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Select item 101645911.

RNA binding proteins Smaug and Cup induce CCR4–NOT-dependent deadenylation of the nanos mRNA in a reconstituted system

Filip Pekovic, Christiane Rammelt, Jana Kubíková, Jutta Metz, Mandy Jeske, Elmar Wahle

Nucleic Acids Res. 2023 May 8; 51(8): 3950–3970. Published online 2023 Mar 23. doi: 10.1093/nar/gkad159

PMCID:: PMC10164591

Article PDF–4.6M

Select item 87749922.

Rapid Cis–Trans Coevolution Driven by a Novel Gene Retroposed from a Eukaryotic Conserved CCR4–NOT Component in Drosophila

Benjamin H. Krinsky, Robert K. Arthur, Shengqian Xia, Dylan Sosa, Deanna Arsala, Kevin P. White, Manyuan Long

Genes (Basel) 2022 Jan; 13(1): 57. Published online 2021 Dec 26. doi: 10.3390/genes13010057

PMCID:: PMC8774992

Article PDF–1.8M

Select item 87631313.

Rapid Gene Evolution in an Ancient Post-transcriptional and Translational Regulatory System Compensates for Meiotic X Chromosomal Inactivation

Shengqian Xia, Iuri M Ventura, Andreas Blaha, Annamaria Sgromo, Shuaibo Han, Elisa Izaurralde, Manyuan Long

Mol Biol Evol. 2022 Jan; 39(1): msab296. Published online 2021 Oct 9. doi: 10.1093/molbev/msab296

PMCID:: PMC8763131

Article PDF–846K

Select item 86698344.

Tumor–host interactions through the lens of Drosophila

David Bilder, Katy Ong, Tsai-Ching Hsi, Kavya Adiga, Jung Kim

Nat Rev Cancer. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Nat Rev Cancer. 2021 Nov; 21(11): 687–700. Published online 2021 Aug 13. doi: 10.1038/s41568-021-00387-5

PMCID:: PMC8669834

Article PDF–385K

Select item 86644865.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Article PDF–3.1M

Select item 86214066.

On the Origin and Evolution of Drosophila New Genes during Spermatogenesis

Qianwei Su, Huangyi He, Qi Zhou

Genes (Basel) 2021 Nov; 12(11): 1796. Published online 2021 Nov 15. doi: 10.3390/genes12111796

PMCID:: PMC8621406

Article PDF–2.5M

Select item 69615787.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Article PDF–3.6M

Select item 63628128.

A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4–NOT complex

Csilla Keskeny, Tobias Raisch, Annamaria Sgromo, Cátia Igreja, Dipankar Bhandari, Oliver Weichenrieder, Elisa Izaurralde

Genes Dev. 2019 Feb 1; 33(3-4): 236–252. doi: 10.1101/gad.320952.118

PMCID:: PMC6362812

Article PDF–2.5M

Select item 58243579.

Drosophila Bag-of-marbles directly interacts with the CAF40 subunit of the CCR4–NOT complex to elicit repression of mRNA targets

Annamaria Sgromo, Tobias Raisch, Charlotte Backhaus, Csilla Keskeny, Vikram Alva, Oliver Weichenrieder, Elisa Izaurralde

RNA. 2018 Mar; 24(3): 381–395. doi: 10.1261/rna.064584.117

PMCID:: PMC5824357

Article PDF–16M

Select item 570780510.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Article PDF–3.2M

Select item 568900211.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Article PDF–4.0M

Select item 530382912.

A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin

Annamaria Sgromo, Tobias Raisch, Praveen Bawankar, Dipankar Bhandari, Ying Chen, Duygu Kuzuoğlu-Öztürk, Oliver Weichenrieder, Elisa Izaurralde

Nat Commun. 2017; 8: 14307. Published online 2017 Feb 6. doi: 10.1038/ncomms14307

PMCID:: PMC5303829

Article PDF–3.7M

Select item 478811613.

Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet

Ibrahim Ömer Çiçek, Samir Karaca, Marko Brankatschk, Suzanne Eaton, Henning Urlaub, Halyna R. Shcherbata

Genetics. 2016 Mar; 202(3): 1167–1183. Published online 2016 Jan 22. doi: 10.1534/genetics.115.185371

PMCID:: PMC4788116

Article PDF–4.7M

Select item 473800514.

Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes

Sadhna Phanse, Cuihong Wan, Blake Borgeson, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Bezginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, W. Brent Derry, Elisabeth R. Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Data Brief. 2016 Mar; 6: 715–721. Published online 2015 Dec 12. doi: 10.1016/j.dib.2015.11.062

PMCID:: PMC4738005

Article PDF–205K

Select item 452833015.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Article PDF–2.2M

Select item 452832916.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Article PDF–4.9M

Select item 436843417.

Multi-Functional Regulation of 4E-BP Gene Expression by the Ccr4-Not Complex

Hirokazu Okada, Ralf B. Schittenhelm, Anna Straessle, Ernst Hafen

PLoS One. 2015; 10(3): e0113902. Published online 2015 Mar 20. doi: 10.1371/journal.pone.0113902

PMCID:: PMC4368434

Article PDF–2.1M

Select item 435288718.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114

PMCID:: PMC4352887

Article PDF–1022K

Select item 407996719.

Evolution of H3K27me3-marked chromatin is linked to gene expression evolution and to patterns of gene duplication and diversification

Robert K. Arthur, Lijia Ma, Matthew Slattery, Rebecca F. Spokony, Alexander Ostapenko, Nicolas Nègre, Kevin P. White

Genome Res. 2014 Jul; 24(7): 1115–1124. doi: 10.1101/gr.162008.113

PMCID:: PMC4079967

Article PDF–1.2M

Select item 403331820.

Deadenylation of mRNA by the CCR4–NOT complex in Drosophila: molecular and developmental aspects

Claudia Temme, Martine Simonelig, Elmar Wahle

Front Genet. 2014; 5: 143. Prepublished online 2014 Mar 30. Published online 2014 May 26. doi: 10.3389/fgene.2014.00143

PMCID:: PMC4033318

Article PDF–946K

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