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Select item 109332671.

Interaction network of human early embryonic transcription factors

Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo

EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0

PMCID:: PMC10933267

Abstract Article PDF–2.9M

Select item 108700282.

Discovery of PRDM16‐Mediated TRPA1 Induction as the Mechanism for Low Tubulo‐Interstitial Fibrosis in Diabetic Kidney Disease

Fang Xu, Hongwei Jiang, Xiaozhou Li, Jian Pan, Huiling Li, Luxiang Wang, Pan Zhang, Junxiang Chen, Shuangfa Qiu, Yuxin Xie, Yijian Li, Dongshan Zhang, Zheng Dong

Adv Sci (Weinh) 2024 Feb; 11(7): 2306704. Published online 2023 Dec 10. doi: 10.1002/advs.202306704

PMCID:: PMC10870028

Abstract Article PDF–21M

Select item 105283503.

PRDM16 Deletion Is Associated with Sex-dependent Cardiomyopathy & Cardiac Mortality: A Translational, Multi-institutional Cohort Study

Ryan J. Kramer, Amir Nima Fatahian, Alice Chan, Jeffery Mortenson, Jennifer Osher, Bo Sun, Lauren E. Parker, Michael B. Rosamilia, Kyra B. Potter, Kaila Moore, Sage L. Atkins, Jill A. Rosenfeld, Alona Birjiniuk, Edward Jones, Taylor S. Howard, Jeffrey J. Kim, Daryl A. Scott, Seema Lalani, Omid MT. Rouzbehani, Samantha Kaplan, Marissa A. Hathaway, Jennifer L. Cohen, S. Yukiko Asaki, Hugo R. Martinez, Sihem Boudina, Andrew P. Landstrom

Circ Genom Precis Med. Author manuscript; available in PMC 2024 Aug 1.

Published in final edited form as: Circ Genom Precis Med. 2023 Aug; 16(4): 390–400. Published online 2023 Jul 3. doi: 10.1161/CIRCGEN.122.003912

PMCID:: PMC10528350

Abstract Article PDF–1.5M

Select item 103751294.

Androgen Receptor is a Negative Regulator of PRDM16 in Beige Adipocyte

Shiting Zhao, Tao Nie, Lei Li, Qiaoyun Long, Ping Gu, Yuwei Zhang, Wei Sun, Zexin Lin, Qing Liu, Yue Qi, Wei Wang, Mengyuan Xie, Kerry Loomes, Chenleng Cai, Donghai Wu, Hannah Xiaoyan Hui

Adv Sci (Weinh) 2023 Jul; 10(21): 2300070. Published online 2023 May 21. doi: 10.1002/advs.202300070

PMCID:: PMC10375129

Abstract Article PDF–4.3M

Select item 101389315.

Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage

Sanna Abbasi, Laila Bayat, Caroline Schild-Poulter

Int J Mol Sci. 2023 Apr; 24(8): 7041. Published online 2023 Apr 11. doi: 10.3390/ijms24087041

PMCID:: PMC10138931

Abstract Article PDF–4.0M

Select item 92626146.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 91052357.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 90319718.

Deciphering the Role of the rs2651899, rs10166942, and rs11172113 Polymorphisms in Migraine: A Meta-Analysis

Vasileios Siokas, Ioannis Liampas, Athina-Maria Aloizou, Maria Papasavva, Christos Bakirtzis, Eleftherios Lavdas, Panagiotis Liakos, Nikolaos Drakoulis, Dimitrios P. Bogdanos, Efthimios Dardiotis

Medicina (Kaunas) 2022 Apr; 58(4): 491. Published online 2022 Mar 29. doi: 10.3390/medicina58040491

PMCID:: PMC9031971

Abstract Article PDF–5.7M

Select item 88288959.

Human transcription factor protein interaction networks

Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo

Nat Commun. 2022; 13: 766. Published online 2022 Feb 9. doi: 10.1038/s41467-022-28341-5

PMCID:: PMC8828895

Abstract Article PDF–1.7M

Select item 874863910.

Genomic alterations and evolution of cell clusters in metastatic invasive micropapillary carcinoma of the breast

Qianqian Shi, Kang Shao, Hongqin Jia, Boyang Cao, Weidong Li, Shichen Dong, Jian Liu, Kailiang Wu, Meng Liu, Fangfang Liu, Hanlin Zhou, Jianke Lv, Feng Gu, Luyuan Li, Shida Zhu, Shuai Li, Guibo Li, Li Fu

Nat Commun. 2022; 13: 111. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27794-4

PMCID:: PMC8748639

Abstract Article PDF–2.9M

Select item 816503011.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 797113412.

PRDM16 suppresses HIF-targeted gene expression in kidney cancer

Anirban Kundu, Hyeyoung Nam, Sandeep Shelar, Darshan S. Chandrashekar, Garrett Brinkley, Suman Karki, Tanecia Mitchell, Carolina B. Livi, Phillip Buckhaults, Richard Kirkman, Yawen Tang, Glenn C. Rowe, Shi Wei, Sooryanarayana Varambally, Sunil Sudarshan

J Exp Med. 2020 Jun 1; 217(6): e20191005. Published online 2020 Apr 6. doi: 10.1084/jem.20191005

PMCID:: PMC7971134

Abstract Article PDF–4.9M

Select item 732206713.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 716998314.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 704113115.

PRDM16基因及母亲孕期环境暴露因素与非综合征型唇腭裂相关性研究

殷斌, 石冰, 贾仲林

Hua Xi Kou Qiang Yi Xue Za Zhi. 2018 Oct; 36(5): 503–507. Chinese. doi: 10.7518/hxkq.2018.05.008

PMCID:: PMC7041131

Abstract Article PDF–964K

Select item 694204416.

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity

Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller

Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119

PMCID:: PMC6942044

Abstract Article PDF–10M

Select item 675553817.

Implications for the migraine SNP rs1835740 in a Swedish cluster headache population

Caroline Ran, Carmen Fourier, Margret Zinnegger, Anna Steinberg, Christina Sjöstrand, Elisabet Waldenlind, Andrea Carmine Belin

J Headache Pain. 2018; 19(1): 100. Published online 2018 Nov 1. doi: 10.1186/s10194-018-0937-0

PMCID:: PMC6755538

Abstract Article PDF–677K

Select item 669556018.

PRDM16s transforms megakaryocyte-erythroid progenitors into myeloid leukemia–initiating cells

Tianyuan Hu, Kiyomi Morita, Matthew C. Hill, Yajian Jiang, Ayumi Kitano, Yusuke Saito, Feng Wang, Xizeng Mao, Kevin A. Hoegenauer, Kazuhiro Morishita, James F. Martin, P. Andrew Futreal, Koichi Takahashi, Daisuke Nakada

Blood. 2019 Aug 15; 134(7): 614–625. Prepublished online 2019 Jul 3. doi: 10.1182/blood.2018888255

PMCID:: PMC6695560

Abstract Article

Select item 637966919.

Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex

Danton Ivanochko, Levon Halabelian, Elizabeth Henderson, Pavel Savitsky, Harshika Jain, Edyta Marcon, Shili Duan, Ashley Hutchinson, Alma Seitova, Dalia Barsyte-Lovejoy, Panagis Filippakopoulos, Jack Greenblatt, Evelyne Lima-Fernandes, Cheryl H Arrowsmith

Nucleic Acids Res. 2019 Feb 20; 47(3): 1225–1238. Published online 2018 Nov 20. doi: 10.1093/nar/gky1192

PMCID:: PMC6379669

Abstract Article PDF–7.5M

Select item 634783820.

PRDM16 functions as a suppressor of lung adenocarcinoma metastasis

Liang-Ru Fei, Wen-Jing Huang, Yuan Wang, Lei Lei, Zhi-Han Li, Yi-Wen Zheng, Zhao Wang, Mai-Qing Yang, Chen-Chen Liu, Hong-Tao Xu

J Exp Clin Cancer Res. 2019; 38: 35. Published online 2019 Jan 25. doi: 10.1186/s13046-019-1042-1

PMCID:: PMC6347838

Abstract Article PDF–13M

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