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Select item 107875421.

Chromatin accessibility complex subunit 1 enhances tumor growth by regulating the oncogenic transcription of YAP in breast and cervical cancer

Shasha Li, Lulu Wang, Jing Shi, Yi Chen, Ang Xiao, Bingyue Huo, Wenjing Tian, Shilu Zhang, Gang Yang, Wensheng Gong, Huixia Zhang

PeerJ. 2024; 12: e16752. Published online 2024 Jan 10. doi: 10.7717/peerj.16752

PMCID:: PMC10787542

Abstract Article PDF–13M

Select item 104805352.

Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex

Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté

J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123

PMCID:: PMC10480535

Abstract Article PDF–2.4M

Select item 101580293.

S100 Calcium Binding Protein A16 Promotes Cell Proliferation by triggering LATS1 ubiquitin degradation mediated by CUL4A ligase to inhibit Hippo pathway in Glioma development

Yifang Hu, Rihua Zhang, Shan Lu, Wensong Zhang, Dan Wang, Yaoqi Ge, Feng Jiang, Xiaoxuan Qin, Yun Liu

Int J Biol Sci. 2023; 19(7): 2034–2052. Published online 2023 Apr 2. doi: 10.7150/ijbs.79924

PMCID:: PMC10158029

Abstract Article PDF–7.9M

Select item 100729064.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 99385515.

WWP2 drives the progression of gastric cancer by facilitating the ubiquitination and degradation of LATS1 protein

Jianping Zou, Ling Zhou, Yi Le, Zhi Fang, Min Zhong, Fengting Nie, Xianpin Wei, Xiaomei Zhang, Zhen Chen, Lingling Cai, Heng Wang, Jianping Xiong, Ziling Fang, Xiaojun Xiang

Cell Commun Signal. 2023; 21: 38. Published online 2023 Feb 17. doi: 10.1186/s12964-023-01050-2

PMCID:: PMC9938551

Abstract Article PDF–11M

Select item 97054396.

Inactivation of LATS1/2 drives luminal-basal plasticity to initiate basal-like mammary carcinomas

Joseph G. Kern, Andrew M. Tilston-Lunel, Anthony Federico, Boting Ning, Amy Mueller, Grace B. Peppler, Eleni Stampouloglou, Nan Cheng, Randy L. Johnson, Marc E. Lenburg, Jennifer E. Beane, Stefano Monti, Xaralabos Varelas

Nat Commun. 2022; 13: 7198. Published online 2022 Nov 28. doi: 10.1038/s41467-022-34864-8

PMCID:: PMC9705439

Abstract Article PDF–6.2M

Select item 94347057.

Proteasomal down-regulation of the proapoptotic MST2 pathway contributes to BRAF inhibitor resistance in melanoma

David Romano, Lucía García-Gutiérrez, Nourhan Aboud, David J Duffy, Keith T Flaherty, Dennie T Frederick, Walter Kolch, David Matallanas

Life Sci Alliance. 2022 Oct; 5(10): e202201445. Published online 2022 Aug 29. doi: 10.26508/lsa.202201445

PMCID:: PMC9434705

Abstract Article PDF–2.0M

Select item 94023078.

TRIM65 Promotes Malignant Cell Behaviors in Triple-Negative Breast Cancer by Impairing the Stability of LATS1 Protein

Yongbin Lu, Yi Xiao, Jingru Yang, Hongxin Su, Xiaobin Zhang, Fei Su, Baohong Tian, Da Zhao, Xiaoling Ling, Tao Zhang

Oxid Med Cell Longev. 2022; 2022: 4374978. Published online 2022 Aug 17. doi: 10.1155/2022/4374978

PMCID:: PMC9402307

Abstract Article PDF–3.2M

Select item 93604439.

Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner

Lucía García-Gutiérrez, Emma Fallahi, Nourhan Aboud, Niall Quinn, David Matallanas

Cell Death Dis. 2022 Aug; 13(8): 692. Published online 2022 Aug 8. doi: 10.1038/s41419-022-05147-3

PMCID:: PMC9360443

Abstract Article PDF–5.8M

Select item 930062310.

LATS kinases and SLUG regulate the transition to advanced stage in aggressive oral cancer cells

Emi Fujibayashi, Satomi Mukai, Kosuke Torigata, Yumi Ando, Toshihiro Uchihashi, Masami Nozaki, Susumu Tanaka, Masato Okada, Mikihiko Kogo, Hiroshi Nojima, Norikazu Yabuta

Sci Rep. 2022; 12: 12363. Published online 2022 Jul 20. doi: 10.1038/s41598-022-16667-5

PMCID:: PMC9300623

Abstract Article PDF–12M

Select item 911973611.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 902328612.

Oxidative stress-CBP axis modulates MOB1 acetylation and activates the Hippo signaling pathway

Jiaqi Jin, Lei Zhang, Xueying Li, Weizhi Xu, Siyuan Yang, Jiagui Song, Wenhao Zhang, Jun Zhan, Jianyuan Luo, Hongquan Zhang

Nucleic Acids Res. 2022 Apr 22; 50(7): 3817–3834. Published online 2022 Mar 29. doi: 10.1093/nar/gkac189

PMCID:: PMC9023286

Abstract Article PDF–4.3M

Select item 902294413.

The Hippo pathway kinases LATS1 and 2 attenuate cellular responses to heavy metals through phosphorylating MTF1

Han Han, Hiroki J Nakaoka, Line Hofmann, Jeff Jiajing Zhou, Clinton Yu, Lisha Zeng, Junyu Nan, Gayoung Seo, Rebecca Elizabeth Vargas, Bing Yang, Ruxi Qi, Lee Bardwell, Dmitry A. Fishman, Ken W.Y. Cho, Lan Huang, Ray Luo, Rahul Warrior, Wenqi Wang

Nat Cell Biol. Author manuscript; available in PMC 2022 Jul 13.

Published in final edited form as: Nat Cell Biol. 2022 Jan; 24(1): 74–87. Published online 2022 Jan 13. doi: 10.1038/s41556-021-00813-8

PMCID:: PMC9022944

Abstract Article PDF–8.9M

Select item 889235614.

HTLV-1 activates YAP via NF-κB/p65 to promote oncogenesis

Tiejun Zhao, Zhilong Wang, Jinyong Fang, Wenzhao Cheng, Yiling Zhang, Jinhua Huang, Lingling Xu, Hongwei Gou, Linghui Zeng, Zhigang Jin, Masao Matsuoka

Proc Natl Acad Sci U S A. 2022 Mar 1; 119(9): e2115316119. Published online 2022 Feb 24. doi: 10.1073/pnas.2115316119

PMCID:: PMC8892356

Abstract Article PDF–1.4M

Select item 887327515.

The E3 ubiquitin ligase, FBXW5, promotes the migration and invasion of gastric cancer through the dysregulation of the Hippo pathway

Yangyang Yao, Zhen Liu, Shanshan Huang, Chunye Huang, Yuan Cao, Li Li, Hui Guo, Fenfen Liu, Shipeng Huang, Quan Liao, Xin He, Jun Chen, Junhe Li, Xiaojun Xiang, Jianping Xiong, Jun Deng

Cell Death Discov. 2022; 8: 79. Published online 2022 Feb 24. doi: 10.1038/s41420-022-00868-y

PMCID:: PMC8873275

Abstract Article PDF–4.6M

Select item 880695716.

Long non-coding RNA LOC107985656 represses the proliferation of hepatocellular carcinoma cells through activation of the tumor-suppressive Hippo pathway

Yu Zeng, Qin Xu, Nan Xu

Bioengineered. 2021; 12(1): 7964–7974. Published online 2021 Oct 8. doi: 10.1080/21655979.2021.1984005

PMCID:: PMC8806957

Abstract Article PDF–1.8M

Select item 876907217.

Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome

Caroline Benz, Muhammad Ali, Izabella Krystkowiak, Leandro Simonetti, Ahmed Sayadi, Filip Mihalic, Johanna Kliche, Eva Andersson, Per Jemth, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2022 Jan; 18(1): e10584. Published online 2022 Jan 19. doi: 10.15252/msb.202110584

PMCID:: PMC8769072

Abstract Article PDF–2.9M

Select item 872560118.

Hippo signalling maintains ER expression and ER⁺ breast cancer growth

Shenghong Ma, Zhengming Wu, Feng Yang, Jianmin Zhang, Randy L. Johnson, Michael G. Rosenfeld, Kun-Liang Guan

Nature. Author manuscript; available in PMC 2022 Jan 4.

Published in final edited form as: Nature. 2021 Mar; 591(7848): E1–E10. Published online 2021 Mar 3. doi: 10.1038/s41586-020-03131-5

PMCID:: PMC8725601

Article PDF–1.6M

Select item 861614719.

RASSF1A-Mediated Suppression of Estrogen Receptor Alpha (ERα)-Driven Breast Cancer Cell Growth Depends on the Hippo-Kinases LATS1 and 2

Sven Roßwag, Jonathan P. Sleeman, Sonja Thaler

Cells. 2021 Nov; 10(11): 2868. Published online 2021 Oct 24. doi: 10.3390/cells10112868

PMCID:: PMC8616147

Abstract Article PDF–2.6M

Select item 851385320.

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation

Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari

PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412

PMCID:: PMC8513853

Abstract Article PDF–4.1M

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