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Items: 1 to 20 of 70

1.
Disruption of TIGAR-TAK1 alleviates immunopathology in a murine model of sepsis
Dongdong Wang, Yanxia Li, Hao Yang, Xiaoqi Shen, Xiaolin Shi, Chenyu Li, Yongjing Zhang, Xiaoyu Liu, Bin Jiang, Xudong Zhu, Hanwen Zhang, Xiaoyu Li, Hui Bai, Qing Yang, Wei Gao, Fang Bai, Yong Ji, Qi Chen, Jingjing Ben
Nat Commun. 2024; 15: 4340. Published online 2024 May 21. doi: 10.1038/s41467-024-48708-0
PMCID:
PMC11109194
AbstractArticlePDF–3.1M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
TR4 worsen urosepsis by regulating GSDMD
Huan Wang, Shibin Zhu, Zhenwei Zhou, Zhenghui Wang, Wei Zhuang, Dingwei Xue, Zeyi Lu, Qiming Zheng, Lifeng Ding, Liangliang Ren, Wenqing Luo, Ruyue Wang, Guangju Ge, Liqun Xia, Gonghui Li, Haiyang Wu
Eur J Med Res. 2024; 29: 151. Published online 2024 Mar 1. doi: 10.1186/s40001-024-01742-6
PMCID:
PMC10908015
AbstractArticlePDF–6.5M
4.
Small molecule activators of TAK1 promotes its activity-dependent ubiquitination and TRAIL-mediated tumor cell death
Weimin Sun, Guowei Wu, Xinyu Tian, Chunting Qi, Jingli Liu, Yilun Tong, Mengmeng Zhang, Jiayang Gao, Ze Cao, Yuchao Zhang, Zhijun Liu, Xiaoxu Tian, Ping Wu, Chao Peng, Jingwen Li, Li Tan, Bing Shan, Jianping Liu, Ying Li, Junying Yuan
Proc Natl Acad Sci U S A. 2023 Sep 26; 120(39): e2308079120. Published online 2023 Sep 21. doi: 10.1073/pnas.2308079120
PMCID:
PMC10523529
AbstractArticlePDF–4.3M
5.
TAK1 is essential for endothelial barrier maintenance and repair after lung vascular injury
Dong-Mei Wang, Dheeraj Soni, Sushil C. Regmi, Stephen M. Vogel, Chinnaswamy Tiruppathi
Mol Biol Cell. 2022 Jun 1; 33(7): ar65. Published online 2022 May 25. doi: 10.1091/mbc.E21-11-0563
PMCID:
PMC9561857
AbstractArticlePDF–2.5M
6.
USP10 deubiquitinates Tau, mediating its aggregation
Zhen Wei, Kuan Zeng, Jichang Hu, Xing Li, Fang Huang, Bin Zhang, Jian-Zhi Wang, Rong Liu, Hong-Lian Li, Xiaochuan Wang
Cell Death Dis. 2022 Aug; 13(8): 726. Published online 2022 Aug 20. doi: 10.1038/s41419-022-05170-4
PMCID:
PMC9392799
AbstractArticlePDF–4.7M
7.
Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1
Chen Xu, Zicheng Zhang, Ning Liu, Li Li, Huajian Zhong, Ruizhe Wang, Qianghui Shi, Zifan Zhang, Leixin Wei, Bo Hu, Hao Zhang, Xiaolong Shen, Yue Wang, Yang Liu, Wen Yuan
Nat Commun. 2022; 13: 2467. Published online 2022 May 5. doi: 10.1038/s41467-022-29029-6
PMCID:
PMC9072352
AbstractArticlePDF–12M
8.
Supraphysiological activation of TAK1 promotes skeletal muscle growth and mitigates neurogenic atrophy
Anirban Roy, Ashok Kumar
Nat Commun. 2022; 13: 2201. Published online 2022 Apr 22. doi: 10.1038/s41467-022-29752-0
PMCID:
PMC9033787
AbstractArticlePDF–7.2M
9.
Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation
Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley
Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h
PMCID:
PMC8763317
AbstractArticle
10.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
11.
Deficiency of Lipin2 Results in Enhanced NF-κB Signaling and Osteoclast Formation in RAW-D Murine Macrophages
Asami Watahiki, Seira Hoshikawa, Mitsuki Chiba, Hiroshi Egusa, Satoshi Fukumoto, Hiroyuki Inuzuka
Int J Mol Sci. 2021 Mar; 22(6): 2893. Published online 2021 Mar 12. doi: 10.3390/ijms22062893
PMCID:
PMC8001760
AbstractArticlePDF–16M
12.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
13.
Hepatocyte-specific TAK1 deficiency drives RIPK1 kinase-dependent inflammation to promote liver fibrosis and hepatocellular carcinoma
Shuixia Tan, Jing Zhao, Ziyu Sun, Shuangyi Cao, Kongyan Niu, Yedan Zhong, Han Wang, Linyu Shi, Heling Pan, Junhao Hu, Lihui Qian, Nan Liu, Junying Yuan
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14231–14242. Published online 2020 Jun 8. doi: 10.1073/pnas.2005353117
PMCID:
PMC7322083
AbstractArticlePDF–3.1M
14.
Ablation of spinal cord estrogen receptor α‐expressing interneurons reduces chemically induced modalities of pain and itch
May Tran, Joao Manuel Braz, Katherine Hamel, Julia Kuhn, Andrew J. Todd, Allan I. Basbaum
J Comp Neurol. 2020 Jul; 528(10): 1629–1643. Published online 2020 Jan 6. doi: 10.1002/cne.24847
PMCID:
PMC7317200
AbstractArticlePDF–12M
15.
TBC1D25 Regulates Cardiac Remodeling Through TAK1 Signaling Pathway
Sen Guo, Yuan Liu, Lu Gao, Fankai Xiao, Jihong Shen, Shiying Xing, Fan Yang, Wencai Zhang, Qiangwei Shi, Yan Li, Luosha Zhao
Int J Biol Sci. 2020; 16(8): 1335–1348. Published online 2020 Feb 21. doi: 10.7150/ijbs.41130
PMCID:
PMC7085222
AbstractArticlePDF–2.4M
16.
Hippocalcin-like 4, a neural calcium sensor, has a limited contribution to pain and itch processing
Christopher G. Alvaro, João M. Braz, Mollie Bernstein, Katherine A. Hamel, Veronica Craik, Hiroki Yamanaka, Allan I. Basbaum
PLoS One. 2020; 15(2): e0226289. Published online 2020 Feb 3. doi: 10.1371/journal.pone.0226289
PMCID:
PMC6996964
AbstractArticlePDF–1.8M
17.
Coordinating Tissue Regeneration through TGF-β Activated Kinase 1 (TAK1) In-activation and Re-activation
Hsiao Hsin Sung Hsieh, Shailesh Agarwal, David J. Cholok, Shawn J. Loder, Kieko Kaneko, Amanda Huber, Michael T. Chung, Kavitha Ranganathan, Joe Habbouche, John Li, Jonathan Butts, Jonathan Reimer, Arminder Kaura, James Drake, Christopher Breuler, Caitlin R. Priest, Joe Nguyen, Cameron Brownley, Jonathan Peterson, Serra Ucer Ozgurel, Yashar S. Niknafs, Shuli Li, Maiko Inagaki, Greg Scott, Paul Krebsbach, Michael T. Longaker, Kenneth Westover, Nathanael Gray, Jun-Ninomiya-Tsuji, Yuji Mishina, Benjamin Levi
Stem Cells. Author manuscript; available in PMC 2020 Jun 1.
Published in final edited form as: Stem Cells. 2019 Jun; 37(6): 766–778. Published online 2019 Mar 14. doi: 10.1002/stem.2991
PMCID:
PMC6542699
AbstractArticlePDF–3.5M
18.
Salidroside Regulates Inflammatory Response in Raw 264.7 Macrophages via TLR4/TAK1 and Ameliorates Inflammation in Alcohol Binge Drinking-Induced Liver Injury
Peng Sun, Shun-Zong Song, Shuang Jiang, Xia Li, You-Li Yao, Yan-Ling Wu, Li-Hua Lian, Ji-Xing Nan
Molecules. 2016 Nov; 21(11): 1490. Published online 2016 Nov 9. doi: 10.3390/molecules21111490
PMCID:
PMC6272831
AbstractArticlePDF–3.8M
19.
Molecular Cloning of a Novel Member of the Nuclear Receptor Superfamily Related to the Orphan Receptor, TR2
Simon W. Law, Orla M. Conneely, Bert W. O’Malley
Gene Expr. 1994; 4(1-2): 77–84. Published online 2018 Sep 12.
PMCID:
PMC6134373
AbstractArticlePDF–787K
20.
Myeloid-specific TAK1 deletion results in reduced brain monocyte infiltration and improved outcomes after stroke
Anjali Chauhan, Jacob Hudobenko, Abdullah Al Mamun, Edward C. Koellhoffer, Anthony Patrizz, Rodney M. Ritzel, Bhanu P. Ganesh, Louise D. McCullough
J Neuroinflammation. 2018; 15: 148. Published online 2018 May 17. doi: 10.1186/s12974-018-1188-3
PMCID:
PMC5960093
AbstractArticlePDF–1.9M

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