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Select item 111716421.

Conditional Knockout of Neurexins Alters the Contribution of Calcium Channel Subtypes to Presynaptic Ca²⁺ Influx

Johannes Brockhaus, Iris Kahl, Mohiuddin Ahmad, Daniele Repetto, Carsten Reissner, Markus Missler

Cells. 2024 Jun; 13(11): 981. Published online 2024 Jun 5. doi: 10.3390/cells13110981

PMCID:: PMC11171642

Abstract Article PDF–3.7M

Select item 109896852.

Structural and functional characterization of the IgSF21-neurexin2α complex and its related signaling pathways in the regulation of inhibitory synapse organization

Nicolas Chofflet, Yusuke Naito, Anthony John Pastore, Nirmala Padmanabhan, Phuong Trang Nguyen, Christian Poitras, Benjamin Feller, Nayoung Yi, Jeremie Van Prooijen, Husam Khaled, Benoit Coulombe, Steven J. Clapcote, Steve Bourgault, Tabrez J. Siddiqui, Gabby Rudenko, Hideto Takahashi

Front Mol Neurosci. 2024; 17: 1371145. Published online 2024 Mar 20. doi: 10.3389/fnmol.2024.1371145

PMCID:: PMC10989685

Abstract Article PDF–11M

Select item 109484853.

Reprogramming of the developing heart by Hif1a-deficient sympathetic system and maternal diabetes exposure

Hana Kolesova, Petra Hrabalova, Romana Bohuslavova, Pavel Abaffy, Valeria Fabriciova, David Sedmera, Gabriela Pavlinkova

Front Endocrinol (Lausanne) 2024; 15: 1344074. Published online 2024 Mar 5. doi: 10.3389/fendo.2024.1344074

PMCID:: PMC10948485

Abstract Article PDF–7.6M

Select item 109176604.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107693505.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 104355796.

Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit

Alessandra Sclip, Thomas C. Südhof

Nat Commun. 2023; 14: 4976. Published online 2023 Aug 17. doi: 10.1038/s41467-023-40526-0

PMCID:: PMC10435579

Abstract Article PDF–9.2M

Select item 104042577.

Neurexin-3 subsynaptic densities are spatially distinct from Neurexin-1 and essential for excitatory synapse nanoscale organization in the hippocampus

Brian A Lloyd, Ying Han, Rebecca Roth, Bo Zhang, Jason Aoto

Nat Commun. 2023; 14: 4706. Published online 2023 Aug 5. doi: 10.1038/s41467-023-40419-2

PMCID:: PMC10404257

Abstract Article PDF–5.5M

Select item 99979958.

Allelic contribution of Nrxn1α to autism-relevant behavioral phenotypes in mice

Bing Xu, Yugong Ho, Maria Fasolino, Joanna Medina, William Timothy O’Brien, Janine M. Lamonica, Erin Nugent, Edward S. Brodkin, Marc V. Fuccillo, Maja Bucan, Zhaolan Zhou

PLoS Genet. 2023 Feb; 19(2): e1010659. Published online 2023 Feb 27. doi: 10.1371/journal.pgen.1010659

PMCID:: PMC9997995

Abstract Article PDF–3.0M

Select item 98842789.

Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions

Karen Perez de Arce, Adema Ribic, Dhrubajyoti Chowdhury, Katherine Watters, Garth J. Thompson, Basavaraju G. Sanganahalli, Elizabeth T. C. Lippard, Astrid Rohlmann, Stephen M. Strittmatter, Markus Missler, Fahmeed Hyder, Thomas Biederer

Nat Commun. 2023; 14: 459. Published online 2023 Jan 28. doi: 10.1038/s41467-023-36042-w

PMCID:: PMC9884278

Abstract Article PDF–4.0M

Select item 967136810.

Cbln1 regulates axon growth and guidance in multiple neural regions

Peng Han, Yuanchu She, Zhuoxuan Yang, Mengru Zhuang, Qingjun Wang, Xiaopeng Luo, Chaoqun Yin, Junda Zhu, Samie R. Jaffrey, Sheng-Jian Ji

PLoS Biol. 2022 Nov; 20(11): e3001853. Published online 2022 Nov 17. doi: 10.1371/journal.pbio.3001853

PMCID:: PMC9671368

Abstract Article PDF–6.3M

Select item 958655811.

Distinct neurexin-cerebellin complexes control AMPA- and NMDA-receptor responses in a circuit-dependent manner

Jinye Dai, Kif Liakath-Ali, Samantha Rose Golf, Thomas C Südhof

eLife. 2022; 11: e78649. Published online 2022 Oct 7. doi: 10.7554/eLife.78649

Correction in:: eLife. 2023; 12: e94305.

PMCID:: PMC9586558

Abstract Article PDF–8.2M

Select item 880561812.

DSCAM Deficiency Leads to Premature Spine Maturation and Autism-like Behaviors

Peng Chen, Ziyang Liu, Qian Zhang, Dong Lin, Lu Song, Jianghong Liu, Hui-Feng Jiao, Xinsheng Lai, Suqi Zou, Shunqi Wang, Tian Zhou, Bao-Ming Li, Li Zhu, Bing-Xing Pan, Erkang Fei

J Neurosci. 2022 Jan 26; 42(4): 532–551. doi: 10.1523/JNEUROSCI.1003-21.2021

PMCID:: PMC8805618

Abstract Article PDF–6.5M

Select item 868299613.

Molecular self-avoidance in synaptic neurexin complexes

Cosmos Yuqi Wang, Justin H. Trotter, Kif Liakath-Ali, Sung-Jin Lee, Xinran Liu, Thomas C. Südhof

Sci Adv. 2021 Dec; 7(51): eabk1924. Published online 2021 Dec 17. doi: 10.1126/sciadv.abk1924

PMCID:: PMC8682996

Abstract Article PDF–16M

Select item 831323914.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 807135015.

Neurexin1α differentially regulates synaptic efficacy within striatal circuits

M. Felicia Davatolhagh, Marc V. Fuccillo

Cell Rep. Author manuscript; available in PMC 2021 Apr 25.

Published in final edited form as: Cell Rep. 2021 Feb 23; 34(8): 108773. doi: 10.1016/j.celrep.2021.108773

PMCID:: PMC8071350

Abstract Article PDF–2.8M

Select item 806252716.

Neurexins regulate presynaptic GABA_B-receptors at central synapses

Fujun Luo, Alessandra Sclip, Sean Merrill, Thomas C. Südhof

Nat Commun. 2021; 12: 2380. Published online 2021 Apr 22. doi: 10.1038/s41467-021-22753-5

PMCID:: PMC8062527

Abstract Article PDF–5.6M

Select item 775938017.

Disruption of Nrxn1α within excitatory forebrain circuits drives value-based dysfunction

Opeyemi O Alabi, M Felicia Davatolhagh, Mara Robinson, Michael P Fortunato, Luigim Vargas Cifuentes, Joseph W Kable, Marc Vincent Fuccillo

eLife. 2020; 9: e54838. Published online 2020 Dec 4. doi: 10.7554/eLife.54838

PMCID:: PMC7759380

Abstract Article PDF–7.2M

Select item 775806418.

Specific Neuroligin3–αNeurexin1 signaling regulates GABAergic synaptic function in mouse hippocampus

Motokazu Uchigashima, Kohtarou Konno, Emily Demchak, Amy Cheung, Takuya Watanabe, David G Keener, Manabu Abe, Timmy Le, Kenji Sakimura, Toshikuni Sasaoka, Takeshi Uemura, Yuka Imamura Kawasawa, Masahiko Watanabe, Kensuke Futai

eLife. 2020; 9: e59545. Published online 2020 Dec 23. doi: 10.7554/eLife.59545

PMCID:: PMC7758064

Abstract Article PDF–7.0M

Select item 757465219.

SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins

Kathlyn J. Gan, Thomas C. Südhof

J Neurosci. 2020 Oct 14; 40(42): 8088–8102. doi: 10.1523/JNEUROSCI.0454-20.2020

PMCID:: PMC7574652

Abstract Article PDF–6.0M

Select item 748010620.

Deorphanizing FAM19A proteins as pan-neurexin ligands with an unusual biosynthetic binding mechanism

Anna J. Khalaj, Fredrik H. Sterky, Alessandra Sclip, Jochen Schwenk, Axel T. Brunger, Bernd Fakler, Thomas C. Südhof

J Cell Biol. 2020 Sep 7; 219(9): e202004164. Published online 2020 Jul 24. doi: 10.1083/jcb.202004164

PMCID:: PMC7480106

Abstract Article PDF–9.1M

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