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Select item 111139821.

Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10

So Young Lee, Juanma Ramirez, Maribel Franco, Benoît Lectez, Monika Gonzalez, Rosa Barrio, Ugo Mayor

Cell Mol Life Sci. 2014 Jul; 71(14): 2747–2758. Published online 2013 Dec 1. doi: 10.1007/s00018-013-1526-7

PMCID:: PMC11113982

Abstract Article PDF–1.7M

Select item 110349812.

Mrj is a chaperone of the Hsp40 family that regulates Orb2 oligomerization and long-term memory in Drosophila

Meghal Desai, Hemant, Ankita Deo, Jagyanseni Naik, Prathamesh Dhamale, Avinash Kshirsagar, Tania Bose, Amitabha Majumdar

PLoS Biol. 2024 Apr; 22(4): e3002585. Published online 2024 Apr 22. doi: 10.1371/journal.pbio.3002585

PMCID:: PMC11034981

Abstract Article PDF–4.0M

Select item 109425763.

Delta-dependent Notch activation closes the early neuroblast temporal program to promote lineage progression and neurogenesis termination in Drosophila

Chhavi Sood, Md Ausrafuggaman Nahid, Kendall R Branham, Matt Pahl, Susan E Doyle, Sarah E Siegrist

eLife. 2024; 12: RP88565. Published online 2024 Feb 23. doi: 10.7554/eLife.88565

PMCID:: PMC10942576

Abstract Article PDF–7.0M

Select item 109359544.

Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila

Laura Vesala, Yuliya Basikhina, Tea Tuomela, Anssi Nurminen, Emilia Siukola, Pedro F. Vale, Tiina S. Salminen

BMC Biol. 2024; 22: 60. Published online 2024 Mar 13. doi: 10.1186/s12915-024-01858-5

PMCID:: PMC10935954

Abstract Article PDF–2.4M

Select item 106634705.

A distinct Acyl-CoA binding protein (ACBP6) shapes tissue plasticity during nutrient adaptation in Drosophila

Xiaotong Li, Jason Karpac

Nat Commun. 2023; 14: 7599. Published online 2023 Nov 21. doi: 10.1038/s41467-023-43362-4

PMCID:: PMC10663470

Abstract Article PDF–6.8M

Select item 105847556.

Insights into human kidney function from the study of Drosophila

Sybille Koehler, Tobias B. Huber

Pediatr Nephrol. 2023; 38(12): 3875–3887. Published online 2023 May 12. doi: 10.1007/s00467-023-05996-w

PMCID:: PMC10584755

Abstract Article PDF–1.2M

Select item 101109077.

The genetic basis of adaptation to copper pollution in Drosophila melanogaster

Elizabeth R. Everman, Stuart J. Macdonald, John K. Kelly

Front Genet. 2023; 14: 1144221. Published online 2023 Apr 4. doi: 10.3389/fgene.2023.1144221

PMCID:: PMC10110907

Abstract Article PDF–2.0M

Select item 100363708.

Purriato is a conserved small open reading frame gene that interacts with the CASA pathway to regulate muscle homeostasis and epithelial tissue growth in Drosophila

Jose I. Pueyo, Jorge Salazar, Carolina Grincho, Jimena Berni, Benjamin P. Towler, Sarah F. Newbury

Front Cell Dev Biol. 2023; 11: 1117454. Published online 2023 Mar 10. doi: 10.3389/fcell.2023.1117454

PMCID:: PMC10036370

Abstract Article PDF–8.2M

Select item 99679069.

Noncoding RNA Regulation of Hormonal and Metabolic Systems in the Fruit Fly Drosophila

Ki-Kei Chan, Ting-Fung Chan, William Bendena, Jerome H. L. Hui

Metabolites. 2023 Feb; 13(2): 152. Published online 2023 Jan 19. doi: 10.3390/metabo13020152

PMCID:: PMC9967906

Abstract Article PDF–784K

Select item 994597510.

The microbiome stabilizes circadian rhythms in the gut

Yueliang Zhang, Yongjun Li, Annika F. Barber, Sara B. Noya, Julie A. Williams, Fu Li, Scott G. Daniel, Kyle Bittinger, Jichao Fang, Amita Sehgal

Proc Natl Acad Sci U S A. 2023 Jan 31; 120(5): e2217532120. Published online 2023 Jan 23. doi: 10.1073/pnas.2217532120

PMCID:: PMC9945975

Abstract Article PDF–3.9M

Select item 993859011.

Proximity labeling reveals a new in vivo network of interactors for the histone demethylase KDM5

Matanel Yheskel, Simone Sidoli, Julie Secombe

Epigenetics Chromatin. 2023; 16: 8. Published online 2023 Feb 18. doi: 10.1186/s13072-023-00481-y

PMCID:: PMC9938590

Abstract Article PDF–4.8M

Select item 967891612.

Hsc70-4 aggravates PolyQ-mediated neurodegeneration by modulating NF-κB mediated immune response in Drosophila

Saurabh Rai, Madhu G. Tapadia

Front Mol Neurosci. 2022; 15: 857257. Published online 2022 Nov 8. doi: 10.3389/fnmol.2022.857257

PMCID:: PMC9678916

Abstract Article PDF–19M

Select item 952399713.

MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer

Natsumi Tsuboyama, Aileen Patricia Szczepanski, Zibo Zhao, Lu Wang

Genome Biol. 2022; 23: 206. Published online 2022 Sep 30. doi: 10.1186/s13059-022-02776-x

PMCID:: PMC9523997

Abstract Article PDF–6.9M

Select item 947454514.

Mettl3-dependent m⁶A modification attenuates the brain stress response in Drosophila

Alexandra E. Perlegos, Emily J. Shields, Hui Shen, Kathy Fange Liu, Nancy M. Bonini

Nat Commun. 2022; 13: 5387. Published online 2022 Sep 14. doi: 10.1038/s41467-022-33085-3

PMCID:: PMC9474545

Abstract Article PDF–2.7M

Select item 939845215.

Species-specific chromatin landscape determines how transposable elements shape genome evolution

Yuheng Huang, Harsh Shukla, Yuh Chwen G Lee

eLife. 2022; 11: e81567. Published online 2022 Aug 23. doi: 10.7554/eLife.81567

PMCID:: PMC9398452

Abstract Article PDF–5.5M

Select item 928742616.

Fatty acid tryptamide from cacao elongates Drosophila melanogaster lifespan with sirtuin-dependent heat shock protein expression

Kiko Kanno, Yasunari Kayashima, Kazuji Tamura, Takako Miyara, Kento Baba, Megumi Koganei, Midori Natsume, Shinjiro Imai

Sci Rep. 2022; 12: 12080. Published online 2022 Jul 15. doi: 10.1038/s41598-022-16471-1

PMCID:: PMC9287426

Abstract Article PDF–2.1M

Select item 913365317.

Auxilin regulates intestinal stem cell proliferation through EGFR

Hang Zhao, Xuejing Ren, Ruiyan Kong, Lin Shi, Zhengran Li, Runqi Wang, Rui Ma, Huiqing Zhao, Fuli Liu, Henry C. Chang, Chun-Hong Chen, Zhouhua Li

Stem Cell Reports. 2022 May 10; 17(5): 1120–1137. Published online 2022 Apr 14. doi: 10.1016/j.stemcr.2022.03.010

PMCID:: PMC9133653

Abstract Article PDF–7.1M

Select item 912493518.

Hsian-Tsao (Mesona chinensis Benth.) Extract Improves the Thermal Tolerance of Drosophila melanogaster

Yan Huang, Pumo Cai, Xinxin Su, Mingjing Zheng, Wenwen Chi, Shaoling Lin, Zhiwei Huang, Si Qin, Shaoxiao Zeng

Front Nutr. 2022; 9: 819319. Published online 2022 May 9. doi: 10.3389/fnut.2022.819319

Correction in:: Front Nutr. 2022; 9: 953463.

PMCID:: PMC9124935

Abstract Article PDF–15M

Select item 911437019.

Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology

Liberty François-Moutal, David Donald Scott, Andrew J. Ambrose, Christopher J. Zerio, Marina Rodriguez-Sanchez, Kumara Dissanayake, Danielle G. May, Jacob M. Carlson, Edward Barbieri, Aubin Moutal, Kyle J. Roux, James Shorter, Rajesh Khanna, Sami J. Barmada, Leeanne McGurk, May Khanna

Sci Rep. 2022; 12: 8140. Published online 2022 May 17. doi: 10.1038/s41598-022-12191-8

PMCID:: PMC9114370

Abstract Article PDF–2.0M

Select item 903727220.

The tobacco phosphatidylethanolamine-binding protein NtFT4 increases the lifespan of Drosophila melanogaster by interacting with the proteostasis network

Philip Känel, Gundula A. Noll, Katrin Schroedter, Elke Naffin, Julia Kronenberg, Franziska Busswinkel, Richard M. Twyman, Christian Klämbt, Dirk Prüfer

Aging (Albany NY) 2022 Apr 15; 14(7): 2989–3029. Published online 2022 Apr 8. doi: 10.18632/aging.204005