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Select item 114944521.

Pde3a and Pde3b regulation of murine pulmonary artery smooth muscle cell growth and metabolism

Paulina N. Krause, Gabrielle McGeorge, Jennifer L. McPeek, Sidra Khalid, Leif D. Nelin, Yusen Liu, Bernadette Chen

Physiol Rep. 2024 Oct; 12(20): e70089. Published online 2024 Oct 22. doi: 10.14814/phy2.70089

PMCID:: PMC11494452

Abstract Article PDF–5.7M

Select item 114156002.

PRDM16 determines specification of ventricular cardiomyocytes by suppressing alternative cell fates

Jore Van Wauwe, Alexia Mahy, Sander Craps, Samaneh Ekhteraei-Tousi, Pieter Vrancaert, Hannelore Kemps, Wouter Dheedene, Rosa Doñate Puertas, Sander Trenson, H. Llewelyn Roderick, Manu Beerens, Aernout Luttun

Life Sci Alliance. 2024 Dec; 7(12): e202402719. Published online 2024 Sep 20. doi: 10.26508/lsa.202402719

PMCID:: PMC11415600

Abstract Article PDF–5.1M

Select item 85900743.

Rise of cGMP by partial phosphodiesterase-3A degradation enhances cardioprotection during hypoxia

Nadja I. Bork, Anna Kuret, Melanie Cruz Santos, Cristina E. Molina, Beate Reiter, Hermann Reichenspurner, Andreas Friebe, Boris V. Skryabin, Timofey S. Rozhdestvensky, Michaela Kuhn, Robert Lukowski, Viacheslav O. Nikolaev

Redox Biol. 2021 Dec; 48: 102179. Published online 2021 Nov 6. doi: 10.1016/j.redox.2021.102179

PMCID:: PMC8590074

Abstract Article PDF–6.7M

Select item 83926064.

Inhibition of Phosphodiesterase 3A by Cilostazol Dampens Proinflammatory Platelet Functions

Daniëlle M. Coenen, Alexandra C. A. Heinzmann, Silvia Oggero, Hugo J. Albers, Magdolna Nagy, Perrine Hagué, Marijke J. E. Kuijpers, Jean-Marie Vanderwinden, Andries D. van der Meer, Mauro Perretti, Rory R. Koenen, Judith M. E. M. Cosemans

Cells. 2021 Aug; 10(8): 1998. Published online 2021 Aug 5. doi: 10.3390/cells10081998

PMCID:: PMC8392606

Abstract Article PDF–2.7M

Select item 83427975.

Nitration of protein kinase G-Iα modulates cyclic nucleotide crosstalk via phosphodiesterase 3A: Implications for acute lung injury

Evgeny A. Zemskov, Xiaomin Wu, Saurabh Aggarwal, Mannivannan Yegambaram, Christine Gross, Qing Lu, Hui Wang, Haiyang Tang, Ting Wang, Stephen M. Black

J Biol Chem. 2021 Aug; 297(2): 100946. Published online 2021 Jul 10. doi: 10.1016/j.jbc.2021.100946

PMCID:: PMC8342797

Abstract Article PDF–1.8M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 68424277.

Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling

Krishnakali Dasgupta, Jong Uk Chung, Kesava Asam, Juhee Jeong

Dev Biol. Author manuscript; available in PMC 2020 Nov 15.

Published in final edited form as: Dev Biol. 2019 Nov 15; 455(2): 434–448. Published online 2019 Jul 24. doi: 10.1016/j.ydbio.2019.07.015

PMCID:: PMC6842427

Abstract Article PDF–6.1M

Select item 63108348.

Steroidogenic differentiation and PKA signaling are programmed by histone methyltransferase EZH2 in the adrenal cortex

Mickael Mathieu, Coralie Drelon, Stéphanie Rodriguez, Houda Tabbal, Amandine Septier, Christelle Damon-Soubeyrand, Typhanie Dumontet, Annabel Berthon, Isabelle Sahut-Barnola, Cyril Djari, Marie Batisse-Lignier, Jean-Christophe Pointud, Damien Richard, Gwenneg Kerdivel, Marie-Ange Calméjane, Valentina Boeva, Igor Tauveron, Anne-Marie Lefrançois-Martinez, Antoine Martinez, Pierre Val

Proc Natl Acad Sci U S A. 2018 Dec 26; 115(52): E12265–E12274. Published online 2018 Dec 12. doi: 10.1073/pnas.1809185115

PMCID:: PMC6310834

Abstract Article PDF–2.4M

Select item 58211789.

A pathophysiological role of PDE3 in allergic airway inflammation

Jan Beute, Melanie Lukkes, Ewout P. Koekoek, Hedwika Nastiti, Keerthana Ganesh, Marjolein J.W. de Bruijn, Steve Hockman, Menno van Nimwegen, Gert-Jan Braunstahl, Louis Boon, Bart N. Lambrecht, Vince C. Manganiello, Rudi W. Hendriks, Alex KleinJan

JCI Insight. 2018 Jan 25; 3(2): e94888. Published online 2018 Jan 25. doi: 10.1172/jci.insight.94888

PMCID:: PMC5821178

Abstract Article PDF–5.7M

Select item 552228710.

Phosphodiesterase 3A: a new player in development of interstitial cells of Cajal and a prospective target in gastrointestinal stromal tumors (GIST)

Pierre Vandenberghe, Perrine Hagué, Steven C. Hockman, Vincent C. Manganiello, Pieter Demetter, Christophe Erneux, Jean-Marie Vanderwinden

Oncotarget. 2017 Jun 20; 8(25): 41026–41043. Published online 2017 Apr 10. doi: 10.18632/oncotarget.17010

PMCID:: PMC5522287

Abstract Article PDF–17M

Select item 443496411.

Multiple Pathways Mediate Luteinizing Hormone Regulation of cGMP Signaling in the Mouse Ovarian Follicle

Xueqing Liu, Fang Xie, Alberuni Musa Zamah, Binyun Cao, Marco Conti

Biol Reprod. 2014 Jul; 91(1): 9. Published online 2014 Apr 16. doi: 10.1095/biolreprod.113.116814

Correction in:: Biol Reprod. 2014 Sep 1; 91(3): 72, 1-1.

PMCID:: PMC4434964

Abstract Article PDF–725K

Select item 441888612.

Targeted disruption of PDE3B, but not PDE3A, protects murine heart from ischemia/reperfusion injury

Youn Wook Chung, Claudia Lagranha, Yong Chen, Junhui Sun, Guang Tong, Steven C. Hockman, Faiyaz Ahmad, Shervin G. Esfahani, Dahae H. Bae, Nazari Polidovitch, Jian Wu, Dong Keun Rhee, Beom Seob Lee, Marjan Gucek, Mathew P. Daniels, Christine A. Brantner, Peter H. Backx, Elizabeth Murphy, Vincent C. Manganiello

Proc Natl Acad Sci U S A. 2015 Apr 28; 112(17): E2253–E2262. Published online 2015 Apr 15. doi: 10.1073/pnas.1416230112

PMCID:: PMC4418886

Abstract Article PDF–1.3M

Select item 391316513.

Phosphoinositide 3-Kinase γ Protects Against Catecholamine-Induced Ventricular Arrhythmia Through Protein Kinase A–Mediated Regulation of Distinct Phosphodiesterases

Alessandra Ghigo, Alessia Perino, Hind Mehel, Alexandra Zahradníková, Jr, Fulvio Morello, Jérôme Leroy, Viacheslav O. Nikolaev, Federico Damilano, James Cimino, Elisa De Luca, Wito Richter, Ruth Westenbroek, William A. Catterall, Jin Zhang, Chen Yan, Marco Conti, Ana Maria Gomez, Grégoire Vandecasteele, Emilio Hirsch, Rodolphe Fischmeister

Circulation. Author manuscript; available in PMC 2014 Feb 4.

Published in final edited form as: Circulation. 2012 Oct 23; 126(17): 2073–2083. Published online 2012 Sep 24. doi: 10.1161/CIRCULATIONAHA.112.114074

PMCID:: PMC3913165

Abstract Article PDF–617K

Select item 386957014.

Cyclic Nucleotide Phosphodiesterase 3A1 Protects the Heart Against Ischemia-Reperfusion Injury

Masayoshi Oikawa, Meiping Wu, Soyeon Lim, Walter E. Knight, Clint L. Miller, Yujun Cai, Yan Lu, Burns C. Blaxall, Yasuchika Takeishi, Jun-ichi Abe, Chen Yan

J Mol Cell Cardiol. Author manuscript; available in PMC 2014 Nov 1.

Published in final edited form as: J Mol Cell Cardiol. 2013 Nov; 64: 10.1016/j.yjmcc.2013.08.003. Published online 2013 Aug 27. doi: 10.1016/j.yjmcc.2013.08.003

PMCID:: PMC3869570

Abstract Article PDF–897K

Select item 381794615.

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates

Jeremy A. Miller, Jason Nathanson, Daniel Franjic, Sungbo Shim, Rachel A. Dalley, Sheila Shapouri, Kimberly A. Smith, Susan M. Sunkin, Amy Bernard, Jeffrey L. Bennett, Chang-Kyu Lee, Michael J. Hawrylycz, Allan R. Jones, David G. Amaral, Nenad Sestan, Fred H. Gage, Ed S. Lein

Development. 2013 Nov 15; 140(22): 4633–4644. doi: 10.1242/dev.097212

PMCID:: PMC3817946

Abstract Article

Select item 371879116.

A Tudor Domain Protein SPINDLIN1 Interacts with the mRNA-Binding Protein SERBP1 and Is Involved in Mouse Oocyte Meiotic Resumption

Ting Gang Chew, Anne Peaston, Ai Khim Lim, Chanchao Lorthongpanich, Barbara B. Knowles, Davor Solter

PLoS One. 2013; 8(7): e69764. Published online 2013 Jul 22. doi: 10.1371/journal.pone.0069764

PMCID:: PMC3718791

Abstract Article PDF–9.0M

Select item 357962117.

PDE3A Regulates Basal Myocardial Contractility through Interacting with SERCA2a-Signaling Complexes in Mouse Heart

Sanja Beca, Faiyaz Ahmad, Weixing Shen, Jie Liu, Samy Makary, Nazari Polidovitch, Junhui Sun, Steven Hockman, Youn Wook Chung, Matthew Movesian, Elizabeth Murphy, Vincent Manganiello, Peter H. Backx

Circ Res. Author manuscript; available in PMC 2014 Jan 18.

Published in final edited form as: Circ Res. 2013 Jan 18; 112(2): 289–297. Published online 2012 Nov 19. doi: 10.1161/CIRCRESAHA.111.300003

Correction in:: Circ Res. 2018 Oct 26; 123(10): e33.

PMCID:: PMC3579621

Abstract Article PDF–2.2M

Select item 357241018.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 344157419.

FSH Modulates PKAI and GPR3 Activities in Mouse Oocyte of COC in a Gap Junctional Communication (GJC)-Dependent Manner to Initiate Meiotic Resumption

Junxia Li, Guankun Mao, Guoliang Xia

PLoS One. 2012; 7(9): e37835. Published online 2012 Sep 13. doi: 10.1371/journal.pone.0037835

PMCID:: PMC3441574

Abstract Article PDF–3.5M

Select item 322559520.

Role of PDE3A in Regulation of Cell Cycle Progression in Mouse Vascular Smooth Muscle Cells and Oocytes: Implications in Cardiovascular Diseases and Infertility

Najma Begum, Weixing Shen, Vincent Manganiello

Curr Opin Pharmacol. Author manuscript; available in PMC 2012 Dec 1.

Published in final edited form as: Curr Opin Pharmacol. 2011 Dec; 11(6): 725–729. Published online 2011 Nov 1. doi: 10.1016/j.coph.2011.10.006

PMCID:: PMC3225595

Abstract Article PDF–487K

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