412.

Etv2 regulates enhancer chromatin status to initiate Shh expression in the limb bud

Naoko Koyano-Nakagawa, Wuming Gong, Satyabrata Das, Joshua W. M. Theisen, Tran B. Swanholm, Daniel Van Ly, Nikita Dsouza, Bhairab N. Singh, Hiroko Kawakami, Samantha Young, Katherine Q. Chen, Yasuhiko Kawakami, Daniel J. Garry

Nat Commun. 2022; 13: 4221. Published online 2022 Jul 21. doi: 10.1038/s41467-022-31848-6

PMCID:: PMC9304341

Abstract Article PDF–5.7M

Select item 92031293.

Differential Etv2 threshold requirement for endothelial and erythropoietic development

Tanvi Sinha, Kelly Lammerts van Bueren, Diane E. Dickel, Ivana Zlatanova, Reuben Thomas, Carlos O. Lizama, Shan-Mei Xu, Ann C. Zovein, Kohta Ikegami, Ivan P. Moskowitz, Katherine S. Pollard, Len A. Pennacchio, Brian L. Black

Cell Rep. Author manuscript; available in PMC 2022 Jun 16.

Published in final edited form as: Cell Rep. 2022 May 31; 39(9): 110881. doi: 10.1016/j.celrep.2022.110881

PMCID:: PMC9203129

Abstract Article PDF–2.0M

Select item 82529624.

Dual role of endothelial Myct1 in tumor angiogenesis and tumor immunity

Ashraf Ul Kabir, Madhav Subramanian, Dong Hun Lee, Xiaoli Wang, Karen Krchma, Jun Wu, Teri Naismith, Carmen M. Halabi, Ju Young Kim, Fadi E. Pulous, Brian G. Petrich, Suhyun Kim, Hae-Chul Park, Phyllis I. Hanson, Hua Pan, Samuel A. Wickline, Daved H. Fremont, Changwon Park, Kyunghee Choi

Sci Transl Med. Author manuscript; available in PMC 2021 Sep 3.

Published in final edited form as: Sci Transl Med. 2021 Mar 3; 13(583): eabb6731. doi: 10.1126/scitranslmed.abb6731

PMCID:: PMC8252962

Abstract Article PDF–4.3M

Select item 76103815.

The T-box Transcription Factor Eomesodermin Governs Hemogenic Competence of Yolk-Sac Mesodermal Progenitors

Luke T.G. Harland, Claire S. Simon, Anna D. Senft, Ita Costello, Lucas Greder, Ivan Imaz-Rosshandler, Berthold Gottgens, John C. Marioni, Elizabeth K. Bikoff, Catherine Porcher, Marella de Bruijn, Elizabeth J. Robertson

Nat Cell Biol. Author manuscript; available in PMC 2021 Mar 23.

Published in final edited form as: Nat Cell Biol. 2021 Jan 1; 23(1): 61–74. Published online 2021 Jan 8. doi: 10.1038/s41556-020-00611-8

Correction in:: Nat Cell Biol. 2021 Feb 11

PMCID:: PMC7610381

Abstract Article PDF–12M

Select item 66977516.

Endocardium differentiation through Sox17 expression in endocardium precursor cells regulates heart development in mice

Rie Saba, Keiko Kitajima, Lucille Rainbow, Silvia Engert, Mami Uemura, Hidekazu Ishida, Ioannis Kokkinopoulos, Yasunori Shintani, Shigeru Miyagawa, Yoshiakira Kanai, Masami Kanai-Azuma, Peter Koopman, Chikara Meno, John Kenny, Heiko Lickert, Yumiko Saga, Ken Suzuki, Yoshiki Sawa, Kenta Yashiro

Sci Rep. 2019; 9: 11953. Published online 2019 Aug 16. doi: 10.1038/s41598-019-48321-y

PMCID:: PMC6697751

Abstract Article PDF–6.2M

Select item 66118067.

Etv2 transcriptionally regulates Yes1 and promotes cell proliferation during embryogenesis

Bhairab N. Singh, Wuming Gong, Satyabrata Das, Joshua W. M. Theisen, Javier E. Sierra-Pagan, Demetris Yannopoulos, Erik Skie, Pruthvi Shah, Mary G. Garry, Daniel J. Garry

Sci Rep. 2019; 9: 9736. Published online 2019 Jul 5. doi: 10.1038/s41598-019-45841-5

PMCID:: PMC6611806

Abstract Article PDF–4.4M

Select item 59610838.

Dysregulation of TBX1 dosage in the anterior heart field results in congenital heart disease resembling the 22q11.2 duplication syndrome

Erica Hasten, Donna M McDonald-McGinn, Terrence B Crowley, Elaine Zackai, Beverly S Emanuel, Bernice E Morrow, Silvia E Racedo

Hum Mol Genet. 2018 Jun 1; 27(11): 1847–1857. Published online 2018 Mar 2. doi: 10.1093/hmg/ddy078

PMCID:: PMC5961083

Abstract Article PDF–1.3M

Select item 57267249.

Etv2-miR-130a-Jarid2 cascade regulates vascular patterning during embryogenesis

Bhairab N. Singh, Naoyuki Tahara, Yasuhiko Kawakami, Satyabrata Das, Naoko Koyano-Nakagawa, Wuming Gong, Mary G. Garry, Daniel J. Garry

PLoS One. 2017; 12(12): e0189010. Published online 2017 Dec 12. doi: 10.1371/journal.pone.0189010

PMCID:: PMC5726724

Abstract Article PDF–8.7M

Select item 559951510.

A CRISPR screen identifies genes controlling Etv2 threshold expression in murine hemangiogenic fate commitment

Haiyong Zhao, Kyunghee Choi

Nat Commun. 2017; 8: 541. Published online 2017 Sep 14. doi: 10.1038/s41467-017-00667-5

PMCID:: PMC5599515

Abstract Article PDF–3.0M

Select item 559926611.

Embryonic Stem Cell Differentiation to Functional Arterial Endothelial Cells through Sequential Activation of ETV2 and NOTCH1 Signaling by HIF1α

Kit Man Tsang, James S. Hyun, Kwong Tai Cheng, Micaela Vargas, Dolly Mehta, Masuko Ushio-Fukai, Li Zou, Kostandin V. Pajcini, Jalees Rehman, Asrar B. Malik

Stem Cell Reports. 2017 Sep 12; 9(3): 796–806. Published online 2017 Aug 3. doi: 10.1016/j.stemcr.2017.07.001

PMCID:: PMC5599266

Abstract Article PDF–2.8M

Select item 546099512.

ETV2/ER71 regulates hematopoietic regeneration by promoting hematopoietic stem cell proliferation

Can-Xin Xu, Tae-Jin Lee, Nagisa Sakurai, Karen Krchma, Fang Liu, Daofeng Li, Ting Wang, Kyunghee Choi

J Exp Med. 2017 Jun 5; 214(6): 1643–1653. doi: 10.1084/jem.20160923

PMCID:: PMC5460995

Abstract Article PDF–1.5M

Select item 538630113.

Reduced dosage of β-catenin provides significant rescue of cardiac outflow tract anomalies in a Tbx1 conditional null mouse model of 22q11.2 deletion syndrome

Silvia E. Racedo, Erica Hasten, Mingyan Lin, Gnanapackiam Sheela Devakanmalai, Tingwei Guo, Ertugrul M. Ozbudak, Chen-Leng Cai, Deyou Zheng, Bernice E. Morrow

PLoS Genet. 2017 Mar; 13(3): e1006687. Published online 2017 Mar 27. doi: 10.1371/journal.pgen.1006687

PMCID:: PMC5386301

Abstract Article PDF–3.3M

Select item 490637014.

The Hemogenic Competence of Endothelial Progenitors Is Restricted by Runx1 Silencing during Embryonic Development

Alexia Eliades, Sarah Wareing, Elli Marinopoulou, Muhammad Z.H. Fadlullah, Rahima Patel, Joanna B. Grabarek, Berenika Plusa, Georges Lacaud, Valerie Kouskoff

Cell Rep. 2016 Jun 7; 15(10): 2185–2199. Published online 2016 May 26. doi: 10.1016/j.celrep.2016.05.001

PMCID:: PMC4906370

Abstract Article

Select item 474724015.

Etv2-miR-130a network regulates mesodermal specification

Bhairab N. Singh, Yasuhiko Kawakami, Ryutaro Akiyama, Tara L. Rasmussen, Mary G. Garry, Wuming Gong, Satyabrata Das, Xiaozhong Shi, Naoko Koyano-Nakagawa, Daniel J. Garry

Cell Rep. Author manuscript; available in PMC 2016 Feb 9.

Published in final edited form as: Cell Rep. 2015 Nov 3; 13(5): 915–923. Published online 2015 Oct 22. doi: 10.1016/j.celrep.2015.09.060

PMCID:: PMC4747240

Abstract Article PDF–1.6M

Select item 469699316.

The ETS Factor, ETV2: a Master Regulator for Vascular Endothelial Cell Development

Se-Yeong Oh, Ju Young Kim, Changwon Park

Mol Cells. 2015 Dec 31; 38(12): 1029–1036. Published online 2015 Dec 21. doi: 10.14348/molcells.2015.0331

PMCID:: PMC4696993

Abstract Article PDF–498K

Select item 469081217.

Injury mediated vascular regeneration requires endothelial ER71/ETV2

Changwon Park, Tae-Jin Lee, Suk Ho Bhang, Fang Liu, Rei Nakamura, Sunday S. Oladipupo, Ian Pitha-Rowe, Benjamin Capoccia, Hong Seo Choi, Tae Min Kim, Norifumi Urao, Masuko Ushio-Fukai, Dong Jun Lee, Hiroyuki Miyoshi, Byung-Soo Kim, Dae-Sik Lim, Rajendra S. Apte, David M. Ornitz, Kyunghee Choi

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2017 Jan 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Jan; 36(1): 86–96. Published online 2015 Nov 19. doi: 10.1161/ATVBAHA.115.306430

PMCID:: PMC4690812

Abstract Article PDF–3.6M

Select item 465367018.

Feedback Mechanisms Regulate Ets Variant 2 (Etv2) Gene Expression and Hematoendothelial Lineages

Naoko Koyano-Nakagawa, Xiaozhong Shi, Tara L. Rasmussen, Satyabrata Das, Camille A. Walter, Daniel J. Garry

J Biol Chem. 2015 Nov 20; 290(47): 28107–28119. Published online 2015 Sep 22. doi: 10.1074/jbc.M115.662197

PMCID:: PMC4653670

Abstract Article PDF–1.5M

Select item 442804519.

Induction of hematopoietic and endothelial cell program orchestrated by ETS transcription factor ER71/ETV2

Fang Liu, Daofeng Li, Yik Yeung Lawrence Yu, Inyoung Kang, Min-Ji Cha, Ju Young Kim, Changwon Park, Dennis K Watson, Ting Wang, Kyunghee Choi

EMBO Rep. 2015 May; 16(5): 654–669. Published online 2015 Mar 23. doi: 10.15252/embr.201439939

PMCID:: PMC4428045

Abstract Article PDF–4.1M

Select item 439226420.

The Transcription Factor Mesp1 Interacts with cAMP-responsive Element Binding Protein 1 (Creb1) and Coactivates Ets Variant 2 (Etv2) Gene Expression

Xiaozhong Shi, Katie M. Zirbes, Tara L. Rasmussen, Anwarul Ferdous, Mary G. Garry, Naoko Koyano-Nakagawa, Daniel J. Garry

J Biol Chem. 2015 Apr 10; 290(15): 9614–9625. Published online 2015 Feb 18. doi: 10.1074/jbc.M114.614628

PMCID:: PMC4392264

Abstract Article PDF–2.3M

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