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Select item 113183141.

Inhibition of transcription factor NFAT activity in activated platelets enhances their aggregation and exacerbates gram-negative bacterial septicemia

Valentina Poli, Marco Di Gioia, Martha Sola-Visner, Francesca Granucci, Andrew L. Frelinger, III, Alan D. Michelson, Ivan Zanoni

Immunity. Author manuscript; available in PMC 2024 Aug 12.

Published in final edited form as: Immunity. 2022 Feb 8; 55(2): 224–236.e5. Published online 2022 Jan 6. doi: 10.1016/j.immuni.2021.12.002

PMCID:: PMC11318314

Abstract Article PDF–2.2M

Select item 110287962.

NFAT1 transcription factor is central in the regulation of tissue microenvironment for tumor metastasis

Miriam B. F. Werneck, Adriana Vieira-de-Abreu, Roger Chammas, João P. B. Viola

Cancer Immunol Immunother. 2011 Apr; 60(4): 537–546. Published online 2011 Jan 12. doi: 10.1007/s00262-010-0964-4

PMCID:: PMC11028796

Abstract Article PDF–692K

Select item 106171973.

NFAT1 and NFκB regulates expression of the common γ-chain cytokine receptor in activated T cells

Ju A Shim, So Min Lee, Jin Woo Jeong, Hyori Kim, Woo Jae Son, Jun Hong Park, Parkyong Song, Sin-Hyeog Im, Sangsu Bae, Jung-Hyun Park, Yuna Jo, Changwan Hong

Cell Commun Signal. 2023; 21: 309. Published online 2023 Oct 30. doi: 10.1186/s12964-023-01326-7

PMCID:: PMC10617197

Abstract Article PDF–5.1M

Select item 105426154.

WNT16b promotes the proliferation and self‐renewal of human limbal epithelial stem/progenitor cells via activating the calcium/calcineurin A/NFATC2 pathway

Xichen Wan, Songjiao Zhao, Yiqin Dai, Jing Zhang, Yan Shen, Lan Gong, Qihua Le

Cell Prolif. 2023 Oct; 56(10): e13460. Published online 2023 Mar 27. doi: 10.1111/cpr.13460

PMCID:: PMC10542615

Abstract Article PDF–8.5M

Select item 97198405.

Macrophage P2Y₆ Receptor Signaling Selectively Activates NFATC2 and Suppresses Allergic Lung Inflammation

Jun Nagai, Junrui Lin, Joshua A. Boyce

J Immunol. 2022 Dec 15; 209(12): 2293–2303. Published online 2022 Dec 15. doi: 10.4049/jimmunol.2200452

PMCID:: PMC9719840

Abstract Article PDF–2.2M

Select item 97047546.

Dapl1 controls NFATc2 activation to regulate CD8⁺ T cell exhaustion and responses in chronic infection and cancer

Lele Zhu, Xiaofei Zhou, Meidi Gu, Jiseong Kim, Yanchuan Li, Chun-Jung Ko, Xiaoping Xie, Tianxiao Gao, Xuhong Cheng, Shao-Cong Sun

Nat Cell Biol. Author manuscript; available in PMC 2022 Nov 28.

Published in final edited form as: Nat Cell Biol. 2022 Jul; 24(7): 1165–1176. Published online 2022 Jun 30. doi: 10.1038/s41556-022-00942-8

PMCID:: PMC9704754

Abstract Article PDF–3.1M

Select item 95865677.

Genetic inhibition of nuclear factor of activated T-cell c2 prevents atrial fibrillation in CREM transgenic mice

Li Ni, Satadru K Lahiri, Jiali Nie, Xiaolu Pan, Issam Abu-Taha, Julia O Reynolds, Hannah M Campbell, Haihao Wang, Markus Kamler, Wilhelm Schmitz, Frank Ulrich Müller, Na Li, Xiang Wei, Dao Wen Wang, Dobromir Dobrev, Xander H T Wehrens

Cardiovasc Res. 2022 Sep; 118(13): 2805–2818. Published online 2021 Oct 14. doi: 10.1093/cvr/cvab325

PMCID:: PMC9586567

Abstract Article PDF–1.6M

Select item 85535698.

Identification of direct transcriptional targets of NFATC2 that promote β cell proliferation

Shane P. Simonett, Sunyoung Shin, Jacob A. Herring, Rhonda Bacher, Linsin A. Smith, Chenyang Dong, Mary E. Rabaglia, Donnie S. Stapleton, Kathryn L. Schueler, Jeea Choi, Matthew N. Bernstein, Daniel R. Turkewitz, Carlos Perez-Cervantes, Jason Spaeth, Roland Stein, Jeffery S. Tessem, Christina Kendziorski, Sündüz Keleş, Ivan P. Moskowitz, Mark P. Keller, Alan D. Attie

J Clin Invest. 2021 Nov 1; 131(21): e144833. Published online 2021 Nov 1. doi: 10.1172/JCI144833

PMCID:: PMC8553569

Abstract Article PDF–2.7M

Select item 83354009.

Rapid and Efficient Gene Editing for Direct Transplantation of Naive Murine Cas9⁺ T Cells

Snigdha Majumder, Isabelle Jugovic, Domenica Saul, Luisa Bell, Nadine Hundhausen, Rishav Seal, Andreas Beilhack, Andreas Rosenwald, Dimitrios Mougiakakos, Friederike Berberich-Siebelt

Front Immunol. 2021; 12: 683631. Published online 2021 Jul 21. doi: 10.3389/fimmu.2021.683631

PMCID:: PMC8335400

Abstract Article PDF–7.1M

Select item 831323910.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 826328511.

NFAT transcription factors are essential and redundant actors for leukemia initiating potential in T-cell acute lymphoblastic leukemia

Claire Catherinet, Diana Passaro, Stéphanie Gachet, Hind Medyouf, Anne Reynaud, Charlène Lasgi, Jacques Ghysdael, Christine Tran Quang

PLoS One. 2021; 16(7): e0254184. Published online 2021 Jul 7. doi: 10.1371/journal.pone.0254184

PMCID:: PMC8263285

Abstract Article PDF–2.4M

Select item 810099112.

LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies

Changyoun Kim, Alexandria Beilina, Nathan Smith, Yan Li, Minhyung Kim, Ravindran Kumaran, Alice Kaganovich, Adamantios Mamais, Anthony Adame, Michiyo Iba, Somin Kwon, Won-Jae Lee, Soo-Jean Shin, Robert Rissman, Sungyong You, Seung-Jae Lee, Andrew B. Singleton, Mark R. Cookson, Eliezer Masliah

Sci Transl Med. Author manuscript; available in PMC 2021 May 6.

Published in final edited form as: Sci Transl Med. 2020 Oct 14; 12(565): eaay0399. doi: 10.1126/scitranslmed.aay0399

PMCID:: PMC8100991

Abstract Article PDF–3.7M

Select item 789460513.

Nitric oxide attenuates microglia proliferation by sequentially facilitating calcium influx through TRPV2 channels, activating NFATC2, and increasing p21 transcription

Matthew J.E. Maksoud, Vasiliki Tellios, Wei-Yang Lu

Cell Cycle. 2021; 20(4): 417–433. Published online 2021 Feb 2. doi: 10.1080/15384101.2021.1877936

PMCID:: PMC7894605

Abstract Article PDF–11M

Select item 757626214.

Testicular Lmcd1 regulates phagocytosis by Sertoli cells through modulation of NFAT1/Txlna signaling pathway

Xiaohang Jin, Sheng Zhang, Tianbing Ding, Pengtao Zhao, Chunli Zhang, Yuxing Zhang, Wei Li

Aging Cell. 2020 Oct; 19(10): e13217. Published online 2020 Aug 9. doi: 10.1111/acel.13217

PMCID:: PMC7576262

Abstract Article PDF–1.6M

Select item 754453215.

Functional modulation of atrio-ventricular conduction by enhanced late sodium current and calcium-dependent mechanisms in Scn5a^1798insD/+ mice

Mathilde R Rivaud, Gerard A Marchal, Rianne Wolswinkel, John A Jansen, Ingeborg van der Made, Leander Beekman, Adrián Ruiz-Villalba, Antonius Baartscheer, Sridharan Rajamani, Luiz Belardinelli, Toon A B van Veen, Cristina Basso, Gaetano Thiene, Esther E Creemers, Connie R Bezzina, Carol Ann Remme

Europace. 2020 Oct; 22(10): 1579–1589. Published online 2020 Aug 10. doi: 10.1093/europace/euaa127

PMCID:: PMC7544532

Abstract Article PDF–1.4M

Select item 750985516.

Genetic inhibition of NFATC2 attenuates asparaginase hypersensitivity in mice

Sanjay Rathod, Manda Ramsey, Fred D. Finkelman, Christian A. Fernandez

Blood Adv. 2020 Sep 22; 4(18): 4406–4416. Published online 2020 Sep 15. doi: 10.1182/bloodadvances.2020002478

PMCID:: PMC7509855

Abstract Article PDF–1.5M

Select item 741599117.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 685906618.

Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics

Guillaume Voisinne, Kristof Kersse, Karima Chaoui, Liaoxun Lu, Julie Chaix, Lichen Zhang, Marisa Goncalves Menoita, Laura Girard, Youcef Ounoughene, Hui Wang, Odile Burlet-Schiltz, Hervé Luche, Frédéric Fiore, Marie Malissen, Anne Gonzalez de Peredo, Yinming Liang, Romain Roncagalli, Bernard Malissen

Nat Immunol. Author manuscript; available in PMC 2020 Apr 7.

Published in final edited form as: Nat Immunol. 2019 Nov 1; 20(11): 1530–1541. Published online 2019 Oct 7. doi: 10.1038/s41590-019-0489-8

PMCID:: PMC6859066

Abstract Article PDF–2.9M

Select item 685601519.

The Calmodulin Binding Region of the Synaptic Vesicle Protein Mover Is Required for Homomeric Interaction and Presynaptic Targeting

Asha Kiran Akula, Xin Zhang, Julio S. Viotti, Dennis Nestvogel, Jeong-Seop Rhee, Rene Ebrecht, Kerstin Reim, Fred Wouters, Thomas Liepold, Olaf Jahn, Ivan Bogeski, Thomas Dresbach

Front Mol Neurosci. 2019; 12: 249. Published online 2019 Nov 8. doi: 10.3389/fnmol.2019.00249

PMCID:: PMC6856015

Abstract Article PDF–6.1M

Select item 674295320.

NFAT1 Regulates Ly6C^hi Monocyte Recruitment to the CNS and Plays an Essential Role in Resistance to Toxoplasma gondii Infection

Luciana Benevides, Verônica M. Saltarelli, Franciele Pioto, Laís A. Sacramento, Murilo S. Dias, Gretel R. Rodríguez, João P. B. Viola, Vanessa Carregaro, João S. Silva

Front Immunol. 2019; 10: 2105. Published online 2019 Sep 6. doi: 10.3389/fimmu.2019.02105

PMCID:: PMC6742953

Abstract Article PDF–1.9M

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