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Items: 1 to 20 of 58

1.
Dual treatment with kynurenine pathway inhibitors and NAD+ precursors synergistically extends life span in Drosophila
Mariann M. Gabrawy, Reyhan Westbrook, Austin King, Nick Khosravian, Neeraj Ochaney, Tagide DeCarvalho, Qinchuan Wang, Yuqiong Yu, Qiao Huang, Adam Said, Michael Abadir, Cissy Zhang, Pratik Khare, Jennifer E. Fairman, Anne Le, Ginger L. Milne, Fernando J. Vonhoff, Jeremy D. Walston, Peter M. Abadir
Aging Cell. 2024 Apr; 23(4): e14102. Published online 2024 Mar 13. doi: 10.1111/acel.14102
PMCID:
PMC11019140
AbstractArticlePDF–6.5M
2.
dTrmt10A impacts Hsp70 chaperone m6A levels and the stress response in the Drosophila brain
Alexandra E. Perlegos, Xiuming Quan, Kirby M. Donnelly, Hui Shen, Emily J. Shields, Heidi Elashal, Kathy Fange Liu, Nancy M. Bonini
Sci Rep. 2023; 13: 22999. Published online 2023 Dec 28. doi: 10.1038/s41598-023-50272-4
PMCID:
PMC10754819
AbstractArticlePDF–2.6M
3.
N6-Methyladenine Progressively Accumulates in Mitochondrial DNA during Aging
Ádám Sturm, Himani Sharma, Ferenc Bodnár, Maryam Aslam, Tibor Kovács, Ákos Németh, Bernadette Hotzi, Viktor Billes, Tímea Sigmond, Kitti Tátrai, Balázs Egyed, Blanka Téglás-Huszár, Gitta Schlosser, Nikolaos Charmpilas, Christina Ploumi, András Perczel, Nektarios Tavernarakis, Tibor Vellai
Int J Mol Sci. 2023 Oct; 24(19): 14858. Published online 2023 Oct 3. doi: 10.3390/ijms241914858
PMCID:
PMC10573865
AbstractArticlePDF–3.6M
4.
Stress-induced reversible cell-cycle arrest requires PRC2/PRC1-mediated control of mitophagy in Drosophila germline stem cells and human iPSCs
Tommy H. Taslim, Abdiasis M. Hussein, Riya Keshri, Julien R. Ishibashi, Tung C. Chan, Bich N. Nguyen, Shuozhi Liu, Daniel Brewer, Stuart Harper, Scott Lyons, Ben Garver, Jimmy Dang, Nanditaa Balachandar, Samriddhi Jhajharia, Debra del Castillo, Julie Mathieu, Hannele Ruohola-Baker
Stem Cell Reports. 2023 Jan 10; 18(1): 269–288. Published online 2022 Dec 8. doi: 10.1016/j.stemcr.2022.11.004
PMCID:
PMC9860083
AbstractArticlePDF–6.8M
5.
Beneficial commensal bacteria promote Drosophila growth by downregulating the expression of peptidoglycan recognition proteins
Marialaura Gallo, Justin M. Vento, Pauline Joncour, Andrea Quagliariello, Elisa Maritan, Nuno F. Silva-Soares, Matteo Battistolli, Chase L. Beisel, Maria Elena Martino
iScience. 2022 Jun 17; 25(6): 104357. Published online 2022 May 5. doi: 10.1016/j.isci.2022.104357
PMCID:
PMC9121327
AbstractArticlePDF–1.9M
6.
Evidence of Adaptive Evolution in Wolbachia-Regulated Gene DNMT2 and Its Role in the Dipteran Immune Response and Pathogen Blocking
Tamanash Bhattacharya, Danny W. Rice, John M. Crawford, Richard W. Hardy, Irene L. G. Newton
Viruses. 2021 Aug; 13(8): 1464. Published online 2021 Jul 27. doi: 10.3390/v13081464
PMCID:
PMC8402854
AbstractArticlePDF–2.8M
7.
Epigenetic Regulation of ALS and CMT: A Lesson from Drosophila Models
Masamitsu Yamaguchi, Kentaro Omori, Satoshi Asada, Hideki Yoshida
Int J Mol Sci. 2021 Jan; 22(2): 491. Published online 2021 Jan 6. doi: 10.3390/ijms22020491
PMCID:
PMC7825332
AbstractArticlePDF–400K
8.
Ten-eleven translocation proteins and their role beyond DNA demethylation – what we can learn from the fly
Joy N. Ismail, Mirna Ghannam, Amani Al Outa, Felice Frey, Margret Shirinian
Epigenetics. 2020; 15(11): 1139–1150. Published online 2020 May 18. doi: 10.1080/15592294.2020.1767323
PMCID:
PMC7595634
AbstractArticlePDF–2.5M
9.
Drosophila DNA/RNA methyltransferase contributes to robust host defense in ageing animals by regulating sphingolipid metabolism
Varada Abhyankar, Bhagyashree Kaduskar, Siddhesh S. Kamat, Deepti Deobagkar, Girish S Ratnaparkhi
J Exp Biol. Author manuscript; available in PMC 2019 May 16.
Published in final edited form as: J Exp Biol. 2018 Nov 16; 221(Pt 22): jeb187989. Published online 2018 Nov 16. doi: 10.1242/jeb.187989
PMCID:
PMC6258898
AbstractArticlePDF–1.6M
10.
Comparative Transcriptomics in Two Extreme Neopterans Reveals General Trends in the Evolution of Modern Insects
Guillem Ylla, Maria-Dolors Piulachs, Xavier Belles
iScience. 2018 Jun 29; 4: 164–179. Published online 2018 May 28. doi: 10.1016/j.isci.2018.05.017
PMCID:
PMC6147021
AbstractArticlePDF–13M
11.
Levels of DNA cytosine methylation in the Drosophila genome
Saniya Deshmukh, VK Chaithanya Ponnaluri, Nan Dai, Sriharsa Pradhan, Deepti Deobagkar
PeerJ. 2018; 6: e5119. Published online 2018 Jul 2. doi: 10.7717/peerj.5119
PMCID:
PMC6033079
AbstractArticlePDF–6.0M
12.
Evolution of DNMT2 in drosophilids: Evidence for positive and purifying selection and insights into new protein (pathways) interactions
Gilberto Cavalheiro Vieira, Marícia Fantinel D’Ávila, Rebeca Zanini, Maríndia Deprá, Vera Lúcia da Silva Valente
Genet Mol Biol. 2018; 41(1 Suppl 1): 215–234. Published online 2018 Mar 26. doi: 10.1590/1678-4685-GMB-2017-0056
PMCID:
PMC5913717
AbstractArticlePDF–6.2M
13.
The Emerging Field of Epitranscriptomics in Neurodevelopmental and Neuronal Disorders
Margarita T. Angelova, Dilyana G. Dimitrova, Nadja Dinges, Tina Lence, Lina Worpenberg, Clément Carré, Jean-Yves Roignant
Front Bioeng Biotechnol. 2018; 6: 46. Published online 2018 Apr 13. doi: 10.3389/fbioe.2018.00046
PMCID:
PMC5908907
AbstractArticlePDF–1.2M
14.
Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species
Piero Sanfilippo, Jiayu Wen, Eric C. Lai
Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0
PMCID:
PMC5707805
AbstractArticlePDF–3.2M
15.
Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster
Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira
RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117
PMCID:
PMC5689002
AbstractArticlePDF–4.0M
16.
Wolbachia elevates host methyltransferase expression to block an RNA virus early during infection
Tamanash Bhattacharya, Irene L. G. Newton, Richard W. Hardy
PLoS Pathog. 2017 Jun; 13(6): e1006427. Published online 2017 Jun 15. doi: 10.1371/journal.ppat.1006427
PMCID:
PMC5472326
AbstractArticlePDF–2.6M
17.
Linking epigenetic function to electrostatics: The DNMT2 structural model example
Gilberto Cavalheiro Vieira, Gustavo Fioravanti Vieira, Marialva Sinigaglia, Vera Lúcia da Silva Valente
PLoS One. 2017; 12(6): e0178643. Published online 2017 Jun 2. doi: 10.1371/journal.pone.0178643
PMCID:
PMC5456315
AbstractArticlePDF–12M
18.
Functional screening of mammalian mechanosensitive genes using Drosophila RNAi library– Smarcd3/Bap60 is a mechanosensitive pro-inflammatory gene
Sandeep Kumar, In-hwan Jang, Chan Woo Kim, Dong-Won Kang, Won Jae Lee, Hanjoong Jo
Sci Rep. 2016; 6: 36461. Published online 2016 Nov 7. doi: 10.1038/srep36461
PMCID:
PMC5098218
AbstractArticlePDF–1.6M
19.
Tissue-specific down-regulation of S-adenosyl-homocysteine via suppression of dAhcyL1/dAhcyL2 extends health span and life span in Drosophila
Andrey A. Parkhitko, Richard Binari, Nannan Zhang, John M. Asara, Fabio Demontis, Norbert Perrimon
Genes Dev. 2016 Jun 15; 30(12): 1409–1422. doi: 10.1101/gad.282277.116
PMCID:
PMC4926864
AbstractArticlePDF–1.4M
20.
Disruption of Methionine Metabolism in Drosophila melanogaster Impacts Histone Methylation and Results in Loss of Viability
Mengying Liu, Valerie L. Barnes, Lori A. Pile
G3 (Bethesda) 2016 Jan; 6(1): 121–132. Published online 2015 Nov 6. doi: 10.1534/g3.115.024273
PMCID:
PMC4704710
AbstractArticlePDF–1.5M

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