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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 104042862.

Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation

Cornelis J. Boogerd, Ilaria Perini, Eirini Kyriakopoulou, Su Ji Han, Phit La, Britt van der Swaan, Jari B. Berkhout, Danielle Versteeg, Jantine Monshouwer-Kloots, Eva van Rooij

Nat Commun. 2023; 14: 4716. Published online 2023 Aug 5. doi: 10.1038/s41467-023-40203-2

PMCID:: PMC10404286

Abstract Article PDF–3.4M

Select item 102505553.

Myofiber Baf60c controls muscle regeneration by modulating Dkk3-mediated paracrine signaling

Jingya Xu, Xiaofei Li, Wei Chen, Ziyin Zhang, Yanping Zhou, Yahui Gou, Cheng-an Lv, Lu Jin, Xinyuan Qiu, Shengshan Ma, Qing-Qian Wu, Tongyu Liu, Lin Mi, Zhuoying Yang, Ting Yu, Xiaowen Pan, Yu Feng, Pengfei Shan, Zhuo-Xian Meng

J Exp Med. 2023 Sep 4; 220(9): e20221123. Published online 2023 Jun 7. doi: 10.1084/jem.20221123

PMCID:: PMC10250555

Abstract Article PDF–10M

Select item 98492674.

Smarcd3 is an epigenetic modulator of the metabolic landscape in pancreatic ductal adenocarcinoma

L. Paige Ferguson, Jovylyn Gatchalian, Matthew L. McDermott, Mari Nakamura, Kendall Chambers, Nirakar Rajbhandari, Nikki K. Lytle, Sara Brin Rosenthal, Michael Hamilton, Sonia Albini, Martin Wartenberg, Inti Zlobec, José A. Galván, Eva Karamitopoulou, Vera Vavinskaya, Alexis Wascher, Andrew M. Lowy, Christian M. Schürch, Pier Lorenzo Puri, Benoit G. Bruneau, Diana C. Hargreaves, Tannishtha Reya

Nat Commun. 2023; 14: 292. Published online 2023 Jan 18. doi: 10.1038/s41467-023-35796-7

PMCID:: PMC9849267

Abstract Article PDF–3.1M

Select item 96361505.

Lamin A/C-dependent chromatin architecture safeguards naïve pluripotency to prevent aberrant cardiovascular cell fate and function

Yinuo Wang, Adel Elsherbiny, Linda Kessler, Julio Cordero, Haojie Shi, Heike Serke, Olga Lityagina, Felix A. Trogisch, Mona Malek Mohammadi, Ibrahim El-Battrawy, Johannes Backs, Thomas Wieland, Joerg Heineke, Gergana Dobreva

Nat Commun. 2022; 13: 6663. Published online 2022 Nov 4. doi: 10.1038/s41467-022-34366-7

PMCID:: PMC9636150

Abstract Article PDF–8.9M

Select item 96211316.

BAF60c prevents abdominal aortic aneurysm formation through epigenetic control of vascular smooth muscle cell homeostasis

Guizhen Zhao, Yang Zhao, Haocheng Lu, Ziyi Chang, Hongyu Liu, Huilun Wang, Wenying Liang, Yuhao Liu, Tianqing Zhu, Oren Rom, Yanhong Guo, Lin Chang, Bo Yang, Minerva T. Garcia-Barrio, Jiandie D. Lin, Y. Eugene Chen, Jifeng Zhang

J Clin Invest. 2022 Nov 1; 132(21): e158309. Published online 2022 Nov 1. doi: 10.1172/JCI158309

PMCID:: PMC9621131

Abstract Article PDF–29M

Select item 88061057.

Chromatin Remodelers Interact with Eya1 and Six2 to Target Enhancers to Control Nephron Progenitor Cell Maintenance

Jun Li, Jinshu Xu, Huihui Jiang, Ting Zhang, Aarthi Ramakrishnan, Li Shen, Pin-Xian Xu

J Am Soc Nephrol. 2021 Nov; 32(11): 2815–2833. Published online 2021 Nov. doi: 10.1681/ASN.2021040525

PMCID:: PMC8806105

Abstract Article

Select item 83132398.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 80000269.

Chromatin remodelers and lineage-specific factors interact to target enhancers to establish proneurosensory fate within otic ectoderm

Jinshu Xu, Jun Li, Ting Zhang, Huihui Jiang, Aarthi Ramakrishnan, Bernd Fritzsch, Li Shen, Pin-Xian Xu

Proc Natl Acad Sci U S A. 2021 Mar 23; 118(12): e2025196118. Published online 2021 Mar 15. doi: 10.1073/pnas.2025196118

PMCID:: PMC8000026

Abstract Article PDF–3.6M

Select item 761535910.

Characterization of a common progenitor pool of the epicardium and myocardium

Richard C.V. Tyser, Ximena Ibarra-Soria, Katie McDole, Satish A. Jayaram, Jonathan Godwin, Teun A.H. van den Brand, Antonio M.A. Miranda, Antonio Scialdone, Philipp J. Keller, John C. Marioni, Shankar Srinivas

Science. Author manuscript; available in PMC 2023 Dec 18.

Published in final edited form as: Science. 2021 Mar 5; 371(6533): eabb2986. Published online 2021 Jan 7. doi: 10.1126/science.abb2986

PMCID:: PMC7615359

Abstract Article PDF–3.9M

Select item 752001411.

The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation

Jeannine M. Basta, Ajeet P. Singh, Lynn Robbins, Lisa Stout, Michelle Pherson, Michael Rauchman

Dev Biol. Author manuscript; available in PMC 2020 Sep 27.

Published in final edited form as: Dev Biol. 2020 Aug 15; 464(2): 176–187. Published online 2020 Jun 3. doi: 10.1016/j.ydbio.2020.05.008

PMCID:: PMC7520014

Abstract Article PDF–2.6M

Select item 679692612.

Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate

Rui Gao, Xingqun Liang, Sirisha Cheedipudi, Julio Cordero, Xue Jiang, Qingquan Zhang, Luca Caputo, Stefan Günther, Carsten Kuenne, Yonggang Ren, Shoumo Bhattacharya, Xuejun Yuan, Guillermo Barreto, Yihan Chen, Thomas Braun, Sylvia M. Evans, Yunfu Sun, Gergana Dobreva

Cell Res. 2019 Jun; 29(6): 486–501. Published online 2019 Apr 25. doi: 10.1038/s41422-019-0168-1

PMCID:: PMC6796926

Abstract Article PDF–6.5M

Select item 611389013.

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1

Gina E. Elsen, Francesco Bedogni, Rebecca D. Hodge, Theo K. Bammler, James W. MacDonald, Susan Lindtner, John L. R. Rubenstein, Robert F. Hevner

Front Neurosci. 2018; 12: 571. Published online 2018 Aug 22. doi: 10.3389/fnins.2018.00571

PMCID:: PMC6113890

Abstract Article PDF–4.8M

Select item 588528314.

Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes

Maximilian Witzel, Daniel Petersheim, Yanxin Fan, Ehsan Bahrami, Tomas Racek, Meino Rohlfs, Jacek Puchalka, Christian Mertes, Julien Gagneur, Christoph Ziegenhain, Wolfgang Enard, Asbjørg Stray-Pedersen, Peter D Arkwright, Miguel R Abboud, Vahid Pazhakh, Graham J Lieschke, Peter M Krawitz, Maik Dahlhoff, Marlon R Schneider, Eckhard Wolf, Hans-Peter Horny, Heinrich Schmidt, Alejandro A Schäffer, Christoph Klein

Nat Genet. Author manuscript; available in PMC 2018 Apr 5.

Published in final edited form as: Nat Genet. 2017 May; 49(5): 742–752. Published online 2017 Apr 3. doi: 10.1038/ng.3833

PMCID:: PMC5885283

Abstract Article PDF–2.8M

Select item 585800315.

Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes

Aktan Alpsoy, Emily C. Dykhuizen

J Biol Chem. 2018 Mar 16; 293(11): 3892–3903. Published online 2018 Jan 26. doi: 10.1074/jbc.RA117.001065

PMCID:: PMC5858003

Abstract Article PDF–2.5M

Select item 582949916.

Cardiac-enriched BAF chromatin-remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function

Xin Sun, Swetansu K. Hota, Yu-Qing Zhou, Stefanie Novak, Dario Miguel-Perez, Danos Christodoulou, Christine E. Seidman, J. G. Seidman, Carol C. Gregorio, R. Mark Henkelman, Janet Rossant, Benoit G. Bruneau

Biol Open. 2018 Jan 15; 7(1): bio029512. Published online 2017 Nov 28. doi: 10.1242/bio.029512

PMCID:: PMC5829499

Abstract Article PDF–12M

Select item 574114117.

Uncoupling Exercise Bioenergetics From Systemic Metabolic Homeostasis by Conditional Inactivation of Baf60 in Skeletal Muscle

Zhuo-Xian Meng, Weiwei Tao, Jingxia Sun, Qiuyu Wang, Lin Mi, Jiandie D. Lin

Diabetes. 2018 Jan; 67(1): 85–97. Published online 2017 Nov 1. doi: 10.2337/db17-0367

PMCID:: PMC5741141

Abstract Article PDF–2.3M

Select item 548911818.

Glucose sensing by skeletal myocytes couples nutrient signaling to systemic homeostasis

Zhuo-Xian Meng, Jianke Gong, Zhimin Chen, Jingxia Sun, Yuanyuan Xiao, Lin Wang, Yaqiang Li, Jianfeng Liu, X. Z. Shawn Xu, Jiandie D. Lin

Mol Cell. Author manuscript; available in PMC 2018 May 4.

Published in final edited form as: Mol Cell. 2017 May 4; 66(3): 332–344.e4. doi: 10.1016/j.molcel.2017.04.007

PMCID:: PMC5489118

Abstract Article PDF–2.4M

Select item 538630119.

Reduced dosage of β-catenin provides significant rescue of cardiac outflow tract anomalies in a Tbx1 conditional null mouse model of 22q11.2 deletion syndrome

Silvia E. Racedo, Erica Hasten, Mingyan Lin, Gnanapackiam Sheela Devakanmalai, Tingwei Guo, Ertugrul M. Ozbudak, Chen-Leng Cai, Deyou Zheng, Bernice E. Morrow

PLoS Genet. 2017 Mar; 13(3): e1006687. Published online 2017 Mar 27. doi: 10.1371/journal.pgen.1006687

PMCID:: PMC5386301

Abstract Article PDF–3.3M

Select item 509445320.

Corticothalamic projection neuron development beyond subtype specification: Fog2 and intersectional controls regulate intra-class neuronal diversity

Maria J. Galazo, Jason G. Emsley, Jeffrey D. Macklis

Neuron. Author manuscript; available in PMC 2017 Jul 6.

Published in final edited form as: Neuron. 2016 Jul 6; 91(1): 90–106. Published online 2016 Jun 16. doi: 10.1016/j.neuron.2016.05.024

PMCID:: PMC5094453

Abstract Article PDF–1.6M

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