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Select item 112643311.

Circadian-clock-controlled endocrine and cytokine signals regulate multipotential innate lymphoid cell progenitors in the bone marrow

Qingyang Liu, Shams Tabrez, Patrick Niekamp, Chang H. Kim

Cell Rep. Author manuscript; available in PMC 2024 Jul 23.

Published in final edited form as: Cell Rep. 2024 May 28; 43(5): 114200. Published online 2024 May 7. doi: 10.1016/j.celrep.2024.114200

PMCID:: PMC11264331

Abstract Article PDF–2.9M

Select item 112524412.

Antibody Fc-receptor FcεR1γ stabilizes cell surface receptors in group 3 innate lymphoid cells and promotes anti-infection immunity

Chao Huang, Wenting Zhu, Qing Li, Yuchen Lei, Xi Chen, Shaorui Liu, Dianyu Chen, Lijian Zhong, Feng Gao, Shujie Fu, Danyang He, Jinsong Li, Heping Xu

Nat Commun. 2024; 15: 5981. Published online 2024 Jul 16. doi: 10.1038/s41467-024-50266-4

PMCID:: PMC11252441

Abstract Article PDF–3.9M

Select item 112173683.

[¹⁸F]F-AraG imaging reveals association between neuroinflammation and brown- and bone marrow adipose tissue

Jelena Levi, Caroline Guglielmetti, Timothy J. Henrich, John C. Yoon, Prafulla C. Gokhale, David A. Reardon, Juliet Packiasamy, Lyna Huynh, Hilda Cabrera, Marisa Ruzevich, Joseph Blecha, Michael J. Peluso, Tony L. Huynh, Sung-Min An, Mark Dornan, Anthony P. Belanger, Quang-Dé Nguyen, Youngho Seo, Hong Song, Myriam M. Chaumeil, Henry F. VanBrocklin, Hee-Don Chae

Commun Biol. 2024; 7: 793. Published online 2024 Jul 1. doi: 10.1038/s42003-024-06494-x

PMCID:: PMC11217368

Abstract Article PDF–9.2M

Select item 111805974.

PD-1 signaling in neonates restrains CD8⁺ T cell function and protects against respiratory viral immunopathology

Taylor Eddens, Olivia B. Parks, Yu Zhang, Michelle L. Manni, Jean-Laurent Casanova, Masato Ogishi, John V. Williams

Mucosal Immunol. Author manuscript; available in PMC 2024 Jun 17.

Published in final edited form as: Mucosal Immunol. 2024 Jun; 17(3): 476–490. Published online 2024 Jan 3. doi: 10.1016/j.mucimm.2023.12.004

PMCID:: PMC11180597

Abstract Article PDF–2.1M

Select item 111496305.

FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice

Mana Momenilandi, Romain Lévy, Steicy Sobrino, Jingwei Li, Chantal Lagresle-Peyrou, Hossein Esmaeilzadeh, Antoine Fayand, Corentin Le Floc’h, Antoine Guérin, Erika Della Mina, Debra Shearer, Ottavia M. Delmonte, Ahmad Yatim, Kevin Mulder, Mathieu Mancini, Darawan Rinchai, Adeline Denis, Anna-Lena Neehus, Karla Balogh, Sarah Brendle, Hassan Rokni-Zadeh, Majid Changi-Ashtiani, Yoann Seeleuthner, Caroline Deswarte, Boris Bessot, Cassandre Cremades, Marie Materna, Axel Cederholm, Masato Ogishi, Quentin Philippot, Omer Beganovic, Mania Ackermann, Margareta Wuyts, Taushif Khan, Sébastien Fouéré, Florian Herms, Johan Chanal, Boaz Palterer, Julie Bruneau, Thierry Molina, Stéphanie Leclerc-Mercier, Jean-Luc Prétet, Leila Youssefian, Hassan Vahidnezhad, Nima Parvaneh, Kristl G. Claeys, Rik Schrijvers, Marine Luka, Philippe Pérot, Jacques Fourgeaud, Céline Nourrisson, Philippe Poirier, Emmanuelle Jouanguy, Stéphanie Boisson-Dupuis, Jacinta Bustamante, Luigi D. Notarangelo, Neil Christensen, Nils Landegren, Laurent Abel, Nico Marr, Emmanuelle Six, David Langlais, Tim Waterboer, Florent Ginhoux, Cindy S. Ma, Stuart G Tangye, Isabelle Meyts, Nico Lachmann, Jiafen Hu, Mohammad Shahrooei, Xavier Bossuyt, Jean-Laurent Casanova, Vivien Béziat

Cell. Author manuscript; available in PMC 2024 Jun 4.

Published in final edited form as: Cell. 2024 May 23; 187(11): 2817–2837.e31. Published online 2024 May 3. doi: 10.1016/j.cell.2024.04.009

PMCID:: PMC11149630

Abstract Article PDF–3.3M

Select item 111490946.

Exonic knock-out and knock-in gene editing in hematopoietic stem and progenitor cells rescues RAG1 immunodeficiency

Maria Carmina Castiello, Chiara Brandas, Samuele Ferrari, Simona Porcellini, Nicolò Sacchetti, Daniele Canarutto, Elena Draghici, Ivan Merelli, Matteo Barcella, Gabriele Pelosi, Valentina Vavassori, Angelica Varesi, Aurelien Jacob, Serena Scala, Luca Basso Ricci, Marianna Paulis, Dario Strina, Martina Di Verniere, Lucia Sergi Sergi, Marta Serafini, Steven M. Holland, Jenna R.E. Bergerson, Suk See De Ravin, Harry L. Malech, Francesca Pala, Marita Bosticardo, Chiara Brombin, Federica Cugnata, Enrica Calzoni, Gay M. Crooks, Luigi D. Notarangelo, Pietro Genovese, Luigi Naldini, Anna Villa

Sci Transl Med. Author manuscript; available in PMC 2024 Jun 4.

Published in final edited form as: Sci Transl Med. 2024 Feb 7; 16(733): eadh8162. Published online 2024 Feb 7. doi: 10.1126/scitranslmed.adh8162

PMCID:: PMC11149094

Abstract Article PDF–2.7M

Select item 111488617.

IL-7-primed bystander CD8 tumor-infiltrating lymphocytes optimize the antitumor efficacy of T cell engager immunotherapy

Kun-Joo Lee, Donghoon Choi, Nara Tae, Ha Won Song, Yeon-Woo Kang, Minji Lee, Dain Moon, Youngsik Oh, Sujeong Park, Ji-Hae Kim, Siheon Jeong, Jaehyuk Yang, Uni Park, Da Hee Hong, Mi-Sun Byun, Su-Hyung Park, Joohyuk Sohn, Yunji Park, Sun-Kyoung Im, Sun Shim Choi, Dae Hee Kim, Seung-Woo Lee

Cell Rep Med. 2024 May 21; 5(5): 101567. Published online 2024 May 13. doi: 10.1016/j.xcrm.2024.101567

PMCID:: PMC11148861

Abstract Article PDF–8.6M

Select item 111025488.

Tlr9 deficiency in B cells leads to obesity by promoting inflammation and gut dysbiosis

Pai Wang, Xin Yang, Luyao Zhang, Sha Sha, Juan Huang, Jian Peng, Jianlei Gu, James Alexander Pearson, Youjia Hu, Hongyu Zhao, F. Susan Wong, Quan Wang, Li Wen

Nat Commun. 2024; 15: 4232. Published online 2024 May 18. doi: 10.1038/s41467-024-48611-8

PMCID:: PMC11102548

Abstract Article PDF–3.4M

Select item 110985239.

Ambient oxygen levels regulate intestinal dysbiosis and GVHD severity after allogeneic stem cell transplantation

Keisuke Seike, Anders Kiledal, Hideaki Fujiwara, Israel Henig, Marina Burgos da Silva, Marcel R.M. van den Brink, Robert Hein, Matthew Hoostal, Chen Liu, Katherine Oravecz-Wilson, Emma Lauder, Lu Li, Yaping Sun, Thomas M. Schmidt, Yatrik M. Shah, Robert R. Jenq, Gregory Dick, Pavan Reddy

Immunity. Author manuscript; available in PMC 2024 May 16.

Published in final edited form as: Immunity. 2023 Feb 14; 56(2): 353–368.e6. Published online 2023 Feb 2. doi: 10.1016/j.immuni.2023.01.007

PMCID:: PMC11098523

Abstract Article PDF–3.0M

Select item 1107874710.

PGE₂ limits effector expansion of tumour-infiltrating stem-like CD8⁺ T cells

Sebastian B. Lacher, Janina Dörr, Gustavo P. de Almeida, Julian Hönninger, Felix Bayerl, Anna Hirschberger, Anna-Marie Pedde, Philippa Meiser, Lukas Ramsauer, Thomas J. Rudolph, Nadine Spranger, Matteo Morotti, Alizee J. Grimm, Sebastian Jarosch, Arman Oner, Lisa Gregor, Stefanie Lesch, Stefanos Michaelides, Luisa Fertig, Daria Briukhovetska, Lina Majed, Sophia Stock, Dirk H. Busch, Veit R. Buchholz, Percy A. Knolle, Dietmar Zehn, Denarda Dangaj Laniti, Sebastian Kobold, Jan P. Böttcher

Nature. 2024; 629(8011): 417–425. Published online 2024 Apr 24. doi: 10.1038/s41586-024-07254-x

PMCID:: PMC11078747

Abstract Article PDF–17M

Select item 1106401711.

Aberrant CD8⁺T cells drive reproductive dysfunction in female mice with elevated IFN-γ levels

Enitome E. Bafor, Rebecca A. Erwin-Cohen, Toni Martin, Clayton Baker, Adrienne E. Kimmel, Olivier Duverger, John M. Fenimore, Meredith Ramba, Thea Spindel, Megan M. Hess, Michael Sanford, Vanja Lazarevic, Bérénice A. Benayoun, Howard A. Young, Julio C. Valencia

Front Immunol. 2024; 15: 1368572. Published online 2024 Apr 18. doi: 10.3389/fimmu.2024.1368572

PMCID:: PMC11064017

Abstract Article PDF–9.9M

Select item 1104273712.

Sphingolipid biosynthesis is essential for metabolic rewiring during T_H17 cell differentiation

Thiruvaimozhi Abimannan, Velayoudame Parthibane, Si-Hung Le, Nagampalli Vijaykrishna, Stephen D. Fox, Baktiar Karim, Govind Kunduri, Daniel Blankenberg, Thorkell Andresson, Takeshi Bamba, Usha Acharya, Jairaj K. Acharya

Sci Adv. 2024 Apr 26; 10(17): eadk1045. Published online 2024 Apr 24. doi: 10.1126/sciadv.adk1045

PMCID:: PMC11042737

Abstract Article PDF–7.1M

Select item 1103057713.

Robust anti-tumor immunity and memory in Rag-1-deficient mice following adoptive transfer of cytokine-primed splenocytes and tumor CD80 expression

Priyadarshini L. Ganesan, Stephen I. Alexander, Debbie Watson, Grant J. Logan, Geoff Y. Zhang, Ian E. Alexander

Cancer Immunol Immunother. 2007 Dec; 56(12): 1955–1965. Published online 2007 Jun 5. doi: 10.1007/s00262-007-0339-7

PMCID:: PMC11030577

Abstract Article PDF–494K

Select item 1102985114.

Augmentation of anti-tumor responses of adoptively transferred CD8+T cells in the lymphopenic setting by HSV amplicon transduction

Hovav Nechushtan, Dien Pham, Yu Zhang, Daniel Morgensztern, Kyung H. Yi, Seung-Uon Shin, Howard J. Federoff, William J. Bowers, Khaled A. Tolba, Joseph D. Rosenblatt

Cancer Immunol Immunother. 2008 May; 57(5): 663–675. Published online 2007 Oct 19. doi: 10.1007/s00262-007-0405-1

PMCID:: PMC11029851

Abstract Article PDF–649K

Select item 1100892215.

Mast cells help organize the Peyer’s patch niche for induction of IgA resonses

Marco De Giovanni, Vivasvan S. Vykunta, Adi Biram, Kevin Y. Chen, Hanna Taglinao, Jinping An, Dean Sheppard, Helena Paidassi, Jason G. Cyster

Sci Immunol. Author manuscript; available in PMC 2024 Apr 11.

Published in final edited form as: Sci Immunol. 2024 Mar; 9(93): eadj7363. Published online 2024 Mar 1. doi: 10.1126/sciimmunol.adj7363

PMCID:: PMC11008922

Abstract Article PDF–2.4M

Select item 1098507016.

Dysregulation of Wnt/β-catenin signaling contributes to intestinal inflammation through regulation of group 3 innate lymphoid cells

Jiacheng Hao, Chang Liu, Zhijie Gu, Xuanming Yang, Xun Lan, Xiaohuan Guo

Nat Commun. 2024; 15: 2820. Published online 2024 Apr 1. doi: 10.1038/s41467-024-45616-1

PMCID:: PMC10985070

Abstract Article PDF–5.1M

Select item 1095676017.

Retinoid orphan receptor gamma t (rorγt) promotes inflammatory eosinophilia but is dispensable for innate immune-mediated colitis

Alvaro Torres-Huerta, Katelyn Ruley-Haase, Theodore Reed, Antonia Boger-May, Derek Rubadeux, Lauren Mayer, Arpitha Mysore Rajashekara, Morgan Hiller, Madeleine Frech, Connor Roncagli, Cameron Pedersen, Mary Catherine Camacho, Lauren Hollmer, Lauren English, Grace Kane, David L. Boone

PLoS One. 2024; 19(3): e0300892. Published online 2024 Mar 21. doi: 10.1371/journal.pone.0300892

PMCID:: PMC10956760

Abstract Article PDF–2.9M

Select item 1094734118.

A protein-free vaccine stimulates innate immunity and protects against nosocomial pathogens

Jun Yan, Travis B. Nielsen, Peggy Lu, Yuli Talyansky, Matt Slarve, Hernan Reza, Boris Novakovic, Mihai G. Netea, Ashley E. Keller, Troy Warren, Antonio DiGiandomenico, Bret R. Sellman, Brian M. Luna, Brad Spellberg

Sci Transl Med. Author manuscript; available in PMC 2024 Mar 18.

Published in final edited form as: Sci Transl Med. 2023 Oct 4; 15(716): eadf9556. Published online 2023 Oct 4. doi: 10.1126/scitranslmed.adf9556

PMCID:: PMC10947341

Abstract Article PDF–2.6M

Select item 1092815719.

The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3’-UTR and promoting Rag1 mRNA expression

Meng Xu, Taku Ito-Kureha, Hyun-Seo Kang, Aleksandar Chernev, Timsse Raj, Kai P. Hoefig, Christine Hohn, Florian Giesert, Yinhu Wang, Wenliang Pan, Natalia Ziętara, Tobias Straub, Regina Feederle, Carolin Daniel, Barbara Adler, Julian König, Stefan Feske, George C. Tsokos, Wolfgang Wurst, Henning Urlaub, Michael Sattler, Jan Kisielow, F. Gregory Wulczyn, Marcin Łyszkiewicz, Vigo Heissmeyer

Nat Commun. 2024; 15: 2194. Published online 2024 Mar 11. doi: 10.1038/s41467-024-46371-z

Correction in:: Nat Commun. 2024; 15: 6632.

PMCID:: PMC10928157

Abstract Article PDF–6.4M

Select item 1092351720.

ERG and c-MYC regulate a critical gene network in BCR::ABL1-driven B cell acute lymphoblastic leukemia

Kira Behrens, Natalie Brajanovski, Zhen Xu, Elizabeth M. Viney, Ladina DiRago, Soroor Hediyeh-Zadeh, Melissa J. Davis, Richard B. Pearson, Elaine Sanij, Warren S. Alexander, Ashley P. Ng

Sci Adv. 2024 Mar 8; 10(10): eadj8803. Published online 2024 Mar 8. doi: 10.1126/sciadv.adj8803

PMCID:: PMC10923517

Abstract Article PDF–2.1M

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