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Select item 114766471.

Nrf2/Keap1/ARE regulation by plant secondary metabolites: a new horizon in brain tumor management

Saikat Dewanjee, Hiranmoy Bhattacharya, Chiranjib Bhattacharyya, Pratik Chakraborty, Joshua Fleishman, Athanasios Alexiou, Marios Papadakis, Saurabh Kumar Jha

Cell Commun Signal. 2024; 22: 497. Published online 2024 Oct 15. doi: 10.1186/s12964-024-01878-2

PMCID:: PMC11476647

Abstract Article PDF–3.3M

Select item 110405052.

Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy

Madison A. Ward, Janakiram R. Vangala, Hatem Elif Kamber Kaya, Holly A. Byers, Nayyerehalsadat Hosseini, Antonio Diaz, Ana Maria Cuervo, Susmita Kaushik, Senthil K. Radhakrishnan

J Cell Biol. 2024 Jun 3; 223(6): e202306150. Published online 2024 Apr 24. doi: 10.1083/jcb.202306150

PMCID:: PMC11040505

Abstract Article PDF–6.2M

Select item 108102703.

Molecular mechanism of specific DNA sequence recognition by NRF1

Ke Liu, Weifang Li, Yuqing Xiao, Ming Lei, Ming Zhang, Jinrong Min

Nucleic Acids Res. 2024 Jan 25; 52(2): 953–966. Published online 2023 Dec 6. doi: 10.1093/nar/gkad1162

PMCID:: PMC10810270

Abstract Article PDF–2.0M

Select item 107711014.

NRF1 promotes primordial germ cell development, proliferation and survival

Pengxiang Wang, Jun Su, Junpeng Wang, Yilin Xie, Wei Chen, Jinhai Zhong, Yuan Wang

Cell Prolif. 2024 Jan; 57(1): e13533. Published online 2023 Aug 4. doi: 10.1111/cpr.13533

PMCID:: PMC10771101

Abstract Article PDF–12M

Select item 107113505.

NRF1 knockdown alleviates lipopolysaccharide-induced pulmonary inflammatory injury by upregulating DKK3 and inhibiting the GSK-3β/β-catenin pathway

Le Kang, Xinhua Wang, Jianfang Wang, Jing Guo, Wang Zhang, Ruirui Lei

Clin Exp Immunol. 2023 Oct; 214(1): 120–129. Published online 2023 Jul 4. doi: 10.1093/cei/uxad071

PMCID:: PMC10711350

Abstract Article PDF–5.8M

Select item 106812266.

Nrf1 is not a direct target gene of SREBP1, albeit both are integrated into the rapamycin-responsive regulatory network in human hepatoma cells

Keli Liu, Shaofan Hu, Lu Qiu, Meng Wang, Zhengwen Zhang, Guiyin Sun, Yiguo Zhang

PLoS One. 2023; 18(11): e0294508. Published online 2023 Nov 27. doi: 10.1371/journal.pone.0294508

PMCID:: PMC10681226

Abstract Article PDF–3.7M

Select item 105947277.

Nuclear respiratory factor 1 drives hepatocellular carcinoma progression by activating LPCAT1-ERK1/2-CREB axis

Ran Liu, Chuanzheng Yin, Peng Zhao, Bing Guo, Wenbo Ke, Xichuan Zheng, Dawei Xie, Yaofeng Wang, Gengqiao Wang, Yinzhao Jia, Yang Gao, Wenjun Hu, Gang Logan Liu, Zifang Song

Biol Direct. 2023; 18: 67. Published online 2023 Oct 24. doi: 10.1186/s13062-023-00428-z

PMCID:: PMC10594727

Abstract Article PDF–15M

Select item 105169268.

Evaluation of the NRF1-proteasome axis as a therapeutic target in breast cancer

Holly A. Byers, Amy N. Brooks, Janakiram R. Vangala, Jacqueline M. Grible, Alex Feygin, Charles V. Clevenger, J. Chuck Harrell, Senthil K. Radhakrishnan

Sci Rep. 2023; 13: 15843. Published online 2023 Sep 22. doi: 10.1038/s41598-023-43121-x

PMCID:: PMC10516926

Abstract Article PDF–2.3M

Select item 102374229.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1004159510.

NRF1 Regulates the Epithelial Mesenchymal Transition of Breast Cancer by Modulating ROS Homeostasis

Linjuan Sun, Nan Ouyang, Shaheryar Shafi, Rongchuan Zhao, Jinlin Pan, Lei Hong, Xueyan Song, Xiaohan Sa, Yuanshuai Zhou

Technol Cancer Res Treat. 2023; 22: 15330338231161141. Published online 2023 Mar 23. doi: 10.1177/15330338231161141

PMCID:: PMC10041595

Abstract Article PDF–2.3M

Select item 969050411.

Racial Disparities in Methylation of NRF1, FTO, and LEPR Gene in Childhood Obesity

Priyadarshni Patel, Vaithinathan Selvaraju, Jeganathan Ramesh Babu, Xu Wang, Thangiah Geetha

Genes (Basel) 2022 Nov; 13(11): 2030. Published online 2022 Nov 4. doi: 10.3390/genes13112030

PMCID:: PMC9690504

Abstract Article PDF–2.1M

Select item 945412912.

Long noncoding RNA LINC01132 enhances immunosuppression and therapy resistance via NRF1/DPP4 axis in hepatocellular carcinoma

Jiwei Zhang, Tao Pan, Weiwei Zhou, Ya Zhang, Gang Xu, Qi Xu, Si Li, Yueying Gao, Zhengtao Wang, Juan Xu, Yongsheng Li

J Exp Clin Cancer Res. 2022; 41: 270. Published online 2022 Sep 8. doi: 10.1186/s13046-022-02478-z

PMCID:: PMC9454129

Abstract Article PDF–6.9M

Select item 935372013.

Nuclear Respiratory Factor 1 Overexpression Inhibits Proliferation and Migration of PC3 Prostate Cancer Cells

CHUN-HSIEN WU, PEI-FANG HSIEH, YEN-HSI LEE, WADE WEI-TING KUO, RICHARD CHEN-YU WU, YUNG-YAO LIN, CHIH-HSIN HUNG, MING-LIN HSIEH, SEE-TONG PANG, YU-LIN YANG, VICTOR C. LIN

Cancer Genomics Proteomics. 2022 Sep-Oct; 19(5): 614–623. Published online 2022 Sep 3. doi: 10.21873/cgp.20346

PMCID:: PMC9353720

Abstract Article PDF–6.4M

Select item 927928514.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 926261415.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 902744716.

Nuclear respiratory factor 1 promotes the growth of liver hepatocellular carcinoma cells via E2F1 transcriptional activation

Dan Wang, Baolan Wan, Xiaojing Zhang, Pingping Sun, Shu Lu, Chenxu Liu, Li Zhu

BMC Gastroenterol. 2022; 22: 198. Published online 2022 Apr 21. doi: 10.1186/s12876-022-02260-7

PMCID:: PMC9027447

Abstract Article PDF–6.1M

Select item 879158017.

Multiple myeloma cells depend on the DDI2/NRF1-mediated proteasome stress response for survival

Tianzeng Chen, Matthew Ho, Jenna Briere, Maria Moscvin, Peter G. Czarnecki, Kenneth C. Anderson, T. Keith Blackwell, Giada Bianchi

Blood Adv. 2022 Jan 25; 6(2): 429–440. Published online 2022 Jan 17. doi: 10.1182/bloodadvances.2020003820

PMCID:: PMC8791580

Abstract Article PDF–1.7M

Select item 860478418.

NRF1 Association with AUTS2-Polycomb Mediates Specific Gene Activation in the Brain

Sanxiong Liu, Kimberly A. Aldinger, Chi Vicky Cheng, Takae Kiyama, Mitali Dave, Hanna K. McNamara, Wukui Zhao, James M. Stafford, Nicolas Descostes, Pedro Lee, Stefano G. Caraffi, Ivan Ivanovski, Edoardo Errichiello, Christiane Zweier, Orsetta Zuffardi, Michael Schneider, Antigone S. Papavasiliou, M. Scott Perry, Jennifer Humberson, Megan T. Cho, Astrid Weber, Andrew Swale, Tudor C. Badea, Chai-An Mao, Livia Garavelli, William B. Dobyns, Danny Reinberg

Mol Cell. Author manuscript; available in PMC 2022 Nov 18.

Published in final edited form as: Mol Cell. 2021 Nov 18; 81(22): 4663–4676.e8. Published online 2021 Oct 11. doi: 10.1016/j.molcel.2021.09.020

Correction in:: Mol Cell. 2021 Nov 18; 81(22): 4757.

PMCID:: PMC8604784

Abstract Article PDF–2.8M

Select item 835296419.

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 819851820.

Nuclear Respiratory Factor-1, a Novel SMAD4 Binding Protein, Represses TGF-β/SMAD4 Signaling by Functioning as a Transcriptional Cofactor

Nirmal Rajasekaran, Kyoung Song, Jin-Hee Lee, Yun Wei, Özgür Cem Erkin, Hunseok Lee, Young-Kee Shin

Int J Mol Sci. 2021 Jun; 22(11): 5595. Published online 2021 May 25. doi: 10.3390/ijms22115595

PMCID:: PMC8198518

Abstract Article PDF–20M

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