PMC Links for GEO Profiles (Select 94372869) - PMC

Select item 100339371.

Assessment of community efforts to advance network-based prediction of protein–protein interactions

Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu

Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7

PMCID:: PMC10033937

Abstract Article PDF–1.5M

Select item 91472832.

Regulator of G-Protein Signaling-4 Attenuates Cardiac Adverse Remodeling and Neuronal Norepinephrine Release-Promoting Free Fatty Acid Receptor FFAR3 Signaling

Alexandra M. Carbone, Jordana I. Borges, Malka S. Suster, Anastasiya Sizova, Natalie Cora, Victoria L. Desimine, Anastasios Lymperopoulos

Int J Mol Sci. 2022 May; 23(10): 5803. Published online 2022 May 22. doi: 10.3390/ijms23105803

PMCID:: PMC9147283

Abstract Article PDF–1.3M

Select item 89990533.

Genetic Inactivation of Free Fatty Acid Receptor 3 Impedes Behavioral Deficits and Pathological Hallmarks in the APP_swe Alzheimer’s Disease Mouse Model

Marta Zamarbide, Eva Martinez-Pinilla, Francisco Gil-Bea, Masashi Yanagisawa, Rafael Franco, Alberto Perez-Mediavilla

Int J Mol Sci. 2022 Apr; 23(7): 3533. Published online 2022 Mar 24. doi: 10.3390/ijms23073533

PMCID:: PMC8999053

Abstract Article PDF–3.1M

Select item 75363844.

FFA2-, but not FFA3-agonists inhibit GSIS of human pseudoislets: a comparative study with mouse islets and rat INS-1E cells

Estela Lorza-Gil, Gabriele Kaiser, Elisabeth Rexen Ulven, Gabriele M. König, Felicia Gerst, Morgana Barroso Oquendo, Andreas L. Birkenfeld, Hans-Ulrich Häring, Evi Kostenis, Trond Ulven, Susanne Ullrich

Sci Rep. 2020; 10: 16497. Published online 2020 Oct 5. doi: 10.1038/s41598-020-73467-5

PMCID:: PMC7536384

Abstract Article PDF–1.5M

Select item 73472675.

The short-chain free fatty acid receptor FFAR3 is expressed and potentiates contraction in human airway smooth muscle

Kentaro Mizuta, Haruka Sasaki, Yi Zhang, Atsuko Matoba, Charles W. Emala, Sr.

Am J Physiol Lung Cell Mol Physiol. 2020 Jun 1; 318(6): L1248–L1260. Published online 2020 Mar 25. doi: 10.1152/ajplung.00357.2019

PMCID:: PMC7347267

Abstract Article

Select item 71699836.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 57311267.

FFAR2-FFAR3 receptor heteromerization modulates short-chain fatty acid sensing

Zhiwei Ang, Ding Xiong, Min Wu, Jeak Ling Ding

FASEB J. 2018 Jan; 32(1): 289–303. Published online 2017 Sep 7. doi: 10.1096/fj.201700252RR

PMCID:: PMC5731126

Abstract Article

Select item 55535688.

A role for mitochondrial translation in promotion of viability in K-Ras mutant cells

Timothy D. Martin, Danielle R. Cook, Mei Yuk Choi, Mamie Z. Li, Kevin M. Haigis, Stephen J. Elledge

Cell Rep. Author manuscript; available in PMC 2017 Aug 11.

Published in final edited form as: Cell Rep. 2017 Jul 11; 20(2): 427–438. doi: 10.1016/j.celrep.2017.06.061

PMCID:: PMC5553568

Abstract Article PDF–1.8M

Select item 52951019.

Soluble Fibre Meal Challenge Reduces Airway Inflammation and Expression of GPR43 and GPR41 in Asthma

Isabel Halnes, Katherine J. Baines, Bronwyn S. Berthon, Lesley K. MacDonald-Wicks, Peter G. Gibson, Lisa G. Wood

Nutrients. 2017 Jan; 9(1): 57. Published online 2017 Jan 10. doi: 10.3390/nu9010057

PMCID:: PMC5295101

Abstract Article PDF–1.0M

Select item 453128610.

Human GPR42 is a transcribed multisite variant that exhibits copy number polymorphism and is functional when heterologously expressed

Henry L. Puhl III, Yu-Jin Won, Van B. Lu, Stephen R. Ikeda

Sci Rep. 2015; 5: 12880. Published online 2015 Aug 11. doi: 10.1038/srep12880

PMCID:: PMC4531286

Abstract Article PDF–1.7M

Select item 351081911.

Extracellular Ionic Locks Determine Variation in Constitutive Activity and Ligand Potency between Species Orthologs of the Free Fatty Acid Receptors FFA2 and FFA3

Brian D. Hudson, Irina G. Tikhonova, Sunil K. Pandey, Trond Ulven, Graeme Milligan

J Biol Chem. 2012 Nov 30; 287(49): 41195–41209. Published online 2012 Oct 12. doi: 10.1074/jbc.M112.396259

PMCID:: PMC3510819

Abstract Article PDF–4.0M

Select item 337019812.

GPR41 Gene Expression Is Mediated by Internal Ribosome Entry Site (IRES)-dependent Translation of Bicistronic mRNA Encoding GPR40 and GPR41 Proteins

Keren Bahar Halpern, Anna Veprik, Nir Rubins, Orly Naaman, Michael D. Walker

J Biol Chem. 2012 Jun 8; 287(24): 20154–20163. Published online 2012 Apr 9. doi: 10.1074/jbc.M112.358887

PMCID:: PMC3370198

Abstract Article PDF–992K

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 306051414.

Selective Orthosteric Free Fatty Acid Receptor 2 (FFA2) Agonists: IDENTIFICATION OF THE STRUCTURAL AND CHEMICAL REQUIREMENTS FOR SELECTIVE ACTIVATION OF FFA2 VERSUS FFA3

Johannes Schmidt, Nicola J. Smith, Elisabeth Christiansen, Irina G. Tikhonova, Manuel Grundmann, Brian D. Hudson, Richard J. Ward, Christel Drewke, Graeme Milligan, Evi Kostenis, Trond Ulven

J Biol Chem. 2011 Mar 25; 286(12): 10628–10640. Published online 2011 Jan 10. doi: 10.1074/jbc.M110.210872