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Select item 111582701.

Integrin alphavbeta6 mediates the potential for colon cancer cells to colonize in and metastasize to the liver

Guang‐Yun Yang, Ke‐Sen Xu, Zhong‐Qing Pan, Zhao‐Yang Zhang, Yue‐Tang Mi, Jin‐Shen Wang, Rong Chen, Jun Niu

Cancer Sci. 2008 May; 99(5): 879–887. Published online 2008 Feb 20. doi: 10.1111/j.1349-7006.2008.00762.x

PMCID:: PMC11158270

Abstract Article PDF–2.0M

Select item 111569282.

Knockout of integrin αvβ6 protects against renal inflammation in chronic kidney disease by reduction of pro-inflammatory macrophages

Changjian Zhu, Ruilin Zheng, Xu Han, Ziwen Tang, Feng Li, Xinrong Hu, Ruoni Lin, Jiani Shen, Qiaoqiao Pei, Rong Wang, Guangyan Wei, Zhenwei Peng, Wei Chen, Zhou Liang, Yi Zhou

Cell Death Dis. 2024 Jun; 15(6): 397. Published online 2024 Jun 6. doi: 10.1038/s41419-024-06785-5

PMCID:: PMC11156928

Abstract Article PDF–13M

Select item 103207483.

Runx2 activates hepatic stellate cells to promote liver fibrosis via transcriptionally regulating Itgav expression

Li Zhong, Jinqiu Zhao, Lu Huang, Yi Liu, Xiaoxiao Pang, Ke Zhan, Shan Li, Qian Xue, Xiaoli Pan, Liang Deng

Clin Transl Med. 2023 Jul; 13(7): e1316. Published online 2023 Jul 5. doi: 10.1002/ctm2.1316

PMCID:: PMC10320748

Abstract Article PDF–13M

Select item 101785654.

Treadmill Exercise Alleviates Cognition Disorder by Activating the FNDC5: Dual Role of Integrin αV/β5 in Parkinson’s Disease

Chuanxi Tang, Mengting Liu, Zihang Zhou, Hao Li, Chenglin Yang, Li Yang, Jie Xiang

Int J Mol Sci. 2023 May; 24(9): 7830. Published online 2023 Apr 25. doi: 10.3390/ijms24097830

PMCID:: PMC10178565

Abstract Article PDF–4.7M

Select item 99382165.

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes

Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x

PMCID:: PMC9938216

Abstract Article PDF–5.3M

Select item 97910806.

Central Irisin Signaling Is Required for Normal Timing of Puberty in Female Mice

Caroline Decourt, Maggie C Evans, Megan A Inglis, Greg M Anderson

Endocrinology. 2023 Feb; 164(2): bqac208. Published online 2022 Dec 12. doi: 10.1210/endocr/bqac208

PMCID:: PMC9791080

Abstract Article

Select item 91199307.

Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier

Swathi Ayloo, Christopher Gallego Lazo, Shenghuan Sun, Wei Zhang, Bianxiao Cui, Chenghua Gu

Neuron. Author manuscript; available in PMC 2023 May 18.

Published in final edited form as: Neuron. 2022 May 18; 110(10): 1641–1655.e6. Published online 2022 Mar 15. doi: 10.1016/j.neuron.2022.02.017

PMCID:: PMC9119930

Abstract Article PDF–4.7M

Select item 89771008.

The β8 integrin cytoplasmic domain activates extracellular matrix adhesion to promote brain neurovascular development

Arpan De, John E. Morales, Zhihua Chen, Sumod Sebastian, Joseph H. McCarty

Development. 2022 Mar 15; 149(6): dev200472. Published online 2022 Mar 18. doi: 10.1242/dev.200472

PMCID:: PMC8977100

Abstract Article

Select item 87801719.

αVβ3 Integrin Expression Is Essential for Replication of Mosquito and Tick-Borne Flaviviruses in Murine Fibroblast Cells

Vinicius Pinho dos Reis, Markus Keller, Katja Schmidt, Rainer Günter Ulrich, Martin Hermann Groschup

Viruses. 2022 Jan; 14(1): 18. Published online 2021 Dec 23. doi: 10.3390/v14010018

PMCID:: PMC8780171

Abstract Article PDF–2.7M

Select item 855394210.

Regulatory T cells promote cancer immune-escape through integrin αvβ8-mediated TGF-β activation

Alexandra Lainé, Ossama Labiad, Hector Hernandez-Vargas, Sébastien This, Amélien Sanlaville, Sophie Léon, Stéphane Dalle, Dean Sheppard, Mark A. Travis, Helena Paidassi, Julien C. Marie

Nat Commun. 2021; 12: 6228. Published online 2021 Oct 28. doi: 10.1038/s41467-021-26352-2

PMCID:: PMC8553942

Abstract Article PDF–3.2M

Select item 843124911.

αV Integrin Expression and Localization in Male Germ Cells

Veronika Palenikova, Michaela Frolikova, Eliska Valaskova, Pavla Postlerova, Katerina Komrskova

Int J Mol Sci. 2021 Sep; 22(17): 9525. Published online 2021 Sep 2. doi: 10.3390/ijms22179525

PMCID:: PMC8431249

Abstract Article PDF–2.1M

Select item 832141412.

Integrin αvβ8 on T cells suppresses anti-tumor immunity in multiple models and is a promising target for tumor immunotherapy

Eswari Dodagatta-Marri, Hsiao-Yen Ma, Benjia Liang, John Li, Dominique S. Meyer, Szu-Ying Chen, Kai-Hui Sun, Xin Ren, Bahar Zivak, Michael D. Rosenblum, Mark B. Headley, Lauren Pinzas, Nilgun I. Reed, Joselyn S. Del Cid, Byron C. Hann, Sharon Yang, Anand Giddabasappa, Kavon Noorbehesht, Bing Yang, Joseph Dal Porto, Tatsuya Tsukui, Kyle Niessen, Amha Atakilit, Rosemary J. Akhurst, Dean Sheppard

Cell Rep. Author manuscript; available in PMC 2021 Jul 29.

Published in final edited form as: Cell Rep. 2021 Jul 6; 36(1): 109309. doi: 10.1016/j.celrep.2021.109309

PMCID:: PMC8321414

Abstract Article PDF–2.3M

Select item 831323913.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 810630614.

Autoregulation of insulin receptor signaling through MFGE8 and the αvβ5 integrin

Ritwik Datta, Carlos O. Lizama, Amin K. Soltani, William Mckleroy, Michael J. Podolsky, Christopher D. Yang, Tony L. Huynh, Kelly M. Cautivo, Biao Wang, Suneil K. Koliwad, Nada A. Abumrad, Kamran Atabai

Proc Natl Acad Sci U S A. 2021 May 4; 118(18): e2102171118. Published online 2021 Apr 26. doi: 10.1073/pnas.2102171118

PMCID:: PMC8106306

Abstract Article PDF–2.4M

Select item 808511915.

Apoptotic cells in mouse blastocysts are eliminated by neighbouring blastomeres

Jozef Pisko, Alexandra Špirková, Štefan Čikoš, Lucia Olexiková, Veronika Kovaříková, Zuzana Šefčíková, Dušan Fabian

Sci Rep. 2021; 11: 9228. Published online 2021 Apr 29. doi: 10.1038/s41598-021-88752-0

PMCID:: PMC8085119

Abstract Article PDF–1.6M

Select item 801959616.

Tsg101 Is Necessary for the Establishment and Maintenance of Mouse Retinal Pigment Epithelial Cell Polarity

Dai Le, Soyeon Lim, Kwang Wook Min, Joon Woo Park, Youjoung Kim, Taejeong Ha, Kyeong Hwan Moon, Kay-Uwe Wagner, Jin Woo Kim

Mol Cells. 2021 Mar 31; 44(3): 168–178. Published online 2021 Mar 28. doi: 10.14348/molcells.2021.0027

PMCID:: PMC8019596

Abstract Article PDF–34M

Select item 796974117.

Mechanical stress determines the configuration of TGFβ activation in articular cartilage

Gehua Zhen, Qiaoyue Guo, Yusheng Li, Chuanlong Wu, Shouan Zhu, Ruomei Wang, X. Edward Guo, Byoung Choul Kim, Jessie Huang, Yizhong Hu, Yang Dan, Mei Wan, Taekjip Ha, Steven An, Xu Cao

Nat Commun. 2021; 12: 1706. Published online 2021 Mar 17. doi: 10.1038/s41467-021-21948-0

PMCID:: PMC7969741

Abstract Article PDF–3.4M

Select item 782281918.

Discovery of a new class of integrin antibodies for fibrosis

Ji Zhang, Tao Wang, Ashmita Saigal, Josephine Johnson, Jennifer Morrisson, Sahba Tabrizifard, Scott A. Hollingsworth, Michael J. Eddins, Wenxian Mao, Kim O’Neill, Margarita Garcia-Calvo, Ester Carballo-Jane, DingGang Liu, Taewon Ham, Qiong Zhou, Weifeng Dong, Hsien-Wei Meng, Jacqueline Hicks, Tian-Quan Cai, Taro Akiyama, Shirly Pinto, Alan C. Cheng, Thomas Greshock, John C. Marquis, Zhao Ren, Saswata Talukdar, Hussam Hisham Shaheen, Masahisa Handa

Sci Rep. 2021; 11: 2118. Published online 2021 Jan 22. doi: 10.1038/s41598-021-81253-0

PMCID:: PMC7822819

Abstract Article PDF–5.4M

Select item 782250219.

Differential expression of αVβ3 and αVβ6 integrins in prostate cancer progression

Fabio Quaglia, Shiv Ram Krishn, Yanqing Wang, David W. Goodrich, Peter McCue, Andrew V. Kossenkov, Amy C. Mandigo, Karen E. Knudsen, Paul H. Weinreb, Eva Corey, William K. Kelly, Lucia R. Languino

PLoS One. 2021; 16(1): e0244985. Published online 2021 Jan 22. doi: 10.1371/journal.pone.0244985

PMCID:: PMC7822502

Abstract Article PDF–5.6M

Select item 778279220.

Filamentous recombinant human Tau activates primary astrocytes via an integrin receptor complex

Peng Wang, Yihong Ye

Nat Commun. 2021; 12: 95. Published online 2021 Jan 4. doi: 10.1038/s41467-020-20322-w

PMCID:: PMC7782792

Abstract Article PDF–3.5M

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