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Items: 1 to 20 of 36

1.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
2.
Characterization of functionally deficient SIM2 variants found in patients with neurological phenotypes
Emily L. Button, Joseph J. Rossi, Daniel P. McDougal, John B. Bruning, Daniel J. Peet, David C. Bersten, Jill A. Rosenfeld, Murray L. Whitelaw
Biochem J. 2022 Jul 15; 479(13): 1441–1454. Prepublished online 2022 Jun 22. Published online 2022 Jul 13. doi: 10.1042/BCJ20220209
PMCID:
PMC9342896
AbstractArticlePDF–6.8M
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
Long non-coding RNA CASC15 facilitates esophageal squamous cell carcinoma tumorigenesis via decreasing SIM2 stability via FTO-mediated demethylation
Bo Qin, Meng Dong, Zhengyang Wang, Jiajia Wan, Yingying Xie, Yi Jiao, Dan Yan
Oncol Rep. 2021 Mar; 45(3): 1059–1071. Published online 2020 Dec 30. doi: 10.3892/or.2020.7917
PMCID:
PMC7860005
AbstractArticlePDF–1.8M
5.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117
PMCID:
PMC7322067
AbstractArticlePDF–2.7M
6.
Cross-talk between SIM2s and NFκB regulates cyclooxygenase 2 expression in breast cancer
Garhett L. Wyatt, Lyndsey S. Crump, Chloe M. Young, Veronica M. Wessells, Cole M. McQueen, Steven W. Wall, Tanya L. Gustafson, Yang-Yi Fan, Robert S. Chapkin, Weston W. Porter, Traci R. Lyons
Breast Cancer Res. 2019; 21: 131. Published online 2019 Nov 29. doi: 10.1186/s13058-019-1224-y
PMCID:
PMC6884910
AbstractArticlePDF–1.7M
7.
Loss of SIM2s inhibits RAD51 binding and leads to unresolved replication stress
Scott J. Pearson, Jessica Elswood, Rola Barhoumi, Brittini Ming-Whitfield, Monique Rijnkels, Weston W. Porter
Breast Cancer Res. 2019; 21: 125. Published online 2019 Nov 27. doi: 10.1186/s13058-019-1207-z
PMCID:
PMC6882179
AbstractArticlePDF–5.5M
8.
ATM-dependent activation of SIM2s regulates homologous recombination and epithelial-mesenchymal transition
Scott J. Pearson, Tapasree Roy Sarkar, Cole M. McQueen, Jessica Elswood, Emily E. Schmitt, Steven W. Wall, Kelly C. Scribner, Garhett Wyatt, Rola Barhoumi, Fariba Behbod, Monique Rijnkels, Weston W. Porter
Oncogene. Author manuscript; available in PMC 2019 Jun 10.
Published in final edited form as: Oncogene. 2019 Apr; 38(14): 2611–2626. Published online 2018 Dec 10. doi: 10.1038/s41388-018-0622-4
PMCID:
PMC6450754
AbstractArticlePDF–2.8M
9.
The tumor suppressor CIC directly regulates MAPK pathway genes via histone deacetylation
Simon Weissmann, Paul A. Cloos, Simone Sidoli, Ole N. Jensen, Steven Pollard, Kristian Helin
Cancer Res. Author manuscript; available in PMC 2019 Feb 1.
Published in final edited form as: Cancer Res. 2018 Aug 1; 78(15): 4114–4125. Published online 2018 May 29. doi: 10.1158/0008-5472.CAN-18-0342
PMCID:
PMC6076439
AbstractArticlePDF–2.5M
10.
Multiple roles of single‐minded 2 in esophageal squamous cell carcinoma and its clinical implications
Masashi Tamaoki, Rie Komatsuzaki, Masayuki Komatsu, Keiko Minashi, Kazuhiko Aoyagi, Takao Nishimura, Fumiko Chiwaki, Tomoko Hiroki, Hiroyuki Daiko, Kazuhiro Morishita, Yoshiharu Sakai, Hiroshi Seno, Tsutomu Chiba, Manabu Muto, Teruhiko Yoshida, Hiroki Sasaki
Cancer Sci. 2018 Apr; 109(4): 1121–1134. Published online 2018 Feb 25. doi: 10.1111/cas.13531
PMCID:
PMC5891185
AbstractArticlePDF–3.6M
11.
SIM2l attenuates resistance to hypoxia and tumor growth by transcriptional suppression of HIF1A in uterine cervical squamous cell carcinoma
Kanako Nakamura, Masayuki Komatsu, Fumiko Chiwaki, Takashi Takeda, Yusuke Kobayashi, Kouji Banno, Daisuke Aoki, Teruhiko Yoshida, Hiroki Sasaki
Sci Rep. 2017; 7: 14574. Published online 2017 Nov 6. doi: 10.1038/s41598-017-15261-4
PMCID:
PMC5674005
AbstractArticlePDF–6.9M
12.
Circulating mRNAs and miRNAs as candidate markers for the diagnosis and prognosis of prostate cancer
Marilesia Ferreira de Souza, Hellen Kuasne, Mateus de Camargo Barros-Filho, Heloísa Lizotti Cilião, Fabio Albuquerque Marchi, Paulo Emilio Fuganti, Alexandre Rossi Paschoal, Silvia Regina Rogatto, Ilce Mara de Syllos Cólus
PLoS One. 2017; 12(9): e0184094. Published online 2017 Sep 14. doi: 10.1371/journal.pone.0184094
PMCID:
PMC5598937
AbstractArticlePDF–10M
13.
Identification of the Transcription Factor SIM2 as a Potential Biomarker and Immunotherapy Target in Prostate Cancer
MS Arredouani, B Lu, M Bhasin, M Eljanne, W Yue, JM Mosquera, GJ Bubley, V Li, MA Rubin, TA Libermann, MG Sanda
Clin Cancer Res. Author manuscript; available in PMC 2017 Aug 28.
Published in final edited form as: Clin Cancer Res. 2009 Sep 15; 15(18): 5794–5802. Published online 2009 Sep 8. doi: 10.1158/1078-0432.CCR-09-0911
PMCID:
PMC5573151
AbstractArticlePDF–785K
14.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
15.
Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers
Joseph Rosenbluh, Johnathan Mercer, Yashaswi Shrestha, Rachel Oliver, Pablo Tamayo, John G. Doench, Itay Tirosh, Federica Piccioni, Ella Hartenian, Heiko Horn, Lola Fagbami, David E. Root, Jacob Jaffe, Kasper Lage, Jesse S. Boehm, William C. Hahn
Cell Syst. Author manuscript; available in PMC 2017 Sep 28.
Published in final edited form as: Cell Syst. 2016 Sep 28; 3(3): 302–316.e4. doi: 10.1016/j.cels.2016.09.001
PMCID:
PMC5455996
AbstractArticlePDF–3.1M
16.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
17.
Regulation of DCIS to invasive breast cancer progression by Singleminded-2s (SIM2s)
Kelly C. Scribner, Fariba Behbod, Weston W. Porter
Oncogene. Author manuscript; available in PMC 2015 Jun 16.
Published in final edited form as: Oncogene. 2013 May 23; 32(21): 2631–2639. Published online 2012 Jul 9. doi: 10.1038/onc.2012.286
PMCID:
PMC4469191
AbstractArticlePDF–2.6M
18.
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes
Xu Li, Wenqi Wang, Jiadong Wang, Anna Malovannaya, Yuanxin Xi, Wei Li, Rudy Guerra, David H Hawke, Jun Qin, Junjie Chen
Mol Syst Biol. 2015 Jan; 11(1): 775. Published online 2015 Jan 21. doi: 10.15252/msb.20145504
PMCID:
PMC4332150
AbstractArticlePDF–2.8M
19.
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype
Manuel A. R. Ferreira, Melanie C. Matheson, Clara S. Tang, Raquel Granell, Wei Ang, Jennie Hui, Amy K. Kiefer, David L. Duffy, Svetlana Baltic, Patrick Danoy, Minh Bui, Loren Price, Peter D. Sly, Nicholas Eriksson, Pamela A. Madden, Michael J. Abramson, Patrick G. Holt, Andrew C. Heath, Michael Hunter, Bill Musk, Colin F. Robertson, Peter Le Souëf, Grant W. Montgomery, A. John Henderson, Joyce Y. Tung, Shyamali C. Dharmage, Matthew A. Brown, Alan James, Philip J. Thompson, Craig Pennell, Nicholas G. Martin, David M. Evans, David A. Hinds, John L. Hopper, the Australian Asthma Genetics Consortium Collaborators
J Allergy Clin Immunol. Author manuscript; available in PMC 2015 Jun 1.
Published in final edited form as: J Allergy Clin Immunol. 2014 Jun; 133(6): 1564–1571. Published online 2013 Dec 31. doi: 10.1016/j.jaci.2013.10.030
PMCID:
PMC4280183
AbstractArticlePDF–350K
20.
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways
Mikko Taipale, George Tucker, Jian Peng, Irina Krykbaeva, Zhen-Yuan Lin, Brett Larsen, Hyungwon Choi, Bonnie Berger, Anne-Claude Gingras, Susan Lindquist
Cell. Author manuscript; available in PMC 2015 Jul 17.
Published in final edited form as: Cell. 2014 Jul 17; 158(2): 434–448. doi: 10.1016/j.cell.2014.05.039
PMCID:
PMC4104544
AbstractArticlePDF–3.2M

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